AR247326A1 - Una composicion hipotonica acuosa para lentes de contacto. - Google Patents
Una composicion hipotonica acuosa para lentes de contacto.Info
- Publication number
- AR247326A1 AR247326A1 AR89314940A AR31494089A AR247326A1 AR 247326 A1 AR247326 A1 AR 247326A1 AR 89314940 A AR89314940 A AR 89314940A AR 31494089 A AR31494089 A AR 31494089A AR 247326 A1 AR247326 A1 AR 247326A1
- Authority
- AR
- Argentina
- Prior art keywords
- contact lens
- lens care
- aqueous antimicrobial
- antimicrobial solutions
- antimicrobial agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/143—Quaternary ammonium compounds
- A61L12/145—Polymeric quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2086—Hydroxy carboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3723—Polyamines or polyalkyleneimines
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Eyeglasses (AREA)
- Medicinal Preparation (AREA)
Abstract
COMPOSICION HIPOTONICA ACUOSA PARA LENTES DE CONTACTO, QUE COMPRENDE UNA CANTIDAD EFECTIVA DE UN AGENTE ANTIMICROBIANO CATIONICO, Y UNA CANTIDAD EFECTIVA DE UN AGENTE COMPLEJANTE (COMO COMPONENTE CAPAZ DE EVITAR LA FIJACION DEL AGENTE ANTIMICROBIANO A LOS LENTES HIDROFILICOS Y DE REDUCIR A LOS LENTES HIDROFILICOS LA TONICIDAD A UNA ESCALA SUFICIENTE PARA MANTENER ACTIVIDAD ANTIMICROBIANA EFICAZ); EL AGENTE ANTIMICROBIANO CATIONICO ES UN AGENTE ANTIMICROBIANO CUATERNARIO DE AMONIO Y LA COMPOSICION TIENE UNA OSMOLALIDAD DE 210 A 240 MOSM/KG.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/244,974 US5037647A (en) | 1988-09-15 | 1988-09-15 | Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride |
Publications (1)
Publication Number | Publication Date |
---|---|
AR247326A1 true AR247326A1 (es) | 1994-12-29 |
Family
ID=22924837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR89314940A AR247326A1 (es) | 1988-09-15 | 1989-09-15 | Una composicion hipotonica acuosa para lentes de contacto. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5037647A (es) |
EP (1) | EP0359574B1 (es) |
JP (1) | JPH0649060B2 (es) |
AR (1) | AR247326A1 (es) |
AT (1) | ATE182081T1 (es) |
AU (1) | AU625099B2 (es) |
CA (1) | CA1334573C (es) |
DE (1) | DE68929031T2 (es) |
DK (1) | DK175224B1 (es) |
ES (1) | ES2136055T3 (es) |
FI (1) | FI105321B (es) |
GR (1) | GR3031328T3 (es) |
HK (1) | HK1011941A1 (es) |
MX (1) | MX168660B (es) |
NZ (1) | NZ230663A (es) |
PH (1) | PH26017A (es) |
WO (1) | WO1990002555A1 (es) |
ZA (1) | ZA897060B (es) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0349487A3 (en) * | 1988-06-28 | 1990-07-04 | Ciba-Geigy Ag | Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2-phenoxyethyl)-ammonium bromide and methods of using the same |
US6051611A (en) * | 1991-11-08 | 2000-04-18 | Alcon Laboratories, Inc. | Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobias |
US5512597A (en) * | 1991-11-08 | 1996-04-30 | Alcon Laboratories, Inc. | Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials |
US5547663A (en) * | 1991-11-08 | 1996-08-20 | Alcon Laboratories, Inc. | Absolute molecular weight polymers and methods for their use |
EP0542686A1 (en) * | 1991-11-13 | 1993-05-19 | Ciba-Geigy Ag | Method and container for sterilizing or disinfecting |
US5256420A (en) * | 1991-12-23 | 1993-10-26 | Ciba-Geigy Corporation | Method of imparting antimicrobial acitivity to an ophthalmic composition |
US5356555A (en) * | 1992-09-14 | 1994-10-18 | Allergan, Inc. | Non-oxidative method and composition for simultaneously cleaning and disinfecting contact lenses using a protease with a disinfectant |
