ATE81724T1 - Verfahren zur analyse haematopoietischer zellen in einer probe. - Google Patents
Verfahren zur analyse haematopoietischer zellen in einer probe.Info
- Publication number
- ATE81724T1 ATE81724T1 AT88310507T AT88310507T ATE81724T1 AT E81724 T1 ATE81724 T1 AT E81724T1 AT 88310507 T AT88310507 T AT 88310507T AT 88310507 T AT88310507 T AT 88310507T AT E81724 T1 ATE81724 T1 AT E81724T1
- Authority
- AT
- Austria
- Prior art keywords
- sample
- analyzing
- procedure
- haematopoietic cells
- cells
- Prior art date
Links
- 230000003394 haemopoietic effect Effects 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 230000001785 maturational effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11849887A | 1987-11-09 | 1987-11-09 | |
| EP88310507A EP0317156B2 (de) | 1987-11-09 | 1988-11-08 | Verfahren zur Analyse hämatopoietischer Zellen in einer Probe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE81724T1 true ATE81724T1 (de) | 1992-11-15 |
Family
ID=22378975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88310507T ATE81724T1 (de) | 1987-11-09 | 1988-11-08 | Verfahren zur analyse haematopoietischer zellen in einer probe. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5137809A (de) |
| EP (1) | EP0317156B2 (de) |
| JP (1) | JPH06105253B2 (de) |
| AT (1) | ATE81724T1 (de) |
| DE (1) | DE3875456T3 (de) |
| ES (1) | ES2035317T5 (de) |
| GR (2) | GR3006183T3 (de) |
Families Citing this family (82)
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| WO1991013974A1 (en) * | 1990-03-14 | 1991-09-19 | The Biomembrane Institute | Monoclonal antibody and immunoconjugates for the treatment and detection of b cell disorders |
| US5622853A (en) * | 1990-05-01 | 1997-04-22 | Becton Dickinson And Company | T lymphocyte precursor |
| US5367057A (en) | 1991-04-02 | 1994-11-22 | The Trustees Of Princeton University | Tyrosine kinase receptor flk-2 and fragments thereof |
| US5185438A (en) * | 1991-04-02 | 1993-02-09 | The Trustees Of Princeton University | Nucleic acids encoding hencatoporetic stem cell receptor flk-2 |
| GR920100123A (el) * | 1991-04-12 | 1993-03-16 | Ortho Diagnostic Systems Inc | Αντιδραστήριο πολυχρωματικής κηλίδωσης και μέ?οδος ανάλυσης. |
| FR2676847A1 (fr) * | 1991-05-22 | 1992-11-27 | Immunotech Sa | Procede d'enumeration des reticulocytes et les kits destines a cette enumeration. |
| FR2684186B1 (fr) * | 1991-11-25 | 1994-02-25 | Pasteur Sanofi Diagnostics | Trousse pour le denombrement rapide des granulocytes, et procede utilisant ladite trousse. |
| ES2051651B1 (es) * | 1992-12-10 | 1995-01-01 | Univ Salamanca | Procedimiento para la cuantificacion simultanea, en una sola medicion, de los principales tipos de linfocitos humanos y sus subpoblaciones. |
| US5692220A (en) * | 1993-09-02 | 1997-11-25 | Coulter Corporation | Decision support system and method for diagnosis consultation in laboratory hematopathology |
| EP0685071A4 (de) * | 1993-11-12 | 2000-12-13 | Becton Dickinson Co | Verfahren zu absoluter zählung von seltenen zellen |
| FI951778A7 (fi) * | 1995-04-12 | 1996-10-13 | Oy Aboatech Ab | Menetelmä allergian toteamiseksi |
| US5876956A (en) * | 1995-05-15 | 1999-03-02 | Johns Hopkins University School Of Medicine | Methods for identification or purification of cells containing an enzymatic intracellular marker |
| US6117985A (en) * | 1995-06-16 | 2000-09-12 | Stemcell Technologies Inc. | Antibody compositions for preparing enriched cell preparations |
