NI201000184A - Composiciones y métodos para tratar el cáncer del seno. - Google Patents

Composiciones y métodos para tratar el cáncer del seno.

Info

Publication number
NI201000184A
NI201000184A NI201000184A NI201000184A NI201000184A NI 201000184 A NI201000184 A NI 201000184A NI 201000184 A NI201000184 A NI 201000184A NI 201000184 A NI201000184 A NI 201000184A NI 201000184 A NI201000184 A NI 201000184A
Authority
NI
Nicaragua
Prior art keywords
methods
breast cancer
antiprogestin
instant invention
low
Prior art date
Application number
NI201000184A
Other languages
English (en)
Inventor
Podolski Joseph
D Wiehle Ronald
Original Assignee
Repros Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40758440&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NI201000184(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc
Publication of NI201000184A publication Critical patent/NI201000184A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención instantánea se relaciona con métodos de uso de antiprogestinas para tratar el cáncer del seno sensible a hormonas en una mujer. Más específicamente, la invención instantánea utiliza antiprogestinas con poca afinidad por el receptor de glucocorticoides y baja actividad estrogénica/antiestrogénica para suprimir la proliferación de tejido del seno. La antiprogestina puede ser una antiprogestina pura o un modulador selectivo de los receptores de la progesterona (SPRM), siempre que la antiprogestina tenga poca afinidad por el receptor de glucocorticoides y que se administre en una cantidad efectiva para suprimir la proliferación de tejido del seno. Los métodos de la invención instantánea también pueden usarse para prevenir la hiperproliferación y el desarrollo de cáncer del seno posterior en pacientes que reciben tratamientos hormonales, como la terapia de reemplazo hormonal menopáusica. aromatasa.
NI201000184A 2008-04-28 2010-10-27 Composiciones y métodos para tratar el cáncer del seno. NI201000184A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4845208P 2008-04-28 2008-04-28

Publications (1)

Publication Number Publication Date
NI201000184A true NI201000184A (es) 2011-08-10

Family

ID=40758440

Family Applications (1)

Application Number Title Priority Date Filing Date
NI201000184A NI201000184A (es) 2008-04-28 2010-10-27 Composiciones y métodos para tratar el cáncer del seno.

Country Status (22)

Country Link
US (2) US20110053900A1 (es)
EP (2) EP2293798A1 (es)
JP (1) JP5576362B2 (es)
KR (1) KR101349737B1 (es)
CN (1) CN102099040B (es)
AR (1) AR071419A1 (es)
AU (1) AU2009241360B2 (es)
BR (1) BRPI0911112A2 (es)
CA (1) CA2722637C (es)
CL (1) CL2009001011A1 (es)
EA (1) EA019224B1 (es)
HK (1) HK1155084A1 (es)
IL (2) IL208845A (es)
ME (1) ME01122B (es)
MX (1) MX2010011273A (es)
MY (1) MY161549A (es)
NI (1) NI201000184A (es)
NZ (1) NZ589534A (es)
TW (1) TWI539953B (es)
UA (1) UA101192C2 (es)
WO (1) WO2009134723A1 (es)
ZA (1) ZA201007648B (es)

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UA113283C2 (xx) * 2010-12-23 2017-01-10 19-норстероїди і їх застосування для лікування прогестеронзалежних станів
KR102009007B1 (ko) 2011-10-04 2019-08-08 인비비스 파마슈티컬스 인코포레이티드 항-프로게스틴 민감성 종양을 확인하고 치료하기 위한 방법 및 시스템
FR2997628B1 (fr) * 2012-11-08 2015-01-16 Hra Pharma Lab Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone
CN109908355B (zh) * 2013-03-15 2022-11-15 阿普雷奇亚制药有限责任公司 包含左乙拉西坦的快速分散剂型
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
HU230381B1 (hu) * 2014-02-17 2016-03-29 Richter Gedeon Nyrt Ipari eljárás szteroid intermedier előállítására
US10786461B2 (en) 2014-11-17 2020-09-29 Context Biopharma Inc. Onapristone extended-release compositions and methods
BR112018005999A2 (pt) 2015-09-25 2019-01-08 Context Biopharma Inc métodos para a produção de intermediários de onapristona
KR20180113988A (ko) 2015-12-15 2018-10-17 컨텍스트 바이오파마 인코포레이티드 비정질 오나프리스톤 조성물 및 그 제조방법
RS65129B1 (sr) 2016-03-28 2024-02-29 Incyte Corp Jedinjenja pirolotriazina kao inhibitori tam
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
WO2018106914A1 (en) * 2016-12-09 2018-06-14 Repros Therapeutics Inc. Oral pharmaceutical compositions comprising an unmicronized selective progesterone receptor as active agent
AU2019293618A1 (en) 2018-06-29 2021-02-18 Incyte Corporation Formulations of an AXL/MER inhibitor
RU2679625C1 (ru) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ

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Also Published As

Publication number Publication date
CL2009001011A1 (es) 2009-09-25
CA2722637A1 (en) 2009-11-05
IL208845A0 (en) 2011-01-31
MY161549A (en) 2017-04-28
ME01122B (me) 2013-03-20
ZA201007648B (en) 2011-07-27
EA201071250A1 (ru) 2011-04-29
KR20110003553A (ko) 2011-01-12
US20110053900A1 (en) 2011-03-03
TW201002330A (en) 2010-01-16
AU2009241360A1 (en) 2009-11-05
CN102099040A (zh) 2011-06-15
CN102099040B (zh) 2013-06-19
MX2010011273A (es) 2010-12-21
US20140343022A1 (en) 2014-11-20
HK1155084A1 (en) 2012-05-11
IL208845A (en) 2016-08-31
CA2722637C (en) 2015-03-10
UA101192C2 (uk) 2013-03-11
WO2009134723A9 (en) 2010-01-21
EA019224B1 (ru) 2014-02-28
IL247093A0 (en) 2016-09-29
TWI539953B (zh) 2016-07-01
EP2293798A1 (en) 2011-03-16
AR071419A1 (es) 2010-06-16
AU2009241360B2 (en) 2012-03-08
JP5576362B2 (ja) 2014-08-20
KR101349737B1 (ko) 2014-02-07
BRPI0911112A2 (pt) 2015-10-06
WO2009134723A1 (en) 2009-11-05
JP2011518883A (ja) 2011-06-30
EP2974772A1 (en) 2016-01-20
NZ589534A (en) 2012-08-31

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