ES2165971T3 - Suspensiones de liposomas como agentes de contraste para la imagineria de la sangre. - Google Patents

Suspensiones de liposomas como agentes de contraste para la imagineria de la sangre.

Info

Publication number
ES2165971T3
ES2165971T3 ES96901481T ES96901481T ES2165971T3 ES 2165971 T3 ES2165971 T3 ES 2165971T3 ES 96901481 T ES96901481 T ES 96901481T ES 96901481 T ES96901481 T ES 96901481T ES 2165971 T3 ES2165971 T3 ES 2165971T3
Authority
ES
Spain
Prior art keywords
blood
circulation
imaging
contrast agents
blood pool
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96901481T
Other languages
English (en)
Inventor
Herve Tournier
Bernard Lamy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Research SA
Original Assignee
Bracco Research SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Research SA filed Critical Bracco Research SA
Application granted granted Critical
Publication of ES2165971T3 publication Critical patent/ES2165971T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Steroid Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A AGENTES DE CONTRASTE DEL CONJUNTO SANGUINEO INYECTABLES PARA LA VISUALIZACION POR RAYOS X Y NMR. ESTOS AGENTES DEL CONJUNTO SANGUINEO LLEVAN MEJORADORES DE CONTRASTE DE IMAGEN, P.E. PARAMAGNETICOS O, RESPECTIVAMENTE, COMPUESTOS RADIOOPACOS PARA LA VISUALIZACION DE LA CIRCULACION Y/O ORGANOS DE DESTINO DE LA CIRCULACION. LAS COMPOSICIONES DEL AGENTE DEL CONJUNTO SANGUINEO ESTAN FORMULADAS PARA PROTEGER A LOS AGENTES DE CONTRASTE DE SU RETIRADA RAPIDA POR EL SISTEMA RETICULOENDOTELIAL (RES) DEL HIGADO Y BAZO, DE FORMA QUE PERMANEZCAN EN CIRCULACION EL TIEMPO SUFICIENTE PARA PROPORCIONAR BUENAS IMAGENES DE LOS VASOS SANGUINEOS Y ORGANOS PERFUNDIDOS DE SANGRE. LA VISUALIZACION POR RAYOS X Y NMR DE LA CIRCULACION Y DE LOS ORGANOS DE DESTINO PUEDE SER DE GRAN AYUDA EN EL DIAGNOSTICO DE POSIBLES ENFERMEDADES EN PACIENTES HUMANOS Y ANIMALES.
ES96901481T 1995-02-24 1996-02-22 Suspensiones de liposomas como agentes de contraste para la imagineria de la sangre. Expired - Lifetime ES2165971T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95810123 1995-02-24

Publications (1)

Publication Number Publication Date
ES2165971T3 true ES2165971T3 (es) 2002-04-01

Family

ID=8221706

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96901481T Expired - Lifetime ES2165971T3 (es) 1995-02-24 1996-02-22 Suspensiones de liposomas como agentes de contraste para la imagineria de la sangre.

Country Status (13)

Country Link
EP (1) EP0759785B1 (es)
JP (1) JPH10500999A (es)
AT (1) ATE207763T1 (es)
AU (1) AU4546996A (es)
CA (1) CA2187427A1 (es)
DE (1) DE69616453T2 (es)
DK (1) DK0759785T3 (es)
ES (1) ES2165971T3 (es)
FI (1) FI964250A0 (es)
IL (1) IL117248A (es)
NO (1) NO316311B1 (es)
WO (1) WO1996025955A1 (es)
ZA (1) ZA961485B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624918D0 (en) * 1996-11-29 1997-01-15 Nycomed Imaging As Particulate components
KR100824068B1 (ko) * 2000-04-28 2008-04-21 후지필름 홀딩스 가부시끼가이샤 소수성 요오드 화합물을 함유하는 리포솜
EP2286843A3 (en) 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
ITMI20011706A1 (it) * 2001-08-03 2003-02-03 Bracco Imaging Spa Agenti di contrasto radiografici ionici e non ionici, utilizzabili per l'indagine diagnostica combinata tramite raggi-x e risonanza magnetic
US8518373B2 (en) 2001-08-03 2013-08-27 Bracco Imaging Spa Ionic and non-ionic radiographic contrast agents for use in combined X-ray and nuclear magnetic resonance diagnostics
JP2008513533A (ja) * 2004-09-23 2008-05-01 ゲルベ Ｃｅｓｔイメージング用の造影剤封入システム
WO2007129311A2 (en) * 2006-05-04 2007-11-15 Pan Sci Tech S.A. Nano-particles with contrast agents for diagnostic delivery system for x-ray and ct
FR2939318B1 (fr) * 2008-12-10 2012-07-13 Guerbet Sa Systeme d'encapsulation pour imagerie cest avec quelate q superieur ou egal a 2
WO2019010418A1 (en) 2017-07-07 2019-01-10 Drexel University THERAPEUTIC, DIAGNOSTIC AND / OR THERANOSTIC CONSTRUCTS ACTIVATED BY VOLTAGE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920016A (en) * 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
CH672733A5 (es) * 1987-05-22 1989-12-29 Bracco Ind Chimica Spa
IS1685B (is) * 1990-12-11 1998-02-24 Bracco International B.V. Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum
DE69527194T2 (de) * 1994-03-28 2003-02-06 Daiichi Pharmaceutical Co., Ltd. Liposomen enthaltend ein röntgen- oder ultraschallkontrastmittel

Also Published As

Publication number Publication date
JPH10500999A (ja) 1998-01-27
FI964250A (fi) 1996-10-22
EP0759785B1 (en) 2001-10-31
IL117248A (en) 2000-06-29
EP0759785A1 (en) 1997-03-05
ZA961485B (en) 1996-08-28
NO964501L (no) 1996-12-10
IL117248A0 (en) 1996-06-18
AU4546996A (en) 1996-09-11
ATE207763T1 (de) 2001-11-15
DE69616453T2 (de) 2002-07-11
CA2187427A1 (en) 1996-08-29
DK0759785T3 (da) 2002-02-18
NO316311B1 (no) 2004-01-12
FI964250A0 (fi) 1996-10-22
DE69616453D1 (de) 2001-12-06
WO1996025955A1 (en) 1996-08-29
NO964501D0 (no) 1996-10-23

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ES2165971T3 (es) Suspensiones de liposomas como agentes de contraste para la imagineria de la sangre.
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