AR075927A1 - Procedimiento para la produccion de glioxilato mediante fermentacion - Google Patents

Procedimiento para la produccion de glioxilato mediante fermentacion

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Publication number
AR075927A1
AR075927A1 ARP100100930A ARP100100930A AR075927A1 AR 075927 A1 AR075927 A1 AR 075927A1 AR P100100930 A ARP100100930 A AR P100100930A AR P100100930 A ARP100100930 A AR P100100930A AR 075927 A1 AR075927 A1 AR 075927A1
Authority
AR
Argentina
Prior art keywords
procedure
production
glioxylate
fermentation
recombinant microorganism
Prior art date
Application number
ARP100100930A
Other languages
English (en)
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of AR075927A1 publication Critical patent/AR075927A1/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Procedimiento para la bioconversion de una fuente de carbono fermentable en glioxilato mediante un microorganismo recombinante con modificaciones genéticas como por ejemplo deltaldhA, deltamgsA, deltaarcA y deltalldP, deltaglcA, deltayjcG y la combinacion de ellas que permite una produccion con mayor rendimiento, valoracion y productividad. Se provee además el microorganismo recombinante que pertenece al género Escherichia.
ARP100100930A 2009-03-24 2010-03-23 Procedimiento para la produccion de glioxilato mediante fermentacion AR075927A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16271209P 2009-03-24 2009-03-24
EP09155971A EP2233562A1 (en) 2009-03-24 2009-03-24 Method for producing high amount of glycolic acid by fermentation

Publications (1)

Publication Number Publication Date
AR075927A1 true AR075927A1 (es) 2011-05-04

Family

ID=40671604

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100100930A AR075927A1 (es) 2009-03-24 2010-03-23 Procedimiento para la produccion de glioxilato mediante fermentacion

Country Status (12)

Country Link
US (1) US8945888B2 (es)
EP (2) EP2233562A1 (es)
JP (1) JP5800795B2 (es)
KR (1) KR101764933B1 (es)
CN (1) CN102365357A (es)
AR (1) AR075927A1 (es)
BR (1) BRPI1012693B1 (es)
CA (1) CA2754949C (es)
ES (1) ES2593084T3 (es)
MX (1) MX2011010024A (es)
MY (1) MY164623A (es)
WO (1) WO2010108909A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2480679A2 (en) * 2009-09-25 2012-08-01 Roquette Frères Fermentation process for producing glycolic acid
WO2011083059A1 (en) * 2010-01-06 2011-07-14 Universiteit Gent Bacterial mutants and uses thereof in protein production
CN103221548B (zh) 2010-06-15 2017-04-12 代谢探索者公司 诱导型启动子在乙醇酸的产生中的用途
JP2013537429A (ja) * 2010-08-27 2013-10-03 メタボリック エクスプローラー 改変微生物による改良されたグリコール酸発酵生産
FI125136B (en) 2011-10-04 2015-06-15 Teknologian Tutkimuskeskus Vtt Oy Eukaryotic cells and a method for preparing glycolic acid
EP2791367B1 (en) 2011-12-16 2019-04-24 Inbiose N.V. Mutant microorganisms to synthesize colanic acid, mannosylated and/or fucosylated oligosaccharides
WO2014158594A1 (en) * 2013-03-14 2014-10-02 President And Fellows Of Harvard College Methods for selecting microbes from a genetically modified library to detect and optimize the production of metabolites
JP2016163540A (ja) * 2013-07-09 2016-09-08 味の素株式会社 有用物質の製造方法
FR3028529B1 (fr) 2014-11-19 2016-12-30 Inst Nat De La Rech Agronomique Inra Procede de production d'au moins un metabolite d'interet par transformation d'un pentose dans un microorganisme
FI20155412A (fi) * 2015-05-29 2016-11-30 Teknologian Tutkimuskeskus Vtt Oy Sokerien suora konversio glykolihapoksi
US10294481B2 (en) 2015-10-02 2019-05-21 Massachusetts Institute Of Technology Microbial production of renewable glycolate
CN106011185B (zh) * 2016-06-27 2019-12-17 江南大学 一种无基因敲除提高大肠杆菌中乙醇酸产率的方法
RU2760290C1 (ru) 2016-07-08 2021-11-23 Метаболик Эксплорер Способ ферментативной продукции целевых молекул микроорганизмами, включающими гены, кодирующие фосфотрансферазную систему (фтс) сахаров
EP3354742A1 (en) 2017-01-26 2018-08-01 Metabolic Explorer Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid
EP3679152A4 (en) 2017-09-07 2021-06-09 The Governing Council of the University of Toronto PRODUCTION OF GLYCOLATE FROM ETHYLENE GLYCOL AND RELATED MICROBIAL ENGINEERING
WO2019068642A1 (en) 2017-10-02 2019-04-11 Metabolic Explorer PROCESS FOR PRODUCING ORGANIC ACID SALTS FROM A FERMENTATION BROTH
EP3914737A1 (en) 2019-01-24 2021-12-01 Photanol B.V. A process for the bioproduction of glycolate
EP3906313A1 (en) 2019-02-15 2021-11-10 Braskem S.A. Microorganisms and methods for the production of glycolic acid and glycine via reverse glyoxylate shunt
EP3908663A1 (en) 2019-02-20 2021-11-17 Braskem S.A. Microorganisms and methods for the production of oxygenated compounds from hexoses
JP7463388B2 (ja) * 2019-02-20 2024-04-08 ブラスケム エス.エー. ペントース糖およびヘキソース糖のための分解経路
CN113025506B (zh) * 2019-12-24 2022-12-09 中国科学院天津工业生物技术研究所 一种生产乙醇的重组丝状真菌及其构建和应用
KR102558672B1 (ko) * 2022-05-17 2023-07-25 주식회사 엑티브온 1,3-프로판디올 생산 변이 미생물 및 이를 이용한 1,3-프로판디올의 생산 방법
WO2024084032A1 (de) 2022-10-20 2024-04-25 Annikki Gmbh Verfahren zur herstellung einer wässerigen lösung enthaltend ein alkalisalz der glycolsäure und der milchsäure

