AT344159B - Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saeureadditionssalze - Google Patents
Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saeureadditionssalzeInfo
- Publication number
- AT344159B AT344159B AT722875A AT722875A AT344159B AT 344159 B AT344159 B AT 344159B AT 722875 A AT722875 A AT 722875A AT 722875 A AT722875 A AT 722875A AT 344159 B AT344159 B AT 344159B
- Authority
- AT
- Austria
- Prior art keywords
- phenylimino
- imidazolidine
- disubstituted
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2446758A DE2446758C3 (de) | 1974-10-01 | 1974-10-01 | 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA722875A ATA722875A (de) | 1977-11-15 |
| AT344159B true AT344159B (de) | 1978-07-10 |
Family
ID=5927202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT722875A AT344159B (de) | 1974-10-01 | 1975-09-22 | Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saeureadditionssalze |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS6018653B2 (hu) |
| AT (1) | AT344159B (hu) |
| BE (1) | BE834051A (hu) |
| BG (2) | BG25220A3 (hu) |
| CA (1) | CA1056836A (hu) |
| CH (5) | CH620682A5 (hu) |
| CS (1) | CS193524B2 (hu) |
| DD (1) | DD123602A5 (hu) |
| DE (1) | DE2446758C3 (hu) |
| DK (1) | DK441875A (hu) |
| ES (4) | ES441385A1 (hu) |
| FI (1) | FI61883C (hu) |
| FR (1) | FR2286649A1 (hu) |
| GB (1) | GB1515019A (hu) |
| HU (1) | HU178469B (hu) |
| IE (1) | IE42130B1 (hu) |
| IL (1) | IL48214A (hu) |
| LU (1) | LU73472A1 (hu) |
| NL (1) | NL7511490A (hu) |
| NO (1) | NO143459C (hu) |
| NZ (1) | NZ178810A (hu) |
| PH (1) | PH13653A (hu) |
| PL (2) | PL98984B1 (hu) |
| SE (1) | SE418497B (hu) |
| SU (1) | SU575026A3 (hu) |
| YU (1) | YU230281A (hu) |
| ZA (1) | ZA756185B (hu) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2630060C2 (de) * | 1976-07-03 | 1984-04-19 | C.H. Boehringer Sohn, 6507 Ingelheim | 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung |
| DE2806775A1 (de) * | 1978-02-17 | 1979-08-30 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
| DE2806811A1 (de) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben |
| CA1138451A (en) * | 1979-04-03 | 1982-12-28 | Ikuo Ueda | 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same |
| HU192986B (en) * | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
| CN101370500A (zh) * | 2006-01-27 | 2009-02-18 | 弗·哈夫曼-拉罗切有限公司 | 2-咪唑化合物用于治疗cns障碍的用途 |
| RU2473545C2 (ru) | 2007-02-02 | 2013-01-27 | Ф.Хоффманн-Ля Рош Аг | Новые 2-аминооксазолины в качестве лигандов taar1 для заболеваний цнс |
| KR101222412B1 (ko) | 2007-02-15 | 2013-01-15 | 에프. 호프만-라 로슈 아게 | Ｔａａｒ1 리간드로서의 2-아미노옥사졸린 |
| US8242153B2 (en) | 2008-07-24 | 2012-08-14 | Hoffmann-La Roche Inc. | 4,5-dihydro-oxazol-2YL derivatives |
| US8354441B2 (en) | 2009-11-11 | 2013-01-15 | Hoffmann-La Roche Inc. | Oxazoline derivatives |
| US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| JP6814814B2 (ja) | 2016-03-17 | 2021-01-20 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｔａａｒのアゴニストとしての活性を有する５−エチル−４−メチル−ピラゾール−３−カルボキサミド誘導体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3236857A (en) * | 1961-10-09 | 1966-02-22 | Boehringer Sohn Ingelheim | 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products |
| DE1670807A1 (de) * | 1967-02-17 | 1971-03-11 | Bayer Ag | Verfahren zur Herstellung von cyclischen Guanidinen |
| DE1670918A1 (de) * | 1967-09-07 | 1971-04-08 | Bayer Ag | Verfahren zur Herstellung von 2-Aryl-amino-substituierten stickstoffhaltigen Heterocyclen |
| BE787683A (fr) * | 1971-08-20 | 1973-02-19 | Boehringer Sohn Ingelheim | 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer |
-
1974
- 1974-10-01 DE DE2446758A patent/DE2446758C3/de not_active Expired
-
1975
- 1975-09-22 AT AT722875A patent/AT344159B/de not_active IP Right Cessation
- 1975-09-23 SU SU7502174605A patent/SU575026A3/ru active
- 1975-09-26 PH PH17613A patent/PH13653A/en unknown
- 1975-09-29 LU LU73472A patent/LU73472A1/xx unknown
- 1975-09-29 DD DD188613A patent/DD123602A5/xx unknown
- 1975-09-29 CS CS756573A patent/CS193524B2/cs unknown
- 1975-09-29 BG BG031110A patent/BG25220A3/xx unknown
- 1975-09-29 BG BG032014A patent/BG25221A3/xx unknown
- 1975-09-30 IL IL48214A patent/IL48214A/xx unknown
- 1975-09-30 NL NL7511490A patent/NL7511490A/xx not_active Application Discontinuation
- 1975-09-30 GB GB40012/75A patent/GB1515019A/en not_active Expired
- 1975-09-30 PL PL1975197816A patent/PL98984B1/pl unknown
- 1975-09-30 FI FI752728A patent/FI61883C/fi not_active IP Right Cessation
- 1975-09-30 NO NO753314A patent/NO143459C/no unknown
- 1975-09-30 JP JP50118196A patent/JPS6018653B2/ja not_active Expired
- 1975-09-30 ZA ZA756185A patent/ZA756185B/xx unknown
- 1975-09-30 DK DK441875A patent/DK441875A/da not_active Application Discontinuation
- 1975-09-30 PL PL1975183670A patent/PL97003B1/pl unknown
- 1975-09-30 NZ NZ178810A patent/NZ178810A/xx unknown
- 1975-09-30 CH CH1267875A patent/CH620682A5/de not_active IP Right Cessation
- 1975-09-30 CA CA236,670A patent/CA1056836A/en not_active Expired
- 1975-09-30 BE BE160578A patent/BE834051A/xx not_active IP Right Cessation
- 1975-09-30 ES ES441385A patent/ES441385A1/es not_active Expired
- 1975-09-30 HU HU75BO1573A patent/HU178469B/hu unknown
- 1975-10-01 FR FR7530117A patent/FR2286649A1/fr active Granted
- 1975-10-01 SE SE7511028A patent/SE418497B/xx not_active IP Right Cessation
- 1975-10-01 IE IE2150/75A patent/IE42130B1/en unknown
-
1976
- 1976-02-04 ES ES444898A patent/ES444898A1/es not_active Expired
- 1976-02-04 ES ES444901A patent/ES444901A1/es not_active Expired
- 1976-02-04 ES ES444900A patent/ES444900A1/es not_active Expired
-
1980
- 1980-07-01 CH CH506480A patent/CH626352A5/de not_active IP Right Cessation
- 1980-07-01 CH CH506280A patent/CH627452A5/de not_active IP Right Cessation
- 1980-07-01 CH CH506580A patent/CH627454A5/de not_active IP Right Cessation
- 1980-07-01 CH CH506380A patent/CH627453A5/de not_active IP Right Cessation
-
1981
- 1981-09-24 YU YU02302/81A patent/YU230281A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |