AR021663A1 - Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes - Google Patents
Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientesInfo
- Publication number
- AR021663A1 AR021663A1 ARP990106362A ARP990106362A AR021663A1 AR 021663 A1 AR021663 A1 AR 021663A1 AR P990106362 A ARP990106362 A AR P990106362A AR P990106362 A ARP990106362 A AR P990106362A AR 021663 A1 AR021663 A1 AR 021663A1
- Authority
- AR
- Argentina
- Prior art keywords
- dehydroepiandrosterone
- clarrates
- corresponding pharmaceutical
- pharmaceutical compositions
- insufficiencies
- Prior art date
Links
- FMGSKLZLMKYGDP-UHFFFAOYSA-N Dehydroepiandrosterone Natural products C1C(O)CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CC=C21 FMGSKLZLMKYGDP-UHFFFAOYSA-N 0.000 title abstract 2
- FMGSKLZLMKYGDP-USOAJAOKSA-N dehydroepiandrosterone Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC=C21 FMGSKLZLMKYGDP-USOAJAOKSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229960002847 prasterone Drugs 0.000 title abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 208000017515 adrenocortical insufficiency Diseases 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000009256 replacement therapy Methods 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- 238000005063 solubilization Methods 0.000 abstract 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pregnancy & Childbirth (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invencion se refiere a clatratos de dehidroepiandrosterona, posiblemente en la forma de sulfatos, en una matriz que consiste de unaciclodextrina y opcionalmente comprende un agente de co-solubilizacion, y la correspondiente composicion farmacéutica adecuada para terapias de sustitucionpara el tratamiento de insuficiencias adrenocorticales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998MI002745A IT1304190B1 (it) | 1998-12-18 | 1998-12-18 | Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR021663A1 true AR021663A1 (es) | 2002-07-31 |
Family
ID=11381280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990106362A AR021663A1 (es) | 1998-12-18 | 1999-12-14 | Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1140110B1 (es) |
| JP (1) | JP2002532565A (es) |
| KR (1) | KR100693514B1 (es) |
| CN (1) | CN1198620C (es) |
| AR (1) | AR021663A1 (es) |
| AT (1) | ATE243517T1 (es) |
| AU (1) | AU759979B2 (es) |
| BR (1) | BR9916288A (es) |
| CA (1) | CA2355148A1 (es) |
| CO (1) | CO5231137A1 (es) |
| DE (1) | DE69909128T2 (es) |
| DK (1) | DK1140110T3 (es) |
| EA (1) | EA003304B1 (es) |
| ES (1) | ES2203232T3 (es) |
| HU (1) | HU225414B1 (es) |
| IL (2) | IL143776A0 (es) |
| IT (1) | IT1304190B1 (es) |
| NZ (1) | NZ512795A (es) |
| PE (1) | PE20001379A1 (es) |
| PT (1) | PT1140110E (es) |
| TR (1) | TR200101766T2 (es) |
| TW (1) | TWI225791B (es) |
| WO (1) | WO2000037109A2 (es) |
| ZA (1) | ZA200105223B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2815860B1 (fr) * | 2000-10-26 | 2003-12-12 | Oreal | Composition, notamment cosmetique, comprenant la dhea et/ou precurseur ou derive de celle-ci et au moins un agent myorelaxant |
| EP1285927A3 (de) * | 2001-08-16 | 2005-06-29 | Schering Aktiengesellschaft | Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems |
| ITMI20021074A1 (it) * | 2002-05-20 | 2003-11-20 | Actimex S R L | Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione |
| ITMI20022549A1 (it) * | 2002-12-02 | 2004-06-03 | Actimex S R L | Composizione quaternaria comprendente come sostanza attiva la propolis. |
| KR100771411B1 (ko) | 2004-04-01 | 2007-10-30 | 에프. 호프만-라 로슈 아게 | 피리미딘-2,4,6-트리온의 시클로덱스트린 포접 복합체 |
| WO2006137433A1 (ja) * | 2005-06-21 | 2006-12-28 | Wakamoto Pharmaceutical Co., Ltd. | レボカバスチンを可溶化させた水性薬剤 |
