AR223454A1 - Nuevos derivados de cis-4a-fenil-2,3,4,4a,5,6,7,7a-octahidro-1h-2-pirindina;procedimiento para obtenerlos y procedimiento para obtener cis-4a-fenil-octahidro-1h-2-pirindina-1-substituida a partir de dichos derivados - Google Patents

Nuevos derivados de cis-4a-fenil-2,3,4,4a,5,6,7,7a-octahidro-1h-2-pirindina;procedimiento para obtenerlos y procedimiento para obtener cis-4a-fenil-octahidro-1h-2-pirindina-1-substituida a partir de dichos derivados

Info

Publication number
AR223454A1
AR223454A1 AR269797A AR26979777A AR223454A1 AR 223454 A1 AR223454 A1 AR 223454A1 AR 269797 A AR269797 A AR 269797A AR 26979777 A AR26979777 A AR 26979777A AR 223454 A1 AR223454 A1 AR 223454A1
Authority
AR
Argentina
Prior art keywords
pirindina
octahidro
fenil
procedure
cis
Prior art date
Application number
AR269797A
Other languages
English (en)
Spanish (es)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of AR223454A1 publication Critical patent/AR223454A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/757Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
AR269797A 1976-11-02 1977-10-31 Nuevos derivados de cis-4a-fenil-2,3,4,4a,5,6,7,7a-octahidro-1h-2-pirindina;procedimiento para obtenerlos y procedimiento para obtener cis-4a-fenil-octahidro-1h-2-pirindina-1-substituida a partir de dichos derivados AR223454A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73795876A 1976-11-02 1976-11-02

Publications (1)

Publication Number Publication Date
AR223454A1 true AR223454A1 (es) 1981-08-31

Family

ID=24965981

Family Applications (1)

Application Number Title Priority Date Filing Date
AR269797A AR223454A1 (es) 1976-11-02 1977-10-31 Nuevos derivados de cis-4a-fenil-2,3,4,4a,5,6,7,7a-octahidro-1h-2-pirindina;procedimiento para obtenerlos y procedimiento para obtener cis-4a-fenil-octahidro-1h-2-pirindina-1-substituida a partir de dichos derivados

Country Status (26)

Country Link
JP (1) JPS5356669A (ru)
AR (1) AR223454A1 (ru)
AT (1) ATA782177A (ru)
AU (1) AU513679B2 (ru)
BE (1) BE860314A (ru)
CA (1) CA1100136A (ru)
CS (1) CS211380B2 (ru)
DD (1) DD133795A5 (ru)
DE (1) DE2748466A1 (ru)
DK (1) DK485277A (ru)
ES (3) ES463784A1 (ru)
FR (1) FR2369267A1 (ru)
GB (1) GB1590155A (ru)
GR (1) GR70053B (ru)
HU (1) HU176231B (ru)
IE (1) IE45901B1 (ru)
IL (1) IL53236A0 (ru)
NL (1) NL7712053A (ru)
NZ (1) NZ185539A (ru)
PH (1) PH12590A (ru)
PL (3) PL108466B1 (ru)
PT (1) PT67194B (ru)
RO (3) RO78300A (ru)
SE (3) SE7712218L (ru)
SU (3) SU812174A3 (ru)
ZA (1) ZA776497B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ189230A (en) * 1977-12-27 1981-05-15 Lilly Co Eli Trans-4a-aryl-2-substituted-octahydro-1h-2-pyrindines
US4236009A (en) * 1979-06-21 1980-11-25 Eli Lilly And Company Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
US4277608A (en) * 1979-06-21 1981-07-07 Eli Lilly And Company Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines
ZA9510829B (en) * 1994-12-23 1996-07-03 Smithkline Beecham Corp 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
HUE028983T2 (en) 2010-05-06 2017-01-30 Vertex Pharma Heterocyclic chromene-spirocyclic piperidine amides as ion channel modulators
ES2573497T3 (es) 2011-02-02 2016-06-08 Vertex Pharmaceuticals Incorporated Pirrolopirazin-amidas de piperidina espirocíclicas como moduladores de canales iónicos
AU2012217616B2 (en) 2011-02-18 2017-03-02 Vertex Pharmaceuticals Incorporated Chroman - spirocyclic piperidine amides as modulators of ion channels
WO2012125613A1 (en) 2011-03-14 2012-09-20 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels

Also Published As

Publication number Publication date
PL108610B1 (en) 1980-04-30
ES463783A1 (es) 1979-07-16
SU913941A3 (en) 1982-03-15
DD133795A5 (de) 1979-01-24
ZA776497B (en) 1979-06-27
ES472276A1 (es) 1979-10-01
RO77935A (ro) 1981-12-25
NL7712053A (nl) 1978-05-05
FR2369267A1 (fr) 1978-05-26
PH12590A (en) 1979-06-27
PL201885A1 (pl) 1978-12-04
PL109690B1 (en) 1980-06-30
GB1590155A (en) 1981-05-28
FR2369267B1 (ru) 1980-05-16
CA1100136A (en) 1981-04-28
ATA782177A (de) 1981-10-15
GR70053B (ru) 1982-07-26
JPS5356669A (en) 1978-05-23
HU176231B (en) 1981-01-28
PT67194A (en) 1977-11-01
SE7712218L (sv) 1978-05-03
RO72900A (ro) 1981-11-04
IE45901B1 (en) 1982-12-29
DE2748466A1 (de) 1978-05-03
ES463784A1 (es) 1978-06-16
DK485277A (da) 1978-05-03
CS211380B2 (en) 1982-02-26
SU845777A3 (ru) 1981-07-07
AU3023577A (en) 1979-05-10
IL53236A0 (en) 1977-12-30
SU812174A3 (ru) 1981-03-07
PL108466B1 (en) 1980-04-30
SE8103107L (sv) 1981-05-18
PT67194B (en) 1979-03-23
NZ185539A (en) 1979-12-11
AU513679B2 (en) 1980-12-18
BE860314A (fr) 1978-04-28
IE45901L (en) 1978-05-02
RO78300A (ro) 1982-04-12
SE8103106L (sv) 1981-05-18

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