AT272522B - Verfahren zur Herstellung von stabilen, für die parenterale und perorale Verabreichung geeigneten wässerigen Lösungen von Oxytetracyclin - Google Patents

Verfahren zur Herstellung von stabilen, für die parenterale und perorale Verabreichung geeigneten wässerigen Lösungen von Oxytetracyclin

Info

Publication number
AT272522B
AT272522B AT502267A AT502267A AT272522B AT 272522 B AT272522 B AT 272522B AT 502267 A AT502267 A AT 502267A AT 502267 A AT502267 A AT 502267A AT 272522 B AT272522 B AT 272522B
Authority
AT
Austria
Prior art keywords
oxytetracycline
parenteral
preparation
aqueous solutions
stable aqueous
Prior art date
Application number
AT502267A
Other languages
German (de)
English (en)
Original Assignee
Koninklijke Gist Spiritus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Gist Spiritus filed Critical Koninklijke Gist Spiritus
Application granted granted Critical
Publication of AT272522B publication Critical patent/AT272522B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT502267A 1966-05-31 1967-05-30 Verfahren zur Herstellung von stabilen, für die parenterale und perorale Verabreichung geeigneten wässerigen Lösungen von Oxytetracyclin AT272522B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6607516A NL6607516A (OSRAM) 1966-05-31 1966-05-31

Publications (1)

Publication Number Publication Date
AT272522B true AT272522B (de) 1969-07-10

Family

ID=19796753

Family Applications (1)

Application Number Title Priority Date Filing Date
AT502267A AT272522B (de) 1966-05-31 1967-05-30 Verfahren zur Herstellung von stabilen, für die parenterale und perorale Verabreichung geeigneten wässerigen Lösungen von Oxytetracyclin

Country Status (22)

