ATE224737T1 - Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung - Google Patents

Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung

Info

Publication number
ATE224737T1
ATE224737T1 AT96919971T AT96919971T ATE224737T1 AT E224737 T1 ATE224737 T1 AT E224737T1 AT 96919971 T AT96919971 T AT 96919971T AT 96919971 T AT96919971 T AT 96919971T AT E224737 T1 ATE224737 T1 AT E224737T1
Authority
AT
Austria
Prior art keywords
compositions
circulation
mixed micelles
mri
preparation
Prior art date
Application number
AT96919971T
Other languages
English (en)
Inventor
Herve Tournier
Bernard Lamy
Roland Hyacinthe
Original Assignee
Bracco Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8221760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE224737(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bracco Research Sa filed Critical Bracco Research Sa
Application granted granted Critical
Publication of ATE224737T1 publication Critical patent/ATE224737T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
AT96919971T 1995-06-15 1996-06-14 Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung ATE224737T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95810403 1995-06-15
PCT/IB1996/000577 WO1997000087A1 (en) 1995-06-15 1996-06-14 Blood-pool imaging compositions use and method

Publications (1)

Publication Number Publication Date
ATE224737T1 true ATE224737T1 (de) 2002-10-15

Family

ID=8221760

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96919971T ATE224737T1 (de) 1995-06-15 1996-06-14 Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung

Country Status (13)

