ATA10002000A - Antigene zusammensetzung - Google Patents

Antigene zusammensetzung

Info

Publication number
ATA10002000A
ATA10002000A AT0100000A AT10002000A ATA10002000A AT A10002000 A ATA10002000 A AT A10002000A AT 0100000 A AT0100000 A AT 0100000A AT 10002000 A AT10002000 A AT 10002000A AT A10002000 A ATA10002000 A AT A10002000A
Authority
AT
Austria
Prior art keywords
composition
antique
inosin
cytosin
vaccine
Prior art date
Application number
AT0100000A
Other languages
English (en)
Other versions
AT410173B (de
Original Assignee
Cistem Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT0100000A priority Critical patent/AT410173B/de
Application filed by Cistem Biotechnologies Gmbh filed Critical Cistem Biotechnologies Gmbh
Priority to AT01936440T priority patent/ATE290880T1/de
Priority to DE60109443T priority patent/DE60109443T2/de
Priority to AT01960277T priority patent/ATE249839T1/de
Priority to IL15295901A priority patent/IL152959A0/xx
Priority to US10/297,555 priority patent/US8568742B2/en
Priority to MXPA02012010A priority patent/MXPA02012010A/es
Priority to JP2002501476A priority patent/JP5271471B2/ja
Priority to AU2001281812A priority patent/AU2001281812B2/en
Priority to BRPI0111639A priority patent/BRPI0111639B8/pt
Priority to TR200302015T priority patent/TR200302015T4/xx
Priority to PCT/EP2001/006437 priority patent/WO2001093903A1/en
Priority to CZ2002-4168A priority patent/CZ304195B6/cs
Priority to CNB018107974A priority patent/CN1309418C/zh
Priority to DK01960277T priority patent/DK1296713T3/da
Priority to AU2001262345A priority patent/AU2001262345A1/en
Priority to PL358982A priority patent/PL211036B1/pl
Priority to US10/297,497 priority patent/US7148191B2/en
Priority to KR20027016711A priority patent/KR100799788B1/ko
Priority to SI200130047T priority patent/SI1296713T1/xx
Priority to EP01936440A priority patent/EP1286695B1/de
Priority to RU2007103151A priority patent/RU2413520C2/ru
Priority to RU2003100409A priority patent/RU2293573C2/ru
Priority to ES01960277T priority patent/ES2206424T3/es
Priority to PCT/EP2001/006433 priority patent/WO2001093905A1/en
Priority to DE2001600814 priority patent/DE60100814T2/de
Priority to AU8181201A priority patent/AU8181201A/xx
Priority to SK1815-2002A priority patent/SK287689B6/sk
Priority to EP20010960277 priority patent/EP1296713B1/de
Priority to PT01960277T priority patent/PT1296713E/pt
Priority to HU0301229A priority patent/HU228264B1/hu
Priority to CA2411575A priority patent/CA2411575C/en
Publication of ATA10002000A publication Critical patent/ATA10002000A/de
Priority to IS6627A priority patent/IS1993B/is
Priority to IL152959A priority patent/IL152959A/en
Priority to ZA200209479A priority patent/ZA200209479B/en
Priority to NO20025835A priority patent/NO329492B1/no
Application granted granted Critical
Publication of AT410173B publication Critical patent/AT410173B/de
Priority to HK03109011A priority patent/HK1056678A1/xx
Priority to US11/609,777 priority patent/US20070218073A1/en
Priority to JP2013002571A priority patent/JP5908851B2/ja
Priority to US13/786,815 priority patent/US8945591B2/en
Priority to US14/585,740 priority patent/US9492537B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/18—Type of nucleic acid acting by a non-sequence specific mechanism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/33—Chemical structure of the base

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT0100000A 2000-06-08 2000-06-08 Antigene zusammensetzung AT410173B (de)

Priority Applications (41)