| US6306575B1 (en) | 1995-06-16 | 2001-10-23 | Stemcell Technologies, Inc. | Methods for preparing enriched human hematopoietic cell preparations |
| US5877299A (en) * | 1995-06-16 | 1999-03-02 | Stemcell Technologies Inc. | Methods for preparing enriched human hematopoietic cell preparations |
| ES2194125T3 (es) * | 1995-11-13 | 2003-11-16 | Biotransplant Inc | Procedimiento para el enriquecimiento en volumen de una poblacion o subpoblacion de celulas. |
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| JP3620946B2 (ja) | 1997-03-17 | 2005-02-16 | シスメックス株式会社 | スキャッタグラムの表示方法および粒子計測装置 |
| AU3862200A (en) * | 1999-03-01 | 2000-09-21 | Board Of Trustees Of The Leland Stanford Junior University | Rapid assay for infection in small children |
| AU3712200A (en) * | 1999-03-01 | 2000-09-21 | Board Of Trustees Of The Leland Stanford Junior University | Rapid assay for chorioamnionitis |
| AU763162B2 (en) | 1999-04-13 | 2003-07-17 | Wilex Ag | Diagnostic and therapeutic use of antibodies against the urokinase receptor |
| US6900023B1 (en) | 1999-09-02 | 2005-05-31 | Sysmex Corporation | Method for classifying and counting leukocytes |
| WO2001094936A1 (fr) | 2000-06-08 | 2001-12-13 | Teijin Limited | Nouveau procede permettant de tester la myelotoxicite a l'aide d'un cytometre de flux |
| US7381535B2 (en) * | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
| US7393656B2 (en) * | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
| AU2002365421A1 (en) * | 2001-07-10 | 2003-09-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting the activation state of the multiple proteins in single cells |
| US7695926B2 (en) | 2001-07-10 | 2010-04-13 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting receptor-ligand interactions in single cells |
| PT1363126E (pt) * | 2002-05-14 | 2006-05-31 | Univ Salamanca | Analise multidimensional diferencial de leucocitos |
| NZ537220A (en) * | 2002-05-16 | 2008-06-30 | Absorber Ab | Method of isolating an endothelial cell and method of donor specific crossmatching |
| PT2314629E (pt) * | 2002-07-18 | 2014-01-22 | Merus B V | Produção recombinante de misturas de anticorpos |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| US7507548B2 (en) | 2003-03-04 | 2009-03-24 | University Of Salamanca | Multidimensional detection of aberrant phenotypes in neoplastic cells to be used to monitor minimal disease levels using flow cytometry measurements |
| EP2395016A3 (de) | 2003-05-30 | 2012-12-19 | Merus B.V. | Entwurf und Verwendung von gepaarten unterschiedlichen Regionen von spezifisch bindenden Molekülen |
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| JP3968383B2 (ja) * | 2004-09-01 | 2007-08-29 | 株式会社日本メディカル総研 | 血液細胞の新規分類法ならびにそれを利用したテイラーメード治療および予防 |
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| US7321843B2 (en) * | 2005-09-30 | 2008-01-22 | Universidad De Salamanca | Method for generating new flow cytometry data files containing an infinite number of dimensions based on data estimation |
| AU2005234696B2 (en) | 2005-11-18 | 2012-02-16 | Phanos Technologies, Inc. | Fluorescent membrane intercalating probes and methods for their use |
| EP1984491B1 (de) * | 2006-02-14 | 2016-12-07 | Cellerant Therapeutics, Inc. | Zusammensetzungen für erhöhtes anwachsen blutbildender stammzellen |
| US7816135B2 (en) | 2007-07-05 | 2010-10-19 | Becton, Dickinson And Company | Method of analyzing lymphocytes |
| US8137975B2 (en) | 2007-10-29 | 2012-03-20 | Beckman Coulter, Inc. | Method for a rapid antibody-based analysis of platelet populations |