Country Link
US (1) US5833948A (de)
EP (1) EP0804251B1 (de)
JP (1) JP4335976B2 (de)
KR (1) KR100399712B1 (de)
AT (1) ATE224737T1 (de)
AU (1) AU708328B2 (de)
CA (1) CA2195633C (de)
DE (1) DE69623929T2 (de)
ES (1) ES2180784T3 (de)
NO (1) NO314127B1 (de)
PT (1) PT804251E (de)
WO (1) WO1997000087A1 (de)
ZA (1) ZA965101B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1297035B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
IT1297034B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
US6342598B1 (en) * 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
JP5078212B2 (ja) 2000-06-02 2012-11-21 ブラッコ・スイス・ソシエテ・アノニム 内皮細胞を標的とするための化合物、それを含む組成物およびその使用方法
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20070128253A1 (en) * 2005-04-13 2007-06-07 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US6506413B1 (en) * 2001-04-30 2003-01-14 Joseph C. Ramaekers Compositions for treating animal diseases and syndromes
US20060073197A1 (en) * 2004-05-20 2006-04-06 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US6803046B2 (en) 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
US7553930B2 (en) * 2003-01-06 2009-06-30 Xencor, Inc. BAFF variants and methods thereof
US20050130892A1 (en) * 2003-03-07 2005-06-16 Xencor, Inc. BAFF variants and methods thereof
US20060014248A1 (en) * 2003-01-06 2006-01-19 Xencor, Inc. TNF super family members with altered immunogenicity
US20050221443A1 (en) * 2003-01-06 2005-10-06 Xencor, Inc. Tumor necrosis factor super family agonists
MXPA05007730A (es) 2003-02-04 2006-01-31 Bracco Int Bv Agentes de contraste para ultrasonido y proceso para la preparacion de los mismos.
AU2004279895A1 (en) 2003-10-10 2005-04-21 Xencor, Inc Protein based TNF-alpha variants for the treatment of TNF-alpha related disorders
US9750821B2 (en) 2003-12-22 2017-09-05 Bracco Suisse S.A. Gas-filled microvesicle assembly for contrast imaging
US20050152842A1 (en) * 2003-12-24 2005-07-14 Chun Li Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent
ES2313352T3 (es) * 2004-06-03 2009-03-01 Bracco Research S.A. Ensamblaje de liposomas para uso terapeutico y/o diagnostico.
WO2006018433A1 (en) 2004-08-18 2006-02-23 Bracco Research Sa Gas-filled microvesicles composition for contrast imaging
FR2883562B1 (fr) 2005-03-24 2009-02-27 Guerbet Sa Chelates lipophiles et leur utilisation en imagerie
CN101203249A (zh) * 2005-04-01 2008-06-18 德克萨斯大学体系董事会 多（肽）作为螯合剂：制造方法和用途
US20090130018A1 (en) * 2005-05-31 2009-05-21 Accardo Antonella Supramolecular aggregates containing chelating agents and bioactive peptides as effective and selective delivery tools for drugs and contrast agents in mri or nuclear medicine
US20090053197A1 (en) * 2006-06-14 2009-02-26 Ramaekers Joseph C Transfer Factor Compositions and Methods
US9125874B2 (en) 2007-11-30 2015-09-08 The Ramaekers Family Trust Administration of transfer factor for improving reproductive health
WO2008028917A1 (en) 2006-09-05 2008-03-13 Bracco Research Sa Gas-filled microvesicles with polymer-modified lipids
GB0623838D0 (en) * 2006-11-29 2007-01-10 Malvern Cosmeceutics Ltd Novel compositions
WO2009039256A1 (en) * 2007-09-18 2009-03-26 Ramaekers Nutrition, Llc Growth factor fraction compositions and methods
KR101401217B1 (ko) * 2007-11-07 2014-05-28 충남대학교산학협력단 Ｐｅ－ｄｔｐａ의 새로운 용도
AU2008326324B9 (en) 2007-11-20 2012-11-15 Ambrx, Inc. Modified insulin polypeptides and their uses
WO2009070788A1 (en) * 2007-11-30 2009-06-04 The Ramaekers Family Trust Compositions and methods for enhancing fertility
BRPI0906972B1 (pt) 2008-01-30 2021-09-08 Histogen, Inc Métodos para produção de composições de matriz extracelular e para produção de uma proteína wnt e de um fator de crescimento endotelial vascular
CN106362171A (zh) * 2009-02-13 2017-02-01 华盛顿大学 用于磁共振成像的钆表现脂质纳米颗粒
WO2010139003A1 (en) * 2009-06-01 2010-12-09 Commonwealth Scientific And Industrial Research Organisation Chelating amphiphiles
BR112013003522B1 (pt) 2010-08-17 2021-05-25 Ambrx, Inc. polipeptídeos relaxina modificados compreendendo um aminoácido não codificado naturalmente, seu método de preparação e seu uso, bem como ácido nucleico e célula hospedeira
EP2639227A1 (de) 2012-03-14 2013-09-18 Bracco Imaging S.p.A Neue Klasse von Diazepinderivatchelatbildnern und Komplexe mit paramagnetischen Metallen als MRI-Kontrastmittel
EP2892570B1 (de) 2012-09-07 2019-02-27 Bracco Imaging S.p.A Paramagnetische feste lipidnanopartikel zur kernspinnresonanzbildgebung, die amphiphile metallkomplexe enthalten
ES2825999T3 (es) 2012-09-10 2021-05-17 Xencor Inc Un inhibidor negativo dominante del TNF-alfa para su uso en el tratamiento de trastornos neurológicos del SNC
EP2934740B1 (de) 2012-12-21 2019-12-11 Bracco Suisse SA Gasgefüllte mikrovesikel
WO2015119642A1 (en) 2014-02-10 2015-08-13 The Johns Hopkins University Low oxygen tension enhances endothelial fate of human pluripotent stem cells
US10519207B2 (en) 2015-06-12 2019-12-31 Georgia State University Research Foundation, Inc. Compositions and methods for treating opioid tolerance
US11110063B2 (en) 2017-08-25 2021-09-07 MAIA Pharmaceuticals, Inc. Storage stable sincalide formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387410A (en) * 1983-03-18 1995-02-07 Mallinckrodt, Inc. Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes
US4728575A (en) * 1984-04-27 1988-03-01 Vestar, Inc. Contrast agents for NMR imaging
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
WO1992021017A1 (en) * 1991-05-23 1992-11-26 Unger Evan C Liposoluble compounds for magnetic resonance imaging
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
US5567410A (en) * 1994-06-24 1996-10-22 The General Hospital Corporation Composotions and methods for radiographic imaging

Also Published As

Publication number Publication date
CA2195633A1 (en) 1997-01-03
EP0804251A1 (de) 1997-11-05
AU708328B2 (en) 1999-08-05
US5833948A (en) 1998-11-10
JP4335976B2 (ja) 2009-09-30
CA2195633C (en) 2008-09-16
KR970704477A (ko) 1997-09-06
ES2180784T3 (es) 2003-02-16
NO970665L (no) 1997-04-03
NO314127B1 (no) 2003-02-03
AU5843196A (en) 1997-01-15
NO970665D0 (no) 1997-02-13
DE69623929T2 (de) 2003-05-15
DE69623929D1 (de) 2002-10-31
JPH10504044A (ja) 1998-04-14
EP0804251B1 (de) 2002-09-25
KR100399712B1 (ko) 2004-02-18
WO1997000087A1 (en) 1997-01-03
PT804251E (pt) 2003-01-31
ZA965101B (en) 1997-01-22

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