ES345818A1 - Un procedimiento para la obtencion de nuevas amino-dihalo- geno-fenil-etilaminas. - Google Patents

Un procedimiento para la obtencion de nuevas amino-dihalo- geno-fenil-etilaminas.

Info

Publication number
ES345818A1
ES345818A1 ES345818A ES345818A ES345818A1 ES 345818 A1 ES345818 A1 ES 345818A1 ES 345818 A ES345818 A ES 345818A ES 345818 A ES345818 A ES 345818A ES 345818 A1 ES345818 A1 ES 345818A1
Authority
ES
Spain
Prior art keywords
general formula
reduction
atom
hydroxyl group
hydrogen atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES345818A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES345818A1 publication Critical patent/ES345818A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES345818A 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- geno-fenil-etilaminas. Expired ES345818A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DET0032111 1966-09-22
DET0033217 1967-02-15
DET0034019 1967-06-02

Publications (1)

Publication Number Publication Date
ES345818A1 true ES345818A1 (es) 1969-05-16

Family

ID=27213171

Family Applications (8)

Application Number Title Priority Date Filing Date
ES345210A Expired ES345210A1 (es) 1966-09-22 1967-09-19 Procedimiento para la obtencion de nuevas amino-dihalogeno - fenil -etil-aminas.
ES345318A Expired ES345318A1 (es) 1966-09-22 1967-09-22 Procedimiento para la obtencion de nuevas amino - dihaloge-nofenil - etilaminas.
ES345685A Expired ES345685A1 (es) 1966-09-22 1967-10-03 Procedimiento para la obtencion de nuevas dihalogeno-fenil-etilaminas.
ES345686A Expired ES345686A1 (es) 1966-09-22 1967-10-03 Procedimiento para la obtencion de nuevas amino - dihaloge-no - fenil-etilaminas.
ES345820A Expired ES345820A1 (es) 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- geno-feniletilaminas.
ES345819A Expired ES345819A1 (es) 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- genofenil-etilaminas.
ES345818A Expired ES345818A1 (es) 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- geno-fenil-etilaminas.
ES345817A Expired ES345817A1 (es) 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- feno - fenil-etilaminas.

Family Applications Before (6)

Application Number Title Priority Date Filing Date
ES345210A Expired ES345210A1 (es) 1966-09-22 1967-09-19 Procedimiento para la obtencion de nuevas amino-dihalogeno - fenil -etil-aminas.
ES345318A Expired ES345318A1 (es) 1966-09-22 1967-09-22 Procedimiento para la obtencion de nuevas amino - dihaloge-nofenil - etilaminas.
ES345685A Expired ES345685A1 (es) 1966-09-22 1967-10-03 Procedimiento para la obtencion de nuevas dihalogeno-fenil-etilaminas.
ES345686A Expired ES345686A1 (es) 1966-09-22 1967-10-03 Procedimiento para la obtencion de nuevas amino - dihaloge-no - fenil-etilaminas.
ES345820A Expired ES345820A1 (es) 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- geno-feniletilaminas.
ES345819A Expired ES345819A1 (es) 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- genofenil-etilaminas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES345817A Expired ES345817A1 (es) 1966-09-22 1967-10-06 Un procedimiento para la obtencion de nuevas amino-dihalo- feno - fenil-etilaminas.

Country Status (14)

