CH490319A - Verfahren zur Herstellung von neuen Amino-dihalogen-phenyläthylaminen - Google Patents

Verfahren zur Herstellung von neuen Amino-dihalogen-phenyläthylaminen

Info

Publication number
CH490319A
CH490319A CH1309567A CH1309567A CH490319A CH 490319 A CH490319 A CH 490319A CH 1309567 A CH1309567 A CH 1309567A CH 1309567 A CH1309567 A CH 1309567A CH 490319 A CH490319 A CH 490319A
Authority
CH
Switzerland
Prior art keywords
phenylethylamines
dihalogen
preparation
new amino
amino
Prior art date
Application number
CH1309567A
Other languages
English (en)
Inventor
Johannes Dr Keck
Gerd Dr Krueger
Hans Dr Machleidt
Klaus Dr Noll
Guenther Dr Engelhardt
Albrecht Dr Eckenfels
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Priority to CH324570A priority Critical patent/CH507199A/de
Priority to CH324770A priority patent/CH489462A/de
Priority to CH324670A priority patent/CH490320A/de
Publication of CH490319A publication Critical patent/CH490319A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1309567A 1966-09-22 1967-09-19 Verfahren zur Herstellung von neuen Amino-dihalogen-phenyläthylaminen CH490319A (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CH324570A CH507199A (de) 1966-09-22 1967-09-19 Verfahren zur Herstellung von neuen Amino-dihalogenphenyläthylaminen
CH324770A CH489462A (de) 1966-09-22 1967-09-19 Verfahren zur Herstellung von neuen Amino-dihalogenphenyläthylaminen
CH324670A CH490320A (de) 1966-09-22 1967-09-19 Verfahren zur Herstellung von neuen Amino-dihalogenphenyl-äthylaminen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DET0032111 1966-09-22
DET0033217 1967-02-15
DET0034019 1967-06-02

Publications (1)

Publication Number Publication Date
CH490319A true CH490319A (de) 1970-05-15

Family

ID=27213171

Family Applications (2)

Application Number Title Priority Date Filing Date
CH324470A CH489464A (de) 1966-09-22 1967-09-19 Verfahren zur Herstellung von neuen Amino-dihalogen-phenyläthylaminen
CH1309567A CH490319A (de) 1966-09-22 1967-09-19 Verfahren zur Herstellung von neuen Amino-dihalogen-phenyläthylaminen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH324470A CH489464A (de) 1966-09-22 1967-09-19 Verfahren zur Herstellung von neuen Amino-dihalogen-phenyläthylaminen

Country Status (14)

Country Link
US (1) US3536712A (de)
AT (8) AT277974B (de)
BE (1) BE704213A (de)
CH (2) CH489464A (de)
DE (2) DE1618005A1 (de)
DK (1) DK125417B (de)
ES (8) ES345210A1 (de)
FI (1) FI48460C (de)
FR (2) FR1544212A (de)
GB (1) GB1178191A (de)
IT (1) IT7949574A0 (de)
NL (1) NL6712787A (de)
SE (1) SE366539B (de)
YU (2) YU33283B (de)

Families Citing this family (63)