| AU2009238605B2 (en) | 2008-04-25 | 2014-11-06 | Biogen Idec Hemophilia Inc. | Antibodies against FcRn and use thereof |
| WO2009134944A2 (en) * | 2008-04-29 | 2009-11-05 | Nodality, Inc. | Methods of determining the health status of an individual |
| US20090291458A1 (en) * | 2008-05-22 | 2009-11-26 | Nodality, Inc. | Method for Determining the Status of an Individual |
| US8227202B2 (en) * | 2008-07-10 | 2012-07-24 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
| US8399206B2 (en) | 2008-07-10 | 2013-03-19 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
| EP2349329A4 (de) | 2008-10-14 | 2012-10-31 | Dyax Corp | Verwendung von igf-ii/igf-iie-bindung zur behandlung und prävention von systemischer sklerose im zusammenhang mit lungenfibrose |
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| RS62853B1 (sr) | 2010-01-06 | 2022-02-28 | Takeda Pharmaceuticals Co | Proteini koji vezuju kalikrein plazme |
| US20130210663A1 (en) | 2010-08-04 | 2013-08-15 | Cizzle Biotechnology Limited | Methods and compounds for the diagnosis and treatment of cancer |
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| SG195025A1 (en) | 2011-06-02 | 2013-12-30 | Dyax Corp | Fc RECEPTOR BINDING PROTEINS |
| DK2838917T3 (da) | 2012-04-20 | 2019-08-26 | Merus Nv | Fremgangsmåder og midler til frembringelse af heterodimere ig-lignende molekyler |
| EP2879682B1 (de) | 2012-08-01 | 2018-03-21 | United Therapeutics Corporation | Behandlung von pulmonal-arteriellem hochdruck mit mesenchymalen stammzellen |
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| EA035338B1 (ru) | 2013-10-24 | 2020-05-29 | Нёропласт Бехер Б.В. | Композиция гемопоэтических стволовых клеток с пониженной воспалительной активностью, ее получение и применение |
| KR20180048617A (ko) | 2015-07-20 | 2018-05-10 | 앤지오크린 바이오사이언스 인코포레이티드 | 줄기 세포 이식 방법 및 조성물 |
| EP3362074B1 (de) | 2015-10-16 | 2023-08-09 | President and Fellows of Harvard College | Pd-1-modulation in regulatorischen t-zellen zur regulierung von t-zelleffektorimmunreaktionen |
| WO2017165412A2 (en) | 2016-03-21 | 2017-09-28 | Dana-Farber Cancer Institute, Inc. | T-cell exhaustion state-specific gene expression regulators and uses thereof |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| EP3534917B1 (de) | 2016-10-24 | 2022-08-24 | United Therapeutics Corporation | Verbesserung der msc-immunmodulatorischen eigenschaften durch treprostinil |
| WO2018226293A1 (en) | 2017-06-05 | 2018-12-13 | Becton, Dickinson And Company | Sample indexing for single cells |
| US12227548B2 (en) | 2018-11-19 | 2025-02-18 | Dana-Farber Cancer Institute, Inc. | Use of IRE1α-XBP1 signaling pathway biomarkers for modulating immune responses |
| EP3924506A1 (de) | 2019-02-14 | 2021-12-22 | Becton Dickinson and Company | Hybride gezielte und gesamttranskriptomamplifikation |
| ES2993319T3 (en) | 2020-01-29 | 2024-12-27 | Becton Dickinson Co | Barcoded wells for spatial mapping of single cells through sequencing |
| EP4111168A1 (de) * | 2020-02-25 | 2023-01-04 | Becton Dickinson and Company | Bispezifische sonden zur ermöglichung der verwendung von einzelzellenproben als einzelfarbkompensationssteuerung |
| CN115605614A (zh) | 2020-05-14 | 2023-01-13 | 贝克顿迪金森公司(Us) | 用于免疫组库谱分析的引物 |
| WO2021247593A1 (en) | 2020-06-02 | 2021-12-09 | Becton, Dickinson And Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| US12391940B2 (en) | 2020-07-31 | 2025-08-19 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| EP4263859A1 (de) | 2020-12-15 | 2023-10-25 | Becton, Dickinson and Company | Einzelzellensekretomanalyse |