Country Link
US (1) US3536712A (es)
AT (8) AT277973B (es)
BE (1) BE704213A (es)
CH (2) CH490319A (es)
DE (2) DE1618005A1 (es)
DK (1) DK125417B (es)
ES (8) ES345210A1 (es)
FI (1) FI48460C (es)
FR (2) FR1544212A (es)
GB (1) GB1178191A (es)
IT (1) IT7949574A0 (es)
NL (1) NL6712787A (es)
SE (1) SE366539B (es)
YU (2) YU33283B (es)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862987A (en) * 1966-10-18 1975-01-28 Delmar Chem Phenyl-hydroxypropyl-substituted 1-amino adamantanes
US3929871A (en) * 1968-04-01 1975-12-30 Haessle Ab 1-(3-Hydroxy-4-alkyl-phenyl)-alkylamines(-2) and the salts thereof
DE2157040A1 (de) * 1971-11-17 1973-05-24 Thomae Gmbh Dr K Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen
AT326634B (de) * 1972-04-22 1975-12-29 Thomae Gmbh Dr K Verfahren zur herstellung von neuen 1-(4'-amino-3',5'-dihalogenphenyl)-2-cycloalkylaminoathanolen
US4024281A (en) * 1972-05-26 1977-05-17 Smithkline Corporation N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines
DE2354961C2 (de) * 1973-11-02 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach Verfahren zur Herstellung von Aminophenyl-äthanolaminen
US4119710A (en) * 1972-12-18 1978-10-10 Boehringer Ingelheim Gmbh Bronchospasmolytic 1-(p-amino-phenyl)-2-amino-ethanols-(1) and salts
FR2281108A1 (fr) * 1974-08-06 1976-03-05 Ferrer Labor Medicaments constitues par de nouvelles dihalogene-acetamino-benzylamines et leur procede de fabrication
US3984421A (en) * 1975-05-08 1976-10-05 E. R. Squibb & Sons, Inc. Derivatives of [[(1-piperidinyl)ethyl]phenyl]alkanediamines
US4061778A (en) * 1975-06-20 1977-12-06 Sandoz, Inc. Iminodimethylene di-tert-alkylophenones and phenols
US4154761A (en) * 1976-02-09 1979-05-15 Allen & Hanburys Limited Pharmacologically active compounds
DE2861733D1 (en) * 1977-08-16 1982-05-27 Ici Plc Anti-inflammatory 1-phenylethanolamine derivatives, pharmaceutical compositions thereof and processes for their manufacture
IL60530A (en) * 1979-08-16 1984-10-31 American Cyanamid Co Animal feed compositions useful as growth promotors and for reduction of fat in animals,comprising phenylethanolamine derivatives and certain such novel compounds
US4754047A (en) * 1979-08-16 1988-06-28 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and/or improving the efficiency of feed utilization thereby
US4404222A (en) * 1980-08-25 1983-09-13 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby
EP0049728B1 (en) * 1980-08-25 1986-11-12 American Cyanamid Company Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof
US4407819A (en) * 1980-08-25 1983-10-04 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals
ZA81947B (en) * 1980-08-25 1982-03-31 American Cyanamid Co 1-(aminodihalophenyl)-2-aminoethane derivatives for enhancing the growth and for the depression of fat in warm-blooded animals
US4432995A (en) * 1980-12-22 1984-02-21 American Cyanamid Company 5-[2-(Ethylamino)-1-hydroxylethyl] anthranilonitrile and the use thereof in meat producing animals
DE3104850A1 (de) * 1981-02-11 1982-08-26 Dr. Karl Thomae Gmbh, 7950 Biberach "neuer futterzusatz zur verbesserung des wachstums"
US4649158A (en) * 1983-02-01 1987-03-10 American Cyanamid Company Novel salts of 1-(aminodihalophenyl)-2-aminoethanols and antilipogenic compositions prepared therefrom
US4552897A (en) * 1983-02-01 1985-11-12 American Cyanamid Company Salts of 1-(aminodihalophenyl)-2-aminoethanols and antilipogenic compositions prepared therefrom
US4906781A (en) * 1983-02-01 1990-03-06 American Cyanamid Company Method for the preparation of 4'-(substituted)-amino-2-(substituted) amino-3',5'-dichloroacetophenone and salts thereof
ATE59134T1 (de) * 1983-12-23 1991-01-15 American Cyanamid Co Antimikrobielle tierfutterzusatzzusammensetzungen.
US5236922A (en) * 1984-08-20 1993-08-17 Laboratoire L. Lafon Method for treating depression using 1-(aminophenyl)-2-aminopropanone derivatives
FR2569184A1 (fr) * 1984-08-20 1986-02-21 Lafon Labor Derives de 1-(aminophenyl) therapeutique et leur procede de preparation
US5250546A (en) * 1984-09-28 1993-10-05 Nippon Chemiphar Co., Ltd. Amino-alcohol derivatives and processes for their preparation
US4943591A (en) * 1984-10-17 1990-07-24 Glaxo Group Limited Dichloroaniline derivatives
GB8525321D0 (en) * 1985-10-15 1985-11-20 Glaxo Group Ltd Chemical compounds
ES537634A0 (es) * 1984-11-14 1985-09-16 Elmu Sa Procedimiento de obtencion de -(((2-hidroxi-1, 1-dimetil-etil)-amino)metil), benceno-metanol clorhidrato
US5059422A (en) * 1985-07-29 1991-10-22 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
US5169633A (en) * 1985-07-29 1992-12-08 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
DE3678252D1 (de) * 1985-10-17 1991-04-25 American Cyanamid Co Anthranilonitrilderivate und verwandte verbindungen als nuetzliche stoffe zur wachstumsbeschleunigung, zur verbesserung der futterqualitaet und zur steigerung des fleisch/fett-verhaeltnisses bei warmbluetigen tieren.
US4863959A (en) * 1985-10-17 1989-09-05 American Cyanamid Company Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals
US4665095A (en) * 1985-12-11 1987-05-12 Abbott Laboratories Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion
GB8603475D0 (en) * 1986-02-12 1986-03-19 Glaxo Group Ltd Chemical compounds
GB8703007D0 (en) * 1987-02-10 1987-03-18 Glaxo Group Ltd Chemical compounds
DE3714484A1 (de) * 1987-04-30 1988-11-10 Bayer Ag Neue aminophenylethylamin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als leistungsfoerderer
US5149698A (en) * 1987-08-11 1992-09-22 Glaxo Group Limited Chloroaniline derivatives
US5198586A (en) * 1987-08-12 1993-03-30 Sanofi Process for the preparation of phenylethanolaminotetralins
US5552442A (en) * 1987-09-15 1996-09-03 The Rowett Research Institute Therapeutic applications of clenbuterol
US5530029A (en) * 1987-09-15 1996-06-25 The Rowett Research Institute Therapeutic applications of clenbuterol
FR2626878B1 (fr) * 1988-02-10 1990-06-08 Lafon Labor Derives de 1-(aminophenyl)-2-dimethylaminopropanone, procede de preparation et utilisation en therapeutique
US5453418A (en) * 1988-03-07 1995-09-26 Eli Lilly And Company Ractopamine and growth hormone combinations
IT1216120B (it) * 1988-03-17 1990-02-22 Poli Ind Chimica Spa Derivati n_cicloalchilaminoetilbenzamidici, loro preparazione e composizioni farmaceutiche che li contengono.
GB8909273D0 (en) * 1989-04-24 1989-06-07 Glaxo Group Ltd Chemical compounds
IT1230931B (it) * 1989-06-27 1991-11-08 Chiesi Farma Spa Derivati di 2 ammino 1,2,3,4 tetraidronaftalene ad attivita' cardiovascolare, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
FR2653767B1 (fr) * 1989-10-30 1992-02-14 Lafon Labor Derives de 1-(aminophenyl)-2-piperidinopropanone, procede et utilisation en therapeutique.
LU87945A1 (fr) * 1990-06-05 1993-01-15 Glaxo Group Ltd Derive de la dichloroaniline
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
EP0664788A1 (de) * 1992-10-16 1995-08-02 Byk Nederland BV Substituierte ethanolaminester
ES2234768T3 (es) 1994-10-21 2005-07-01 Nps Pharmaceuticals, Inc. Compuestos capaces de modular la actividad del receptor de calcio.
ES2326004T3 (es) 1996-05-01 2009-09-28 Nps Pharmaceuticals, Inc. Compuestos activos de receptor de ion inorganico.
US20030216423A1 (en) * 2000-05-24 2003-11-20 Sergio Ulloa Stable liquid and solid formulations
WO2006017505A2 (en) * 2004-08-04 2006-02-16 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
EP1754474A1 (en) * 2005-02-02 2007-02-21 Eucro European Contract Research GmbH & Co. KG Use of S-Clenbuterol
US20080014152A1 (en) * 2006-07-13 2008-01-17 Di Mauro Thomas M Intranasal delivery of clenbuterol across the cribriform plate and into the brain
CN102834406A (zh) 2009-06-16 2012-12-19 默沙东公司 作为糖皮质激素受体激动剂的新的[3.2-c]杂芳基甾体、其组合物和用途
DK2925725T3 (en) 2012-12-03 2017-01-16 Pfizer androgen receptor modulators
EP3331848A4 (en) 2015-08-06 2019-07-17 Vamsi Labs Ltd. PROCESS FOR THE PREPARATION OF BETA AGONISTS