| ITPD20050224A1 (it) * | 2005-07-19 | 2007-01-20 | Actimex Srl | Composizioni contenenti micronutrienti aventi in particolare attivita' antiossidante e loro impiego |
| US8268806B2 (en) * | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
| HUE025350T2 (en) * | 2011-07-19 | 2016-02-29 | Pantarhei Bioscience Bv | Tablets containing dehydroepiandrosterone (DHEA) |
| DE102012101680A1 (de) * | 2012-02-29 | 2013-08-29 | Aicuris Gmbh & Co. Kg | Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat |
| WO2014172706A1 (en) * | 2013-04-19 | 2014-10-23 | University Of Houston System | Cocrystalline dhea formulations |
| ES2914305T3 (es) * | 2017-12-26 | 2022-06-09 | Ind Tech Res Inst | Composición para mejorar la solubilidad de sustancias poco solubles, uso de la misma y formulación compleja que contiene la misma |
| EP3666260A1 (en) * | 2018-12-13 | 2020-06-17 | Laboratorios Leon Farma SA | Ethinyl estradiol-beta-cyclodextrin complex and process for preparing thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2647343B1 (fr) * | 1989-05-24 | 1994-05-06 | Rhone Poulenc Sante | Nouvelle forme pharmaceutique poreuse et sa preparation |
| US4978532A (en) * | 1989-08-11 | 1990-12-18 | Pharmedic Co. | Dosage form for administration of dehydroepiandrosterone |
| US5120720A (en) * | 1990-09-20 | 1992-06-09 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Preparation of lipophile:hydroxypropylcyclodextrin complexes by a method using co-solubilizers |
| WO1994004155A1 (en) * | 1992-08-19 | 1994-03-03 | Health Resource Institute, Ltd. | Dehydroepiandrosterone therapy for the treatment of eye disorders |
| WO1995015746A1 (en) * | 1993-12-10 | 1995-06-15 | The School Of Pharmacy | Liposome delivery systems |
| IL124001A (en) * | 1995-11-13 | 2004-07-25 | Supergen Inc | Composition for administration of steroids |
-
1998
- 1998-12-18 IT IT1998MI002745A patent/IT1304190B1/it active
-
1999
- 1999-12-14 TW TW088121876A patent/TWI225791B/zh not_active IP Right Cessation
- 1999-12-14 CO CO99077980A patent/CO5231137A1/es not_active Application Discontinuation
- 1999-12-14 AR ARP990106362A patent/AR021663A1/es not_active Application Discontinuation
- 1999-12-16 NZ NZ512795A patent/NZ512795A/en unknown
- 1999-12-16 IL IL14377699A patent/IL143776A0/xx not_active IP Right Cessation
- 1999-12-16 CA CA002355148A patent/CA2355148A1/en not_active Abandoned
- 1999-12-16 BR BR9916288-1A patent/BR9916288A/pt not_active IP Right Cessation
- 1999-12-16 CN CNB998157716A patent/CN1198620C/zh not_active Expired - Fee Related
- 1999-12-16 JP JP2000589219A patent/JP2002532565A/ja active Pending
- 1999-12-16 KR KR1020017007454A patent/KR100693514B1/ko not_active Expired - Fee Related
- 1999-12-16 EA EA200100674A patent/EA003304B1/ru not_active IP Right Cessation
- 1999-12-16 TR TR2001/01766T patent/TR200101766T2/xx unknown
- 1999-12-16 EP EP99963559A patent/EP1140110B1/en not_active Expired - Lifetime
- 1999-12-16 AU AU19810/00A patent/AU759979B2/en not_active Ceased
- 1999-12-16 PE PE1999001262A patent/PE20001379A1/es not_active Application Discontinuation
- 1999-12-16 WO PCT/EP1999/010010 patent/WO2000037109A2/en not_active Ceased
- 1999-12-16 DK DK99963559T patent/DK1140110T3/da active
- 1999-12-16 HU HU0104822A patent/HU225414B1/hu not_active IP Right Cessation
- 1999-12-16 ES ES99963559T patent/ES2203232T3/es not_active Expired - Lifetime
- 1999-12-16 AT AT99963559T patent/ATE243517T1/de not_active IP Right Cessation
- 1999-12-16 DE DE69909128T patent/DE69909128T2/de not_active Expired - Fee Related
- 1999-12-16 PT PT99963559T patent/PT1140110E/pt unknown
-
2001
- 2001-06-14 IL IL143776A patent/IL143776A/en unknown
- 2001-06-25 ZA ZA200105223A patent/ZA200105223B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI982745A1 (it) | 2000-06-18 |
| HU225414B1 (en) | 2006-11-28 |
| WO2000037109A3 (en) | 2000-09-14 |
