AR068702A1 - Composiciones farmaceuticas - Google Patents
Composiciones farmaceuticasInfo
- Publication number
- AR068702A1 AR068702A1 ARP080103498A ARP080103498A AR068702A1 AR 068702 A1 AR068702 A1 AR 068702A1 AR P080103498 A ARP080103498 A AR P080103498A AR P080103498 A ARP080103498 A AR P080103498A AR 068702 A1 AR068702 A1 AR 068702A1
- Authority
- AR
- Argentina
- Prior art keywords
- postmenopausal women
- dehydroepiandrosterone
- steroid precursor
- comprises administering
- circulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Pregnancy & Childbirth (AREA)
- Neurology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
Reivindicacion 1: Un método para tratar y/o reducir la probabilidad de adquirir los síntomas o enfermedades debidos a la menopausia, en mujeres postmenopáusicas, caracterizado porque dicho método comprende administrar un precursor de esteroides sexuales seleccionado del grupo formado por dehidroepiandrosterona, sulfato de dehidroepiandrosterona, androst-5-en-3beta,17beta-diol y 4-androsten-3,17-diona a un paciente que necesita de dicho tratamiento, en donde dicho precursor de esteroides sexuales es administrada como una cantidad terapéutica que incrementa el nivel de metabolitos de androgeno en la circulacion sin incrementar el nivel en circulacion de estradiol por encima de los valores observados en mujeres postmenopáusicas normales con el fin de evitar el riesgo de cáncer de mama y utero. Reivindicacion 23: Un método para tratar y/o reducir la probabilidad de adquirir síntomas o enfermedades debidas a la menopausia, en mujeres postmenopáusicas, caracterizado porque dicho método comprende administrar un precursor de esteroides sexuales seleccionado del grupo formado por dehidroepiandrosterona, sulfato de dehidroepiandrosterona, androst-5-en-3beta,17beta-diol y 4-androsten-3,17-diona a un paciente que necesita de dicho tratamiento, en donde dicho precursor de esteroides sexuales es administrado como una cantidad terapéutica que incrementa el nivel de metabolitos de androgeno en la circulacion y además comprende administrar como parte de una terapia combinada, una cantidad eficaz para uso terapéutico de un modulador selectivo del receptor de estrogeno con el fin de disminuir el riesgo de cáncer de mama y utero que normalmente se observan en mujeres postmenopáusicas y para prevenir la pérdida osea, la acumulacion de grasas y la diabetes tipo 2. Reivindicacion 24: El método de las reivindicaciones 21 y 22, caracterizado porque el modulador selectivo del receptor de estrogeno presenta la estructura química de formula (1).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96427007P | 2007-08-10 | 2007-08-10 | |
US96467307P | 2007-08-13 | 2007-08-13 | |
US12/221,847 US8268806B2 (en) | 2007-08-10 | 2008-08-07 | Pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
AR068702A1 true AR068702A1 (es) | 2009-12-02 |
Family
ID=40350317
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080103498A AR068702A1 (es) | 2007-08-10 | 2008-08-11 | Composiciones farmaceuticas |
ARP180103856A AR114051A2 (es) | 2007-08-10 | 2018-12-26 | Composiciones farmacéuticas y supositorio vaginal |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP180103856A AR114051A2 (es) | 2007-08-10 | 2018-12-26 | Composiciones farmacéuticas y supositorio vaginal |
Country Status (28)
Country | Link |
---|---|
US (5) | US8268806B2 (es) |
EP (2) | EP2441456B1 (es) |
JP (2) | JP5725283B2 (es) |
KR (3) | KR101638130B1 (es) |