Application Number Priority Date Filing Date Title
AT0100000A AT410173B (de) 2000-06-08 2000-06-08 Antigene zusammensetzung
RU2003100409A RU2293573C2 (ru) 2000-06-08 2001-06-07 Иммуностимулирующие олигодезоксинуклеотиды
AT01960277T ATE249839T1 (de) 2000-06-08 2001-06-07 Immunstimulierende oligodeoxynukleotide
DE60109443T DE60109443T2 (de) 2000-06-08 2001-06-07 Antigene zusammensetzung die ein polykationisches peptid und inosin und cytosin enthält
US10/297,555 US8568742B2 (en) 2000-06-08 2001-06-07 Methods and compositions involving immunostimulatory oligodeoxynucleotides
MXPA02012010A MXPA02012010A (es) 2000-06-08 2001-06-07 Oligodesoxinucleotidos inmunoestimulantes.
JP2002501476A JP5271471B2 (ja) 2000-06-08 2001-06-07 免疫促進性オリゴデオキシヌクレオチド
AU2001281812A AU2001281812B2 (en) 2000-06-08 2001-06-07 Immunostimulatory oligodeoxynucleotides
BRPI0111639A BRPI0111639B8 (pt) 2000-06-08 2001-06-07 uso de uma molécula de ácido oligodeoxinucléico imunoestimulatório e composição farmacêutica.
TR200302015T TR200302015T4 (tr) 2000-06-08 2001-06-07 İmüno-uyarıcı oligodeoksinükleotitler
PCT/EP2001/006437 WO2001093903A1 (en) 2000-06-08 2001-06-07 Antigenic composition comprising a polycationic peptide and inosine and cytosine
CZ2002-4168A CZ304195B6 (cs) 2000-06-08 2001-06-07 Imunostimulační farmaceutický přípravek
CNB018107974A CN1309418C (zh) 2000-06-08 2001-06-07 免疫刺激性寡脱氧核苷酸
DK01960277T DK1296713T3 (da) 2000-06-08 2001-06-07 Immunstimulerende oligodeoxynukleotider
AU2001262345A AU2001262345A1 (en) 2000-06-08 2001-06-07 Antigenic composition comprising a polycationic peptide and inosine and cytosine
ES01960277T ES2206424T3 (es) 2000-06-08 2001-06-07 Oligodesoxinucleotidos inmunoestimulantes.
US10/297,497 US7148191B2 (en) 2000-06-08 2001-06-07 Antigenic composition
KR20027016711A KR100799788B1 (ko) 2000-06-08 2001-06-07 면역촉진성 올리고디옥시뉴클레오티드
SI200130047T SI1296713T1 (en) 2000-06-08 2001-06-07 Immunostimulatory oligodeoxynucleotides
EP01936440A EP1286695B1 (de) 2000-06-08 2001-06-07 Antigene zusammensetzung die ein polykationisches peptid und inosin und cytosin enthält
AT01936440T ATE290880T1 (de) 2000-06-08 2001-06-07 Antigene zusammensetzung die ein polykationisches peptid und inosin und cytosin enthält
IL15295901A IL152959A0 (en) 2000-06-08 2001-06-07 Immunostimulatory oligodeoxynucleotides
PL358982A PL211036B1 (pl) 2000-06-08 2001-06-07 Zastosowanie cząsteczki immunostymulującego kwasu oligodezoksynukleinowego (ODN) i zawierająca ją kompozycja
PCT/EP2001/006433 WO2001093905A1 (en) 2000-06-08 2001-06-07 Immunostimulatory oligodeoxynucleotides
DE2001600814 DE60100814T2 (de) 2000-06-08 2001-06-07 Immunstimulierende oligodeoxynukleotide
AU8181201A AU8181201A (en) 2000-06-08 2001-06-07 Immunostimulatory oligodeoxynucleotides
SK1815-2002A SK287689B6 (sk) 2000-06-08 2001-06-07 Použitie molekuly oligodeoxynukleovej kyseliny na výrobu imunostimulačnej farmaceutickej kompozície a farmaceutický prípravok
EP20010960277 EP1296713B1 (de) 2000-06-08 2001-06-07 Immunstimulierende oligodeoxynukleotide
PT01960277T PT1296713E (pt) 2000-06-08 2001-06-07 Oligodesoxinucleotidos imunoestimuladores
HU0301229A HU228264B1 (en) 2000-06-08 2001-06-07 Immunostimulatory oligodeoxynucleotides
CA2411575A CA2411575C (en) 2000-06-08 2001-06-07 Immunostimulatory oligodeoxynucleotides
RU2007103151A RU2413520C2 (ru) 2000-06-08 2001-06-07 Вакцинная композиция, содержащая иммуностимулирующие олигодезоксинуклеотиды
IS6627A IS1993B (is) 2000-06-08 2002-11-18 Ónæmisörvandi fádeoxýkirni
IL152959A IL152959A (en) 2000-06-08 2002-11-20 Use of oligodeoxynoliotoids that stimulate the immune system To prepare a pharmaceutical preparation that stimulates the immune system
ZA200209479A ZA200209479B (en) 2000-06-08 2002-11-21 Immunostimulatory oligodeoxynucleotides.
NO20025835A NO329492B1 (no) 2000-06-08 2002-12-04 Anvendelse av immunstimulerende oligodeoksynukleinsyremolekyler for fremstilling av immunstimulerende, farmasoytiske sammensetninger og farmasoytiske sammensetninger som inneholder de samme.
HK03109011A HK1056678A1 (en) 2000-06-08 2003-12-11 Immunostimulatory oligodeoxynucleotides
US11/609,777 US20070218073A1 (en) 2000-06-08 2006-12-12 Antigenic composition
JP2013002571A JP5908851B2 (ja) 2000-06-08 2013-01-10 免疫促進性オリゴデオキシヌクレオチド
US13/786,815 US8945591B2 (en) 2000-06-08 2013-03-06 Methods and compositions involving immunostimulatory oligodeoxynucleotides
US14/585,740 US9492537B2 (en) 2000-06-08 2014-12-30 Methods and compositions involving immunostimulatory oligodeoxynucleotides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0100000A AT410173B (de) 2000-06-08 2000-06-08 Antigene zusammensetzung

