AT368506B - Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen - Google Patents

Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen

Info

Publication number
AT368506B
AT368506B AT0091980A AT91980A AT368506B AT 368506 B AT368506 B AT 368506B AT 0091980 A AT0091980 A AT 0091980A AT 91980 A AT91980 A AT 91980A AT 368506 B AT368506 B AT 368506B
Authority
AT
Austria
Prior art keywords
salts
producing new
carbonic acids
penem
new penem
Prior art date
Application number
AT0091980A
Other languages
English (en)
Other versions
ATA91980A (de
Inventor
Maurizio Foglio
Giovanni Franceschi
Cosimo Scarafile
Federico Arcamone
Aurora Sanfilippo
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ATA91980A publication Critical patent/ATA91980A/de
Application granted granted Critical
Publication of AT368506B publication Critical patent/AT368506B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
AT0091980A 1979-02-24 1980-02-19 Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen AT368506B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7906634 1979-02-24
GB7932591 1979-09-20

Publications (2)

Publication Number Publication Date
ATA91980A ATA91980A (de) 1982-02-15
AT368506B true AT368506B (de) 1982-10-25

Family

ID=26270697

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0091980A AT368506B (de) 1979-02-24 1980-02-19 Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen

Country Status (24)

Country Link
AT (1) AT368506B (de)
AU (1) AU535080B2 (de)
CA (2) CA1154010A (de)
CH (2) CH654831A5 (de)
CS (1) CS226010B2 (de)
DE (1) DE3006273A1 (de)
DK (1) DK159448C (de)
ES (2) ES488886A0 (de)
FI (1) FI75163C (de)
FR (1) FR2449690B1 (de)
GB (1) GB2043639B (de)
GR (1) GR73623B (de)
HK (1) HK74487A (de)
HU (1) HU182664B (de)
IE (1) IE49407B1 (de)
IT (1) IT1193922B (de)
LU (1) LU82192A1 (de)
NL (1) NL192265C (de)
NO (1) NO161000C (de)
NZ (1) NZ192949A (de)
PT (1) PT70849A (de)
SE (1) SE449489B (de)
UA (1) UA6041A1 (de)
YU (1) YU42964B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
DE3121510A1 (de) * 1980-07-04 1982-06-16 Farmitalia Carlo Erba S.p.A., 20159 Milano 6-alkyl-2-subst.-peneme und verfahren zu ihrer herstellung
JPS588084A (ja) * 1981-07-08 1983-01-18 Takeda Chem Ind Ltd (6r)−置換−(5r)−ペネム−3−カルボン酸誘導体およびその製造法
EP0180252B1 (de) * 1981-07-15 1989-04-26 Sumitomo Pharmaceuticals Company, Limited Verfahren zur Herstellung von Azetidinonverbindungen
NL8204720A (nl) * 1981-12-11 1983-07-01 Erba Farmitalia Werkwijze voor het bereiden van optisch actieve penemverbindingen.
NO831160L (no) * 1982-04-08 1983-10-10 Erba Farmitalia Fremstilling av substituerte penem-derivater
PH21930A (en) * 1982-11-16 1988-04-08 Ciba Geigy Ag 6-hydroxy-lower alkylpenem compounds,pharmaceutical composition containing same and method of use thereof
DE3372968D1 (en) * 1982-11-16 1987-09-17 Ciba Geigy Ag Heterocyclyl-thio compounds, process for their preparation, pharmaceutical compositions containing them and their use
GB8300295D0 (en) * 1983-01-06 1983-02-09 Erba Farmitalia Penem esters
JPS59152387A (ja) * 1983-02-10 1984-08-31 Shionogi & Co Ltd 新規ペネム化合物
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
US4656165A (en) * 1983-09-02 1987-04-07 Ciba-Geigy Corporation Aminomethyl penem compounds
US4711886A (en) * 1984-07-02 1987-12-08 Merck & Co., Inc. β-lactam derivatives as anti-inflammatory and antidegenerative agents
US4761408A (en) * 1984-11-02 1988-08-02 Ciba-Geigy Corporation Crystalline aminomethyl compound
ES2058328T3 (es) * 1987-02-11 1994-11-01 Ciba Geigy Ag Acidos beta-lactama carboxilicos biciclicos.
US5364768A (en) * 1987-07-07 1994-11-15 Farmitalia Carlo Erba S.R.L. Process for the preparation of penems
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
IT1286558B1 (it) * 1996-02-27 1998-07-15 Menarini Farma Ind Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
JP3866298B2 (ja) 1997-12-29 2007-01-10 リサーチ コーポレイション テクノロジーズ,インコーポレイティド β−ラクタマーゼインヒビターとしての2β−置換化−6−アルキリデンペニシラン酸誘導体
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
CA2454413A1 (en) 2001-07-24 2003-03-13 Alamx, L.L.C. 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors
JP2005525399A (ja) 2002-04-04 2005-08-25 アラムクス エルエルシー セリンおよびメタロ−β−ラクタマーゼの阻害剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77306A1 (de) * 1977-05-09 1979-01-18
AU3796278A (en) * 1977-07-13 1980-01-17 Glaxo Group Ltd Penams and azetidinones
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
US4155912A (en) * 1977-12-14 1979-05-22 Bristol-Myers Company 2-Methylpenem-3-carboxylic acid antibiotics
JPS54117459A (en) * 1978-01-20 1979-09-12 Glaxo Group Ltd Novel lactam compound
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
EP0010358A1 (de) * 1978-09-20 1980-04-30 Glaxo Group Limited Beta-Lactam-Verbindungen, Verfahren zu ihrer Herstellung, sie enthaltende Präparate, bei ihrer Herstellung verwendbare Zwischenverbindungen und Verfahren zu deren Herstellung
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
EP0013067A1 (de) * 1978-12-22 1980-07-09 Beecham Group Plc Bicyclische beta-Lactam antibakterielle Mittel, ihre Verwendung in pharmazeutischen Zusammensetzungen, Verfahren zu ihrer Herstellung und Zwischenprodukte zur Verwendung in solchen Verfahren

