ATE224737T1 - Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung - Google Patents

Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung

Info

Publication number
ATE224737T1
ATE224737T1 AT96919971T AT96919971T ATE224737T1 AT E224737 T1 ATE224737 T1 AT E224737T1 AT 96919971 T AT96919971 T AT 96919971T AT 96919971 T AT96919971 T AT 96919971T AT E224737 T1 ATE224737 T1 AT E224737T1
Authority
AT
Austria
Prior art keywords
compositions
circulation
mixed micelles
mri
preparation
Prior art date
Application number
AT96919971T
Other languages
English (en)
Inventor
Herve Tournier
Bernard Lamy
Roland Hyacinthe
Original Assignee
Bracco Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8221760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE224737(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bracco Research Sa filed Critical Bracco Research Sa
Application granted granted Critical
Publication of ATE224737T1 publication Critical patent/ATE224737T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
AT96919971T 1995-06-15 1996-06-14 Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung ATE224737T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95810403 1995-06-15
PCT/IB1996/000577 WO1997000087A1 (en) 1995-06-15 1996-06-14 Blood-pool imaging compositions use and method

Publications (1)

Publication Number Publication Date
ATE224737T1 true ATE224737T1 (de) 2002-10-15

Family

ID=8221760

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96919971T ATE224737T1 (de) 1995-06-15 1996-06-14 Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung

Country Status (13)

Country Link
US (1) US5833948A (de)
EP (1) EP0804251B1 (de)
JP (1) JP4335976B2 (de)
KR (1) KR100399712B1 (de)
AT (1) ATE224737T1 (de)
AU (1) AU708328B2 (de)
CA (1) CA2195633C (de)
DE (1) DE69623929T2 (de)
ES (1) ES2180784T3 (de)
NO (1) NO314127B1 (de)
PT (1) PT804251E (de)
WO (1) WO1997000087A1 (de)
ZA (1) ZA965101B (de)