| US20250319183A1 (en) | 2021-04-07 | 2025-10-16 | David Avigan | Compositions and methods for the treatment of cancer |
| WO2023086969A2 (en) | 2021-11-12 | 2023-05-19 | Ichor Medical Systems Inc. | Treatment methods |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53107413A (en) * | 1977-03-02 | 1978-09-19 | Nippon Baiotesuto Kenkiyuushiy | Detecting method and reagent kit for antibody against leucocyte |
| DE2953610C1 (de) * | 1979-03-19 | 1985-04-11 | International Diagnostic Technology, Inc., Santa Clara, Calif. | Verfahren zum Bestimmen eines immunologisch aktiven Stoffs |
| JPS5745454A (en) * | 1980-09-02 | 1982-03-15 | Fuji Photo Film Co Ltd | Immunochemical measuring method for various minor components |
| JPS58171671A (ja) * | 1982-04-01 | 1983-10-08 | Fujitsu Ltd | 細胞分類方法 |
| US4607007A (en) * | 1983-04-07 | 1986-08-19 | Becton, Dickinson And Company | Differentiation of natural killer cell subpopulations of cells |
| US4581334A (en) * | 1983-04-25 | 1986-04-08 | Ortho Diagnostics Systems, Inc. | Simultaneous detection of leukocyte phagocytic and killing ability |
| US4599307A (en) * | 1983-07-18 | 1986-07-08 | Becton, Dickinson And Company | Method for elimination of selected cell populations in analytic cytology |
| US4645738A (en) * | 1983-09-30 | 1987-02-24 | Memorial Sloan-Kettering Institute Cancer Center | Method for differential diagnosis of T cell leukemias using monoclonal antibodies |
| US4599304A (en) * | 1983-10-07 | 1986-07-08 | Becton, Dickinson And Company | Method for monitoring activated cell subpopulations |
| US4654312A (en) * | 1984-05-14 | 1987-03-31 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
| JPH0652409B2 (ja) * | 1984-08-08 | 1994-07-06 | 富士写真フイルム株式会社 | ハロゲン化銀カラー写真感光材料 |
| US4677061A (en) * | 1984-10-19 | 1987-06-30 | Genetic Systems Corporation | T-cell lymphocyte subset monitoring of immunologic disease |
| US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
| CA1279008C (en) * | 1985-10-11 | 1991-01-15 | Smith Kline & French Canada Ltd. | Methods and reagents for performing subset analysis |
| DE3541033A1 (de) * | 1985-11-19 | 1987-05-21 | Boehringer Mannheim Gmbh | Verfahren zur quantifizierung von zellpopulationen bzw. subpopulationen sowie hierfuer geeignetes reagenz |
-
1988
- 1988-11-08 ES ES88310507T patent/ES2035317T5/es not_active Expired - Lifetime
- 1988-11-08 AT AT88310507T patent/ATE81724T1/de not_active IP Right Cessation
- 1988-11-08 EP EP88310507A patent/EP0317156B2/de not_active Expired - Lifetime
- 1988-11-08 DE DE3875456T patent/DE3875456T3/de not_active Expired - Lifetime
- 1988-11-09 JP JP63283547A patent/JPH06105253B2/ja not_active Expired - Lifetime
-
1990
- 1990-07-19 US US07/572,303 patent/US5137809A/en not_active Expired - Lifetime
-
1992
- 1992-11-05 GR GR920402504T patent/GR3006183T3/el unknown
-
1998
- 1998-01-14 GR GR980400074T patent/GR3025901T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01161153A (ja) | 1989-06-23 |
| EP0317156A1 (de) | 1989-05-24 |
| JPH06105253B2 (ja) | 1994-12-21 |
| ES2035317T5 (es) | 1998-03-16 |
| GR3006183T3 (en) | 1993-06-21 |
| DE3875456T2 (de) | 1993-03-04 |
| DE3875456T3 (de) | 1998-06-10 |
| EP0317156B1 (de) | 1992-10-21 |
| ES2035317T3 (es) | 1993-04-16 |
| US5137809A (en) | 1992-08-11 |
| EP0317156B2 (de) | 1997-11-12 |
| DE3875456D1 (de) | 1992-11-26 |
| GR3025901T3 (en) | 1998-04-30 |
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