ATE111227T1 - Verfahren zur analyse von zellbestandteilen in einer flüssigkeit. - Google Patents
Verfahren zur analyse von zellbestandteilen in einer flüssigkeit.Info
- Publication number
- ATE111227T1 ATE111227T1 AT89306036T AT89306036T ATE111227T1 AT E111227 T1 ATE111227 T1 AT E111227T1 AT 89306036 T AT89306036 T AT 89306036T AT 89306036 T AT89306036 T AT 89306036T AT E111227 T1 ATE111227 T1 AT E111227T1
- Authority
- AT
- Austria
- Prior art keywords
- procedure
- liquid
- cell components
- analyzing cell
- nucleic acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 210000003850 cellular structure Anatomy 0.000 title 1
- 239000007788 liquid Substances 0.000 title 1
- 239000000980 acid dye Substances 0.000 abstract 2
- 239000002458 cell surface marker Substances 0.000 abstract 2
- 238000005259 measurement Methods 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 238000000149 argon plasma sintering Methods 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000011527 multiparameter analysis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Dispersion Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Optical Measuring Cells (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/207,099 US5047321A (en) | 1988-06-15 | 1988-06-15 | Method for analysis of cellular components of a fluid |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE111227T1 true ATE111227T1 (de) | 1994-09-15 |
Family
ID=22769201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89306036T ATE111227T1 (de) | 1988-06-15 | 1989-06-14 | Verfahren zur analyse von zellbestandteilen in einer flüssigkeit. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5047321A (de) |
EP (1) | EP0347210B1 (de) |
JP (1) | JPH0726954B2 (de) |
AT (1) | ATE111227T1 (de) |
AU (1) | AU613197B2 (de) |
CA (1) | CA1340170C (de) |
DE (1) | DE68918004T2 (de) |
DK (1) | DK296889A (de) |
ES (1) | ES2063820T3 (de) |
FI (1) | FI94180C (de) |
NO (1) | NO175506C (de) |
Families Citing this family (96)
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US4963478A (en) * | 1988-07-05 | 1990-10-16 | Immucor, Inc. | Article for preforming immunological assays utilizing organic dyes and method for producing and utilizing same |
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FR2653447B1 (fr) * | 1989-10-20 | 1991-12-27 | Bio Merieux | Procede et reactifs pour la detection de micro-organismes. |
DE69118429T2 (de) * | 1990-01-26 | 1996-09-12 | Canon Kk | Verfahren zur Messung einer Spezies unter Verwendung von Fluoreszenzlicht |
US5229265A (en) * | 1990-03-13 | 1993-07-20 | Litron Laboratories | Process for analyzing clastogenic agents |
US5401847A (en) * | 1990-03-14 | 1995-03-28 | Regents Of The University Of California | DNA complexes with dyes designed for energy transfer as fluorescent markers |
US5622853A (en) * | 1990-05-01 | 1997-04-22 | Becton Dickinson And Company | T lymphocyte precursor |
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WO1992010588A1 (en) * | 1990-12-06 | 1992-06-25 | Affymax Technologies N.V. | Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides |
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EP0586183B1 (de) * | 1992-09-04 | 1999-10-13 | Becton, Dickinson and Company | Kontroll-Teilchen für die Zellzählung und Instrumentenlinearität |
EP0608987B1 (de) * | 1993-01-26 | 2001-10-10 | Becton, Dickinson and Company | Verfahren zum Nachweis von seltenen Ereignissen |
US5294799A (en) * | 1993-02-01 | 1994-03-15 | Aslund Nils R D | Apparatus for quantitative imaging of multiple fluorophores |
