DE69623929D1 - Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung - Google Patents

Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung

Info

Publication number
DE69623929D1
DE69623929D1 DE69623929T DE69623929T DE69623929D1 DE 69623929 D1 DE69623929 D1 DE 69623929D1 DE 69623929 T DE69623929 T DE 69623929T DE 69623929 T DE69623929 T DE 69623929T DE 69623929 D1 DE69623929 D1 DE 69623929D1
Authority
DE
Germany
Prior art keywords
compositions
circulation
mixed micelles
mri
physiologically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69623929T
Other languages
English (en)
Other versions
DE69623929T2 (de
Inventor
Herve Tournier
Bernard Lamy
Roland Hyacinthe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Research SA
Original Assignee
Bracco Research SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8221760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69623929(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bracco Research SA filed Critical Bracco Research SA
Application granted granted Critical
Publication of DE69623929D1 publication Critical patent/DE69623929D1/de
Publication of DE69623929T2 publication Critical patent/DE69623929T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69623929T 1995-06-15 1996-06-14 Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung Expired - Lifetime DE69623929T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95810403 1995-06-15
PCT/IB1996/000577 WO1997000087A1 (en) 1995-06-15 1996-06-14 Blood-pool imaging compositions use and method

Publications (2)

Publication Number Publication Date
DE69623929D1 true DE69623929D1 (de) 2002-10-31
DE69623929T2 DE69623929T2 (de) 2003-05-15

Family

ID=8221760

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69623929T Expired - Lifetime DE69623929T2 (de) 1995-06-15 1996-06-14 Blut-pool bilderzeugungs-zusammensetzungen deren herstellung und verwendung

Country Status (13)

Country Link
US (1) US5833948A (de)
EP (1) EP0804251B1 (de)
JP (1) JP4335976B2 (de)
KR (1) KR100399712B1 (de)
AT (1) ATE224737T1 (de)
AU (1) AU708328B2 (de)
CA (1) CA2195633C (de)
DE (1) DE69623929T2 (de)
ES (1) ES2180784T3 (de)
NO (1) NO314127B1 (de)
PT (1) PT804251E (de)
WO (1) WO1997000087A1 (de)
ZA (1) ZA965101B (de)

Families Citing this family (41)