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2374482C (en) 1999-05-21 2012-09-18 Cargill Dow Llc Methods and materials for the synthesis of organic products
AU2003205041A1 (en) 2002-07-12 2004-01-29 Ajinomoto Co., Inc. Method for producing target substance by fermentation
KR101148255B1 (ko) 2002-10-04 2012-08-08 다니스코 유에스 인크. 고수율을 갖는 1,3-프로판디올의 생물학적 제조 방법
US7262046B2 (en) 2004-08-09 2007-08-28 Rice University Aerobic succinate production in bacteria
WO2006034156A2 (en) * 2004-09-17 2006-03-30 Rice University High succinate producing bacteria
US20070116852A1 (en) 2005-11-22 2007-05-24 Josef Schnatmann Cattle feed preparation
WO2007140816A1 (en) * 2006-06-09 2007-12-13 Metabolic Explorer Glycolic acid production by fermentation from renewable resources
KR100780324B1 (ko) 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
BRPI0809039A2 (pt) 2007-03-23 2014-09-16 Metabolic Explorer Sa Microorganismos metabolicamente projetados úteis para a produção de 1,2-propanodiol
KR101528943B1 (ko) 2007-03-23 2015-06-15 메타볼릭 익스플로러 진화 및 합리적 설계의 조합에 의해 수득된 1,2―프로판디올의 생산을 위한 신규한 미생물

Also Published As

Publication number Publication date
CA2754949A1 (en) 2010-09-30
KR101764933B1 (ko) 2017-08-03
BRPI1012693A2 (pt) 2015-09-15
EP2411502B1 (en) 2016-08-03
MX2011010024A (es) 2011-10-10
JP5800795B2 (ja) 2015-10-28
CA2754949C (en) 2021-07-06
US8945888B2 (en) 2015-02-03
BRPI1012693B1 (pt) 2019-11-12
US20120315682A1 (en) 2012-12-13
EP2233562A1 (en) 2010-09-29
WO2010108909A1 (en) 2010-09-30
CN102365357A (zh) 2012-02-29
JP2012521206A (ja) 2012-09-13
EP2411502A1 (en) 2012-02-01
MY164623A (en) 2018-01-30
ES2593084T3 (es) 2016-12-05
KR20120002593A (ko) 2012-01-06

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