IT1286558B1 - Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici - Google Patents

Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici

Info

Publication number
IT1286558B1
IT1286558B1 IT96FI000033A ITFI960033A IT1286558B1 IT 1286558 B1 IT1286558 B1 IT 1286558B1 IT 96FI000033 A IT96FI000033 A IT 96FI000033A IT FI960033 A ITFI960033 A IT FI960033A IT 1286558 B1 IT1286558 B1 IT 1286558B1
Authority
IT
Italy
Prior art keywords
penems
preparation
halogenomethyl
antibacterial
antibacterial penems
Prior art date
Application number
IT96FI000033A
Other languages
English (en)
Inventor
Enzo Perrotta
Maria Altamura
Original Assignee
Menarini Farma Ind
Luso Farmaco Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Farma Ind, Luso Farmaco Inst filed Critical Menarini Farma Ind
Publication of ITFI960033A0 publication Critical patent/ITFI960033A0/it
Priority to IT96FI000033A priority Critical patent/IT1286558B1/it
Priority to CA002247269A priority patent/CA2247269A1/en
Priority to RU98117732/04A priority patent/RU2175971C2/ru
Priority to EP97903325A priority patent/EP0883620B1/en
Priority to DE69715158T priority patent/DE69715158T2/de
Priority to AU17923/97A priority patent/AU1792397A/en
Priority to PL97328435A priority patent/PL328435A1/xx
Priority to PCT/EP1997/000783 priority patent/WO1997031922A1/en
Priority to ES97903325T priority patent/ES2180926T3/es
Priority to CN97192589A priority patent/CN1116298C/zh
Priority to ZA9701471A priority patent/ZA971471B/xx
Publication of ITFI960033A1 publication Critical patent/ITFI960033A1/it
Application granted granted Critical
Publication of IT1286558B1 publication Critical patent/IT1286558B1/it
Priority to US09/130,264 priority patent/US6153747A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT96FI000033A 1996-02-27 1996-02-27 Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici IT1286558B1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT96FI000033A IT1286558B1 (it) 1996-02-27 1996-02-27 Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
PL97328435A PL328435A1 (en) 1996-02-27 1997-02-19 Method of obtaining 2-halophenylpenemes and antibacterial compounds obtained thereby
ES97903325T ES2180926T3 (es) 1996-02-27 1997-02-19 Procedimiento para la preparacion de 2-halometil-penem y su uso en la preparacion de penem antibacterianos.
EP97903325A EP0883620B1 (en) 1996-02-27 1997-02-19 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems
DE69715158T DE69715158T2 (de) 1996-02-27 1997-02-19 Verfahren zur herstellung von 2-halomethyl-penemen und ihre verwendung zur herstellung von antibakteriellen penemen
AU17923/97A AU1792397A (en) 1996-02-27 1997-02-19 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems
CA002247269A CA2247269A1 (en) 1996-02-27 1997-02-19 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems
PCT/EP1997/000783 WO1997031922A1 (en) 1996-02-27 1997-02-19 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems
RU98117732/04A RU2175971C2 (ru) 1996-02-27 1997-02-19 Способ получения 2-галогенметилпенемов и производные 2-азетидинона в качестве промежуточных соединений
CN97192589A CN1116298C (zh) 1996-02-27 1997-02-19 制备2－卤甲基－青霉烯的方法及其在制备抗菌青霉烯中的应用
ZA9701471A ZA971471B (en) 1996-02-27 1997-02-20 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems.
US09/130,264 US6153747A (en) 1996-02-27 1998-08-06 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96FI000033A IT1286558B1 (it) 1996-02-27 1996-02-27 Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici

Publications (3)

Publication Number Publication Date
ITFI960033A0 ITFI960033A0 (it) 1996-02-27
ITFI960033A1 ITFI960033A1 (it) 1997-08-27
IT1286558B1 true IT1286558B1 (it) 1998-07-15

Family

ID=11351505

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96FI000033A IT1286558B1 (it) 1996-02-27 1996-02-27 Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici

Country Status (12)

Country Link
US (1) US6153747A (it)
EP (1) EP0883620B1 (it)
CN (1) CN1116298C (it)
AU (1) AU1792397A (it)
CA (1) CA2247269A1 (it)
DE (1) DE69715158T2 (it)
ES (1) ES2180926T3 (it)
IT (1) IT1286558B1 (it)
PL (1) PL328435A1 (it)
RU (1) RU2175971C2 (it)
WO (1) WO1997031922A1 (it)
ZA (1) ZA971471B (it)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT368506B (de) * 1979-02-24 1982-10-25 Erba Farmitalia Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen
GB2118181B (en) * 1982-04-08 1986-07-30 Erba Farmitalia Substituted penem derivatives and new process for their preparation
US4794109A (en) * 1982-11-16 1988-12-27 Ciba-Geigy Corporation 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter
JPS59152387A (ja) * 1983-02-10 1984-08-31 Shionogi & Co Ltd 新規ペネム化合物
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
GB9110507D0 (en) * 1991-05-15 1991-07-03 Smithkline Beecham Plc Chemical compounds

Also Published As

Publication number Publication date
EP0883620B1 (en) 2002-09-04
CN1211988A (zh) 1999-03-24
ITFI960033A0 (it) 1996-02-27
DE69715158D1 (de) 2002-10-10
ITFI960033A1 (it) 1997-08-27
PL328435A1 (en) 1999-02-01
CA2247269A1 (en) 1997-09-04
CN1116298C (zh) 2003-07-30
AU1792397A (en) 1997-09-16
WO1997031922A1 (en) 1997-09-04
EP0883620A1 (en) 1998-12-16
US6153747A (en) 2000-11-28
RU2175971C2 (ru) 2001-11-20
ZA971471B (en) 1997-09-04
ES2180926T3 (es) 2003-02-16
DE69715158T2 (de) 2003-05-15

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Legal Events

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0001 Granted