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Publication number Priority date Publication date Assignee Title
IT1297034B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
IT1297035B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
US6342598B1 (en) 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
US7109167B2 (en) 2000-06-02 2006-09-19 Bracco International B.V. Compounds for targeting endothelial cells, compositions containing the same and methods for their use
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20070128253A1 (en) * 2005-04-13 2007-06-07 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US6506413B1 (en) * 2001-04-30 2003-01-14 Joseph C. Ramaekers Compositions for treating animal diseases and syndromes
US20060073197A1 (en) * 2004-05-20 2006-04-06 Ramaekers Joseph C Encapsulated transfer factor compositions and methods of use
US6803046B2 (en) * 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
US20050221443A1 (en) * 2003-01-06 2005-10-06 Xencor, Inc. Tumor necrosis factor super family agonists
US20060014248A1 (en) * 2003-01-06 2006-01-19 Xencor, Inc. TNF super family members with altered immunogenicity
US20050130892A1 (en) * 2003-03-07 2005-06-16 Xencor, Inc. BAFF variants and methods thereof
US7553930B2 (en) * 2003-01-06 2009-06-30 Xencor, Inc. BAFF variants and methods thereof
CA2512454C (en) 2003-02-04 2012-10-30 Bracco Research Sa Ultrasound contrast agents and process for the preparation thereof
EP2327723A3 (de) 2003-10-10 2012-06-27 Xencor, Inc. Proteinbasierte TNF-alpha-Varianten zur Behandlung von mit TNF-alpha zusammenhängenden Erkrankungen
EP1701745B1 (de) 2003-12-22 2014-12-10 Bracco Suisse S.A. Gasgefüllte mikrovesikel-anordnung für die kontrastdarstellung
WO2005063304A2 (en) * 2003-12-24 2005-07-14 Board Of Regents, The University Of Texas_System Poly (l-glutamic acid) paramagnetic material complex and use as a biodegradable mri contrast agent
US7749485B2 (en) * 2004-06-03 2010-07-06 Bracco Research S.A. Liposomal assembly for therapeutic and/or diagnostic use
AU2005273865B2 (en) 2004-08-18 2011-02-24 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
FR2883562B1 (fr) 2005-03-24 2009-02-27 Guerbet Sa Chelates lipophiles et leur utilisation en imagerie
AU2006232318A1 (en) * 2005-04-01 2006-10-12 The Board Of Regents Of The University Of Texas System Poly(peptide) as a chelator: methods of manufacture and uses
WO2006128643A2 (en) * 2005-05-31 2006-12-07 Inbios S.R.L. Supramolecular aggregates containing chelating agents and bioactive peptides as effective and selective delivery tools for drugs and contrast agents in mri or nuclear medicine
US20090053197A1 (en) * 2006-06-14 2009-02-26 Ramaekers Joseph C Transfer Factor Compositions and Methods
US9125874B2 (en) 2007-11-30 2015-09-08 The Ramaekers Family Trust Administration of transfer factor for improving reproductive health
ATE469660T1 (de) 2006-09-05 2010-06-15 Bracco Research Sa Gasgefüllte mikrovesikel mit polymer- modifizierten lipiden
GB0623838D0 (en) * 2006-11-29 2007-01-10 Malvern Cosmeceutics Ltd Novel compositions
WO2009039256A1 (en) * 2007-09-18 2009-03-26 Ramaekers Nutrition, Llc Growth factor fraction compositions and methods
KR101401217B1 (ko) * 2007-11-07 2014-05-28 충남대학교산학협력단 Ｐｅ－ｄｔｐａ의 새로운 용도
JP5547083B2 (ja) 2007-11-20 2014-07-09 アンブルックス，インコーポレイテッド 修飾されたインスリンポリペプチドおよびそれらの使用
EP2278984A4 (de) * 2007-11-30 2013-02-27 Ramaekers Family Trust Zusammensetzungen und verfahren zur verbesserung der fertilität
KR101650957B1 (ko) 2008-01-30 2016-08-24 히스토젠, 인코포레이티드 세포외 기질 조성물
JP5847588B2 (ja) * 2009-02-13 2016-01-27 ユニヴァーシティ オブ ワシントン 磁気共鳴イメージングのためのガドリニウム発現脂質ナノ粒子
WO2010139003A1 (en) * 2009-06-01 2010-12-09 Commonwealth Scientific And Industrial Research Organisation Chelating amphiphiles
SG10201506443TA (en) 2010-08-17 2015-10-29 Ambrx Inc Modified relaxin polypeptides and their uses
EP2639227A1 (de) 2012-03-14 2013-09-18 Bracco Imaging S.p.A Neue Klasse von Diazepinderivatchelatbildnern und Komplexe mit paramagnetischen Metallen als MRI-Kontrastmittel
ES2726603T3 (es) 2012-09-07 2019-10-08 Bracco Imaging Spa Nanopartículas lipídicas sólidas paramagnéticas (pSLN) que contienen complejos anfifílicos metálicos para IRM
EP2892547B1 (de) 2012-09-10 2020-08-12 Xencor, Inc. Ein dominant-negativer tnf-alpha-inhibitor zur behandlung neurologischer erkrankungen des zns
US10010630B2 (en) 2012-12-21 2018-07-03 Bracco Suisse S.A. Gas-filled microvesicles
US11352606B2 (en) 2014-02-10 2022-06-07 The Johns Hopkins University Low oxygen tension enhances endothelial fate of human pluripotent stem cells
WO2016201409A1 (en) 2015-06-12 2016-12-15 Georgia State University Research Foundation Compositions and methods for treating opioid tolerance
US11110063B2 (en) 2017-08-25 2021-09-07 MAIA Pharmaceuticals, Inc. Storage stable sincalide formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387410A (en) * 1983-03-18 1995-02-07 Mallinckrodt, Inc. Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes
US4728575A (en) * 1984-04-27 1988-03-01 Vestar, Inc. Contrast agents for NMR imaging
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
CA2102605A1 (en) * 1991-05-23 1992-11-24 Evan C. Unger Liposoluble compounds for magnetic resonance imaging
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
US5567410A (en) * 1994-06-24 1996-10-22 The General Hospital Corporation Composotions and methods for radiographic imaging

Also Published As

Publication number Publication date
DE69623929T2 (de) 2003-05-15
EP0804251B1 (de) 2002-09-25
JPH10504044A (ja) 1998-04-14
WO1997000087A1 (en) 1997-01-03
ZA965101B (en) 1997-01-22
AU708328B2 (en) 1999-08-05
CA2195633C (en) 2008-09-16
NO970665L (no) 1997-04-03
NO970665D0 (no) 1997-02-13
NO314127B1 (no) 2003-02-03
KR100399712B1 (ko) 2004-02-18
JP4335976B2 (ja) 2009-09-30
PT804251E (pt) 2003-01-31
US5833948A (en) 1998-11-10
ATE224737T1 (de) 2002-10-15
ES2180784T3 (es) 2003-02-16
CA2195633A1 (en) 1997-01-03
EP0804251A1 (de) 1997-11-05
AU5843196A (en) 1997-01-15
KR970704477A (ko) 1997-09-06

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