| NZ512795A (en) | 2003-08-29 |
| HUP0104822A3 (en) | 2002-08-28 |
| AU759979B2 (en) | 2003-05-01 |
| DK1140110T3 (da) | 2003-10-20 |
| DE69909128T2 (de) | 2004-05-06 |
| JP2002532565A (ja) | 2002-10-02 |
| IL143776A0 (en) | 2002-04-21 |
| PE20001379A1 (es) | 2000-11-25 |
| ATE243517T1 (de) | 2003-07-15 |
| EA003304B1 (ru) | 2003-04-24 |
| CA2355148A1 (en) | 2000-06-29 |
| TR200101766T2 (tr) | 2001-12-21 |
| EP1140110B1 (en) | 2003-06-25 |
| CO5231137A1 (es) | 2002-12-27 |
| KR20010086109A (ko) | 2001-09-07 |
| WO2000037109A2 (en) | 2000-06-29 |
| IT1304190B1 (it) | 2001-03-08 |
| AU1981000A (en) | 2000-07-12 |
| PT1140110E (pt) | 2003-11-28 |
| CN1333686A (zh) | 2002-01-30 |
| EP1140110A2 (en) | 2001-10-10 |
| DE69909128D1 (de) | 2003-07-31 |
| BR9916288A (pt) | 2001-10-16 |
| IL143776A (en) | 2007-03-08 |
| ES2203232T3 (es) | 2004-04-01 |
| EA200100674A1 (ru) | 2001-12-24 |
| CN1198620C (zh) | 2005-04-27 |
| TWI225791B (en) | 2005-01-01 |
| ZA200105223B (en) | 2002-09-25 |
| KR100693514B1 (ko) | 2007-03-14 |
| HUP0104822A2 (hu) | 2002-05-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR032204A1 (es) | Complejos de inclusion de ciclodextrina-drospirenona | |
| MXPA03003511A (es) | Composicion topica que contiene al menos una vitamina d o un analogo de vitamina de y al menos un corticosteroide. | |
| ES2173978T3 (es) | Utilizacion de un alcohol graso insaturado. | |
| UY28213A1 (es) | Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos. | |
| GT200100152A (es) | Nueva composicion farmaceutica para el tratamiento de la obesidad. | |
| CR9597A (es) | Formulaciones de estrogenos conjugados y bazedoxifeno | |
| GT200200114A (es) | Champues con alcohol de behenilo | |
| ES2177295T3 (es) | Parche transdermal tipo matriz para hormonas esteroides. | |
| ES2162319T3 (es) | Uso del agente quelante clioquinol para la fabricacion de una composicion farmaceutica para el tratamiento de la enfermedad de alzheimer. | |
| AR057060A1 (es) | Composiciones de tanaproget que contienen etinil estradiol | |
| AR036640A1 (es) | Formulaciones y uso de las mismas | |
| BRPI0411770A (pt) | dispositivo aperfeiçoado de distribuição | |
| PE20080400A1 (es) | Composicion farmaceutica para la anticoncepcion y para reducir el riesgo de malformaciones congenitas | |
| GT200600307A (es) | Formas de dosificacion de liberacion retardada oral altamente biodisponibles de succinato de o-desmetilvenlafaxina | |
| BRPI0508359A (pt) | composições de pelìcula | |
| BR112022019223A2 (pt) | Formulação de complexo de inclusão em ciclodextrina (cd), complexo de inclusão em ciclodextrina (cd), uso da formulação de complexo de inclusão em ciclodextrina (cd), uso de um veículo de entrega de um complexo de inclusão em ciclodextrina, método para o tratamento oral de uma disfunção, método para o tratamento oral de um humano, uso da composição, composição e método de tratamento de um transtorno das vias aéreas | |
| EP1469886B8 (en) | Lyophilized pharmaceutical composition of propofol | |
| BR9916288A (pt) | Clatratos de deidroepiandroesterona e correspondentes composições farmacêuticas | |
| PA8571901A1 (es) | Nueva composicion farmaceutica | |
| AR030140A1 (es) | Composiciones derivadas de la 2-piridinamina y metodos relacionados | |
| UY26171A1 (es) | Método y formulación farmacéutica para el tratamiento de la discinesia de aparición tardía | |
| ES2188894T3 (es) | Lactonas macrociclicas perfumadas. | |
| AR043013A1 (es) | Composicion farmaceutica destinada al tratamiento de la endometriosis | |
| AR047480A1 (es) | Composicion para la prevencion y/o tratamiento de enfermedades metabolicas oseas; proceso de preparacion y uso de esta composicion | |
| AR036679A1 (es) | Formulaciones y uso de las mismas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |