NO161000C - Analogifremgangsmaate for fremstilling av en terapeutisk aktiv penemkarboksylsyre eller -ester. - Google Patents

Analogifremgangsmaate for fremstilling av en terapeutisk aktiv penemkarboksylsyre eller -ester.

Info

Publication number
NO161000C
NO161000C NO800501A NO800501A NO161000C NO 161000 C NO161000 C NO 161000C NO 800501 A NO800501 A NO 800501A NO 800501 A NO800501 A NO 800501A NO 161000 C NO161000 C NO 161000C
Authority
NO
Norway
Prior art keywords
penemkarboxylic
ester
preparing
acid
therapeutic active
Prior art date
Application number
NO800501A
Other languages
English (en)
Other versions
NO800501L (no
NO161000B (no
Inventor
Maurizio Foglio
Giovanni Franceschi
Cosimo Scarafile
Federico Arcamone
Aurora Sanfilippo
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of NO800501L publication Critical patent/NO800501L/no
Publication of NO161000B publication Critical patent/NO161000B/no
Publication of NO161000C publication Critical patent/NO161000C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
NO800501A 1979-02-24 1980-02-22 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv penemkarboksylsyre eller -ester. NO161000C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7906634 1979-02-24
GB7932591 1979-09-20

Publications (3)

Publication Number Publication Date
NO800501L NO800501L (no) 1980-08-25
NO161000B NO161000B (no) 1989-03-13
NO161000C true NO161000C (no) 1989-06-21

Family

ID=26270697

Family Applications (1)

Application Number Title Priority Date Filing Date
NO800501A NO161000C (no) 1979-02-24 1980-02-22 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv penemkarboksylsyre eller -ester.

Country Status (24)

Country Link
AT (1) AT368506B (no)
AU (1) AU535080B2 (no)
CA (2) CA1154010A (no)
CH (2) CH654831A5 (no)
CS (1) CS226010B2 (no)
DE (1) DE3006273A1 (no)
DK (1) DK159448C (no)
ES (2) ES8200685A1 (no)
FI (1) FI75163C (no)
FR (1) FR2449690B1 (no)
GB (1) GB2043639B (no)
GR (1) GR73623B (no)
HK (1) HK74487A (no)
HU (1) HU182664B (no)
IE (1) IE49407B1 (no)
IT (1) IT1193922B (no)
LU (1) LU82192A1 (no)
NL (1) NL192265C (no)
NO (1) NO161000C (no)
NZ (1) NZ192949A (no)
PT (1) PT70849A (no)
SE (1) SE449489B (no)
UA (1) UA6041A1 (no)
YU (1) YU42964B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
DE3121510A1 (de) * 1980-07-04 1982-06-16 Farmitalia Carlo Erba S.p.A., 20159 Milano 6-alkyl-2-subst.-peneme und verfahren zu ihrer herstellung
JPS588084A (ja) * 1981-07-08 1983-01-18 Takeda Chem Ind Ltd （６ｒ）−置換−（５ｒ）−ペネム−３−カルボン酸誘導体およびその製造法
EP0070204B1 (en) * 1981-07-15 1987-11-19 Sumitomo Pharmaceuticals Company, Limited Carboxylic beta-lactam compounds and the preparation thereof
US4508649A (en) * 1981-12-11 1985-04-02 Farmitalia Carlo Erba Process for preparing optically active penems
NO831160L (no) * 1982-04-08 1983-10-10 Erba Farmitalia Fremstilling av substituerte penem-derivater
PH21930A (en) * 1982-11-16 1988-04-08 Ciba Geigy Ag 6-hydroxy-lower alkylpenem compounds,pharmaceutical composition containing same and method of use thereof
DE3372968D1 (en) * 1982-11-16 1987-09-17 Ciba Geigy Ag Heterocyclyl-thio compounds, process for their preparation, pharmaceutical compositions containing them and their use
GB8300295D0 (en) * 1983-01-06 1983-02-09 Erba Farmitalia Penem esters
JPS59152387A (ja) * 1983-02-10 1984-08-31 Shionogi & Co Ltd 新規ペネム化合物
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
US4656165A (en) * 1983-09-02 1987-04-07 Ciba-Geigy Corporation Aminomethyl penem compounds
US4711886A (en) * 1984-07-02 1987-12-08 Merck & Co., Inc. β-lactam derivatives as anti-inflammatory and antidegenerative agents
US4761408A (en) * 1984-11-02 1988-08-02 Ciba-Geigy Corporation Crystalline aminomethyl compound
DE3882730D1 (de) * 1987-02-11 1993-09-09 Ciba Geigy Ag Bicyclische beta-lactam-carbonsaeuren.
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
US5364768A (en) * 1987-07-07 1994-11-15 Farmitalia Carlo Erba S.R.L. Process for the preparation of penems
IT1286558B1 (it) * 1996-02-27 1998-07-15 Menarini Farma Ind Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
DE69805975T2 (de) 1997-12-29 2002-12-19 Res Corp Technologies Inc 2-beta-substituierte-6-alkylidenpenizillansäure-derivate als beta-laktamase inhibitoren
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
US6720445B2 (en) * 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
CA2454413A1 (en) 2001-07-24 2003-03-13 Alamx, L.L.C. 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors
JP2005525399A (ja) 2002-04-04 2005-08-25 アラムクス エルエルシー セリンおよびメタロ−β−ラクタマーゼの阻害剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77306A1 (no) * 1977-05-09 1979-01-18
EP0000636A1 (en) * 1977-07-13 1979-02-07 Glaxo Group Limited Penem compounds, processes for their preparation, their use in pharmaceutical compositions and azetidinones used in their preparation
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
US4155912A (en) * 1977-12-14 1979-05-22 Bristol-Myers Company 2-Methylpenem-3-carboxylic acid antibiotics
JPS54117459A (en) * 1978-01-20 1979-09-12 Glaxo Group Ltd Novel lactam compound
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
JPS5559193A (en) * 1978-09-20 1980-05-02 Glaxo Group Ltd Bblactam compound
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
EP0013067A1 (en) * 1978-12-22 1980-07-09 Beecham Group Plc Bicyclic beta-lactam antibacterial agents, their use in pharmaceutical compositions, processes for their preparation and intermediates for use in such processes

