ATE131724T1 - Verfahren zur herstellung von liposomen mit erhöhtem einschlussvermögen bezüglich zu verkapselnder fremdsubstanzen - Google Patents

Verfahren zur herstellung von liposomen mit erhöhtem einschlussvermögen bezüglich zu verkapselnder fremdsubstanzen

Info

Publication number
ATE131724T1
ATE131724T1 AT92901231T AT92901231T ATE131724T1 AT E131724 T1 ATE131724 T1 AT E131724T1 AT 92901231 T AT92901231 T AT 92901231T AT 92901231 T AT92901231 T AT 92901231T AT E131724 T1 ATE131724 T1 AT E131724T1
Authority
AT
Austria
Prior art keywords
pct
encapsulated
foreign substances
producing liposomes
date jun
Prior art date
Application number
AT92901231T
Other languages
German (de)
English (en)
Inventor
Michel Schneider
Herve Tournier
Roland Hyacinthe
Christian Guillot
Bernard Lamy
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Application granted granted Critical
Publication of ATE131724T1 publication Critical patent/ATE131724T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92901231T 1990-12-11 1991-12-09 Verfahren zur herstellung von liposomen mit erhöhtem einschlussvermögen bezüglich zu verkapselnder fremdsubstanzen ATE131724T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90810969 1990-12-11

Publications (1)

Publication Number Publication Date
ATE131724T1 true ATE131724T1 (de) 1996-01-15

Family

ID=8205973

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92901231T ATE131724T1 (de) 1990-12-11 1991-12-09 Verfahren zur herstellung von liposomen mit erhöhtem einschlussvermögen bezüglich zu verkapselnder fremdsubstanzen

Country Status (20)

Country Link
US (1) US5393530A (member.php)
EP (1) EP0514523B1 (member.php)
JP (1) JP3241720B2 (member.php)
KR (1) KR0137783B1 (member.php)
AT (1) ATE131724T1 (member.php)
AU (1) AU635456B2 (member.php)
CA (1) CA2072559C (member.php)
DE (1) DE69115682T2 (member.php)
DK (1) DK0514523T3 (member.php)
ES (1) ES2081605T3 (member.php)
GR (1) GR3018506T3 (member.php)
HU (1) HUT62458A (member.php)
IE (1) IE72163B1 (member.php)
IL (1) IL99835A (member.php)
IN (1) IN172269B (member.php)
IS (1) IS1685B (member.php)
MX (1) MX9102516A (member.php)
NZ (1) NZ240817A (member.php)
WO (1) WO1992010166A1 (member.php)
ZA (1) ZA918489B (member.php)

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Also Published As

Publication number Publication date
JPH05504150A (ja) 1993-07-01
AU635456B2 (en) 1993-03-18
KR920703014A (ko) 1992-12-17
DE69115682D1 (de) 1996-02-01
JP3241720B2 (ja) 2001-12-25
GR3018506T3 (en) 1996-03-31
WO1992010166A1 (en) 1992-06-25
EP0514523A1 (en) 1992-11-25
IE914289A1 (en) 1992-06-17
DK0514523T3 (da) 1996-01-29
HUT62458A (en) 1993-05-28
ZA918489B (en) 1992-07-29
CA2072559A1 (en) 1992-06-12
IS3773A7 (is) 1992-06-12
DE69115682T2 (de) 1996-05-15
IE72163B1 (en) 1997-03-26
MX9102516A (es) 1992-06-01
CA2072559C (en) 1997-03-18
IN172269B (member.php) 1993-05-29
US5393530A (en) 1995-02-28
AU9062991A (en) 1992-07-08
IL99835A (en) 1995-11-27
NZ240817A (en) 1993-01-27
IL99835A0 (en) 1992-08-18
IS1685B (is) 1998-02-24
EP0514523B1 (en) 1995-12-20
ES2081605T3 (es) 1996-03-16
KR0137783B1 (ko) 1998-05-15

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