IT1304190B1 - Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche - Google Patents
Clatrati di deidroepiandrosterone e relative composizionifarmaceuticheInfo
- Publication number
- IT1304190B1 IT1304190B1 IT1998MI002745A ITMI982745A IT1304190B1 IT 1304190 B1 IT1304190 B1 IT 1304190B1 IT 1998MI002745 A IT1998MI002745 A IT 1998MI002745A IT MI982745 A ITMI982745 A IT MI982745A IT 1304190 B1 IT1304190 B1 IT 1304190B1
- Authority
- IT
- Italy
- Prior art keywords
- clatrates
- dehydroepiandrosterone
- pharmaceutical compositions
- related pharmaceutical
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1998MI002745A IT1304190B1 (it) | 1998-12-18 | 1998-12-18 | Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche |
CO99077980A CO5231137A1 (es) | 1998-12-18 | 1999-12-14 | Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes |
TW088121876A TWI225791B (en) | 1998-12-18 | 1999-12-14 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
ARP990106362A AR021663A1 (es) | 1998-12-18 | 1999-12-14 | Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes |
CA002355148A CA2355148A1 (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
IL14377699A IL143776A0 (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
ES99963559T ES2203232T3 (es) | 1998-12-18 | 1999-12-16 | Clatratos de dehidroepiandrosterona, posiblemente en forma de sulfatos. |
DE69909128T DE69909128T2 (de) | 1998-12-18 | 1999-12-16 | Einschlusskomplexe von dehydroepiandrosteron und korrespondierende pharmazeutische zusammenstellungen |
EP99963559A EP1140110B1 (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
HU0104822A HU225414B1 (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and pharmaceutical compositions thereof |
SI9930401T SI1140110T1 (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
AU19810/00A AU759979B2 (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
CNB998157716A CN1198620C (zh) | 1998-12-18 | 1999-12-16 | 脱氢表雄酮的笼形物和相应的药物组合物 |
BR9916288-1A BR9916288A (pt) | 1998-12-18 | 1999-12-16 | Clatratos de deidroepiandroesterona e correspondentes composições farmacêuticas |
TR2001/01766T TR200101766T2 (tr) | 1998-12-18 | 1999-12-16 | Dehidroepiandrosteronun klatratları ve bunlara tekabül eden kompozisyonlar |
NZ512795A NZ512795A (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
EA200100674A EA003304B1 (ru) | 1998-12-18 | 1999-12-16 | Клатраты дегидроэпиандростерона и соответствующие фармацевтические композиции |
PE1999001262A PE20001379A1 (es) | 1998-12-18 | 1999-12-16 | Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes |
JP2000589219A JP2002532565A (ja) | 1998-12-18 | 1999-12-16 | デヒドロエピアンドロステロンの包接化合物及び対応する薬学的組成物 |
PT99963559T PT1140110E (pt) | 1998-12-18 | 1999-12-16 | Clatratos de desidroepiandrosterona e correspondentes composicoes farmaceuticas |
DK99963559T DK1140110T3 (da) | 1998-12-18 | 1999-12-16 | Klatrater af dehydroepiandrosteron og korresponderende farmaceutiske sammensætninger |
KR1020017007454A KR100693514B1 (ko) | 1998-12-18 | 1999-12-16 | 데하이드로에피안드로스테론의 클라트레이트 및 상응하는약제학적 조성물 |
AT99963559T ATE243517T1 (de) | 1998-12-18 | 1999-12-16 | Einschlusskomplexe von dehydroepiandrosteron und korrespondierende pharmazeutische zusammenstellungen |
PCT/EP1999/010010 WO2000037109A2 (en) | 1998-12-18 | 1999-12-16 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions |
IL143776A IL143776A (en) | 1998-12-18 | 2001-06-14 | Calathrites of dehydroepiandrosterone and appropriate pharmaceutical preparations |