Also Published As

Publication number Publication date
YU46180A (en) 1983-02-28
FI800493A (fi) 1980-08-25
FI75163B (fi) 1988-01-29
ES8107224A1 (es) 1981-10-01
AU535080B2 (en) 1984-03-01
NO161000C (no) 1989-06-21
LU82192A1 (fr) 1980-06-06
ES8200685A1 (es) 1981-11-16
NO800501L (no) 1980-08-25
ES495977A0 (es) 1981-10-01
YU42964B (en) 1989-02-28
NL192265C (nl) 1997-04-03
NO161000B (no) 1989-03-13
HK74487A (en) 1987-10-23
PT70849A (en) 1980-03-01
IE800338L (en) 1980-08-24
AU5567080A (en) 1980-09-11
GB2043639B (en) 1983-07-20
DK159448B (da) 1990-10-15
SE8001424L (sv) 1980-08-25
HU182664B (en) 1984-02-28
GB2043639A (en) 1980-10-08
FR2449690B1 (fr) 1986-06-13
DK159448C (da) 1991-03-04
CA1154010A (en) 1983-09-20
CA1212665B (en) 1986-10-14
ES488886A0 (es) 1981-11-16
IT8020021A1 (it) 1981-08-19
NL8001012A (nl) 1980-08-26
DE3006273A1 (de) 1980-09-04
DK77580A (da) 1980-08-25
IE49407B1 (en) 1985-10-02
NL192265B (nl) 1996-12-02
FR2449690A1 (fr) 1980-09-19
CH654831A5 (de) 1986-03-14
SE449489B (sv) 1987-05-04
ATA91980A (de) 1982-02-15
GR73623B (de) 1984-03-26
IT1193922B (it) 1988-08-31
CS226010B2 (en) 1984-03-19
UA6041A1 (uk) 1994-12-29
CH651570A5 (de) 1985-09-30
FI75163C (fi) 1988-05-09
IT8020021A0 (it) 1980-02-19
NZ192949A (en) 1984-03-16

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties
ELJ Ceased due to non-payment of the annual fee