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL287142A (es) * 1961-12-22
GB1121857A (en) * 1965-01-05 1968-07-31 Science Union & Cie New phenylisopropylamine derivatives and process for their preparation and pharmaceutical preparations of such derivatives

Also Published As

Publication number Publication date
AT277210B (de) 1969-12-10
DE1618005A1 (de) 1971-09-09
ES345210A1 (es) 1969-01-01
DK125417B (da) 1973-02-19
YU100574A (en) 1975-10-31
YU33114B (en) 1976-04-30
AT277974B (de) 1970-01-12
FI48460B (es) 1974-07-01
DE1543928A1 (de) 1970-01-29
FR1544212A (fr) 1968-10-31
NL6712787A (es) 1968-03-25
ES345820A1 (es) 1969-11-01
YU33283B (en) 1976-08-31
AT277972B (de) 1970-01-12
CH489464A (de) 1970-04-30
ES345318A1 (es) 1969-01-01
IT7949574A0 (it) 1979-06-28
FI48460C (fi) 1974-10-10
AT277971B (de) 1970-01-12
ES345819A1 (es) 1969-03-16
ES345817A1 (es) 1969-01-01
CH490319A (de) 1970-05-15
AT277976B (de) 1970-01-12
AT277975B (de) 1970-01-12
FR6923M (es) 1969-05-05
SE366539B (es) 1974-04-29
ES345686A1 (es) 1969-01-16
AT277973B (de) 1970-01-12
ES345685A1 (es) 1969-03-16
YU184167A (en) 1976-03-31
BE704213A (es) 1968-03-22
GB1178191A (en) 1970-01-21
US3536712A (en) 1970-10-27
AT280997B (de) 1970-05-11
DE1618009A1 (de) 1971-04-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19890102