CN (4) | CN105412121A (es) |
AR (2) | AR068702A1 (es) |
AU (1) | AU2008286651B2 (es) |
BR (1) | BRPI0815353A2 (es) |
CA (2) | CA2820566C (es) |
CO (1) | CO6260084A2 (es) |
DK (1) | DK2185157T3 (es) |
EA (2) | EA201200369A1 (es) |
EC (1) | ECSP10010016A (es) |
ES (1) | ES2888104T3 (es) |
HK (1) | HK1217639A1 (es) |
IL (1) | IL203747A (es) |
MA (1) | MA31694B1 (es) |
MX (1) | MX2010001627A (es) |
NO (1) | NO20100300L (es) |
NZ (2) | NZ583147A (es) |
PE (2) | PE20090945A1 (es) |
PH (1) | PH12013502291B1 (es) |
PT (1) | PT2185157T (es) |
SA (2) | SA08290494B1 (es) |
SG (3) | SG183702A1 (es) |
TN (1) | TN2010000065A1 (es) |
TW (3) | TWI565468B (es) |
WO (1) | WO2009021323A1 (es) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997012623A1 (en) * | 1995-10-06 | 1997-04-10 | Arch Development Corporation | Methods and compositions for viral enhancement of cell killing |
US6465445B1 (en) * | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
BRPI0516243C1 (pt) | 2004-10-20 | 2021-05-25 | Endorecherche Inc | uso de um precursor de esteróide sexual selecionado do grupo que consiste em dehidroepiandrosterona, sulfato de dehidroepiandrosterona, androst-5-eno-3b,17b-diol e 4-androsten-3,17-diona, uso do referido precursor em 5 associação com um modulador de receptor de estrogênio seletivo para proteção uterina e da glândula mamária contra câncer, composição farmacêutica e kit |
CA2654152A1 (en) | 2006-06-02 | 2007-12-13 | Pear Tree Women's Health Care | Method of treating atrophic vaginitis |
US9284345B2 (en) * | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
WO2010118384A2 (en) * | 2009-04-10 | 2010-10-14 | Amylin Pharmaceuticals, Inc. | Amylin agonist compounds for estrogen-deficient mammals |
US20100317635A1 (en) * | 2009-06-16 | 2010-12-16 | Endorecherche, Inc. | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
JP6285866B2 (ja) | 2011-11-23 | 2018-02-28 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然複合ホルモン補充製剤および療法 |
BR112014014308A2 (pt) * | 2011-12-29 | 2017-06-13 | Laboratorios Andrómaco S A | anel vaginal que inclui dhea ou sulfato de dhea e, opcionalmente, um agente para modular a liberação do princípio ativo, que pode ser usado para aumentar a reserva ovariana nas mulheres e para aliviar os sintomas associados à menopausa |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20140045806A1 (en) * | 2012-07-25 | 2014-02-13 | Fernand Labrie | Sexual arousal, sexual desire, orgasm and/or pleasure following intravaginal prasterone (dhea) administration in women not suffering or independently from dyspareunia or other symptoms of vulvo-vaginal atrophy |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
US9744177B2 (en) | 2014-03-10 | 2017-08-29 | Endorecherche, Inc. | Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM |
AU2015264003A1 (en) | 2014-05-22 | 2016-11-17 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
MX2016013693A (es) | 2014-07-29 | 2017-10-31 | Therapeuticsmd Inc | Crema transdermica. |
RU2019117364A (ru) * | 2014-10-16 | 2019-08-05 | ДжиТиИкс, ИНК. | Способы лечения урологических нарушений с применением селективных модуляторов андрогеновых рецепторов |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US9862101B2 (en) | 2015-12-22 | 2018-01-09 | Varian Semiconductor Equipment Associats, Inc. | Self-damping end effector |
RU2618428C1 (ru) * | 2016-03-24 | 2017-05-03 | Общество с ограниченной ответственностью "Научно-производственное предприятие Лаборатория Матрикс" | Комплексное косметическое средство |