ZA200105223A ZA200105223B (en) | 1998-12-18 | 2001-06-25 | Clathrates of dehydroepiandrosterone and corresponding pharmaceutical compositions. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1998MI002745A IT1304190B1 (it) | 1998-12-18 | 1998-12-18 | Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI982745A1 ITMI982745A1 (it) | 2000-06-18 |
IT1304190B1 true IT1304190B1 (it) | 2001-03-08 |
Family
ID=11381280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT1998MI002745A IT1304190B1 (it) | 1998-12-18 | 1998-12-18 | Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1140110B1 (it) |
JP (1) | JP2002532565A (it) |
KR (1) | KR100693514B1 (it) |
CN (1) | CN1198620C (it) |
AR (1) | AR021663A1 (it) |
AT (1) | ATE243517T1 (it) |
AU (1) | AU759979B2 (it) |
BR (1) | BR9916288A (it) |
CA (1) | CA2355148A1 (it) |
CO (1) | CO5231137A1 (it) |
DE (1) | DE69909128T2 (it) |
DK (1) | DK1140110T3 (it) |
EA (1) | EA003304B1 (it) |
ES (1) | ES2203232T3 (it) |
HU (1) | HU225414B1 (it) |
IL (2) | IL143776A0 (it) |
IT (1) | IT1304190B1 (it) |
NZ (1) | NZ512795A (it) |
PE (1) | PE20001379A1 (it) |
PT (1) | PT1140110E (it) |
TR (1) | TR200101766T2 (it) |
TW (1) | TWI225791B (it) |
WO (1) | WO2000037109A2 (it) |
ZA (1) | ZA200105223B (it) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2815860B1 (fr) * | 2000-10-26 | 2003-12-12 | Oreal | Composition, notamment cosmetique, comprenant la dhea et/ou precurseur ou derive de celle-ci et au moins un agent myorelaxant |
EP1285927A3 (de) * | 2001-08-16 | 2005-06-29 | Schering Aktiengesellschaft | Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems |
ITMI20021074A1 (it) * | 2002-05-20 | 2003-11-20 | Actimex S R L | Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione |
ITMI20022549A1 (it) * | 2002-12-02 | 2004-06-03 | Actimex S R L | Composizione quaternaria comprendente come sostanza attiva la propolis. |
MXPA06011031A (es) | 2004-04-01 | 2007-03-21 | Hoffmann La Roche | Complejos de inclusiones de ciclodextrina de pirimidin-2,4,6-trionas. |
JPWO2006137433A1 (ja) * | 2005-06-21 | 2009-01-22 | わかもと製薬株式会社 | レボカバスチンを可溶化させた水性薬剤 |
ITPD20050224A1 (it) * | 2005-07-19 | 2007-01-20 | Actimex Srl | Composizioni contenenti micronutrienti aventi in particolare attivita' antiossidante e loro impiego |
US8268806B2 (en) * | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
RU2627111C2 (ru) * | 2011-07-19 | 2017-08-03 | Пантархей Байосайенс Б.В. | Таблетка, содержащая дегидроэпиандростерон (дгэа) |
DE102012101680A1 (de) * | 2012-02-29 | 2013-08-29 | Aicuris Gmbh & Co. Kg | Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat |
WO2014172706A1 (en) * | 2013-04-19 | 2014-10-23 | University Of Houston System | Cocrystalline dhea formulations |
EP3505154B1 (en) | 2017-12-26 | 2022-04-06 | Industrial Technology Research Institute | Composition for improving the solubility of poorly soluble substances, use thereof and complex formulation containing thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2647343B1 (fr) * | 1989-05-24 | 1994-05-06 | Rhone Poulenc Sante | Nouvelle forme pharmaceutique poreuse et sa preparation |
US4978532A (en) * | 1989-08-11 | 1990-12-18 | Pharmedic Co. | Dosage form for administration of dehydroepiandrosterone |
US5120720A (en) * | 1990-09-20 | 1992-06-09 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Preparation of lipophile:hydroxypropylcyclodextrin complexes by a method using co-solubilizers |
