AR223454A1 - NEW DERIVATIVES OF CIS-4A-FENIL-2,3,4,4A, 5,6,7,7A-OCTAHIDRO-1H-2-PIRINDINA; PROCEDURE TO OBTAIN THEM AND PROCEDURE TO OBTAIN CIS-4A-FENIL-OCTAHIDRO-1H- 2-PIRINDINA-1-SUBSTITUTED FROM THESE DERIVATIVES - Google Patents

NEW DERIVATIVES OF CIS-4A-FENIL-2,3,4,4A, 5,6,7,7A-OCTAHIDRO-1H-2-PIRINDINA; PROCEDURE TO OBTAIN THEM AND PROCEDURE TO OBTAIN CIS-4A-FENIL-OCTAHIDRO-1H- 2-PIRINDINA-1-SUBSTITUTED FROM THESE DERIVATIVES

Info

Publication number
AR223454A1
AR223454A1 AR269797A AR26979777A AR223454A1 AR 223454 A1 AR223454 A1 AR 223454A1 AR 269797 A AR269797 A AR 269797A AR 26979777 A AR26979777 A AR 26979777A AR 223454 A1 AR223454 A1 AR 223454A1
Authority
AR
Argentina
Prior art keywords
pirindina
octahidro
fenil
procedure
cis
Prior art date
Application number
AR269797A
Other languages
Spanish (es)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of AR223454A1 publication Critical patent/AR223454A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/757—Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
AR269797A 1976-11-02 1977-10-31 NEW DERIVATIVES OF CIS-4A-FENIL-2,3,4,4A, 5,6,7,7A-OCTAHIDRO-1H-2-PIRINDINA; PROCEDURE TO OBTAIN THEM AND PROCEDURE TO OBTAIN CIS-4A-FENIL-OCTAHIDRO-1H- 2-PIRINDINA-1-SUBSTITUTED FROM THESE DERIVATIVES AR223454A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73795876A 1976-11-02 1976-11-02

Publications (1)

Publication Number Publication Date
AR223454A1 true AR223454A1 (en) 1981-08-31

Family

ID=24965981

Family Applications (1)

Application Number Title Priority Date Filing Date
AR269797A AR223454A1 (en) 1976-11-02 1977-10-31 NEW DERIVATIVES OF CIS-4A-FENIL-2,3,4,4A, 5,6,7,7A-OCTAHIDRO-1H-2-PIRINDINA; PROCEDURE TO OBTAIN THEM AND PROCEDURE TO OBTAIN CIS-4A-FENIL-OCTAHIDRO-1H- 2-PIRINDINA-1-SUBSTITUTED FROM THESE DERIVATIVES

Country Status (26)

Country Link
JP (1) JPS5356669A (en)
AR (1) AR223454A1 (en)
AT (1) ATA782177A (en)
AU (1) AU513679B2 (en)
BE (1) BE860314A (en)
CA (1) CA1100136A (en)
CS (1) CS211380B2 (en)
DD (1) DD133795A5 (en)
DE (1) DE2748466A1 (en)
DK (1) DK485277A (en)
ES (3) ES463783A1 (en)
FR (1) FR2369267A1 (en)
GB (1) GB1590155A (en)
GR (1) GR70053B (en)
HU (1) HU176231B (en)
IE (1) IE45901B1 (en)
IL (1) IL53236A0 (en)
NL (1) NL7712053A (en)
NZ (1) NZ185539A (en)
PH (1) PH12590A (en)
PL (3) PL108610B1 (en)
PT (1) PT67194B (en)
RO (3) RO78300A (en)
SE (3) SE7712218L (en)
SU (3) SU812174A3 (en)
ZA (1) ZA776497B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL117572B1 (en) * 1977-12-27 1981-08-31 Lilly Co Eli Process for preparing novel derivatives of trans-4a-phenyl-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindine3,4,4a,5,6,7,7a-oktagidro-1h-2-piridina
US4236009A (en) * 1979-06-21 1980-11-25 Eli Lilly And Company Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
US4277608A (en) * 1979-06-21 1981-07-07 Eli Lilly And Company Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines
ZA9510829B (en) * 1994-12-23 1996-07-03 Smithkline Beecham Corp 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
CA2812526A1 (en) 2010-05-06 2011-11-10 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
AU2012212196B2 (en) 2011-02-02 2016-10-13 Vertex Pharmaceuticals Incorporated Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels
CA2827311A1 (en) 2011-02-18 2012-08-23 Vertex Pharmaceuticals Incorporated Chroman-spirocyclic piperidine amides as modulators of ion channels
CA2829803A1 (en) 2011-03-14 2012-09-20 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels

Also Published As

Publication number Publication date
HU176231B (en) 1981-01-28
GR70053B (en) 1982-07-26
IL53236A0 (en) 1977-12-30
SE8103107L (en) 1981-05-18
NZ185539A (en) 1979-12-11
SE7712218L (en) 1978-05-02
SE8103106L (en) 1981-05-18
DD133795A5 (en) 1979-01-24
DE2748466A1 (en) 1978-05-03
ZA776497B (en) 1979-06-27
FR2369267B1 (en) 1980-05-16
BE860314A (en) 1978-04-28
ES472276A1 (en) 1979-10-01
PT67194A (en) 1977-11-01
PT67194B (en) 1979-03-23
SU812174A3 (en) 1981-03-07
CA1100136A (en) 1981-04-28
ES463783A1 (en) 1979-07-16
RO77935A (en) 1981-12-25
DK485277A (en) 1978-05-03
PL108610B1 (en) 1980-04-30
GB1590155A (en) 1981-05-28
SU913941A3 (en) 1982-03-15
SU845777A3 (en) 1981-07-07
PL201885A1 (en) 1978-12-04
CS211380B2 (en) 1982-02-26
RO78300A (en) 1982-04-12
IE45901L (en) 1978-05-02
PL108466B1 (en) 1980-04-30
AU513679B2 (en) 1980-12-18
IE45901B1 (en) 1982-12-29
JPS5356669A (en) 1978-05-23
PL109690B1 (en) 1980-06-30
NL7712053A (en) 1978-05-05
PH12590A (en) 1979-06-27
AU3023577A (en) 1979-05-10
ATA782177A (en) 1981-10-15
RO72900A (en) 1981-11-04
FR2369267A1 (en) 1978-05-26
ES463784A1 (en) 1978-06-16

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