PL201885A1 - Sposob wytwarzania 4a-arylo-osmiowodoro-1h-2-piryndyn - Google Patents

Sposob wytwarzania 4a-arylo-osmiowodoro-1h-2-piryndyn

Info

Publication number
PL201885A1
PL201885A1 PL20188577A PL20188577A PL201885A1 PL 201885 A1 PL201885 A1 PL 201885A1 PL 20188577 A PL20188577 A PL 20188577A PL 20188577 A PL20188577 A PL 20188577A PL 201885 A1 PL201885 A1 PL 201885A1
Authority
PL
Poland
Prior art keywords
octiahydrogen
pyrindine
aryl
manufacturing
Prior art date
Application number
PL20188577A
Other languages
English (en)
Other versions
PL109690B1 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL201885A1 publication Critical patent/PL201885A1/pl
Publication of PL109690B1 publication Critical patent/PL109690B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/757Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PL1977201885A 1976-11-02 1977-11-02 Method of producing cis-4a-phenylo-2-substituted-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindines PL109690B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73795876A 1976-11-02 1976-11-02

Publications (2)

Publication Number Publication Date
PL201885A1 true PL201885A1 (pl) 1978-12-04
PL109690B1 PL109690B1 (en) 1980-06-30

Family

ID=24965981

Family Applications (3)

Application Number Title Priority Date Filing Date
PL1977201885A PL109690B1 (en) 1976-11-02 1977-11-02 Method of producing cis-4a-phenylo-2-substituted-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindines
PL1977212226A PL108466B1 (en) 1976-11-02 1977-11-02 Method of producing cis 4a-arylooctahydro-1h-2-pyrindins
PL1977212225A PL108610B1 (en) 1976-11-02 1977-11-02 Method of producing cis-4a-phenylo-2-substituted-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindines

Family Applications After (2)

Application Number Title Priority Date Filing Date
PL1977212226A PL108466B1 (en) 1976-11-02 1977-11-02 Method of producing cis 4a-arylooctahydro-1h-2-pyrindins
PL1977212225A PL108610B1 (en) 1976-11-02 1977-11-02 Method of producing cis-4a-phenylo-2-substituted-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindines

Country Status (26)

Country Link
JP (1) JPS5356669A (pl)
AR (1) AR223454A1 (pl)
AT (1) ATA782177A (pl)
AU (1) AU513679B2 (pl)
BE (1) BE860314A (pl)
CA (1) CA1100136A (pl)
CS (1) CS211380B2 (pl)
DD (1) DD133795A5 (pl)
DE (1) DE2748466A1 (pl)
DK (1) DK485277A (pl)
ES (3) ES463784A1 (pl)
FR (1) FR2369267A1 (pl)
GB (1) GB1590155A (pl)
GR (1) GR70053B (pl)
HU (1) HU176231B (pl)
IE (1) IE45901B1 (pl)
IL (1) IL53236A0 (pl)
NL (1) NL7712053A (pl)
NZ (1) NZ185539A (pl)
PH (1) PH12590A (pl)
PL (3) PL109690B1 (pl)
PT (1) PT67194B (pl)
RO (3) RO78300A (pl)
SE (3) SE7712218L (pl)
SU (3) SU812174A3 (pl)
ZA (1) ZA776497B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL117572B1 (en) * 1977-12-27 1981-08-31 Lilly Co Eli Process for preparing novel derivatives of trans-4a-phenyl-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindine3,4,4a,5,6,7,7a-oktagidro-1h-2-piridina
US4236009A (en) * 1979-06-21 1980-11-25 Eli Lilly And Company Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
US4277608A (en) * 1979-06-21 1981-07-07 Eli Lilly And Company Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines
ZA9510829B (en) * 1994-12-23 1996-07-03 Smithkline Beecham Corp 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
WO2011140425A1 (en) 2010-05-06 2011-11-10 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
TW201604196A (zh) 2011-02-02 2016-02-01 維泰克斯製藥公司 作為離子通道調節劑之吡咯并吡-螺環哌啶醯胺
MX2013009393A (es) 2011-02-18 2013-08-29 Vertex Pharma Piperidinamidas cromano-espirociclicas como moduladores de canales de iones.
EP2686325B1 (en) 2011-03-14 2016-12-14 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels

Also Published As

Publication number Publication date
SU812174A3 (ru) 1981-03-07
GB1590155A (en) 1981-05-28
ZA776497B (en) 1979-06-27
HU176231B (en) 1981-01-28
PL108610B1 (en) 1980-04-30
DE2748466A1 (de) 1978-05-03
RO72900A (ro) 1981-11-04
ATA782177A (de) 1981-10-15
ES463783A1 (es) 1979-07-16
DK485277A (da) 1978-05-03
BE860314A (fr) 1978-04-28
PT67194B (en) 1979-03-23
SU913941A3 (en) 1982-03-15
AU513679B2 (en) 1980-12-18
GR70053B (pl) 1982-07-26
SE7712218L (sv) 1978-05-03
IL53236A0 (en) 1977-12-30
FR2369267A1 (fr) 1978-05-26
NZ185539A (en) 1979-12-11
ES463784A1 (es) 1978-06-16
SE8103107L (sv) 1981-05-18
ES472276A1 (es) 1979-10-01
SU845777A3 (ru) 1981-07-07
IE45901L (en) 1978-05-02
CS211380B2 (en) 1982-02-26
PL109690B1 (en) 1980-06-30
FR2369267B1 (pl) 1980-05-16
RO77935A (ro) 1981-12-25
AU3023577A (en) 1979-05-10
SE8103106L (sv) 1981-05-18
JPS5356669A (en) 1978-05-23
PT67194A (en) 1977-11-01
CA1100136A (en) 1981-04-28
PL108466B1 (en) 1980-04-30
IE45901B1 (en) 1982-12-29
AR223454A1 (es) 1981-08-31
PH12590A (en) 1979-06-27
DD133795A5 (de) 1979-01-24
RO78300A (ro) 1982-04-12
NL7712053A (nl) 1978-05-05

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