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US3929871A (en) * 1968-04-01 1975-12-30 Haessle Ab 1-(3-Hydroxy-4-alkyl-phenyl)-alkylamines(-2) and the salts thereof
DE2157040A1 (de) * 1971-11-17 1973-05-24 Thomae Gmbh Dr K Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen
AT324304B (de) * 1972-04-22 1975-08-25 Thomae Gmbh Dr K Verfahren zur herstellung von neuen 1-(4'-amino-3'-halogen-phenyl)-2-cycloalkylamino äthanolen
US4024281A (en) * 1972-05-26 1977-05-17 Smithkline Corporation N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines
DE2354961C2 (de) * 1973-11-02 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach Verfahren zur Herstellung von Aminophenyl-äthanolaminen
US4119710A (en) * 1972-12-18 1978-10-10 Boehringer Ingelheim Gmbh Bronchospasmolytic 1-(p-amino-phenyl)-2-amino-ethanols-(1) and salts
FR2281108A1 (fr) * 1974-08-06 1976-03-05 Ferrer Labor Medicaments constitues par de nouvelles dihalogene-acetamino-benzylamines et leur procede de fabrication
US3984421A (en) * 1975-05-08 1976-10-05 E. R. Squibb & Sons, Inc. Derivatives of [[(1-piperidinyl)ethyl]phenyl]alkanediamines
US4061778A (en) * 1975-06-20 1977-12-06 Sandoz, Inc. Iminodimethylene di-tert-alkylophenones and phenols
US4154761A (en) * 1976-02-09 1979-05-15 Allen & Hanburys Limited Pharmacologically active compounds
DE2861733D1 (en) * 1977-08-16 1982-05-27 Ici Plc Anti-inflammatory 1-phenylethanolamine derivatives, pharmaceutical compositions thereof and processes for their manufacture
US4754047A (en) * 1979-08-16 1988-06-28 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and/or improving the efficiency of feed utilization thereby
US4404222A (en) * 1980-08-25 1983-09-13 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby
IL60530A (en) * 1979-08-16 1984-10-31 American Cyanamid Co Animal feed compositions useful as growth promotors and for reduction of fat in animals,comprising phenylethanolamine derivatives and certain such novel compounds
ZA81947B (en) * 1980-08-25 1982-03-31 American Cyanamid Co 1-(aminodihalophenyl)-2-aminoethane derivatives for enhancing the growth and for the depression of fat in warm-blooded animals
US4407819A (en) * 1980-08-25 1983-10-04 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals
DE3175580D1 (en) * 1980-08-25 1987-01-02 American Cyanamid Co Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof
US4432995A (en) * 1980-12-22 1984-02-21 American Cyanamid Company 5-[2-(Ethylamino)-1-hydroxylethyl] anthranilonitrile and the use thereof in meat producing animals
DE3104850A1 (de) * 1981-02-11 1982-08-26 Dr. Karl Thomae Gmbh, 7950 Biberach "neuer futterzusatz zur verbesserung des wachstums"
US4906781A (en) * 1983-02-01 1990-03-06 American Cyanamid Company Method for the preparation of 4'-(substituted)-amino-2-(substituted) amino-3',5'-dichloroacetophenone and salts thereof
US4649158A (en) * 1983-02-01 1987-03-10 American Cyanamid Company Novel salts of 1-(aminodihalophenyl)-2-aminoethanols and antilipogenic compositions prepared therefrom
US4552897A (en) * 1983-02-01 1985-11-12 American Cyanamid Company Salts of 1-(aminodihalophenyl)-2-aminoethanols and antilipogenic compositions prepared therefrom
EP0146738B1 (de) * 1983-12-23 1990-12-19 American Cyanamid Company Antimikrobielle Tierfutterzusatzzusammensetzungen
FR2569184A1 (fr) * 1984-08-20 1986-02-21 Lafon Labor Derives de 1-(aminophenyl) therapeutique et leur procede de preparation
US5236922A (en) * 1984-08-20 1993-08-17 Laboratoire L. Lafon Method for treating depression using 1-(aminophenyl)-2-aminopropanone derivatives
US5250546A (en) * 1984-09-28 1993-10-05 Nippon Chemiphar Co., Ltd. Amino-alcohol derivatives and processes for their preparation
GB8525321D0 (en) * 1985-10-15 1985-11-20 Glaxo Group Ltd Chemical compounds
US4943591A (en) * 1984-10-17 1990-07-24 Glaxo Group Limited Dichloroaniline derivatives
ES537634A0 (es) * 1984-11-14 1985-09-16 Elmu Sa Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato
US5169633A (en) * 1985-07-29 1992-12-08 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
US5059422A (en) * 1985-07-29 1991-10-22 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
ATE61794T1 (de) * 1985-10-17 1991-04-15 American Cyanamid Co Anthranilonitrilderivate und verwandte verbindungen als nuetzliche stoffe zur wachstumsbeschleunigung, zur verbesserung der futterqualitaet und zur steigerung des fleisch/fett-verhaeltnisses bei warmbluetigen tieren.
US4863959A (en) * 1985-10-17 1989-09-05 American Cyanamid Company Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals
US4665095A (en) * 1985-12-11 1987-05-12 Abbott Laboratories Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion
GB8603475D0 (en) * 1986-02-12 1986-03-19 Glaxo Group Ltd Chemical compounds
GB8703007D0 (en) * 1987-02-10 1987-03-18 Glaxo Group Ltd Chemical compounds
DE3714484A1 (de) * 1987-04-30 1988-11-10 Bayer Ag Neue aminophenylethylamin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als leistungsfoerderer
US5149698A (en) * 1987-08-11 1992-09-22 Glaxo Group Limited Chloroaniline derivatives
US5198586A (en) * 1987-08-12 1993-03-30 Sanofi Process for the preparation of phenylethanolaminotetralins
US5530029A (en) * 1987-09-15 1996-06-25 The Rowett Research Institute Therapeutic applications of clenbuterol
US5552442A (en) * 1987-09-15 1996-09-03 The Rowett Research Institute Therapeutic applications of clenbuterol
FR2626878B1 (fr) * 1988-02-10 1990-06-08 Lafon Labor Derives de 1-(aminophenyl)-2-dimethylaminopropanone, procede de preparation et utilisation en therapeutique
US5453418A (en) * 1988-03-07 1995-09-26 Eli Lilly And Company Ractopamine and growth hormone combinations
IT1216120B (it) * 1988-03-17 1990-02-22 Poli Ind Chimica Spa Derivati n_cicloalchilaminoetilbenzamidici, loro preparazione e composizioni farmaceutiche che li contengono.
GB8909273D0 (en) * 1989-04-24 1989-06-07 Glaxo Group Ltd Chemical compounds
IT1230931B (it) * 1989-06-27 1991-11-08 Chiesi Farma Spa Derivati di 2 ammino 1,2,3,4 tetraidronaftalene ad attivita' cardiovascolare, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
FR2653767B1 (fr) * 1989-10-30 1992-02-14 Lafon Labor Derives de 1-(aminophenyl)-2-piperidinopropanone, procede et utilisation en therapeutique.
AP251A (en) * 1990-06-05 1993-04-20 Glaxo Group Ltd Dichloroaniline compound.
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
WO1994008945A1 (de) * 1992-10-16 1994-04-28 Byk Nederland Bv Substituierte ethanolaminester
UA55374C2 (uk) 1994-10-21 2003-04-15 Нпс Фармасьютікалз, Інк Сполуки, що мають активність по відношенню до рецепторів кальцію
ES2280460T3 (es) 1996-05-01 2007-09-16 Nps Pharmaceuticals, Inc. Compuestos activos frente a receptores de iones inorganicos.
US20030216423A1 (en) * 2000-05-24 2003-11-20 Sergio Ulloa Stable liquid and solid formulations
CA2575932A1 (en) * 2004-08-04 2006-02-16 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
EP1754474A1 (de) * 2005-02-02 2007-02-21 Eucro European Contract Research GmbH & Co. KG Verwendung von S-Clenbuterol
US20080014152A1 (en) * 2006-07-13 2008-01-17 Di Mauro Thomas M Intranasal delivery of clenbuterol across the cribriform plate and into the brain
AR077101A1 (es) 2009-06-16 2011-08-03 Schering Corp Esteroides de heteroarilo (3,2-c), como agonistas de receptor glucocorticoide, composiciones y usos de los mismos
DK2925725T3 (en) 2012-12-03 2017-01-16 Pfizer androgen receptor modulators
EP3331848A4 (de) 2015-08-06 2019-07-17 Vamsi Labs Ltd. Verfahren zur herstellung von beta-agonisten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE626435A (de) * 1961-12-22
GB1121857A (en) * 1965-01-05 1968-07-31 Science Union & Cie New phenylisopropylamine derivatives and process for their preparation and pharmaceutical preparations of such derivatives