EP3435977A4 (en) | 2016-04-01 | 2019-10-16 | Therapeuticsmd, Inc. | PHARMACEUTICAL COMPOSITION OF STEROID HORMONE |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
US10285998B1 (en) | 2018-04-04 | 2019-05-14 | The Menopause Method, Inc. | Composition and method to aid in hormone replacement therapy |
CN109364171A (zh) * | 2018-05-25 | 2019-02-22 | 泓博元生命科技(深圳)有限公司 | 含有nadh和dhea的卵巢保养组合物、制剂及其制备方法 |
CN109350624A (zh) * | 2018-05-25 | 2019-02-19 | 泓博元生命科技(深圳)有限公司 | 含有nmn和dhea的女性保健组合物、制剂及其制备方法与应用 |
CN114126551A (zh) * | 2019-03-29 | 2022-03-01 | B·马特尔 | 分段式eva阴道内环 |
JP6945874B2 (ja) * | 2019-12-24 | 2021-10-06 | 一般財団法人バイオダイナミックス研究所 | 経口投与用医薬組成物 |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
WO2024068968A1 (en) * | 2022-09-29 | 2024-04-04 | Rigshospitalet | Inhibition of luteinizing hormone (lh) action as treatment of perimenopausal and postmenopausal symptoms and complications |
Family Cites Families (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63104924A (ja) * | 1986-10-20 | 1988-05-10 | Kanebo Ltd | 膣坐剤 |
US4835147A (en) | 1987-05-06 | 1989-05-30 | City Of Hope | Dehydroepiandrosterone therapy for ameleoration of prostate hypertrophy and sexual dysfunction |
US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
US5407684A (en) * | 1988-12-30 | 1995-04-18 | Virginia Commonwealth University | Use of DHEA as a medicinal |
US5246704A (en) * | 1989-01-23 | 1993-09-21 | Kanebo, Ltd. | Vaginal suppository |
WO1990010462A1 (en) | 1989-03-10 | 1990-09-20 | Endorecherche Inc. | Combination therapy for treatment of estrogen sensitive diseases |
CA2062792C (en) | 1989-07-07 | 2006-03-21 | Fernard Labrie | Treatment of androgen-related diseases |
EP0943328B1 (en) | 1989-07-07 | 2004-06-16 | Endorecherche Inc. | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia |
HU222501B1 (hu) * | 1991-06-28 | 2003-07-28 | Endorecherche Inc. | MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására |
US6060503A (en) | 1991-12-02 | 2000-05-09 | Endorecherche, Inc. | Benzopyran-containing compounds and method for their use |
CN1100541C (zh) * | 1993-01-19 | 2003-02-05 | 恩多研究公司 | 脱氢表雄酮的治疗用途和传送系统 |
US5776923A (en) | 1993-01-19 | 1998-07-07 | Endorecherche, Inc. | Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone |
JP2698865B2 (ja) * | 1994-08-08 | 1998-01-19 | 仲昭 大澤 | 筋緊張性ジストロフィー症治療剤 |
US5660835A (en) * | 1995-02-24 | 1997-08-26 | East Carolina University | Method of treating adenosine depletion |
US20020032160A1 (en) * | 1995-02-24 | 2002-03-14 | Nyce Jonathan W. | Compositions & formulations with an epiandrosterone or a ubiquinone & kits & their use for treatment of asthma symptoms & for reducing adenosine/adenosine receptor levels |
US5726202A (en) | 1996-01-11 | 1998-03-10 | Novo Nordisk A/S | Benign prostatic hypertrophy |
CA2241462A1 (en) | 1996-01-11 | 1997-07-17 | Novo Nordisk A/S | Use of the l-enantiomer of centchroman for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of breast cancer |
BR9706967A (pt) | 1996-01-11 | 1999-05-04 | Novo Nordisk As | Utilização de compostos e processo para tratamento e profilaxia de sintomas relacionados à menopausa |
US5747059A (en) | 1996-01-11 | 1998-05-05 | Novo Nordisk A/S | Atrophy of skin/mucous membrane |
US5883118A (en) | 1996-01-11 | 1999-03-16 | Nova Nordisk A/S | Prostatic carcinoma |
EP0802183B1 (en) | 1996-04-19 | 2001-10-10 | American Home Products Corporation | Estrogenic agents |
