SE7612262L - Ketofosfonat-mellanprodukter och forfarande for framstellning derav - Google Patents

Ketofosfonat-mellanprodukter och forfarande for framstellning derav

Info

Publication number
SE7612262L
SE7612262L SE7612262A SE7612262A SE7612262L SE 7612262 L SE7612262 L SE 7612262L SE 7612262 A SE7612262 A SE 7612262A SE 7612262 A SE7612262 A SE 7612262A SE 7612262 L SE7612262 L SE 7612262L
Authority
SE
Sweden
Prior art keywords
alpha
trans
dimethylisopropylsilyloxy
pentanor
indanyl
Prior art date
Application number
SE7612262A
Other languages
English (en)
Inventor
H-J E Hess
T K Schaaf
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE7612262L publication Critical patent/SE7612262L/sv

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/30Compounds having groups
    • C07C43/315Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30Unsaturated compounds
    • C07C62/34Unsaturated compounds containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018Esters of cycloaliphatic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SE7612262A 1972-11-08 1976-11-03 Ketofosfonat-mellanprodukter och forfarande for framstellning derav SE7612262L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30475072A 1972-11-08 1972-11-08

Publications (1)

Publication Number Publication Date
SE7612262L true SE7612262L (sv) 1976-11-03

Family

ID=23177829

Family Applications (4)

Application Number Title Priority Date Filing Date
SE7315074A SE412229B (sv) 1972-11-08 1973-11-06 Analogiforfarande for framstellning av vissa omega-substituerade prostaglandinanaloger
SE7612262A SE7612262L (sv) 1972-11-08 1976-11-03 Ketofosfonat-mellanprodukter och forfarande for framstellning derav
SE7612261A SE7612261L (sv) 1972-11-08 1976-11-03 Prostaglandinmellanprodukter
SE7701523A SE417957B (sv) 1972-11-08 1977-02-10 Omega-substituerade prostaglandinanaloger till anvendning som antifertilitetsmedel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7315074A SE412229B (sv) 1972-11-08 1973-11-06 Analogiforfarande for framstellning av vissa omega-substituerade prostaglandinanaloger

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE7612261A SE7612261L (sv) 1972-11-08 1976-11-03 Prostaglandinmellanprodukter
SE7701523A SE417957B (sv) 1972-11-08 1977-02-10 Omega-substituerade prostaglandinanaloger till anvendning som antifertilitetsmedel

Country Status (20)

Country Link
JP (1) JPS5714347B2 (sv)
AT (1) AT345999B (sv)
BE (1) BE807046A (sv)
CA (1) CA1033727A (sv)
CH (1) CH593930A5 (sv)
DE (1) DE2355731C3 (sv)
DK (1) DK143499C (sv)
ES (3) ES420386A1 (sv)
FI (1) FI58912C (sv)
FR (3) FR2205338B1 (sv)
GB (1) GB1456838A (sv)
IE (1) IE40043B1 (sv)
IL (2) IL50310A (sv)
IN (1) IN139265B (sv)
NL (1) NL7315307A (sv)
NO (2) NO143663C (sv)
PH (2) PH13261A (sv)
SE (4) SE412229B (sv)
SU (2) SU667131A3 (sv)
ZA (1) ZA738595B (sv)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
JPS5823393B2 (ja) * 1974-03-14 1983-05-14 オノヤクヒンコウギヨウ カブシキガイシヤ プロスタグランジンルイジカゴウブツ ノ セイゾウホウホウ
US4028396A (en) * 1975-07-02 1977-06-07 American Cyanamid Company 16,16-Spirocycloalkyl prostaglandin derivatives
NZ183136A (en) * 1976-02-11 1978-11-13 Miles Lab Monospiroalkyl derivatives of prostaclandis and pharmaceutical compositions
US4074063A (en) * 1976-02-11 1978-02-14 Miles Laboratories, Inc. Bicycloalkyl derivatives of prostaglandins
US4404372A (en) * 1977-06-13 1983-09-13 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandin derivatives
DE2753995A1 (de) * 1977-12-03 1979-06-07 Bayer Ag Neue bicycloalkenyl-prostaglandine und verfahren zu ihrer herstellung
US6048895A (en) * 1997-09-09 2000-04-11 The Procter & Gamble Company Aromatic C16-C20 substituted tetrahydro prostaglandins useful as FP agonists
US5977173A (en) * 1997-09-09 1999-11-02 Wos; John August Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists
IL134792A0 (en) * 1997-09-09 2001-04-30 Procter & Gamble Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
EP1159266B1 (en) * 1999-03-05 2004-11-03 Duke University C-16 unsaturated fp-selective prostaglandins analogs
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
ATE432910T1 (de) * 2007-11-28 2009-06-15 Bauer Maschinen Gmbh Winde
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20230097470A1 (en) * 2021-08-23 2023-03-30 Chirogate International Inc. Processes and intermediates for the preparations of carboprost and carboprost tromethamine, and carboprost tromethamine prepared therefrom

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4864073A (sv) * 1971-04-30 1973-09-05

Also Published As

Publication number Publication date
IE40043L (en) 1974-05-08
CH593930A5 (sv) 1977-12-30
FI58912C (fi) 1981-05-11
IN139265B (sv) 1976-05-29
PH13261A (en) 1980-02-25
FR2205338A1 (sv) 1974-05-31
ES444398A1 (es) 1977-12-01
JPS49133357A (sv) 1974-12-21
PH13320A (en) 1980-03-13
NL7315307A (sv) 1974-05-10
IE40043B1 (en) 1979-02-28
DK143499B (da) 1981-08-31
AT345999B (de) 1978-10-10
AU6230273A (en) 1975-05-08
ZA738595B (en) 1974-09-25
DE2355731C3 (de) 1981-01-15
IL43571A0 (en) 1974-03-14
FR2286147B1 (sv) 1978-09-22
FR2205338B1 (sv) 1978-07-13
DK143499C (da) 1982-01-11
SE7701523L (sv) 1977-02-10
SE412229B (sv) 1980-02-25
ATA941073A (de) 1978-02-15
NO143663C (no) 1981-03-25
SE7612261L (sv) 1976-11-03
DE2355731A1 (de) 1974-05-22
ES420386A1 (es) 1976-07-01
FI58912B (fi) 1981-01-30
NO143663B (no) 1980-12-15
JPS5714347B2 (sv) 1982-03-24
GB1456838A (en) 1976-11-24
SE417957B (sv) 1981-04-27
NO743616L (no) 1974-05-09
IL50310A (en) 1977-08-31
FR2291200A1 (fr) 1976-06-11
SU667131A3 (ru) 1979-06-05
ES456279A1 (es) 1978-11-01
SU704456A3 (ru) 1979-12-15
IL43571A (en) 1977-08-31
DE2355731B2 (de) 1980-04-30
BE807046A (fr) 1974-05-08
NO144385C (no) 1981-08-19
NO144385B (no) 1981-05-11
FR2291200B1 (sv) 1979-01-05
CA1033727A (en) 1978-06-27
FR2286147A1 (fr) 1976-04-23

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