DE69715158D1 - Verfahren zur herstellung von 2-halomethyl-penemen und ihre verwendung zur herstellung von antibakteriellen penemen - Google Patents

Verfahren zur herstellung von 2-halomethyl-penemen und ihre verwendung zur herstellung von antibakteriellen penemen

Info

Publication number
DE69715158D1
DE69715158D1 DE69715158T DE69715158T DE69715158D1 DE 69715158 D1 DE69715158 D1 DE 69715158D1 DE 69715158 T DE69715158 T DE 69715158T DE 69715158 T DE69715158 T DE 69715158T DE 69715158 D1 DE69715158 D1 DE 69715158D1
Authority
DE
Germany
Prior art keywords
penemes
producing
halomethyl
antibacterial
producing antibacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69715158T
Other languages
English (en)
Other versions
DE69715158T2 (de
Inventor
Enzo Perrotta
Maria Altamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Luso Farmaco dItalia SpA
Menarini Industrie Farmaceutiche Riunite SRL
Original Assignee
Istituto Luso Farmaco dItalia SpA
Menarini Industrie Farmaceutiche Riunite SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Luso Farmaco dItalia SpA, Menarini Industrie Farmaceutiche Riunite SRL filed Critical Istituto Luso Farmaco dItalia SpA
Publication of DE69715158D1 publication Critical patent/DE69715158D1/de
Application granted granted Critical
Publication of DE69715158T2 publication Critical patent/DE69715158T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69715158T 1996-02-27 1997-02-19 Verfahren zur herstellung von 2-halomethyl-penemen und ihre verwendung zur herstellung von antibakteriellen penemen Expired - Fee Related DE69715158T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96FI000033A IT1286558B1 (it) 1996-02-27 1996-02-27 Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
PCT/EP1997/000783 WO1997031922A1 (en) 1996-02-27 1997-02-19 Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems

Publications (2)

Publication Number Publication Date
DE69715158D1 true DE69715158D1 (de) 2002-10-10
DE69715158T2 DE69715158T2 (de) 2003-05-15

Family

ID=11351505

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69715158T Expired - Fee Related DE69715158T2 (de) 1996-02-27 1997-02-19 Verfahren zur herstellung von 2-halomethyl-penemen und ihre verwendung zur herstellung von antibakteriellen penemen

Country Status (12)

Country Link
US (1) US6153747A (de)
EP (1) EP0883620B1 (de)
CN (1) CN1116298C (de)
AU (1) AU1792397A (de)
CA (1) CA2247269A1 (de)
DE (1) DE69715158T2 (de)
ES (1) ES2180926T3 (de)
IT (1) IT1286558B1 (de)
PL (1) PL328435A1 (de)
RU (1) RU2175971C2 (de)
WO (1) WO1997031922A1 (de)
ZA (1) ZA971471B (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT368506B (de) * 1979-02-24 1982-10-25 Erba Farmitalia Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen
GB2118181B (en) * 1982-04-08 1986-07-30 Erba Farmitalia Substituted penem derivatives and new process for their preparation
US4794109A (en) * 1982-11-16 1988-12-27 Ciba-Geigy Corporation 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter
JPS59152387A (ja) * 1983-02-10 1984-08-31 Shionogi & Co Ltd 新規ペネム化合物
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
GB9110507D0 (en) * 1991-05-15 1991-07-03 Smithkline Beecham Plc Chemical compounds

Also Published As

Publication number Publication date
PL328435A1 (en) 1999-02-01
ITFI960033A1 (it) 1997-08-27
CA2247269A1 (en) 1997-09-04
CN1116298C (zh) 2003-07-30
CN1211988A (zh) 1999-03-24
ES2180926T3 (es) 2003-02-16
ITFI960033A0 (it) 1996-02-27
ZA971471B (en) 1997-09-04
RU2175971C2 (ru) 2001-11-20
EP0883620B1 (de) 2002-09-04
WO1997031922A1 (en) 1997-09-04
US6153747A (en) 2000-11-28
EP0883620A1 (de) 1998-12-16
IT1286558B1 (it) 1998-07-15
DE69715158T2 (de) 2003-05-15
AU1792397A (en) 1997-09-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee