JPS5297958A - Production of intermediate of 155substituteddomegaa pentanoprostaglandine - Google Patents

Production of intermediate of 155substituteddomegaa pentanoprostaglandine

Info

Publication number
JPS5297958A
JPS5297958A JP14060576A JP14060576A JPS5297958A JP S5297958 A JPS5297958 A JP S5297958A JP 14060576 A JP14060576 A JP 14060576A JP 14060576 A JP14060576 A JP 14060576A JP S5297958 A JPS5297958 A JP S5297958A
Authority
JP
Japan
Prior art keywords
pentanoprostaglandine
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14060576A
Other languages
Japanese (ja)
Inventor
Rosu Jiyonson Maikeru
Yurugen Erunsuto Hesu Hansu
Ken Shiyaafu Toomasu
Shinfu Bindora Jiyashitsuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS5297958A publication Critical patent/JPS5297958A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
    • C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B2211/00—Applications
    • B63B2211/02—Oceanography
JP14060576A 1972-07-13 1976-11-22 Production of intermediate of 155substituteddomegaa pentanoprostaglandine Pending JPS5297958A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27122072A 1972-07-13 1972-07-13

Publications (1)

Publication Number Publication Date
JPS5297958A true JPS5297958A (en) 1977-08-17

Family

ID=23034697

Family Applications (4)

Application Number Title Priority Date Filing Date
JP48079214A Expired JPS5241257B2 (en) 1972-07-13 1973-07-13
JP14060676A Pending JPS52122349A (en) 1972-07-13 1976-11-22 Process for preparing tntermediate of 155substituteddomegaa pentanoprostagladines
JP14060776A Pending JPS5293753A (en) 1972-07-13 1976-11-22 Process for preparing intermediate of novel prostaglandine homolog
JP14060576A Pending JPS5297958A (en) 1972-07-13 1976-11-22 Production of intermediate of 155substituteddomegaa pentanoprostaglandine

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP48079214A Expired JPS5241257B2 (en) 1972-07-13 1973-07-13
JP14060676A Pending JPS52122349A (en) 1972-07-13 1976-11-22 Process for preparing tntermediate of 155substituteddomegaa pentanoprostagladines
JP14060776A Pending JPS5293753A (en) 1972-07-13 1976-11-22 Process for preparing intermediate of novel prostaglandine homolog

Country Status (25)

Country Link
JP (4) JPS5241257B2 (en)
AR (2) AR209064A1 (en)
AT (1) AT367033B (en)
BE (1) BE802231A (en)
CA (1) CA1041495A (en)
CH (1) CH593254A5 (en)
CS (1) CS201027B2 (en)
DD (2) DD109210A5 (en)
DE (1) DE2334945A1 (en)
ES (4) ES416865A1 (en)
FI (1) FI57583C (en)
FR (1) FR2192834B1 (en)
GB (1) GB1446341A (en)
HU (4) HU171946B (en)
IE (1) IE37909B1 (en)
IL (2) IL42691A (en)
IN (1) IN138789B (en)
LU (1) LU68015A1 (en)
NL (1) NL7309792A (en)
NO (2) NO143741C (en)
PH (1) PH11461A (en)
SE (3) SE7705947L (en)
SU (4) SU644384A3 (en)
YU (1) YU187773A (en)
ZA (1) ZA734769B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008507506A (en) * 2004-07-23 2008-03-13 ハンミ ファーム． シーオー．， エルティーディー． Method for producing D-erythro-2,2-difluoro-2-deoxy-1-oxoribose derivative

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
DE2463432C2 (en) * 1974-04-03 1987-06-19 Hoechst Ag, 6230 Frankfurt, De
DE2416193C2 (en) 1974-04-03 1985-08-14 Hoechst Ag, 6230 Frankfurt Prostaglandin analogs, processes for their preparation and their use as cytoprotective agents
ZA747723B (en) * 1974-12-11 1976-11-24 Pfizer 11-desoxy-15-substituted-omega-pentanor prostaglandins
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
GB8329559D0 (en) * 1983-11-04 1983-12-07 Erba Farmitalia Furyl derivatives of 16-substituted prostaglandins preparations
SE9002596D0 (en) * 1990-08-08 1990-08-08 Pharmacia Ab A METHOD OF SYNTHESIS OF PROSTAGLANDIN DERIVATIVES
US5972991A (en) * 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US6602900B2 (en) 1992-09-21 2003-08-05 Allergan, Inc. Cyclopentane heptan(ENE)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
AU2014361794B2 (en) * 2013-12-13 2019-04-04 Allergan, Inc. Solid forms of an alpha, omega di-substituted dihydroxy cyclopentyl compound and methods for the preparation and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4975558A (en) * 1972-05-03 1974-07-20

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof
IL50311A (en) * 1972-06-02 1977-08-31 Pfizer Dimethyl alkoxy-2-oxoalkyl phosphonates and their preparattion

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4975558A (en) * 1972-05-03 1974-07-20

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008507506A (en) * 2004-07-23 2008-03-13 ハンミ ファーム． シーオー．， エルティーディー． Method for producing D-erythro-2,2-difluoro-2-deoxy-1-oxoribose derivative

Also Published As

Publication number Publication date
HU172058B (en) 1978-05-28
ES437039A1 (en) 1977-01-01
NO743492L (en) 1974-01-15
GB1446341A (en) 1976-08-18
NL7309792A (en) 1974-01-15
CA1041495A (en) 1978-10-31
ES416865A1 (en) 1976-03-01
ES437037A1 (en) 1977-01-01
SU644384A3 (en) 1979-01-25
AU5778473A (en) 1975-01-09
DD116459A5 (en) 1975-11-20
NO143741C (en) 1981-04-08
ATA620773A (en) 1981-10-15
AR209064A1 (en) 1977-03-31
DD109210A5 (en) 1974-10-20
FR2192834B1 (en) 1979-04-06
FI57583B (en) 1980-05-30
SE7705945L (en) 1977-05-20
HU171156B (en) 1977-11-28
SU645563A3 (en) 1979-01-30
AR214383A1 (en) 1979-06-15
CS201027B2 (en) 1980-10-31
CH593254A5 (en) 1977-11-30
SU645564A3 (en) 1979-01-30
YU187773A (en) 1982-02-25
SU584791A3 (en) 1977-12-15
IN138789B (en) 1976-04-03
FI57583C (en) 1980-09-10
IL50308A0 (en) 1976-10-31
JPS52122349A (en) 1977-10-14
IE37909L (en) 1974-01-13
HU171158B (en) 1977-11-28
BE802231A (en) 1974-01-14
FR2192834A1 (en) 1974-02-15
JPS4992053A (en) 1974-09-03
HU171946B (en) 1978-04-28
AT367033B (en) 1982-05-25
SE7705947L (en) 1977-05-20
LU68015A1 (en) 1974-01-21
SE7705946L (en) 1977-05-20
ZA734769B (en) 1974-06-26
NO144830B (en) 1981-08-10
IL42691A (en) 1979-07-25
NO143741B (en) 1980-12-29
JPS5293753A (en) 1977-08-06
PH11461A (en) 1978-02-01
IE37909B1 (en) 1977-11-09
DE2334945A1 (en) 1974-03-07
NO144830C (en) 1981-11-18
JPS5241257B2 (en) 1977-10-17
ES437038A1 (en) 1977-01-01
IL42691A0 (en) 1973-10-25

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