AU5417501A (en) * | 1993-08-27 | 2001-09-20 | Alcon Laboratories, Inc. | Process for cleaning and disinfecting contact lenses |
US5370744B1 (en) * | 1993-08-27 | 1999-11-09 | Alcon Lab Inc | Process for cleaning and disinfecting contact lenses |
AU733386B2 (en) * | 1993-08-27 | 2001-05-10 | Alcon Laboratories, Inc. | Process for cleaning and disinfecting contact lenses |
US5382599A (en) * | 1993-10-13 | 1995-01-17 | Allergan, Inc. | Method of inhibiting protozoan growth in eye care products using a polyvalent cation chelating agent |
US5536494A (en) * | 1994-10-04 | 1996-07-16 | Alcon Laboratories, Inc. | Polyethylene oxide-containing quaternary ammunium polymers and pharmaceutical compositions containing an antimicrobial amount of same |
US5603929A (en) * | 1994-11-16 | 1997-02-18 | Alcon Laboratories, Inc. | Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds |
AU1180300A (en) * | 1998-11-16 | 2000-06-05 | Rohto Pharmaceutical Co., Ltd. | Liquid ophthalmic preparations |
US6790816B2 (en) | 1999-09-24 | 2004-09-14 | Bausch & Lomb Incorporated | High osmolyte cleaning and disinfection method and solution for contact lenses |
WO2001054687A1 (en) * | 2000-01-25 | 2001-08-02 | Alcon Universal Ltd. | Ophthalmic anti-allergy compositions suitable for use with contact lenses |
US20020183233A1 (en) * | 2000-12-14 | 2002-12-05 | The Clorox Company, Delaware Corporation | Bactericidal cleaning wipe |
US7799751B2 (en) * | 2000-12-14 | 2010-09-21 | The Clorox Company | Cleaning composition |
US20030100465A1 (en) * | 2000-12-14 | 2003-05-29 | The Clorox Company, A Delaware Corporation | Cleaning composition |
DE10137978A1 (de) * | 2001-08-02 | 2003-02-13 | Creavis Tech & Innovation Gmbh | Antimikrobielle Reinigungsmittel |
JP4255656B2 (ja) * | 2001-09-17 | 2009-04-15 | 株式会社メニコン | 眼科用液剤及びコンタクトレンズ用液剤 |
US20040028645A1 (en) * | 2001-12-13 | 2004-02-12 | Masood Chowhan | Artificial tear composition adapted to be used with contact lenses |
BR0215176A (pt) * | 2001-12-21 | 2004-11-30 | Alcon Inc | Uso de nanopartìculas como veìculos para biocidas em composições oftálmicas |
MXPA04004915A (es) * | 2001-12-21 | 2004-08-11 | Alcon Inc | Nanoparticulas inorganicas para modificar la viscosidad y las propiedades fisicas de composiciones oftalmicas y oticas. |
JP2005514429A (ja) * | 2001-12-21 | 2005-05-19 | アルコン、インコーポレイテッド | 眼/耳用薬物のキャリヤーとしての合成無機質ナノ粒子の使用 |
US20060276359A1 (en) * | 2005-06-03 | 2006-12-07 | Bausch & Lomb Incorporated | Composition and method for cleaning lipid deposits on contact lenses |
US7282178B2 (en) * | 2005-06-03 | 2007-10-16 | Bausch & Lomb Incorporated | Composition and method for cleaning lipid deposits on contact lenses |
US20060275173A1 (en) * | 2005-06-03 | 2006-12-07 | Bausch & Lomb Incorporated | Method for cleaning lipid deposits on silicone hydrogel contact lenses |
JP5135526B2 (ja) * | 2005-06-27 | 2013-02-06 | 株式会社メニコンネクト | コンタクトレンズ用液剤 |
US20070053948A1 (en) * | 2005-09-08 | 2007-03-08 | Bausch & Lomb Incorporated | Lens care solution demonstration kit |
TWI434926B (zh) * | 2006-12-11 | 2014-04-21 | Alcon Res Ltd | 眼用組成物中聚氧化乙烯-聚氧化丁烯(peo-pbo)嵌段共聚物之使用 |
US8227017B2 (en) * | 2007-11-13 | 2012-07-24 | Quick-Med Technologies, Inc. | System and method for enhancing the efficacy of antimicrobial contact lenses and other surfaces |
TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
KR101541303B1 (ko) | 2008-03-17 | 2015-08-03 | 알콘 리서치, 리미티드 | 보레이트-폴리올 복합체를 함유하는 수성 약학적 조성물 |
