AT367033B - Verfahren zur herstellung von neuen prostaglandinen - Google Patents

Verfahren zur herstellung von neuen prostaglandinen

Info

Publication number
AT367033B
AT367033B AT0620773A AT620773A AT367033B AT 367033 B AT367033 B AT 367033B AT 0620773 A AT0620773 A AT 0620773A AT 620773 A AT620773 A AT 620773A AT 367033 B AT367033 B AT 367033B
Authority
AT
Austria
Prior art keywords
prostaglandines
producing new
producing
new
new prostaglandines
Prior art date
Application number
AT0620773A
Other languages
English (en)
Other versions
ATA620773A (de
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to AT987676A priority Critical patent/AT359659B/de
Priority to AT987276A priority patent/AT366060B/de
Publication of ATA620773A publication Critical patent/ATA620773A/de
Application granted granted Critical
Publication of AT367033B publication Critical patent/AT367033B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
    • C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B2211/00—Applications
    • B63B2211/02—Oceanography
AT0620773A 1972-07-13 1973-07-13 Verfahren zur herstellung von neuen prostaglandinen AT367033B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT987676A AT359659B (de) 1972-07-13 1973-07-13 Verfahren zur herstellung eines neuen cyclopentanderivats
AT987276A AT366060B (de) 1972-07-13 1976-12-30 Verfahren zur herstellung von neuen 2-oxophenyl- alkylphosphonsaeuredimethylestern

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27122072A 1972-07-13 1972-07-13

Publications (2)

Publication Number Publication Date
ATA620773A ATA620773A (de) 1981-10-15
AT367033B true AT367033B (de) 1982-05-25

Family

ID=23034697

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0620773A AT367033B (de) 1972-07-13 1973-07-13 Verfahren zur herstellung von neuen prostaglandinen

Country Status (25)

Country Link
JP (4) JPS5241257B2 (de)
AR (2) AR209064A1 (de)
AT (1) AT367033B (de)
BE (1) BE802231A (de)
CA (1) CA1041495A (de)
CH (1) CH593254A5 (de)
CS (1) CS201027B2 (de)
DD (2) DD116459A5 (de)
DE (1) DE2334945A1 (de)
ES (4) ES416865A1 (de)
FI (1) FI57583C (de)
FR (1) FR2192834B1 (de)
GB (1) GB1446341A (de)
HU (4) HU171156B (de)
IE (1) IE37909B1 (de)
IL (2) IL42691A (de)
IN (1) IN138789B (de)
LU (1) LU68015A1 (de)
NL (1) NL7309792A (de)
NO (2) NO143741C (de)
PH (1) PH11461A (de)
SE (3) SE7705946L (de)
SU (4) SU644384A3 (de)
YU (1) YU187773A (de)
ZA (1) ZA734769B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
DE2463432C2 (de) * 1974-04-03 1987-06-19 Hoechst Ag, 6230 Frankfurt, De
DE2416193C2 (de) 1974-04-03 1985-08-14 Hoechst Ag, 6230 Frankfurt Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel
ZA747723B (en) * 1974-12-11 1976-11-24 Pfizer 11-desoxy-15-substituted-omega-pentanor prostaglandins
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
GB8329559D0 (en) * 1983-11-04 1983-12-07 Erba Farmitalia Furyl derivatives of 16-substituted prostaglandins preparations
SE9002596D0 (sv) * 1990-08-08 1990-08-08 Pharmacia Ab A method for synthesis of prostaglandin derivatives
US5972991A (en) * 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US6602900B2 (en) 1992-09-21 2003-08-05 Allergan, Inc. Cyclopentane heptan(ENE)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
KR100578616B1 (ko) * 2004-07-23 2006-05-10 한미약품 주식회사 Ｄ-에리트로-2,2-다이플루오로-2-데옥시-1-옥소라이보스화합물의 제조방법
US9353079B2 (en) * 2013-12-13 2016-05-31 Allergan, Inc. Solid forms of an alpha, omega di-substituted dihydroxy cyclopentyl compound and methods for the preparation and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
IL50311A (en) * 1972-06-02 1977-08-31 Pfizer Dimethyl alkoxy-2-oxoalkyl phosphonates and their preparattion

Also Published As

Publication number Publication date
IE37909L (en) 1974-01-13
SE7705946L (sv) 1977-05-20
ZA734769B (en) 1974-06-26
HU171946B (hu) 1978-04-28
NL7309792A (de) 1974-01-15
JPS52122349A (en) 1977-10-14
HU172058B (hu) 1978-05-28
JPS5241257B2 (de) 1977-10-17
ES437039A1 (es) 1977-01-01
SU644384A3 (ru) 1979-01-25
HU171156B (hu) 1977-11-28
BE802231A (fr) 1974-01-14
GB1446341A (en) 1976-08-18
NO743492L (no) 1974-01-15
HU171158B (hu) 1977-11-28
FR2192834A1 (de) 1974-02-15
CA1041495A (en) 1978-10-31
YU187773A (en) 1982-02-25
ATA620773A (de) 1981-10-15
DD116459A5 (de) 1975-11-20
IE37909B1 (en) 1977-11-09
NO143741B (no) 1980-12-29
JPS5297958A (en) 1977-08-17
SU584791A3 (ru) 1977-12-15
SU645563A3 (ru) 1979-01-30
PH11461A (en) 1978-02-01
JPS4992053A (de) 1974-09-03
LU68015A1 (de) 1974-01-21
NO144830B (no) 1981-08-10
CS201027B2 (en) 1980-10-31
ES437038A1 (es) 1977-01-01
IL42691A (en) 1979-07-25
SE7705945L (sv) 1977-05-20
SE7705947L (sv) 1977-05-20
IN138789B (de) 1976-04-03
JPS5293753A (en) 1977-08-06
FR2192834B1 (de) 1979-04-06
ES416865A1 (es) 1976-03-01
AR209064A1 (es) 1977-03-31
ES437037A1 (es) 1977-01-01
DE2334945A1 (de) 1974-03-07
SU645564A3 (ru) 1979-01-30
AU5778473A (en) 1975-01-09
FI57583B (fi) 1980-05-30
IL42691A0 (en) 1973-10-25
CH593254A5 (de) 1977-11-30
NO143741C (no) 1981-04-08
AR214383A1 (es) 1979-06-15
DD109210A5 (de) 1974-10-20
IL50308A0 (en) 1976-10-31
NO144830C (no) 1981-11-18
FI57583C (fi) 1980-09-10

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Legal Events

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ELJ Ceased due to non-payment of the annual fee