Publications (2)

Publication Number Publication Date
ATA10002000A true ATA10002000A (de) 2002-07-15
AT410173B AT410173B (de) 2003-02-25

Family

ID=3683921

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0100000A AT410173B (de) 2000-06-08 2000-06-08 Antigene zusammensetzung
AT01936440T ATE290880T1 (de) 2000-06-08 2001-06-07 Antigene zusammensetzung die ein polykationisches peptid und inosin und cytosin enthält

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01936440T ATE290880T1 (de) 2000-06-08 2001-06-07 Antigene zusammensetzung die ein polykationisches peptid und inosin und cytosin enthält

Country Status (7)

Country Link
US (2) US7148191B2 (de)
EP (1) EP1286695B1 (de)
AT (2) AT410173B (de)
AU (1) AU2001262345A1 (de)
DE (1) DE60109443T2 (de)
WO (1) WO2001093903A1 (de)
ZA (1) ZA200209479B (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ520200A (en) * 1999-12-22 2004-04-30 Aventis Pasteur Polynucleotides encoding the Clamydia pneumoniae polypeptides omp P6 precursor gene product
DE60100814T2 (de) 2000-06-08 2004-07-01 Intercell Biomedizinische Forschungs- Und Entwicklungs Gmbh Immunstimulierende oligodeoxynukleotide
AT410173B (de) * 2000-06-08 2003-02-25 Cistem Biotechnologies Gmbh Antigene zusammensetzung
ATE398175T1 (de) * 2000-12-08 2008-07-15 Coley Pharmaceuticals Gmbh Cpg-artige nukleinsäuren und verfahren zu ihrer verwendung
US20030036639A1 (en) * 2001-01-03 2003-02-20 Emery Daryll A. Immunizing compositions and methods of use
US7244438B2 (en) 2001-01-05 2007-07-17 Intercell Ag Uses for polycationic compounds
EP1347776A2 (de) * 2001-01-05 2003-10-01 Intercell Biomedizinische Forschungs- und Entwicklungs AG Gebrauch von polykationen als entzündungshemmende mittel
CA2452909A1 (en) * 2001-12-07 2003-06-13 Intercell Ag Immunostimulatory oligodeoxynucleotides
US8088388B2 (en) 2002-02-14 2012-01-03 United Biomedical, Inc. Stabilized synthetic immunogen delivery system
JP2005527506A (ja) * 2002-02-28 2005-09-15 インターツェル・アクチェンゲゼルシャフト リガンドｅ．ｇ．ｔ細胞エピトープの単離方法
AU2003243161A1 (en) * 2002-04-24 2003-11-10 The Regents Of The University Of California Methods for stimulating tlr/irf3 pathways for inducing anti-microbial, anti-inflammatory and anticancer responses
ATE535231T1 (de) * 2002-07-03 2011-12-15 Oncovir Inc Verfahren zur herstellung von poly-iclc und seine verwendung
JP2005533855A (ja) 2002-07-24 2005-11-10 インターツェル・アクチェンゲゼルシャフト 病原性ウイルスからの別のリーディングフレームによりコードされる抗原
EP2402026A3 (de) 2002-09-13 2012-04-18 Intercell AG Verfahren zum Isolieren von Hepatitis-C-Virus-Peptiden
AU2003274011B2 (en) 2002-10-15 2010-03-04 Intercell Ag Nucleic acids coding for adhesion factor of group B streptococcus, adhesion factors of group B streptococcus and further uses thereof
AU2003297317A1 (en) * 2002-12-13 2004-07-09 Case Western Reserve University Defensin-inducing peptides from fusobacterium
JP2006520202A (ja) 2003-03-04 2006-09-07 インターツェル・アクチェンゲゼルシャフト ストレプトコッカス・ピオゲネス抗原
ATE485056T1 (de) * 2003-03-24 2010-11-15 Intercell Ag Verbesserte impfstoffe