KR20110025760A (ko) * | 2008-05-19 | 2011-03-11 | 알콘 리서치, 리미티드 | 카복시비닐 폴리머 및 포비돈 폴리머를 포함하는 약제학적 조성물 |
TW201023912A (en) * | 2008-12-05 | 2010-07-01 | Alcon Res Ltd | Pharmaceutical suspension |
US8431751B1 (en) | 2008-12-24 | 2013-04-30 | Alcon Research, Ltd. | Polymeric quaternary ammonium compounds with vicinal hydroxy groups |
CA2753837A1 (en) * | 2009-03-03 | 2010-09-10 | Alcon Research, Ltd. | Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (rtki) compounds to the eye |
US8912236B2 (en) * | 2009-03-03 | 2014-12-16 | Alcon Research, Ltd. | Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye |
TW201038295A (en) * | 2009-04-17 | 2010-11-01 | Alcon Res Ltd | Aqueous ophthalmic compositions containing anionic therapeutic agents |
TWI489997B (zh) * | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸-多元醇錯合物之水性藥學組成物 |
TWI547522B (zh) * | 2009-07-07 | 2016-09-01 | 愛爾康研究有限公司 | 環氧乙烷環氧丁烷嵌段共聚物組成物 |
TWI478730B (zh) | 2009-12-03 | 2015-04-01 | Alcon Res Ltd | 眼科乳劑 |
US8999312B2 (en) | 2010-06-02 | 2015-04-07 | Alcon Research, Ltd. | Use of PBO-PEO-PBO block copolymers in ophthalmic compositions |
CA2833596A1 (en) | 2011-04-22 | 2012-10-26 | Alcon Research, Ltd. | Ophthalmic composition with a viscosity enhancement system having two different viscosity enhancing agents |
RU2013152013A (ru) | 2011-04-22 | 2015-05-27 | Алькон Рисерч, Лтд. | Офтальмологическая композиция с системой увеличения вязкости, имеющей два различных увеличивающих вязкость агента |
TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠(olopatadine)眼用組成物 |
TW201336527A (zh) | 2012-02-10 | 2013-09-16 | Alcon Res Ltd | 具增強的穩定性之水性藥學組成物 |
WO2014058402A2 (en) * | 2012-10-12 | 2014-04-17 | Alke Saglik Urunleri Sanayi Ve Ticaret Anonim Sirketi | Liquid cip (clean-in-place) detergent combinations |
US10174006B2 (en) | 2013-06-06 | 2019-01-08 | Novartis Ag | Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease |
HUE038809T2 (hu) | 2013-12-17 | 2018-11-28 | Novartis Ag | Térhálósított hidrofíl bevonattal ellátott szilikon hidrogél lencse |
WO2017022781A1 (ja) * | 2015-08-03 | 2017-02-09 | 花王株式会社 | 抗菌型衣料用液体洗浄剤組成物 |
EP3436467A4 (en) | 2016-03-30 | 2020-03-18 | Ayuvis Research, Inc. | NEW COMPOSITIONS AND THERAPEUTIC METHODS |
TW201938141A (zh) | 2018-02-21 | 2019-10-01 | 瑞士商諾華公司 | 基於脂質的眼用乳劑 |
WO2020010090A1 (en) | 2018-07-02 | 2020-01-09 | Ayuvis Research, Inc. | Novel immunodulating small molecules |
EP4431497A1 (en) | 2019-02-15 | 2024-09-18 | Bausch + Lomb Ireland Limited | Crystalline forms of 4-(7-hydroxy-2-isopropyl-4-oxo-4h-quinazolin-3-yl)-benzonitrile and formulations thereof |
JP6994061B2 (ja) | 2019-02-15 | 2022-01-14 | ノバルティス アーゲー | 4-(7-ヒドロキシ-2-イソプロピル-4-オキソ-4h-キナゾリン-3-イル)-ベンゾニトリルの製剤 |
JP2023536938A (ja) | 2020-08-06 | 2023-08-30 | ノバルティス アーゲー | 4-(7-ヒドロキシ-2-イソプロピル-4-オキソ-4h-キナゾリン-3-イル)-ベンゾニトリルの結晶形態及びその製剤 |
CN113088411A (zh) * | 2021-04-08 | 2021-07-09 | 山西利普达医药科技有限公司 | 一种含聚季铵盐-1的眼用清洗灭活病毒组合物及其应用 |
WO2024062389A1 (en) | 2022-09-21 | 2024-03-28 | Bausch + Lomb Ireland Limited | Crystalline polymorph forms of a trpv1 antagonist and formulations thereof |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US440771A (en) * | 1890-11-18 | Oil-cup | ||
DE2930865A1 (de) * | 1979-07-30 | 1981-02-12 | Schuelke & Mayr Gmbh | Desinfektions- und konservierungsmittel |
US4499077A (en) * | 1981-02-03 | 1985-02-12 | Stockel Richard F | Anti-microbial compositions and associated methods for preparing the same and for the disinfecting of various objects |
US4407791A (en) * | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
