FR2192834B1 - - Google Patents

Info

Publication number
FR2192834B1
FR2192834B1 FR7325835A FR7325835A FR2192834B1 FR 2192834 B1 FR2192834 B1 FR 2192834B1 FR 7325835 A FR7325835 A FR 7325835A FR 7325835 A FR7325835 A FR 7325835A FR 2192834 B1 FR2192834 B1 FR 2192834B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7325835A
Other versions
FR2192834A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2192834A1 publication Critical patent/FR2192834A1/fr
Priority to FR7730389A priority Critical patent/FR2361381A1/fr
Priority to FR7730390A priority patent/FR2361410A1/fr
Application granted granted Critical
Publication of FR2192834B1 publication Critical patent/FR2192834B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056Esters of arylalkanephosphonic acids
    • C07F9/4059Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B63SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63BSHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B2211/00Applications
    • B63B2211/02Oceanography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
FR7325835A 1972-07-13 1973-07-13 Expired FR2192834B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7730389A FR2361381A1 (fr) 1972-07-13 1977-10-10 Ethers tetrahydropyranyliques, utiles comme intermediaires de synthese de prostaglandines
FR7730390A FR2361410A1 (fr) 1972-07-13 1977-10-10 Alkylphosphonates de dialkyle, utiles comme intermediaires de synthese de prostaglandines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27122072A 1972-07-13 1972-07-13

Publications (2)

Publication Number Publication Date
FR2192834A1 FR2192834A1 (fr) 1974-02-15
FR2192834B1 true FR2192834B1 (fr) 1979-04-06

Family

ID=23034697

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7325835A Expired FR2192834B1 (fr) 1972-07-13 1973-07-13

Country Status (25)

Country Link
JP (4) JPS5241257B2 (fr)
AR (2) AR209064A1 (fr)
AT (1) AT367033B (fr)
BE (1) BE802231A (fr)
CA (1) CA1041495A (fr)
CH (1) CH593254A5 (fr)
CS (1) CS201027B2 (fr)
DD (2) DD109210A5 (fr)
DE (1) DE2334945A1 (fr)
ES (4) ES416865A1 (fr)
FI (1) FI57583C (fr)
FR (1) FR2192834B1 (fr)
GB (1) GB1446341A (fr)
HU (4) HU171158B (fr)
IE (1) IE37909B1 (fr)
IL (2) IL42691A (fr)
IN (1) IN138789B (fr)
LU (1) LU68015A1 (fr)
NL (1) NL7309792A (fr)
NO (2) NO143741C (fr)
PH (1) PH11461A (fr)
SE (3) SE7705947L (fr)
SU (4) SU644384A3 (fr)
YU (1) YU187773A (fr)
ZA (1) ZA734769B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
DE2463432C2 (fr) * 1974-04-03 1987-06-19 Hoechst Ag, 6230 Frankfurt, De
DE2416193C2 (de) 1974-04-03 1985-08-14 Hoechst Ag, 6230 Frankfurt Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel
ZA747723B (en) * 1974-12-11 1976-11-24 Pfizer 11-desoxy-15-substituted-omega-pentanor prostaglandins
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
GB8329559D0 (en) * 1983-11-04 1983-12-07 Erba Farmitalia Furyl derivatives of 16-substituted prostaglandins preparations
SE9002596D0 (sv) * 1990-08-08 1990-08-08 Pharmacia Ab A method for synthesis of prostaglandin derivatives
US6602900B2 (en) 1992-09-21 2003-08-05 Allergan, Inc. Cyclopentane heptan(ENE)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US5972991A (en) * 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
KR100578616B1 (ko) * 2004-07-23 2006-05-10 한미약품 주식회사 D-에리트로-2,2-다이플루오로-2-데옥시-1-옥소라이보스화합물의 제조방법
BR112016013594A8 (pt) * 2013-12-13 2020-05-19 Allergan Inc formas cristalinas de um composto dihidroxi ciclopentil alfa, ômega-dissubstituído, composição farmacêutica, métodos para o preparo e uso das mesmas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
IL42373A (en) * 1972-06-02 1977-08-31 Pfizer Oxaprostagliandins and their preparation

Also Published As

Publication number Publication date
JPS4992053A (fr) 1974-09-03
AR214383A1 (es) 1979-06-15
SE7705946L (sv) 1977-05-20
ZA734769B (en) 1974-06-26
ES437038A1 (es) 1977-01-01
SU645564A3 (ru) 1979-01-30
SE7705945L (sv) 1977-05-20
DD109210A5 (fr) 1974-10-20
IL42691A0 (en) 1973-10-25
AT367033B (de) 1982-05-25
ES437039A1 (es) 1977-01-01
DD116459A5 (fr) 1975-11-20
IL42691A (en) 1979-07-25
FR2192834A1 (fr) 1974-02-15
CS201027B2 (en) 1980-10-31
CA1041495A (fr) 1978-10-31
NL7309792A (fr) 1974-01-15
JPS5297958A (en) 1977-08-17
HU172058B (hu) 1978-05-28
ES416865A1 (es) 1976-03-01
SE7705947L (sv) 1977-05-20
IN138789B (fr) 1976-04-03
PH11461A (en) 1978-02-01
AR209064A1 (es) 1977-03-31
BE802231A (fr) 1974-01-14
SU584791A3 (ru) 1977-12-15
JPS52122349A (en) 1977-10-14
HU171156B (hu) 1977-11-28
ATA620773A (de) 1981-10-15
NO143741C (no) 1981-04-08
JPS5293753A (en) 1977-08-06
JPS5241257B2 (fr) 1977-10-17
HU171158B (hu) 1977-11-28
IE37909L (en) 1974-01-13
HU171946B (hu) 1978-04-28
IE37909B1 (en) 1977-11-09
YU187773A (en) 1982-02-25
NO144830B (no) 1981-08-10
SU644384A3 (ru) 1979-01-25
AU5778473A (en) 1975-01-09
CH593254A5 (fr) 1977-11-30
LU68015A1 (fr) 1974-01-21
GB1446341A (en) 1976-08-18
SU645563A3 (ru) 1979-01-30
NO144830C (no) 1981-11-18
IL50308A0 (en) 1976-10-31
FI57583B (fi) 1980-05-30
FI57583C (fi) 1980-09-10
NO143741B (no) 1980-12-29
ES437037A1 (es) 1977-01-01
NO743492L (no) 1974-01-15
DE2334945A1 (de) 1974-03-07

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Legal Events

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ST Notification of lapse