Also Published As

Publication number Publication date
HU182664B (en) 1984-02-28
CH654831A5 (de) 1986-03-14
IE49407B1 (en) 1985-10-02
PT70849A (en) 1980-03-01
HK74487A (en) 1987-10-23
NL192265C (nl) 1997-04-03
UA6041A1 (uk) 1994-12-29
DK77580A (da) 1980-08-25
GR73623B (no) 1984-03-26
FR2449690A1 (fr) 1980-09-19
CS226010B2 (en) 1984-03-19
AU535080B2 (en) 1984-03-01
AU5567080A (en) 1980-09-11
NZ192949A (en) 1984-03-16
GB2043639B (en) 1983-07-20
CH651570A5 (de) 1985-09-30
ES488886A0 (es) 1981-11-16
SE8001424L (sv) 1980-08-25
FI75163C (fi) 1988-05-09
DK159448C (da) 1991-03-04
FI800493A (fi) 1980-08-25
NL192265B (nl) 1996-12-02
CA1154010A (en) 1983-09-20
IT8020021A0 (it) 1980-02-19
ATA91980A (de) 1982-02-15
CA1212665B (en) 1986-10-14
IT8020021A1 (it) 1981-08-19
DK159448B (da) 1990-10-15
GB2043639A (en) 1980-10-08
LU82192A1 (fr) 1980-06-06
ES8107224A1 (es) 1981-10-01
FI75163B (fi) 1988-01-29
NO800501L (no) 1980-08-25
SE449489B (sv) 1987-05-04
ES495977A0 (es) 1981-10-01
ES8200685A1 (es) 1981-11-16
AT368506B (de) 1982-10-25
DE3006273A1 (de) 1980-09-04
NL8001012A (nl) 1980-08-26
FR2449690B1 (fr) 1986-06-13
IT1193922B (it) 1988-08-31
NO161000B (no) 1989-03-13
YU42964B (en) 1989-02-28
YU46180A (en) 1983-02-28
IE800338L (en) 1980-08-24

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