US4525346A (en) * | 1981-09-28 | 1985-06-25 | Alcon Laboratories, Inc. | Aqueous antimicrobial ophthalmic solutions |
EP0145710A1 (en) * | 1983-05-25 | 1985-06-26 | Alcon Laboratories, Inc. | Ophthalmic solution |
US4579960A (en) * | 1984-05-07 | 1986-04-01 | Schering Corporation | Stable solutions containing thimerosal |
CA1259542A (en) * | 1984-09-28 | 1989-09-19 | Francis X. Smith | Disinfecting and preserving solutions for contact lenses and methods of use |
US4599195A (en) * | 1984-12-28 | 1986-07-08 | Alcon Laboratories, Inc. | Solution and method for removing protein, lipid, and calcium deposits from contact lenses |
ATE49887T1 (de) * | 1985-07-22 | 1990-02-15 | Bausch & Lomb | Verfahren und loesung zur desinfektion und konservierung von kontaktlinsen. |
AU6898887A (en) * | 1986-01-06 | 1987-07-28 | Allergan, Inc. | Enhancement of enzymatic activity in cleaning contact lenses by the use of hypotonic solutions |
US4734222A (en) * | 1986-04-03 | 1988-03-29 | Ciba-Geigy Corporation | Composition and method for cleaning soft and hard contact lenses |
GB8625103D0 (en) * | 1986-10-20 | 1986-11-26 | Unilever Plc | Disinfectant compositions |
JPH01501899A (ja) * | 1986-12-24 | 1989-06-29 | アルコン ラボラトリーズ インコーポレイテッド | コンタクトレンズ用洗浄剤及びその使用方法 |
ES2053161T3 (es) * | 1989-09-21 | 1994-07-16 | Ciba Vision Ag | Composiciones antimicrobianas. |
-
1988
- 1988-09-15 US US07/244,974 patent/US5037647A/en not_active Expired - Lifetime
-
1989
- 1989-09-13 CA CA000611333A patent/CA1334573C/en not_active Expired - Lifetime
- 1989-09-14 NZ NZ230663A patent/NZ230663A/en unknown
- 1989-09-15 WO PCT/US1989/004002 patent/WO1990002555A1/en active IP Right Grant
- 1989-09-15 ES ES89309381T patent/ES2136055T3/es not_active Expired - Lifetime
- 1989-09-15 DE DE68929031T patent/DE68929031T2/de not_active Expired - Lifetime
- 1989-09-15 MX MX017572A patent/MX168660B/es unknown
- 1989-09-15 AT AT89309381T patent/ATE182081T1/de not_active IP Right Cessation
- 1989-09-15 ZA ZA897060A patent/ZA897060B/xx unknown
- 1989-09-15 AR AR89314940A patent/AR247326A1/es active
- 1989-09-15 JP JP1509897A patent/JPH0649060B2/ja not_active Expired - Lifetime
- 1989-09-15 PH PH39240A patent/PH26017A/en unknown
- 1989-09-15 AU AU43113/89A patent/AU625099B2/en not_active Expired
- 1989-09-15 EP EP89309381A patent/EP0359574B1/en not_active Expired - Lifetime
-
1990
- 1990-05-02 FI FI902194A patent/FI105321B/fi active IP Right Grant
- 1990-05-09 DK DK199001156A patent/DK175224B1/da not_active IP Right Cessation
-
1998
- 1998-12-11 HK HK98113204A patent/HK1011941A1/xx not_active IP Right Cessation
-
1999
- 1999-09-24 GR GR990402430T patent/GR3031328T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH0649060B2 (ja) | 1994-06-29 |
NZ230663A (en) | 1991-05-28 |
EP0359574A3 (en) | 1990-08-29 |
DK115690A (da) | 1990-05-09 |
DE68929031D1 (de) | 1999-08-19 |
PH26017A (en) | 1992-01-29 |
WO1990002555A1 (en) | 1990-03-22 |
DK115690D0 (da) | 1990-05-09 |
ZA897060B (en) | 1991-05-29 |
AU4311389A (en) | 1990-04-02 |
HK1011941A1 (en) | 1999-07-23 |
GR3031328T3 (en) | 1999-12-31 |
FI902194A0 (fi) | 1990-05-02 |
EP0359574A2 (en) | 1990-03-21 |
EP0359574B1 (en) | 1999-07-14 |
US5037647A (en) | 1991-08-06 |
ES2136055T3 (es) | 1999-11-16 |
FI105321B (fi) | 2000-07-31 |
DE68929031T2 (de) | 1999-11-11 |
AU625099B2 (en) | 1992-07-02 |
ATE182081T1 (de) | 1999-07-15 |
JPH02502733A (ja) | 1990-08-30 |
CA1334573C (en) | 1995-02-28 |
MX168660B (es) | 1993-06-02 |
DK175224B1 (da) | 2004-07-12 |
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