JP2006521321A (ja) * 2003-03-24 2006-09-21 インターツェル・アクチェンゲゼルシャフト 免疫応答を促進するためのミョウバンおよびＴｈ１免疫応答誘起アジュバントの使用
CA2520868A1 (en) 2003-03-31 2004-10-14 Intercell Ag Staphylococcus epidermidis antigens
EP2314719A1 (de) 2003-04-15 2011-04-27 Intercell AG S. pneumoniae Antigene
AU2004235952A1 (en) 2003-05-07 2004-11-18 Intercell Ag Streptococcus agalactiae antigens I + II
EP2327720A1 (de) 2003-05-30 2011-06-01 Intercell AG Enterokokken-Antigene
ATE520709T1 (de) * 2003-09-19 2011-09-15 Epitopix Llc Campylobacter-polypeptide und verwendungsverfahren
CA2583026A1 (en) * 2004-10-29 2006-05-04 Intercell Ag Hcv vaccines for chronic hcv patients
EP1853306B1 (de) * 2005-02-14 2016-06-15 Epitopix, LLC Polypeptide von staphylococcus aureus und methoden zu deren verwendung
RU2490024C2 (ru) 2006-06-28 2013-08-20 Статенс Серум Инститьют Расширение спектра т клеток для включения субдоминантных эпитопов путем вакцинации с антигенами, доставленными как белковые фрагменты или пептидные коктейли
JP2009542196A (ja) 2006-07-07 2009-12-03 インターセル アーゲー 小型の化膿連鎖球菌抗原およびそれらの使用
WO2008031133A2 (en) 2006-09-15 2008-03-20 Intercell Ag Borrelia antigens
EP1923069A1 (de) 2006-11-20 2008-05-21 Intercell AG Schutzpeptide gegen S. pneumoniae und diesbezügliche Zusammensetzungen, Verfahren und Verwendungen
EP2120984A2 (de) 2007-01-12 2009-11-25 Intercell AG Schützende proteine von s. agalactiae, kombinationen daraus und anwendungsverfahren dafür
KR20100051041A (ko) * 2007-03-07 2010-05-14 엔벤타 바이오파마슈티칼스 코퍼레이션 이중-가닥 봉쇄형 핵산 조성물
EP2497779A1 (de) 2007-05-02 2012-09-12 Intercell AG Klebsiella-Antigene
US20100203083A1 (en) 2007-05-31 2010-08-12 Medigene Ag Mutated structural protein of a parvovirus
EP2012122A1 (de) 2007-07-06 2009-01-07 Medigene AG Strukturproteine von mutierten Parvoviren als Impfstoffe
EP2511291A3 (de) 2007-06-18 2012-11-07 Intercell AG Chlamydia-Antigene
CN101827613A (zh) 2007-09-27 2010-09-08 免疫疫苗技术有限公司 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用
WO2009086640A1 (en) * 2008-01-10 2009-07-16 Nventa Biopharmaceuticals Corporation Adjuvant compositions comprising poly-ic and a cationic polymer
CN101977927A (zh) 2008-03-17 2011-02-16 英特塞尔股份公司 针对肺炎链球菌保护的肽以及与其有关的组合物、方法和用途
EP2296696B1 (de) 2008-06-05 2014-08-27 ImmunoVaccine Technologies Inc. Zusammensetzungen mit liposomen, einem antigen, einem polynucleotid und einem träger mit einer kontinuierlichen phase einer hydrophoben substanz
DK2310046T3 (da) 2008-06-27 2016-04-25 Zoetis Services Llc Hidtil ukendte adjuvanssammensætninger
US20130243779A1 (en) 2009-02-05 2013-09-19 Intercell Ag Peptides protective against e. faecalis, methods and uses relating thereto
WO2010092176A2 (en) 2009-02-13 2010-08-19 Intercell Ag Nontypable haemophilus influenzae antigens
NZ614557A (en) 2009-03-23 2015-03-27 Epitopix Llc Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use
EP2308896A1 (de) 2009-10-09 2011-04-13 Sanofi-aventis Polypeptides zum Binden an den Rezeptor für weiterentwickelte Glykierungsendprodukte sowie Zusammensetzungen und Verfahren, die diese Polypeptide beinhalten