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IT1297035B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
IT1297034B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
US6342598B1 (en) 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
IT1304501B1 (it) * 1998-12-23 2001-03-19 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza
US7109167B2 (en) 2000-06-02 2006-09-19 Bracco International B.V. Compounds for targeting endothelial cells, compositions containing the same and methods for their use
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20060073197A1 (en) * 2004-05-20 2006-04-06 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US20070128253A1 (en) * 2005-04-13 2007-06-07 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US6506413B1 (en) * 2001-04-30 2003-01-14 Joseph C. Ramaekers Compositions for treating animal diseases and syndromes
US6803046B2 (en) 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
US20060014248A1 (en) * 2003-01-06 2006-01-19 Xencor, Inc. TNF super family members with altered immunogenicity
US20050130892A1 (en) * 2003-03-07 2005-06-16 Xencor, Inc. BAFF variants and methods thereof
US7553930B2 (en) * 2003-01-06 2009-06-30 Xencor, Inc. BAFF variants and methods thereof
US20050221443A1 (en) * 2003-01-06 2005-10-06 Xencor, Inc. Tumor necrosis factor super family agonists
WO2004069284A2 (en) 2003-02-04 2004-08-19 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
EP2327723A3 (de) 2003-10-10 2012-06-27 Xencor, Inc. Proteinbasierte TNF-alpha-Varianten zur Behandlung von mit TNF-alpha zusammenhängenden Erkrankungen
JP5513708B2 (ja) 2003-12-22 2014-06-04 ブラッコ・シュイス・ソシエテ・アノニム 造影イメージング用の気体封入マイクロベシクル・アセンブリー
US20050152842A1 (en) * 2003-12-24 2005-07-14 Chun Li Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent
DE602005010424D1 (de) * 2004-06-03 2008-11-27 Bracco Research Sa Liposomale anordnung für die therapeutische und/oder diagnostische anwendung
CN101005858A (zh) 2004-08-18 2007-07-25 伯拉考开发股份有限公司 用于反差成像的充气微泡组合物
FR2883562B1 (fr) 2005-03-24 2009-02-27 Guerbet Sa Chelates lipophiles et leur utilisation en imagerie
EP1888125A2 (de) * 2005-04-01 2008-02-20 Board of Regents of the University of Texas System Poly(peptid) als chelatbildner: verfahren zur herstellung und anwendungen
EP1898958A2 (de) * 2005-05-31 2008-03-19 INBIOS S.r.l. Supramolekulare aggregate mit cheliermitteln und bioaktiven peptiden als effektive und selektive abgabewerkzeuge für arzneimittel und kontrastmittel bei mrt oder in der nuklearmedizin
US20090053197A1 (en) * 2006-06-14 2009-02-26 Ramaekers Joseph C Transfer Factor Compositions and Methods
US9125874B2 (en) 2007-11-30 2015-09-08 The Ramaekers Family Trust Administration of transfer factor for improving reproductive health
AU2007293888B2 (en) 2006-09-05 2013-05-02 Bracco Suisse S.A. Gas-filled microvesicles with polymer-modified lipids
GB0623838D0 (en) * 2006-11-29 2007-01-10 Malvern Cosmeceutics Ltd Novel compositions
WO2009039256A1 (en) * 2007-09-18 2009-03-26 Ramaekers Nutrition, Llc Growth factor fraction compositions and methods
KR101401217B1 (ko) * 2007-11-07 2014-05-28 충남대학교산학협력단 Ｐｅ－ｄｔｐａ의 새로운 용도
ES2632504T3 (es) 2007-11-20 2017-09-13 Ambrx, Inc. Polipéptidos de insulina modificados y sus usos
WO2009070788A1 (en) * 2007-11-30 2009-06-04 The Ramaekers Family Trust Compositions and methods for enhancing fertility
US8257947B2 (en) 2008-01-30 2012-09-04 Naughton Gail K Extracellular matrix compositions produced under hypoxic culture conditions
JP5847588B2 (ja) * 2009-02-13 2016-01-27 ユニヴァーシティ オブ ワシントン 磁気共鳴イメージングのためのガドリニウム発現脂質ナノ粒子
WO2010139003A1 (en) * 2009-06-01 2010-12-09 Commonwealth Scientific And Industrial Research Organisation Chelating amphiphiles
EP2605789B1 (de) 2010-08-17 2019-06-05 Ambrx, Inc. Modifizierte relaxinpolypeptide und ihre verwendungen
EP2639227A1 (de) 2012-03-14 2013-09-18 Bracco Imaging S.p.A Neue Klasse von Diazepinderivatchelatbildnern und Komplexe mit paramagnetischen Metallen als MRI-Kontrastmittel
JP6251744B2 (ja) 2012-09-07 2017-12-20 ブラッコ・イメージング・ソシエタ・ペル・アチオニＢｒａｃｃｏ Ｉｍａｇｉｎｇ Ｓ．Ｐ．Ａ． ＭＲＩ用の両親媒性錯体を含む常磁性固体脂質ナノ粒子（ｐＳＬＮ）
EP2892547B1 (de) 2012-09-10 2020-08-12 Xencor, Inc. Ein dominant-negativer tnf-alpha-inhibitor zur behandlung neurologischer erkrankungen des zns
WO2014096165A2 (en) 2012-12-21 2014-06-26 Bracco Suisse Sa Gas-filled microvesicles
WO2015119642A1 (en) 2014-02-10 2015-08-13 The Johns Hopkins University Low oxygen tension enhances endothelial fate of human pluripotent stem cells
EP3307253A4 (de) 2015-06-12 2018-11-21 Georgia State University Research Foundation, Inc. Zusammensetzungen und verfahren zur behandlung von opioid-toleranz
US11110063B2 (en) 2017-08-25 2021-09-07 MAIA Pharmaceuticals, Inc. Storage stable sincalide formulations
US12077780B2 (en) 2020-02-14 2024-09-03 Allergan Sales, Llc Conditioned medium from cells cultured under hypoxic conditions and uses thereof

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US5387410A (en) * 1983-03-18 1995-02-07 Mallinckrodt, Inc. Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes
US4728575A (en) * 1984-04-27 1988-03-01 Vestar, Inc. Contrast agents for NMR imaging
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
EP0594640A4 (en) * 1991-05-23 1998-06-03 Evan C Unger Liposoluble compounds for magnetic resonance imaging
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
US5567410A (en) * 1994-06-24 1996-10-22 The General Hospital Corporation Composotions and methods for radiographic imaging

Also Published As

Publication number Publication date
AU708328B2 (en) 1999-08-05
KR100399712B1 (ko) 2004-02-18
NO970665L (no) 1997-04-03
KR970704477A (ko) 1997-09-06
EP0804251A1 (de) 1997-11-05
NO970665D0 (no) 1997-02-13
AU5843196A (en) 1997-01-15
CA2195633A1 (en) 1997-01-03
US5833948A (en) 1998-11-10
PT804251E (pt) 2003-01-31
JP4335976B2 (ja) 2009-09-30
CA2195633C (en) 2008-09-16
NO314127B1 (no) 2003-02-03
ES2180784T3 (es) 2003-02-16
DE69623929D1 (de) 2002-10-31
EP0804251B1 (de) 2002-09-25
WO1997000087A1 (en) 1997-01-03
DE69623929T2 (de) 2003-05-15
ZA965101B (en) 1997-01-22
JPH10504044A (ja) 1998-04-14

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