Also Published As

Publication number Publication date
AT277974B (de) 1970-01-12
DE1618009A1 (de) 1971-04-29
FR1544212A (fr) 1968-10-31
GB1178191A (en) 1970-01-21
ES345819A1 (es) 1969-03-16
AT277971B (de) 1970-01-12
AT277972B (de) 1970-01-12
CH489464A (de) 1970-04-30
AT277976B (de) 1970-01-12
ES345210A1 (es) 1969-01-01
DE1618005A1 (de) 1971-09-09
FI48460B (de) 1974-07-01
FR6923M (de) 1969-05-05
ES345686A1 (es) 1969-01-16
DE1543928A1 (de) 1970-01-29
AT277210B (de) 1969-12-10
YU33114B (en) 1976-04-30
FI48460C (fi) 1974-10-10
DK125417B (da) 1973-02-19
YU184167A (en) 1976-03-31
ES345820A1 (es) 1969-11-01
IT7949574A0 (it) 1979-06-28
YU100574A (en) 1975-10-31
SE366539B (de) 1974-04-29
YU33283B (en) 1976-08-31
NL6712787A (de) 1968-03-25
BE704213A (de) 1968-03-22
ES345817A1 (es) 1969-01-01
AT277973B (de) 1970-01-12
ES345818A1 (es) 1969-05-16
ES345685A1 (es) 1969-03-16
ES345318A1 (es) 1969-01-01
AT277975B (de) 1970-01-12
AT280997B (de) 1970-05-11
US3536712A (en) 1970-10-27

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Legal Events

Date Code Title Description
PL Patent ceased