Country Link
US (1) US3557280A (OSRAM)
JP (1) JPS5010373B1 (OSRAM)
AT (1) AT272522B (OSRAM)
BE (1) BE699091A (OSRAM)
CH (1) CH490087A (OSRAM)
CS (1) CS151454B2 (OSRAM)
DE (1) DE1617576C3 (OSRAM)
DK (1) DK117587B (OSRAM)
ES (1) ES340956A1 (OSRAM)
FI (1) FI43622B (OSRAM)
FR (1) FR5953M (OSRAM)
GB (1) GB1131007A (OSRAM)
GR (1) GR33861B (OSRAM)
IL (1) IL28009A (OSRAM)
IT (1) IT1140250B (OSRAM)
LU (1) LU53788A1 (OSRAM)
MY (1) MY7100015A (OSRAM)
NL (1) NL6607516A (OSRAM)
NO (1) NO126298B (OSRAM)
SE (1) SE354417B (OSRAM)
SU (1) SU510986A3 (OSRAM)
YU (1) YU31326B (OSRAM)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5418330B2 (OSRAM) * 1973-03-16 1979-07-06
US3966905A (en) * 1973-05-29 1976-06-29 Barnes-Hind Pharmaceuticals, Inc. Stabilized catechol amine solutions
US3929989A (en) * 1974-06-14 1975-12-30 Wendt Lab Inc Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
US4259331A (en) * 1979-04-16 1981-03-31 Pfizer Inc. Oxytetracycline compositions
US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0626171A1 (de) * 1993-05-26 1994-11-30 Winfried Dörnhöfer Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
CZ301835B6 (cs) 1999-09-14 2010-07-07 Trustees Of Tufts College Zpusob prípravy 7-, 9- nebo 13- substituované tetracyklinové slouceniny, reaktivní tetracyklinový chemický komplex a tetracyklinová sloucenina substituovaná v poloze 7 nebo 9
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6833365B2 (en) 2000-01-24 2004-12-21 Trustees Of Tufts College Tetracycline compounds for treatment of Cryptosporidium parvum related disorders
DE60129116T2 (de) 2000-03-31 2008-03-13 Trustees Of Tufts College, Medford 7- und 9-carbamat, harnstoff, thioharnstoff, thiocarbamat und heteroaryl-amino substituierte tetracyclinverbindungen
CA2409063A1 (en) * 2000-05-15 2001-11-22 Mark L. Nelson 7-substituted fused ring tetracycline compounds
US20040224927A1 (en) * 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
AU2001268475A1 (en) * 2000-06-16 2002-01-02 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
JP4963771B2 (ja) 2000-07-07 2012-06-27 トラスティーズ・オブ・タフツ・カレッジ 7、8および9−置換テトラサイクリン化合物
CN1452611A (zh) 2000-07-07 2003-10-29 塔夫茨大学信托人 13-取代甲烯土霉素化合物
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
KR101027625B1 (ko) 2000-07-07 2011-04-06 파라테크 파마슈티컬스, 인크. 7-치환 테트라사이클린 화합물
AU2001286388B2 (en) 2000-07-07 2005-07-14 Paratek Pharmaceuticals, Inc. 9-substituted minocycline compounds
HUP0402047A3 (en) 2001-03-13 2012-10-29 Paratek Pharmaceuticals 7,9-substituted tetracycline compounds, their use and pharmaceutical compositions containing them
AU2002250331A1 (en) * 2001-03-13 2002-09-24 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
US7045507B2 (en) 2001-03-14 2006-05-16 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
EP1379255A2 (en) 2001-03-14 2004-01-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
AU2002254714C1 (en) 2001-04-24 2010-01-07 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2322501B1 (en) 2002-01-08 2015-08-05 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
KR101014918B1 (ko) 2002-03-08 2011-02-15 파라테크 파마슈티컬스, 인크. 아미노-메틸 치환된 테트라시클린 화합물
EP2481723A3 (en) 2002-03-21 2013-02-13 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP2345637A3 (en) 2002-07-12 2012-02-15 Paratek Pharmaceuticals, Inc. 3, 10, and 12a substituted tetracycline compounds
EP2277504A1 (en) 2002-10-24 2011-01-26 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
AU2003261633A1 (en) * 2003-02-12 2004-09-06 R And P Korea Co., Ltd. Solvent system of hardly soluble drug with improved elution rate
JP4738333B2 (ja) 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド 9−アミノメチルテトラサイクリン化合物のプロドラッグ
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
CA2531728A1 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
WO2005070878A1 (en) * 2004-01-15 2005-08-04 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2269978A3 (en) 2004-10-25 2011-09-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP1805134B1 (en) 2004-10-25 2012-06-20 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
AU2006210406C1 (en) 2005-02-04 2013-03-07 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
DE102005012595A1 (de) * 2005-03-18 2006-09-21 Lanxess Deutschland Gmbh Herstellung von Tri(chlorpropyl)phosphat
WO2007014154A2 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
WO2007035448A2 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
AU2007208214B2 (en) 2006-01-24 2013-02-14 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
ES2622356T3 (es) * 2006-04-24 2017-07-06 Teva Pharmaceutical Industries, Ltd. Formas cristalinas de tigeciclina y procesos para su preparación
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
JP2009537139A (ja) * 2006-05-15 2009-10-29 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物を用いて、遺伝子または遺伝子産物の発現を制御する方法
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
TR201818983T4 (tr) 2006-12-21 2019-01-21 Paratek Pharm Innc İnflamatuvar Cilt Bozukluklarının Tedavisine Yönelik Olarak Sübstitüe Edilmiş Tetrasiklin Bileşikleri
IL302749A (en) 2006-12-21 2023-07-01 Paratek Pharm Innc A tetracycline compound, a pharmaceutical preparation containing the tetracycline compound, and the tetracycline compound or the pharmaceutical preparation for the treatment of the tetracycline-responsive condition
EP2144614A1 (en) * 2007-04-12 2010-01-20 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
EP2213655A1 (en) 2007-04-27 2010-08-04 Paratek Pharmaceuticals, Inc. Methods For Purifying Aminoalkyl Tetracycline Compounds
CN101811980A (zh) 2007-07-06 2010-08-25 帕拉特克药品公司 合成取代的四环素化合物的方法
MX2010009693A (es) 2008-03-05 2010-12-20 Paratek Pharm Innc Compuestos de monociclina y metodos de uso de la misma.
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
WO2009128913A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TW202216656A (zh) 2008-05-19 2022-05-01 美商Prtk Spv2公司 四環素化合物之甲苯磺酸鹽及同素異形體
US9629806B2 (en) * 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
EP2341771A4 (en) * 2008-09-19 2012-08-15 Paratek Pharm Innc TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS AND RELATED THERAPEUTIC METHODS
EP2990051B1 (en) 2009-04-10 2016-10-26 Tufts Medical Center, Inc. Par-1 activation by metalloproteinase-1 (mmp-1)
HRP20191295T8 (hr) 2011-05-12 2020-02-07 Paratek Pharmaceuticals, Inc. Kristalne soli amida (4s,4as,5ar,12as)-4-dimetilamino-3,10,12,12a-tetrahidroksi-7-[(metoksi(metil)amino)-metil]-1,11-diokso-1,4,4a,5,5a,6,11,12a-oktahidro-naftacen-2-karboksilne kiseline i postupci uporabe istih
BR112019008897A2 (pt) 2016-11-01 2019-08-13 Paratek Pharm Innc método para tratar pneumonia bacteriana adquirida na comunidade.
AU2018303807B2 (en) 2017-07-21 2023-08-24 Almirall, Llc Treatment of non-inflammatory lesions

Also Published As

Publication number Publication date
FR5953M (OSRAM) 1968-04-16
IT1140250B (it) 1986-09-24
IL28009A (en) 1970-08-19
CS151454B2 (OSRAM) 1973-10-19
FI43622B (OSRAM) 1971-02-01
JPS5010373B1 (OSRAM) 1975-04-21
DE1617576B2 (de) 1980-04-10
YU31326B (en) 1973-04-30
LU53788A1 (OSRAM) 1967-07-31
SE354417B (OSRAM) 1973-03-12
NL6607516A (OSRAM) 1967-12-01
CH490087A (de) 1970-05-15
ES340956A1 (es) 1968-06-16
DK117587B (da) 1970-05-11
GB1131007A (en) 1968-10-16
GR33861B (el) 1968-02-09
BE699091A (OSRAM) 1967-11-27
DE1617576C3 (de) 1980-12-11
SU510986A3 (ru) 1976-04-15
DE1617576A1 (de) 1972-04-27
US3557280A (en) 1971-01-19
NO126298B (OSRAM) 1973-01-22
MY7100015A (en) 1971-12-31

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