WO1994004155A1 (en) * | 1992-08-19 | 1994-03-03 | Health Resource Institute, Ltd. | Dehydroepiandrosterone therapy for the treatment of eye disorders |
WO1995015746A1 (en) * | 1993-12-10 | 1995-06-15 | The School Of Pharmacy | Liposome delivery systems |
CA2237023C (en) * | 1995-11-13 | 2008-02-19 | Supergen, Inc. | Improved formulation for administration of steroid compounds |
-
1998
- 1998-12-18 IT IT1998MI002745A patent/IT1304190B1/it active
-
1999
- 1999-12-14 AR ARP990106362A patent/AR021663A1/es not_active Application Discontinuation
- 1999-12-14 TW TW088121876A patent/TWI225791B/zh not_active IP Right Cessation
- 1999-12-14 CO CO99077980A patent/CO5231137A1/es not_active Application Discontinuation
- 1999-12-16 NZ NZ512795A patent/NZ512795A/en unknown
- 1999-12-16 DE DE69909128T patent/DE69909128T2/de not_active Expired - Fee Related
- 1999-12-16 CA CA002355148A patent/CA2355148A1/en not_active Abandoned
- 1999-12-16 PT PT99963559T patent/PT1140110E/pt unknown
- 1999-12-16 JP JP2000589219A patent/JP2002532565A/ja active Pending
- 1999-12-16 TR TR2001/01766T patent/TR200101766T2/xx unknown
- 1999-12-16 EA EA200100674A patent/EA003304B1/ru not_active IP Right Cessation
- 1999-12-16 CN CNB998157716A patent/CN1198620C/zh not_active Expired - Fee Related
- 1999-12-16 WO PCT/EP1999/010010 patent/WO2000037109A2/en active IP Right Grant
- 1999-12-16 BR BR9916288-1A patent/BR9916288A/pt not_active IP Right Cessation
- 1999-12-16 AU AU19810/00A patent/AU759979B2/en not_active Ceased
- 1999-12-16 IL IL14377699A patent/IL143776A0/xx not_active IP Right Cessation
- 1999-12-16 KR KR1020017007454A patent/KR100693514B1/ko not_active IP Right Cessation
- 1999-12-16 AT AT99963559T patent/ATE243517T1/de not_active IP Right Cessation
- 1999-12-16 EP EP99963559A patent/EP1140110B1/en not_active Expired - Lifetime
- 1999-12-16 DK DK99963559T patent/DK1140110T3/da active
- 1999-12-16 ES ES99963559T patent/ES2203232T3/es not_active Expired - Lifetime
- 1999-12-16 HU HU0104822A patent/HU225414B1/hu not_active IP Right Cessation
- 1999-12-16 PE PE1999001262A patent/PE20001379A1/es not_active Application Discontinuation
-
2001
- 2001-06-14 IL IL143776A patent/IL143776A/en unknown
- 2001-06-25 ZA ZA200105223A patent/ZA200105223B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU1981000A (en) | 2000-07-12 |
JP2002532565A (ja) | 2002-10-02 |
EA003304B1 (ru) | 2003-04-24 |
PT1140110E (pt) | 2003-11-28 |
ZA200105223B (en) | 2002-09-25 |
IL143776A (en) | 2007-03-08 |
TWI225791B (en) | 2005-01-01 |
WO2000037109A3 (en) | 2000-09-14 |
CA2355148A1 (en) | 2000-06-29 |
EP1140110A2 (en) | 2001-10-10 |
HUP0104822A3 (en) | 2002-08-28 |
HU225414B1 (en) | 2006-11-28 |
BR9916288A (pt) | 2001-10-16 |
WO2000037109A2 (en) | 2000-06-29 |
TR200101766T2 (tr) | 2001-12-21 |
EP1140110B1 (en) | 2003-06-25 |
ITMI982745A1 (it) | 2000-06-18 |
ATE243517T1 (de) | 2003-07-15 |
IL143776A0 (en) | 2002-04-21 |
DE69909128T2 (de) | 2004-05-06 |
HUP0104822A2 (hu) | 2002-05-29 |
CO5231137A1 (es) | 2002-12-27 |
CN1198620C (zh) | 2005-04-27 |
KR20010086109A (ko) | 2001-09-07 |
PE20001379A1 (es) | 2000-11-25 |
NZ512795A (en) | 2003-08-29 |
KR100693514B1 (ko) | 2007-03-14 |
ES2203232T3 (es) | 2004-04-01 |
AU759979B2 (en) | 2003-05-01 |
DE69909128D1 (de) | 2003-07-31 |
CN1333686A (zh) | 2002-01-30 |
EA200100674A1 (ru) | 2001-12-24 |
AR021663A1 (es) | 2002-07-31 |
DK1140110T3 (da) | 2003-10-20 |
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