TW397821B (en) | 1996-04-19 | 2000-07-11 | American Home Produits Corp | 3-[4-(2-phenyl-indole-1-ylmethyl)-phenyl]-acrylamides and 2-phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol as well as pharmaceutical compositions of estrogenic agents thereof |
US20020013304A1 (en) * | 1997-10-28 | 2002-01-31 | Wilson Leland F. | As-needed administration of an androgenic agent to enhance female sexual desire and responsiveness |
US20040044080A1 (en) * | 1997-10-28 | 2004-03-04 | Place Virgil A. | Treatment of dyspareunia with topically administered nitroglycerin formulations |
US20020099003A1 (en) * | 1997-10-28 | 2002-07-25 | Wilson Leland F. | Treatment of female sexual dysfunction with vasoactive agents, particularly vasoactive intestinal polypeptide and agonists thereof |
US20040014761A1 (en) * | 1997-10-28 | 2004-01-22 | Place Virgil A. | Treatment of female sexual dysfunction with phosphodiesterase inhibitors |
AU740758B2 (en) * | 1997-10-28 | 2001-11-15 | Vivus, Inc. | Treatment of female sexual dysfunction |
US20050070516A1 (en) * | 1997-10-28 | 2005-03-31 | Vivus Inc. | As-needed administration of an androgenic agent to enhance female desire and responsiveness |
US6013665A (en) * | 1997-12-16 | 2000-01-11 | Abbott Laboratories | Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides |
US7005428B1 (en) * | 1998-06-11 | 2006-02-28 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
US6465445B1 (en) * | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
CN100377711C (zh) | 1998-06-11 | 2008-04-02 | 内部研究股份有限公司 | 雄-5-烯-3β,17β-二醇的药物组合物及其用途 |
US6007824A (en) * | 1998-07-09 | 1999-12-28 | Duckett; Melvin J. | Natural composition and method for the treatment of sexual dysfunction |
US20030181353A1 (en) * | 1998-08-03 | 2003-09-25 | Nyce Jonathan W. | Composition & use as analgesic, anti-inflammatory, wound healing agent, for treatment of heart conditions, assessment of heart function & tissue & cell protection & healing & reperfusion, mood disorders & symptoms & sequelae of menopause & for inducing unconsciousness, sleep & anesthesia |
IT1304190B1 (it) * | 1998-12-18 | 2001-03-08 | Euphar Group Srl | Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6087362A (en) * | 1999-03-16 | 2000-07-11 | Pentech Pharmaceuticals, Inc. | Apomorphine and sildenafil composition |
US7045513B1 (en) * | 1999-03-18 | 2006-05-16 | Genelabs Technologies, Inc. | DHEA composition and method |
TR200200406T2 (tr) * | 1999-06-11 | 2002-06-21 | Watson Pharmaceuticals, Inc. | Kadınlara oral olmayan yollarla androjenik steroidlerin uygulanması |
US7452545B2 (en) * | 2001-11-13 | 2008-11-18 | Yu Ruey J | Oligosaccharide aldonic acids and their topical use |
US6335023B1 (en) * | 1999-06-30 | 2002-01-01 | Ruey J. Yu | Oligosaccharide aldonic acids and their topical use |
US20050245494A1 (en) * | 1999-07-01 | 2005-11-03 | 40 J's Llc | Methods to treat one or all of the defined etiologies of female sexual dysfunction |
US20020165429A1 (en) * | 1999-07-01 | 2002-11-07 | 40 J's Llc | Clitoral sensitizing arrangements |
US20070042060A1 (en) * | 1999-07-01 | 2007-02-22 | Thompson Ronald J | Methods to treat one or all of the defined etiologies of female sexual Dysfunction |
TWI359015B (en) | 1999-07-06 | 2012-03-01 | Endorech Inc | Pharmaceutical composition for treatment or preve |
RU2342145C2 (ru) | 2000-01-28 | 2008-12-27 | Андорешерш, Инк. | Селективные модуляторы рецептора эстрогена в комбинации с эстрогенами |
