AT380256B - Verfahren zur herstellung eines neuen (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-onderivats - Google Patents

Verfahren zur herstellung eines neuen (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-onderivats

Info

Publication number
AT380256B
AT380256B AT0319182A AT319182A AT380256B AT 380256 B AT380256 B AT 380256B AT 0319182 A AT0319182 A AT 0319182A AT 319182 A AT319182 A AT 319182A AT 380256 B AT380256 B AT 380256B
Authority
AT
Austria
Prior art keywords
oner
tetrazine
imidazo
derivative
producing
Prior art date
Application number
AT0319182A
Other languages
German (de)
English (en)
Other versions
ATA319182A (de
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of ATA319182A publication Critical patent/ATA319182A/de
Application granted granted Critical
Publication of AT380256B publication Critical patent/AT380256B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT0319182A 1981-08-24 1982-08-23 Verfahren zur herstellung eines neuen (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-onderivats AT380256B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
ATA319182A ATA319182A (de) 1985-09-15
AT380256B true AT380256B (de) 1986-05-12

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0319182A AT380256B (de) 1981-08-24 1982-08-23 Verfahren zur herstellung eines neuen (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-onderivats

Country Status (29)

Country Link
JP (1) JPS5843975A (fr)
KR (1) KR890000094B1 (fr)
AT (1) AT380256B (fr)
AU (1) AU571430B2 (fr)
BE (1) BE894175A (fr)
CA (1) CA1197247A (fr)
CH (1) CH655114A5 (fr)
DE (2) DE3231255A1 (fr)
DK (1) DK161147C (fr)
ES (1) ES8400438A1 (fr)
FI (1) FI73434C (fr)
FR (1) FR2511679A1 (fr)
GB (1) GB2104522B (fr)
GE (1) GEP19960641B (fr)
GR (1) GR76863B (fr)
HU (1) HU186107B (fr)
IE (1) IE53408B1 (fr)
IL (1) IL66606A (fr)
IT (1) IT1152505B (fr)
LT (1) LT2436B (fr)
LU (1) LU84347A1 (fr)
LV (2) LV5511A3 (fr)
NL (2) NL192739C (fr)
NZ (1) NZ201668A (fr)
OA (1) OA07174A (fr)
SE (1) SE448543B (fr)
SU (1) SU1447284A3 (fr)
UA (1) UA5971A1 (fr)
ZA (1) ZA826120B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
FR2531958B1 (fr) * 1982-08-17 1986-10-31 May & Baker Ltd Nouveaux derive
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP2275425A1 (fr) * 2003-12-30 2011-01-19 Chemagis Ltd. Nouvelles formes cristallines de temozolomide
JP5475235B2 (ja) 2005-01-21 2014-04-16 アステックス・セラピューティクス・リミテッド 医薬化合物
AR060635A1 (es) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
WO2008044045A1 (fr) 2006-10-12 2008-04-17 Astex Therapeutics Limited Combinaisons pharmaceutiques
CA2703489A1 (fr) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. Derive de dihydropyrazolopyrimidinone substitue par pyridone
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
EP2367828B1 (fr) * 2008-11-24 2014-06-11 Reliance Life Sciences Pvt., Ltd. Procédé de préparation de dérivés de tétrazine
EP2403339B1 (fr) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Thérapie de combinaison anti-cancer avec un inhibiteur de akt et d'autres agents anti-cancer
WO2010149968A1 (fr) 2009-06-23 2010-12-29 Pharminox Limited Composés 3h-imidazo[5,1-d][1,2,3,5-tétrazin-4-one 3-substitués-8-substitués et leur utilisation
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
IL261721B (en) 2016-03-15 2022-07-01 Oryzon Genomics Sa Combinations of lsd1 inhibitors for use in the treatment of solid tumors
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Also Published As

Publication number Publication date
GEP19960641B (en) 1996-11-15
FI822921A0 (fi) 1982-08-23
FI73434C (fi) 1987-10-09
DE3231255C2 (fr) 1992-02-27
GB2104522B (en) 1985-06-12
CA1197247A (fr) 1985-11-26
FR2511679A1 (fr) 1983-02-25
KR840001175A (ko) 1984-03-28
DK377882A (da) 1983-02-25
LT2436B (lt) 1994-02-15
IL66606A0 (en) 1982-12-31
HU186107B (en) 1985-06-28
BE894175A (fr) 1983-02-23
FI73434B (fi) 1987-06-30
IE822026L (en) 1983-02-24
GB2104522A (en) 1983-03-09
LV5511A3 (lv) 1994-03-10
CH655114A5 (fr) 1986-03-27
NL8203286A (nl) 1983-03-16
OA07174A (fr) 1984-04-30
AU571430B2 (en) 1988-04-21
UA5971A1 (uk) 1994-12-29
FR2511679B1 (fr) 1985-02-01
ATA319182A (de) 1985-09-15
GR76863B (fr) 1984-09-04
IE53408B1 (en) 1988-11-09
KR890000094B1 (ko) 1989-03-07
SE8204817L (sv) 1983-02-25
SE448543B (sv) 1987-03-02
JPH045029B2 (fr) 1992-01-30
DE19975037I2 (de) 2001-06-13
AU8749382A (en) 1983-03-03
LU84347A1 (fr) 1983-06-07
ES515176A0 (es) 1983-11-01
ES8400438A1 (es) 1983-11-01
SU1447284A3 (ru) 1988-12-23
IL66606A (en) 1987-07-31
FI822921L (fi) 1983-02-25
IT8222938A0 (it) 1982-08-23
ZA826120B (en) 1983-07-27
DK161147C (da) 1991-11-18
LV5621A3 (lv) 1994-05-10
NL990010I2 (nl) 1999-09-01
NZ201668A (en) 1985-08-16
IT1152505B (it) 1987-01-07
DE3231255A1 (de) 1983-03-03
NL192739C (nl) 1998-01-06
NL990010I1 (nl) 1999-07-01
DK161147B (da) 1991-06-03
NL192739B (nl) 1997-09-01
SE8204817D0 (sv) 1982-08-23
JPS5843975A (ja) 1983-03-14

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
EZF Grant of a certificate of protection

Free format text: SZ 26/1999, 19990618, EXPIRES:20080915

SZA Application filed for a certificate of protection

Free format text: SZ 26/1999, 19990618

ELA Expired due to lapse of time