AT345999B - Verfahren zur herstellung von neuen 15- substituierten omega-pentanorprostaglandinen - Google Patents

Verfahren zur herstellung von neuen 15- substituierten omega-pentanorprostaglandinen

Info

Publication number
AT345999B
AT345999B AT941073A AT941073A AT345999B AT 345999 B AT345999 B AT 345999B AT 941073 A AT941073 A AT 941073A AT 941073 A AT941073 A AT 941073A AT 345999 B AT345999 B AT 345999B
Authority
AT
Austria
Prior art keywords
pentanor
prostaglandine
producing new
substituted omega
omega
Prior art date
Application number
AT941073A
Other languages
German (de)
English (en)
Other versions
ATA941073A (de
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to AT521876A priority Critical patent/AT352754B/de
Publication of ATA941073A publication Critical patent/ATA941073A/de
Application granted granted Critical
Publication of AT345999B publication Critical patent/AT345999B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/30Compounds having groups
    • C07C43/315Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30Unsaturated compounds
    • C07C62/34Unsaturated compounds containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018Esters of cycloaliphatic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT941073A 1972-11-08 1973-11-08 Verfahren zur herstellung von neuen 15- substituierten omega-pentanorprostaglandinen AT345999B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT521876A AT352754B (de) 1972-11-08 1976-07-15 Verfahren zur herstellung von neuen ketophos- phonaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30475072A 1972-11-08 1972-11-08

Publications (2)

Publication Number Publication Date
ATA941073A ATA941073A (de) 1978-02-15
AT345999B true AT345999B (de) 1978-10-10

Family

ID=23177829

Family Applications (1)

Application Number Title Priority Date Filing Date
AT941073A AT345999B (de) 1972-11-08 1973-11-08 Verfahren zur herstellung von neuen 15- substituierten omega-pentanorprostaglandinen

Country Status (20)

Country Link
JP (1) JPS5714347B2 (da)
AT (1) AT345999B (da)
BE (1) BE807046A (da)
CA (1) CA1033727A (da)
CH (1) CH593930A5 (da)
DE (1) DE2355731C3 (da)
DK (1) DK143499C (da)
ES (3) ES420386A1 (da)
FI (1) FI58912C (da)
FR (3) FR2205338B1 (da)
GB (1) GB1456838A (da)
IE (1) IE40043B1 (da)
IL (2) IL50310A (da)
IN (1) IN139265B (da)
NL (1) NL7315307A (da)
NO (2) NO143663C (da)
PH (2) PH13261A (da)
SE (4) SE412229B (da)
SU (2) SU667131A3 (da)
ZA (1) ZA738595B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
JPS5823393B2 (ja) * 1974-03-14 1983-05-14 オノヤクヒンコウギヨウ カブシキガイシヤ プロスタグランジンルイジカゴウブツ ノ セイゾウホウホウ
US4028396A (en) * 1975-07-02 1977-06-07 American Cyanamid Company 16,16-Spirocycloalkyl prostaglandin derivatives
NZ183136A (en) * 1976-02-11 1978-11-13 Miles Lab Monospiroalkyl derivatives of prostaclandis and pharmaceutical compositions
US4074063A (en) * 1976-02-11 1978-02-14 Miles Laboratories, Inc. Bicycloalkyl derivatives of prostaglandins
US4404372A (en) * 1977-06-13 1983-09-13 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandin derivatives
DE2753995A1 (de) * 1977-12-03 1979-06-07 Bayer Ag Neue bicycloalkenyl-prostaglandine und verfahren zu ihrer herstellung
TR200000671T2 (tr) * 1997-09-09 2000-07-21 The Procter & Gamble Company FP agonistleri olarak yararlı aromatik C16-C20-ikameli tetrahidro prostaglandinler.
SK3382000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders
SK3362000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound analogous to prostaglandin f and use thereof
NZ513825A (en) 1999-03-05 2001-09-28 Procter & Gamble C 16 unsaturated FP-selective prostaglandins analogs
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
DE502007000840D1 (de) * 2007-11-28 2009-07-16 Bauer Maschinen Gmbh Winde
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20230097470A1 (en) * 2021-08-23 2023-03-30 Chirogate International Inc. Processes and intermediates for the preparations of carboprost and carboprost tromethamine, and carboprost tromethamine prepared therefrom

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4864073A (da) * 1971-04-30 1973-09-05

Also Published As

Publication number Publication date
ES444398A1 (es) 1977-12-01
FR2205338B1 (da) 1978-07-13
FI58912B (fi) 1981-01-30
FR2286147A1 (fr) 1976-04-23
FR2205338A1 (da) 1974-05-31
CA1033727A (en) 1978-06-27
IN139265B (da) 1976-05-29
AU6230273A (en) 1975-05-08
NO143663C (no) 1981-03-25
NO144385C (no) 1981-08-19
IE40043B1 (en) 1979-02-28
SE7612262L (sv) 1976-11-03
CH593930A5 (da) 1977-12-30
IL43571A0 (en) 1974-03-14
DE2355731B2 (de) 1980-04-30
JPS49133357A (da) 1974-12-21
PH13320A (en) 1980-03-13
SU667131A3 (ru) 1979-06-05
PH13261A (en) 1980-02-25
ES456279A1 (es) 1978-11-01
FR2286147B1 (da) 1978-09-22
SE417957B (sv) 1981-04-27
IL50310A (en) 1977-08-31
BE807046A (fr) 1974-05-08
NO743616L (no) 1974-05-09
FR2291200B1 (da) 1979-01-05
IL43571A (en) 1977-08-31
NO144385B (no) 1981-05-11
FR2291200A1 (fr) 1976-06-11
DK143499B (da) 1981-08-31
NO143663B (no) 1980-12-15
FI58912C (fi) 1981-05-11
DE2355731C3 (de) 1981-01-15
SE7612261L (sv) 1976-11-03
ES420386A1 (es) 1976-07-01
DK143499C (da) 1982-01-11
IE40043L (en) 1974-05-08
DE2355731A1 (de) 1974-05-22
ZA738595B (en) 1974-09-25
SE412229B (sv) 1980-02-25
SE7701523L (sv) 1977-02-10
SU704456A3 (ru) 1979-12-15
GB1456838A (en) 1976-11-24
NL7315307A (da) 1974-05-10
ATA941073A (de) 1978-02-15
JPS5714347B2 (da) 1982-03-24

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