US20020022052A1 (en) * | 2000-04-06 | 2002-02-21 | Dransfield Charles William | Transdermal delivery system |
US20040198706A1 (en) | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
IL145838A (en) * | 2000-10-16 | 2008-11-03 | Pfizer Prod Inc | Use of an estrogen agonist / antagonist to produce a drug for the treatment of vaginitis |
US20020107230A1 (en) * | 2000-12-22 | 2002-08-08 | Waldon R. Forrest | Methods and formulations for the treatment of female sexual dysfunction |
EP1351678A2 (en) * | 2001-01-02 | 2003-10-15 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
AU2002303427A1 (en) * | 2001-04-24 | 2002-11-05 | East Carolina University | Compositions and formulations with a non-glucocorticoid steroid and/or a ubiquinone and kit for treatment of respiratory and lung disease |
WO2002085296A2 (en) * | 2001-04-24 | 2002-10-31 | Epigenesis Pharmaceuticals, Inc. | Composition, formulations and kit for treatment of respiratory and lung disease with non-glucocorticoid steroids and/or ubiquinone and a bronchodilating agent |
US20030216329A1 (en) * | 2001-04-24 | 2003-11-20 | Robinson Cynthia B. | Composition, formulations & kit for treatment of respiratory & lung disease with dehydroepiandrosterone(s) steroid & an anti-muscarinic agent(s) |
AU2002256359A1 (en) | 2001-04-24 | 2002-11-05 | Epigenesis Pharmaceuticals, Inc. | Antisense and anti-inflammatory based compositions to treat respiratory disorders |
US20030004145A1 (en) | 2001-05-16 | 2003-01-02 | Leonard Thomas W. | Treatment of conditions relating to hormone deficiencies by administration of progestins |
US20030022875A1 (en) | 2001-07-27 | 2003-01-30 | Wilson Leland F. | As-needed administration of orally active androgenic agents to enhance female sexual desire and responsiveness |
FR2828100B1 (fr) * | 2001-08-02 | 2004-09-24 | Galderma Res & Dev | Composition de type emulsion inverse contenant de la dhea et/ou ses precurseurs ou derives, et ses utilisations en cosmetique et en dermatologie |
US20030138434A1 (en) * | 2001-08-13 | 2003-07-24 | Campbell Robert L. | Agents for enhancing the immune response |
US7348352B2 (en) * | 2001-10-23 | 2008-03-25 | Bioresponse L.L.C. | Diindolylmethane for the treatment of HPV infection |
WO2003037334A1 (en) * | 2001-10-31 | 2003-05-08 | Merck & Co., Inc. | Method for treating or preventing symptoms of hormonal variation including hot flashes |
US6824786B2 (en) * | 2001-11-27 | 2004-11-30 | Ruey J. Yu | Compositions comprising phenyl-glycine derivatives |
US20040214898A1 (en) * | 2001-11-29 | 2004-10-28 | Steiner Mitchell S. | Methods for treating hot flashes |
FR2834212B1 (fr) * | 2001-12-27 | 2004-07-09 | Besins Int Belgique | Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques |
WO2003086291A2 (en) * | 2002-04-10 | 2003-10-23 | Yu Ruey J | Urea compositions |
US20060018937A1 (en) * | 2002-10-25 | 2006-01-26 | Foamix Ltd. | Steroid kit and foamable composition and uses thereof |
US20080206161A1 (en) | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
US20050020552A1 (en) * | 2003-07-16 | 2005-01-27 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
CN1930181A (zh) | 2004-01-07 | 2007-03-14 | 恩多研究公司 | 螺旋12定向的甾族药品 |
US20050181057A1 (en) * | 2004-02-13 | 2005-08-18 | Rosenberg Paul K. | Vaginal lubricant |
US20060252734A1 (en) * | 2004-09-08 | 2006-11-09 | Woodward John R | Methods of female sexual enhancement |
US20080119445A1 (en) * | 2004-09-08 | 2008-05-22 | Woodward John R | Methods of female sexual enhancement |