AU2010305374A1 (en) 2009-10-09 2012-05-03 Sanofi Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same
EP2319871A1 (de) 2009-11-05 2011-05-11 Sanofi-aventis Polypeptide zum Binden an den Rezeptor für weiterentwickelte Glykierungsendprodukte sowie Zusammensetzungen und Verfahren, die diese Polypeptide beinhalten
PL2753352T5 (pl) 2010-09-03 2022-10-17 Valneva Austria Gmbh Izolowany polipeptyd białek toksyny a i toksyny b z c. difficile i jego zastosowania
AR082925A1 (es) 2010-09-08 2013-01-16 Medigene Ag Proteinas estructurales mutadas por parvovirus con epitopo de celulas b de proteccion cruzada, producto y metodos relacionados
WO2012139094A2 (en) 2011-04-08 2012-10-11 H. Lee Moffitt Cancer Center And Research Institute, Inc. Method of developing a vaccine using peptide-poly ic complexes
CA3005608C (en) 2013-09-19 2020-06-30 Zoetis Services Llc Water-in-oil emulsions comprising immunostimulatory oligonucleotides
KR20170097116A (ko) 2015-01-16 2017-08-25 조에티스 서비시즈 엘엘씨 구제역 백신
US10166280B2 (en) 2016-06-08 2019-01-01 Epitopix, Llc Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use
EP3752184A1 (de) 2018-02-16 2020-12-23 2A Pharma AB Parvovirus-strukturprotein zur behandlung von autoimmunerkrankungen
EP3527223A1 (de) 2018-02-16 2019-08-21 2A Pharma AB Mutiertes parvovirus-strukturprotein
WO2020234300A1 (en) 2019-05-20 2020-11-26 Valneva Se A subunit vaccine for treatment or prevention of a respiratory tract infection
US20220233672A1 (en) 2019-05-31 2022-07-28 Universidad De Chile An immunogenic formulation that induces protection against shiga toxin-producing escherichia coli (stec)
WO2022074061A1 (en) 2020-10-07 2022-04-14 Valneva Sweden Ab Cholera vaccine formulation
EP4319802A2 (de) 2021-04-09 2024-02-14 Valneva SE Kombinationsimpfstoff gegen menschliches metapneumovirus
WO2023083964A1 (en) 2021-11-11 2023-05-19 2A Pharma Ab Parvovirus structural protein against beta- and gamma-hpv
WO2023232901A1 (en) 2022-06-01 2023-12-07 Valneva Austria Gmbh Clostridium difficile vaccine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6801650D0 (pt) 1968-08-20 1973-03-07 R Maes Processo para preparacao de complexos geradores de interferon
US3725545A (en) * 1971-02-03 1973-04-03 R Maes Enhancement of antibody production by nucleic acid-polycation complexes
CO4600681A1 (es) 1996-02-24 1998-05-08 Boehringer Ingelheim Pharma Composicion farmaceutica para la modulacion inmunitaria
US6008334A (en) 1996-07-24 1999-12-28 The Board Of Regents Of The University Of Oklahoma Base-protected nucleotide analogs with protected thiol groups
AU2001267349A1 (en) * 2000-04-14 2001-10-30 Cistem Biotechnologies Gmbh Pharmaceutical preparations comprising modified peptides
AT410173B (de) * 2000-06-08 2003-02-25 Cistem Biotechnologies Gmbh Antigene zusammensetzung

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AU2001262345A1 (en) 2001-12-17
ZA200209479B (en) 2003-11-21
US20070218073A1 (en) 2007-09-20
US7148191B2 (en) 2006-12-12
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