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JP7374124B2 (ja) | 2018-04-27 | 2023-11-06 | ベクトン・ディキンソン・アンド・カンパニー | フローサイトメトリで選別された試料のための収集システムおよびそれを使用する方法 |
CN112449680B (zh) | 2018-06-19 | 2024-08-09 | 贝克顿·迪金森公司 | 用于检测器阵列、系统的可变多路复用开关及其使用方法 |
WO2020197787A1 (en) | 2019-03-22 | 2020-10-01 | Becton, Dickinson And Company | Spectral unmixing of fluorescence imaging using radiofrequency-multiplexed excitation data |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3826364A (en) * | 1972-05-22 | 1974-07-30 | Univ Leland Stanford Junior | Particle sorting method and apparatus |
US4284412A (en) * | 1979-07-13 | 1981-08-18 | Ortho Diagnostics, Inc. | Method and apparatus for automated identification and enumeration of specified blood cell subclasses |
US4544546A (en) * | 1980-04-21 | 1985-10-01 | Abbott Laboratories | Fluorescent nucleic acid stains |
US4520110A (en) * | 1981-10-06 | 1985-05-28 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing a phycobiliprotein labeled ligand or receptor |
CA1254134A (en) * | 1984-03-28 | 1989-05-16 | Mount Sinai School Of Medicine Of The City University Of New York | Specific binding flow cytometry method |
US4661913A (en) * | 1984-09-11 | 1987-04-28 | Becton, Dickinson And Company | Apparatus and method for the detection and classification of articles using flow cytometry techniques |
US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
ZA867698B (en) * | 1985-10-11 | 1987-07-29 | Smithkline Beckman Corp | Methods and reagents for performing subset analysis |
CA1279008C (en) * | 1985-10-11 | 1991-01-15 | Smith Kline & French Canada Ltd. | Methods and reagents for performing subset analysis |
US4883867A (en) * | 1985-11-01 | 1989-11-28 | Becton, Dickinson And Company | Detection of reticulocytes, RNA or DNA |
US5016283A (en) * | 1985-11-04 | 1991-05-14 | Cell Analysis Systems, Inc. | Methods and apparatus for immunoploidy analysis |
-
1988
- 1988-06-15 US US07/207,099 patent/US5047321A/en not_active Expired - Lifetime
-
1989
- 1989-06-01 CA CA000601444A patent/CA1340170C/en not_active Expired - Fee Related
- 1989-06-01 AU AU35961/89A patent/AU613197B2/en not_active Ceased
- 1989-06-05 NO NO892302A patent/NO175506C/no unknown
- 1989-06-14 ES ES89306036T patent/ES2063820T3/es not_active Expired - Lifetime
- 1989-06-14 EP EP89306036A patent/EP0347210B1/de not_active Expired - Lifetime
- 1989-06-14 FI FI892926A patent/FI94180C/fi not_active IP Right Cessation
- 1989-06-14 DE DE68918004T patent/DE68918004T2/de not_active Expired - Lifetime
- 1989-06-14 AT AT89306036T patent/ATE111227T1/de not_active IP Right Cessation
- 1989-06-15 JP JP1153564A patent/JPH0726954B2/ja not_active Expired - Lifetime
- 1989-06-15 DK DK296889A patent/DK296889A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI94180B (fi) | 1995-04-13 |
DE68918004T2 (de) | 1995-01-05 |
FI94180C (fi) | 1995-07-25 |
CA1340170C (en) | 1998-12-08 |
NO175506B (no) | 1994-07-11 |
DK296889D0 (da) | 1989-06-15 |
DK296889A (da) | 1989-12-16 |
EP0347210B1 (de) | 1994-09-07 |
NO892302D0 (no) | 1989-06-05 |
EP0347210A2 (de) | 1989-12-20 |
AU3596189A (en) | 1989-12-21 |
EP0347210A3 (en) | 1990-10-17 |
JPH0273157A (ja) | 1990-03-13 |
JPH0726954B2 (ja) | 1995-03-29 |
NO175506C (no) | 1994-10-19 |
US5047321A (en) | 1991-09-10 |
AU613197B2 (en) | 1991-07-25 |
NO892302L (no) | 1989-12-18 |
FI892926A0 (fi) | 1989-06-14 |
ES2063820T3 (es) | 1995-01-16 |
FI892926A (fi) | 1989-12-16 |
DE68918004D1 (de) | 1994-10-13 |
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