US20060276442A1 (en) * | 2004-09-08 | 2006-12-07 | Woodward John R | Methods of female sexual enhancement |
BRPI0516243C1 (pt) * | 2004-10-20 | 2021-05-25 | Endorecherche Inc | uso de um precursor de esteróide sexual selecionado do grupo que consiste em dehidroepiandrosterona, sulfato de dehidroepiandrosterona, androst-5-eno-3b,17b-diol e 4-androsten-3,17-diona, uso do referido precursor em 5 associação com um modulador de receptor de estrogênio seletivo para proteção uterina e da glândula mamária contra câncer, composição farmacêutica e kit |
EA200700983A1 (ru) | 2004-11-01 | 2008-04-28 | Эндорешерш, Инк. | Применение андрогенов для снижения вероятности приобретения или лечения старения кожи |
US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
CA2578790A1 (en) | 2005-12-16 | 2007-06-16 | Lyle Corporate Development, Inc. | Regeneration of vaginal tissue with non-systemic vaginal administration of estrogen |
US8021659B2 (en) * | 2006-04-28 | 2011-09-20 | Naidu Lp | Coenzyme Q10, lactoferrin and angiogenin compositions and uses thereof |
JP4179624B2 (ja) * | 2006-07-18 | 2008-11-12 | ヒロセ電機株式会社 | 平型導体用電気コネクタ |
US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
US20100317635A1 (en) | 2009-06-16 | 2010-12-16 | Endorecherche, Inc. | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
-
2008
- 2008-08-07 US US12/221,847 patent/US8268806B2/en active Active
- 2008-08-08 CA CA2820566A patent/CA2820566C/en not_active Expired - Fee Related
- 2008-08-08 JP JP2010519317A patent/JP5725283B2/ja active Active
- 2008-08-08 ES ES08783354T patent/ES2888104T3/es active Active
- 2008-08-08 BR BRPI0815353-1A patent/BRPI0815353A2/pt not_active Application Discontinuation
- 2008-08-08 NZ NZ583147A patent/NZ583147A/en unknown
- 2008-08-08 EA EA201200369A patent/EA201200369A1/ru unknown
- 2008-08-08 CN CN201510736908.3A patent/CN105412121A/zh active Pending
- 2008-08-08 KR KR1020137020819A patent/KR101638130B1/ko active IP Right Grant
- 2008-08-08 NZ NZ598270A patent/NZ598270A/xx not_active IP Right Cessation
- 2008-08-08 CA CA2696127A patent/CA2696127C/en not_active Expired - Fee Related
- 2008-08-08 SG SG2012058681A patent/SG183702A1/en unknown
- 2008-08-08 EA EA201000312A patent/EA020683B1/ru unknown
- 2008-08-08 EP EP11191361.2A patent/EP2441456B1/en active Active
- 2008-08-08 CN CN200880110988A patent/CN101861152A/zh active Pending
- 2008-08-08 EP EP08783354.7A patent/EP2185157B1/en active Active
- 2008-08-08 WO PCT/CA2008/001444 patent/WO2009021323A1/en active Application Filing
- 2008-08-08 SG SG10201601242TA patent/SG10201601242TA/en unknown
- 2008-08-08 AU AU2008286651A patent/AU2008286651B2/en active Active
- 2008-08-08 CN CN2012101093907A patent/CN102861335A/zh active Pending
- 2008-08-08 MX MX2010001627A patent/MX2010001627A/es active IP Right Grant
- 2008-08-08 SG SG10201902375XA patent/SG10201902375XA/en unknown
- 2008-08-08 KR KR1020107005355A patent/KR101680287B1/ko active IP Right Grant
- 2008-08-08 CN CN201910006969.2A patent/CN109893526A/zh active Pending
- 2008-08-08 PT PT87833547T patent/PT2185157T/pt unknown
- 2008-08-08 DK DK08783354.7T patent/DK2185157T3/da active
- 2008-08-08 KR KR1020167005962A patent/KR101850125B1/ko active IP Right Grant
- 2008-08-08 TW TW100142274A patent/TWI565468B/zh not_active IP Right Cessation
- 2008-08-08 TW TW105114301A patent/TWI609688B/zh not_active IP Right Cessation
- 2008-08-08 TW TW097130238A patent/TWI388328B/zh active
- 2008-08-10 SA SA08290494A patent/SA08290494B1/ar unknown
