ATE469660T1 - Gasgefüllte mikrovesikel mit polymer- modifizierten lipiden - Google Patents

Gasgefüllte mikrovesikel mit polymer- modifizierten lipiden

Info

Publication number
ATE469660T1
ATE469660T1 AT07803220T AT07803220T ATE469660T1 AT E469660 T1 ATE469660 T1 AT E469660T1 AT 07803220 T AT07803220 T AT 07803220T AT 07803220 T AT07803220 T AT 07803220T AT E469660 T1 ATE469660 T1 AT E469660T1
Authority
AT
Austria
Prior art keywords
gas
filled microvesicles
polymer
modified lipids
hydrophilic polymer
Prior art date
Application number
AT07803220T
Other languages
English (en)
Inventor
Stephane Gorgerat
Christian Guillot
Feng Yan
Original Assignee
Bracco Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Research Sa filed Critical Bracco Research Sa
Application granted granted Critical
Publication of ATE469660T1 publication Critical patent/ATE469660T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
    • A61K51/1251—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Tires In General (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
AT07803220T 2006-09-05 2007-09-04 Gasgefüllte mikrovesikel mit polymer- modifizierten lipiden ATE469660T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06120109 2006-09-05
PCT/EP2007/059256 WO2008028917A1 (en) 2006-09-05 2007-09-04 Gas-filled microvesicles with polymer-modified lipids

Publications (1)

Publication Number Publication Date
ATE469660T1 true ATE469660T1 (de) 2010-06-15

Family

ID=37834117

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07803220T ATE469660T1 (de) 2006-09-05 2007-09-04 Gasgefüllte mikrovesikel mit polymer- modifizierten lipiden

Country Status (10)

Country Link
US (1) US9446156B2 (de)
EP (1) EP2061517B1 (de)
JP (1) JP5420410B2 (de)
CN (1) CN101528268B (de)
AT (1) ATE469660T1 (de)
AU (1) AU2007293888B2 (de)
CA (1) CA2662087C (de)
DE (1) DE602007006968D1 (de)
IL (1) IL197380A (de)
WO (1) WO2008028917A1 (de)

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RU2485976C2 (ru) * 2011-05-17 2013-06-27 Государственное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО СибГМУ Минздравсоцразвития России) Контрастное средство для ультразвуковой визуализации
WO2014012168A1 (en) 2012-07-19 2014-01-23 Anirban Ghosh Method for the isolation of microvesicles
TWI552761B (zh) 2013-05-03 2016-10-11 博信生物科技股份有限公司 一種脂質微／奈米氣泡、及其最佳化之製備方法及製備裝置
CN104353088A (zh) * 2014-09-30 2015-02-18 东南大学 一种脂质气泡的制备方法
WO2016102515A1 (en) * 2014-12-22 2016-06-30 Bracco Suisse Sa Gas-filled microvesicles for use as vaccine
WO2017110772A1 (ja) * 2015-12-21 2017-06-29 富士フイルム株式会社 リポソーム及びリポソーム組成物
EP3411082B1 (de) 2016-02-01 2023-06-21 Trust Bio-Sonics Inc. Lipidmikrobläschen und verfahren zur herstellung davon
RU2619353C1 (ru) * 2016-05-27 2017-05-15 государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО СибГМУ Минздрава России) Газосодержащее контрастное средство для ультразвуковой диагностики
US20210389320A1 (en) * 2018-12-21 2021-12-16 Bracco Suisse Sa Gas-filled microvesicles with ligand
CN110272868B (zh) * 2019-07-25 2023-10-20 深圳博雅感知药业有限公司 制备用于细胞分选的链霉亲和素偶联微泡冻干制剂的方法
CN110272867B (zh) * 2019-07-25 2023-10-20 深圳博雅感知药业有限公司 用于细胞分选的链霉亲和素偶联微泡的液体制剂
CN110358731B (zh) * 2019-07-25 2023-11-10 深圳博雅感知药业有限公司 从外周血中直接分离目标细胞的方法
CN110272869B (zh) * 2019-07-25 2023-10-20 深圳博雅感知药业有限公司 细胞分选用链霉亲和素偶联微泡的冻干制剂和用途
CN111265675A (zh) * 2020-02-10 2020-06-12 上海市东方医院（同济大学附属东方医院） 一种用于标记间充质干细胞的超声微泡造影剂及其制备方法
CN114323863B (zh) * 2021-12-31 2023-12-22 吉林大学 一种外泌体阵列捕获探针的制备方法与应用

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JP2006063052A (ja) 2004-08-30 2006-03-09 Konica Minolta Medical & Graphic Inc リポソーム含有超音波造影剤およびその製造方法
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CN1814305A (zh) * 2005-12-09 2006-08-09 重庆医科大学 载基因或药物的超声微泡造影剂及其制备方法

Also Published As

Publication number Publication date
EP2061517B1 (de) 2010-06-02
EP2061517A1 (de) 2009-05-27
JP5420410B2 (ja) 2014-02-19
DE602007006968D1 (de) 2010-07-15
CN101528268A (zh) 2009-09-09
CA2662087C (en) 2015-01-06
AU2007293888A1 (en) 2008-03-13
CN101528268B (zh) 2012-07-04
AU2007293888B2 (en) 2013-05-02
IL197380A (en) 2011-01-31
US9446156B2 (en) 2016-09-20
WO2008028917A1 (en) 2008-03-13
CA2662087A1 (en) 2008-03-13
US20090263330A1 (en) 2009-10-22
JP2010502671A (ja) 2010-01-28

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