BE807046A - Omega-pentanorprostaglandines - Google Patents

Omega-pentanorprostaglandines

Info

Publication number
BE807046A
BE807046A BE1005488A BE1005488A BE807046A BE 807046 A BE807046 A BE 807046A BE 1005488 A BE1005488 A BE 1005488A BE 1005488 A BE1005488 A BE 1005488A BE 807046 A BE807046 A BE 807046A
Authority
BE
Belgium
Prior art keywords
pentanorprostaglandins
omega
Prior art date
Application number
BE1005488A
Other languages
English (en)
French (fr)
Inventor
H J E Hess
Th K Schaaf
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE807046A publication Critical patent/BE807046A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018—Esters of cycloaliphatic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
BE1005488A 1972-11-08 1973-11-08 Omega-pentanorprostaglandines BE807046A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30475072A 1972-11-08 1972-11-08

Publications (1)

Publication Number Publication Date
BE807046A true BE807046A (fr) 1974-05-08

Family

ID=23177829

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1005488A BE807046A (fr) 1972-11-08 1973-11-08 Omega-pentanorprostaglandines

Country Status (20)

Country Link
JP (1) JPS5714347B2 (xx)
AT (1) AT345999B (xx)
BE (1) BE807046A (xx)
CA (1) CA1033727A (xx)
CH (1) CH593930A5 (xx)
DE (1) DE2355731C3 (xx)
DK (1) DK143499C (xx)
ES (3) ES420386A1 (xx)
FI (1) FI58912C (xx)
FR (3) FR2205338B1 (xx)
GB (1) GB1456838A (xx)
IE (1) IE40043B1 (xx)
IL (2) IL43571A (xx)
IN (1) IN139265B (xx)
NL (1) NL7315307A (xx)
NO (2) NO143663C (xx)
PH (2) PH13261A (xx)
SE (4) SE412229B (xx)
SU (2) SU667131A3 (xx)
ZA (1) ZA738595B (xx)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
US4004021A (en) * 1973-01-31 1977-01-18 Imperial Chemical Industries Limited Cyclopentane derivatives
US4028396A (en) * 1975-07-02 1977-06-07 American Cyanamid Company 16,16-Spirocycloalkyl prostaglandin derivatives
US4045468A (en) * 1974-03-14 1977-08-30 Ono Pharmaceutical Company 16-Cyclobutyl-prostaglandins

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4074063A (en) * 1976-02-11 1978-02-14 Miles Laboratories, Inc. Bicycloalkyl derivatives of prostaglandins
NZ183136A (en) * 1976-02-11 1978-11-13 Miles Lab Monospiroalkyl derivatives of prostaclandis and pharmaceutical compositions
US4404372A (en) * 1977-06-13 1983-09-13 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandin derivatives
DE2753995A1 (de) * 1977-12-03 1979-06-07 Bayer Ag Neue bicycloalkenyl-prostaglandine und verfahren zu ihrer herstellung
WO1999012898A1 (en) * 1997-09-09 1999-03-18 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
CN1269785A (zh) * 1997-09-09 2000-10-11 普罗克特和甘保尔公司 用作fp激活剂的芳香族c16－c20－取代四氢前列腺素
DE69824966T2 (de) * 1997-09-09 2005-04-07 Duke University Aromatische c16-c20-substituierte tetrahydro-prostaglandine verwendbar wie fp agoniste
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ Ｃ１６不飽和ｆｐ−選択的プロスタグランジン類縁体
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
ATE432910T1 (de) * 2007-11-28 2009-06-15 Bauer Maschinen Gmbh Winde
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20230097470A1 (en) * 2021-08-23 2023-03-30 Chirogate International Inc. Processes and intermediates for the preparations of carboprost and carboprost tromethamine, and carboprost tromethamine prepared therefrom

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4864073A (xx) * 1971-04-30 1973-09-05

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004021A (en) * 1973-01-31 1977-01-18 Imperial Chemical Industries Limited Cyclopentane derivatives
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
US4045468A (en) * 1974-03-14 1977-08-30 Ono Pharmaceutical Company 16-Cyclobutyl-prostaglandins
US4028396A (en) * 1975-07-02 1977-06-07 American Cyanamid Company 16,16-Spirocycloalkyl prostaglandin derivatives

Also Published As

Publication number Publication date
FR2291200A1 (fr) 1976-06-11
PH13261A (en) 1980-02-25
CH593930A5 (xx) 1977-12-30
SE7701523L (sv) 1977-02-10
FR2205338B1 (xx) 1978-07-13
IN139265B (xx) 1976-05-29
NL7315307A (xx) 1974-05-10
FR2291200B1 (xx) 1979-01-05
NO144385B (no) 1981-05-11
NO143663C (no) 1981-03-25
DK143499C (da) 1982-01-11
DE2355731A1 (de) 1974-05-22
IL43571A0 (en) 1974-03-14
ES420386A1 (es) 1976-07-01
IL43571A (en) 1977-08-31
GB1456838A (en) 1976-11-24
ES444398A1 (es) 1977-12-01
IL50310A (en) 1977-08-31
JPS5714347B2 (xx) 1982-03-24
DE2355731C3 (de) 1981-01-15
FR2286147A1 (fr) 1976-04-23
DE2355731B2 (de) 1980-04-30
NO143663B (no) 1980-12-15
ATA941073A (de) 1978-02-15
SE7612262L (sv) 1976-11-03
PH13320A (en) 1980-03-13
IE40043L (en) 1974-05-08
AT345999B (de) 1978-10-10
SU704456A3 (ru) 1979-12-15
SE7612261L (sv) 1976-11-03
NO144385C (no) 1981-08-19
FI58912B (fi) 1981-01-30
IE40043B1 (en) 1979-02-28
SE412229B (sv) 1980-02-25
SE417957B (sv) 1981-04-27
FI58912C (fi) 1981-05-11
JPS49133357A (xx) 1974-12-21
ZA738595B (en) 1974-09-25
DK143499B (da) 1981-08-31
AU6230273A (en) 1975-05-08
FR2205338A1 (xx) 1974-05-31
CA1033727A (en) 1978-06-27
NO743616L (no) 1974-05-09
ES456279A1 (es) 1978-11-01
FR2286147B1 (xx) 1978-09-22
SU667131A3 (ru) 1979-06-05

Similar Documents

Publication Publication Date Title
BE795162A (fr) Injektie-inrichting
BE793731A (fr) Electrogenerateurs
BE794087A (nl) Polyepoxyden
BE793764A (fr) Integrerende weeginrichting
AT324072B (de) Wendelbohreb
AT353108B (de) Skibob
BE795790A (fr) Dibenzo-triazolo-azepine
BE790615A (fr) Houderdrager
AT323930B (de) Untermatratze
DK134042C (da) Herbicid
BE793718A (fr) Aminobenzimidazoles
BE793745A (fr) Antistatische polystyreencomposities
BE795272A (fr) Boorinrichting
BE791330A (fr) Houderdrager
BE795808A (fr) Amidazoles polysubstitues
BE796355A (fr) Decalcomanies
AT322779B (de) Bücherbrett
AT335953B (de) Lauterboden
BE793934A (fr) 15-oxasteroides
BE794891A (fr) Bigoudi
BE794421A (fr) Verduurzaamde smeervetdsamenstellingen
BE791976A (fr) Sandalette
BE779066A (fr) Herenjas
BE782546A (fr) Aansluitdoos
BE793926A (fr) Mengselscheiding