CH495348A - Verfahren zur Herstellung von a-Oxo-a, B-seco-steroid-B(y)-inen - Google Patents

Verfahren zur Herstellung von a-Oxo-a, B-seco-steroid-B(y)-inen

Info

Publication number
CH495348A
CH495348A CH1847766A CH1847766A CH495348A CH 495348 A CH495348 A CH 495348A CH 1847766 A CH1847766 A CH 1847766A CH 1847766 A CH1847766 A CH 1847766A CH 495348 A CH495348 A CH 495348A
Authority
CH
Switzerland
Prior art keywords
ynes
seco
steroid
oxo
preparation
Prior art date
Application number
CH1847766A
Other languages
English (en)
Inventor
Eschenmoser Albert Dr Prof
Original Assignee
Eschenmoser Albert Dr Prof
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH1581566A priority Critical patent/CH482637A/de
Application filed by Eschenmoser Albert Dr Prof filed Critical Eschenmoser Albert Dr Prof
Priority to CH1847766A priority patent/CH495348A/de
Priority to CH202567A priority patent/CH521297A/de
Priority to CH202667A priority patent/CH542193A/de
Priority to DE19671643948 priority patent/DE1643948A1/de
Priority to BE705698D priority patent/BE705698A/xx
Priority to FR1577241D priority patent/FR1577241A/fr
Priority to NL6714663A priority patent/NL6714663A/xx
Priority to GB49203/67A priority patent/GB1211697A/en
Priority to JP42069558A priority patent/JPS4818214B1/ja
Priority to ES346571A priority patent/ES346571A1/es
Publication of CH495348A publication Critical patent/CH495348A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C13/00—Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
    • C07C13/02—Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C07C29/175—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds with simultaneous reduction of an oxo group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/02—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains containing only carbon and hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/32—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen
    • C07C45/33—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen of CHx-moieties
    • C07C45/34—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen of CHx-moieties in unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/40—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with ozone; by ozonolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/32—All rings being cycloaliphatic the ring system containing at least eleven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1847766A 1966-11-01 1966-12-23 Verfahren zur Herstellung von a-Oxo-a, B-seco-steroid-B(y)-inen CH495348A (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CH1581566A CH482637A (de) 1966-11-01 1966-11-01 Verfahren zur Herstellung von Acetylenverbindungen
CH1847766A CH495348A (de) 1966-11-01 1966-12-23 Verfahren zur Herstellung von a-Oxo-a, B-seco-steroid-B(y)-inen
CH202567A CH521297A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Acetylenverbindungen
CH202667A CH542193A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Secosteroiden
DE19671643948 DE1643948A1 (de) 1966-11-01 1967-10-21 Verfahren zur Herstellung von Acetylenverbindungen
BE705698D BE705698A (de) 1966-11-01 1967-10-26
FR1577241D FR1577241A (de) 1966-11-01 1967-10-26
NL6714663A NL6714663A (de) 1966-11-01 1967-10-27
GB49203/67A GB1211697A (en) 1966-11-01 1967-10-30 Method for preparing acetylenic compounds
JP42069558A JPS4818214B1 (de) 1966-11-01 1967-10-30
ES346571A ES346571A1 (es) 1966-11-01 1967-10-30 Procedimiento para la obtencion de compuestos alfa-oxo-al- fa, beta-seco-beta (gamma)-acetileno.

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH1581566A CH482637A (de) 1966-11-01 1966-11-01 Verfahren zur Herstellung von Acetylenverbindungen
CH1847766A CH495348A (de) 1966-11-01 1966-12-23 Verfahren zur Herstellung von a-Oxo-a, B-seco-steroid-B(y)-inen
CH202567A CH521297A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Acetylenverbindungen
CH202667A CH542193A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Secosteroiden
CH342467 1967-03-09

Publications (1)

Publication Number Publication Date
CH495348A true CH495348A (de) 1970-08-31

Family

ID=27509031

Family Applications (4)

Application Number Title Priority Date Filing Date
CH1581566A CH482637A (de) 1966-11-01 1966-11-01 Verfahren zur Herstellung von Acetylenverbindungen
CH1847766A CH495348A (de) 1966-11-01 1966-12-23 Verfahren zur Herstellung von a-Oxo-a, B-seco-steroid-B(y)-inen
CH202567A CH521297A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Acetylenverbindungen
CH202667A CH542193A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Secosteroiden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1581566A CH482637A (de) 1966-11-01 1966-11-01 Verfahren zur Herstellung von Acetylenverbindungen

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH202567A CH521297A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Acetylenverbindungen
CH202667A CH542193A (de) 1966-11-01 1967-02-10 Verfahren zur Herstellung von Secosteroiden

Country Status (7)

Country Link
JP (1) JPS4818214B1 (de)
BE (1) BE705698A (de)
CH (4) CH482637A (de)
DE (1) DE1643948A1 (de)
FR (1) FR1577241A (de)
GB (1) GB1211697A (de)
NL (1) NL6714663A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50140727U (de) * 1974-05-08 1975-11-19
US4052422A (en) * 1974-11-08 1977-10-04 E. R. Squibb & Sons, Inc. 4,5-secopregnane derivatives
US4127589A (en) 1974-11-08 1978-11-28 E. R. Squibb & Sons, Inc. 4,5-Seco-steroids
JPS5175340U (de) * 1974-12-10 1976-06-14
NL185194C (nl) * 1976-07-27 1990-02-16 Naarden International Nv Werkwijze voor de bereiding van reukstofcomposities, alsmede werkwijze voor de bereiding van een reukstof.
US4328383A (en) * 1980-01-18 1982-05-04 S. A. Firmenich Process for preparing unsaturated bicyclic hydrocarbons
WO2005077875A1 (en) 2004-02-16 2005-08-25 Firmenich Sa A process for the preparation of optically active cyclohexenones
WO2016193330A1 (en) * 2015-06-03 2016-12-08 Basf Se Process for preparing 3-methylcyclopentadecane-1,5-dione

Also Published As

Publication number Publication date
DE1643948A1 (de) 1972-06-08
CH521297A (de) 1972-04-15
BE705698A (de) 1968-03-01
FR1577241A (de) 1969-08-08
CH482637A (de) 1969-12-15
NL6714663A (de) 1968-05-02
CH542193A (de) 1973-11-15
JPS4818214B1 (de) 1973-06-04
GB1211697A (en) 1970-11-11

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