- 2008-08-10 SA SA111320726A patent/SA111320726B1/ar unknown
- 2008-08-11 PE PE2008001360A patent/PE20090945A1/es active IP Right Grant
- 2008-08-11 AR ARP080103498A patent/AR068702A1/es not_active Application Discontinuation
- 2008-08-11 PE PE2013001547A patent/PE20140925A1/es active IP Right Grant
-
2010
- 2010-02-04 IL IL203747A patent/IL203747A/en active Protection Beyond IP Right Term
- 2010-02-05 TN TNP2010000065A patent/TN2010000065A1/fr unknown
- 2010-03-04 CO CO10025622A patent/CO6260084A2/es not_active Application Discontinuation
- 2010-03-04 NO NO20100300A patent/NO20100300L/no not_active Application Discontinuation
- 2010-03-05 EC EC2010010016A patent/ECSP10010016A/es unknown
- 2010-03-08 MA MA32678A patent/MA31694B1/fr unknown
-
2012
- 2012-07-09 US US13/544,407 patent/US8957054B2/en active Active
- 2012-09-04 US US13/602,503 patent/US10881650B2/en active Active
- 2012-09-04 US US13/602,602 patent/US8629129B2/en active Active
-
2013
- 2013-01-09 JP JP2013001754A patent/JP6197292B2/ja active Active
- 2013-11-11 PH PH12013502291A patent/PH12013502291B1/en unknown
-
2016
- 2016-05-16 HK HK16105547.9A patent/HK1217639A1/zh unknown
-
2018
- 2018-12-26 AR ARP180103856A patent/AR114051A2/es not_active Application Discontinuation
-
2020
- 2020-11-18 US US16/951,783 patent/US20210069169A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR068702A1 (es) | Composiciones farmaceuticas | |
Gooren et al. | Endocrine treatment of aging transgender people | |
TWI283579B (en) | Pharmaceutical compositions and uses for androst-5-ene-3beta,17beta-diol | |
Pan et al. | Update on hormone therapy for the management of postmenopausal women | |
Kulkarni et al. | Role of Estrogen Treatment in the Management of Schizophrenia: Are We There Yet? | |
Labrie | Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy | |
NI201000184A (es) | Composiciones y métodos para tratar el cáncer del seno. | |
Srinivas-Shankar et al. | Drug insight: testosterone preparations | |
NZ597583A (en) | Treatment of alzheimer’s disease, loss of cognition, memory loss and dementia with sex steroid precursors in combination with selective estrogen receptor modulators | |
AR035564A1 (es) | Moduladores selectivos de receptores de estrogenos en combinacion con estrogenos | |
JP2020176149A (ja) | 性ステロイド前駆体とsermとの併用による男性アンドロゲン欠乏症状又は疾患の治療 | |
Waldman et al. | Epilepsy care in transgender patients | |
Jeong-Won et al. | A review of gender-affirming hormone therapy for transgender and gender diverse adults in South Korea | |
AR104577A2 (es) | Métodos para tratar o reducir la probabilidad de adquirir síntomas o enfermedades debidas a la menopausia | |
ES2320662T3 (es) | Hormonoterapia restitutiva y tratamiento para la depresion con dienogest. | |
Fisher et al. | Endocrine treatment of transsexual male-to-female persons | |
Roeca et al. | Menopause as a Manifestation of Aging | |
Stevenson | How to help patients through the menopause | |
Arteni et al. | Hormone replacement therapy and autoimmune diseases | |
Kennedy | Effects of steroids in women with breast cancer | |
Grossman et al. | Are hormones the answer to low libido? | |
Scholten | Medications for Menopause | |
CU20100027A7 (es) | Composiciones farmacéuticas | |
MAHONEY | NAMS Updates Statement on Hormone Therapy | |
Moghadam et al. | Advances in menopausal hormonal therapy delivery systems: a comparative review |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |