AR059178A1 - Benzotiazoles heteroaril sustituidos, composiciones farmaceuticas que los contienen,y usos terapeuticos, entre ellos, en el tratamiento y/o prevencion de la enfermedad de alzheimer. - Google Patents

Benzotiazoles heteroaril sustituidos, composiciones farmaceuticas que los contienen,y usos terapeuticos, entre ellos, en el tratamiento y/o prevencion de la enfermedad de alzheimer.

Info

Publication number
AR059178A1
AR059178A1 ARP070100305A ARP070100305A AR059178A1 AR 059178 A1 AR059178 A1 AR 059178A1 AR P070100305 A ARP070100305 A AR P070100305A AR P070100305 A ARP070100305 A AR P070100305A AR 059178 A1 AR059178 A1 AR 059178A1
Authority
AR
Argentina
Prior art keywords
alkyl
fluororalkyl
3alkyl
alkylene
fluoralkyl
Prior art date
Application number
ARP070100305A
Other languages
English (en)
Spanish (es)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38309497&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR059178(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR059178A1 publication Critical patent/AR059178A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ARP070100305A 2006-01-27 2007-01-24 Benzotiazoles heteroaril sustituidos, composiciones farmaceuticas que los contienen,y usos terapeuticos, entre ellos, en el tratamiento y/o prevencion de la enfermedad de alzheimer. AR059178A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76265406P 2006-01-27 2006-01-27

Publications (1)

Publication Number Publication Date
AR059178A1 true AR059178A1 (es) 2008-03-12

Family

ID=38309497

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070100305A AR059178A1 (es) 2006-01-27 2007-01-24 Benzotiazoles heteroaril sustituidos, composiciones farmaceuticas que los contienen,y usos terapeuticos, entre ellos, en el tratamiento y/o prevencion de la enfermedad de alzheimer.

Country Status (20)

Country Link
US (2) US8163928B2 (cg-RX-API-DMAC7.html)
EP (1) EP1981883A4 (cg-RX-API-DMAC7.html)
JP (1) JP5289061B2 (cg-RX-API-DMAC7.html)
KR (1) KR101406248B1 (cg-RX-API-DMAC7.html)
CN (1) CN101410393B (cg-RX-API-DMAC7.html)
AR (1) AR059178A1 (cg-RX-API-DMAC7.html)
AU (1) AU2007207904C1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0707283A2 (cg-RX-API-DMAC7.html)
CA (1) CA2640213A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP088645A (cg-RX-API-DMAC7.html)
IL (1) IL192876A0 (cg-RX-API-DMAC7.html)
NO (1) NO20083394L (cg-RX-API-DMAC7.html)
NZ (1) NZ569667A (cg-RX-API-DMAC7.html)
RU (1) RU2448106C2 (cg-RX-API-DMAC7.html)
SA (1) SA07280009B1 (cg-RX-API-DMAC7.html)
TW (2) TW201018678A (cg-RX-API-DMAC7.html)
UA (1) UA95267C2 (cg-RX-API-DMAC7.html)
UY (1) UY30112A1 (cg-RX-API-DMAC7.html)
WO (1) WO2007086800A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200806075B (cg-RX-API-DMAC7.html)

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WO2011163636A2 (en) * 2010-06-24 2011-12-29 The Regents Of The University Of California Compounds and uses thereof in modulating levels of various amyloid beta peptide alloforms
WO2012145169A2 (en) * 2011-04-21 2012-10-26 The Regents Of The University Of California Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles
WO2013040183A1 (en) * 2011-09-16 2013-03-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Beta-amyloid imaging agents, methods of manufacture, and methods of use thereof
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KR102053484B1 (ko) * 2012-12-21 2019-12-06 국립연구개발법인 양자과학기술연구개발기구 뇌 안에 축적된 타우 단백질을 이미징하기 위한 신규한 화합물
EP2968296B1 (en) 2013-03-12 2020-09-02 The Regents of the University of California Gamma-secretase modulators
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JP2017537916A (ja) * 2014-12-02 2017-12-21 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 有害生物防除剤としての二環式化合物
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CA3100235A1 (en) 2018-05-16 2019-11-21 Emory University Styrylbenzothiazole derivatives and uses in imaging
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GB201914989D0 (en) * 2019-10-16 2019-11-27 Karin & Sten Mortstedt Cbd Solutions Ab Selective ligands for TAU Aggregates
CA3161455A1 (en) 2019-11-13 2021-05-20 Aprinoia Therapeutics Limited Compounds for degrading tau protein aggregates and uses thereof
KR102682408B1 (ko) * 2021-05-12 2024-07-05 에이치케이이노엔 주식회사 신규한 벤조티아졸 유도체, 이의 제조방법 및 이의 간질환 예방 또는 치료 용도
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CN114380731B (zh) * 2022-03-09 2024-07-02 台州学院 一种kcnq钾离子通道激动剂、药物组合物及其应用
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Also Published As

Publication number Publication date
RU2448106C2 (ru) 2012-04-20
TW201018678A (en) 2010-05-16
JP5289061B2 (ja) 2013-09-11
KR20080090542A (ko) 2008-10-08
ECSP088645A (es) 2008-08-29
EP1981883A1 (en) 2008-10-22
NZ569667A (en) 2011-09-30
TW200736252A (en) 2007-10-01
EP1981883A4 (en) 2010-10-06
WO2007086800A1 (en) 2007-08-02
AU2007207904C1 (en) 2011-10-13
US8163928B2 (en) 2012-04-24
NO20083394L (no) 2008-10-02
IL192876A0 (en) 2009-02-11
ZA200806075B (en) 2012-12-27
UY30112A1 (es) 2007-08-31
RU2008130965A (ru) 2010-03-10
US20090028787A1 (en) 2009-01-29
US20120207679A1 (en) 2012-08-16
UA95267C2 (en) 2011-07-25
US8957215B2 (en) 2015-02-17
AU2007207904B2 (en) 2011-03-10
SA07280009B1 (ar) 2011-07-20
CA2640213A1 (en) 2007-08-02
CN101410393A (zh) 2009-04-15
BRPI0707283A2 (pt) 2011-04-26
KR101406248B1 (ko) 2014-06-19
CN101410393B (zh) 2012-01-25
JP2009528271A (ja) 2009-08-06
AU2007207904A1 (en) 2007-08-02

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