AR040721A1 - Metodos y formas de dosificacion para l aliberacion controlada de paliperidona - Google Patents

Metodos y formas de dosificacion para l aliberacion controlada de paliperidona

Info

Publication number
AR040721A1
AR040721A1 AR20030102717A ARP030102717A AR040721A1 AR 040721 A1 AR040721 A1 AR 040721A1 AR 20030102717 A AR20030102717 A AR 20030102717A AR P030102717 A ARP030102717 A AR P030102717A AR 040721 A1 AR040721 A1 AR 040721A1
Authority
AR
Argentina
Prior art keywords
paliperidone
methods
plasma
dosage
takes place
Prior art date
Application number
AR20030102717A
Other languages
English (en)
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31191280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR040721(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of AR040721A1 publication Critical patent/AR040721A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Formas de dosificación y los métodos para suministrar una velocidad de liberación de paliperidona sustancialmente ascendente. Las formas de dosificación de liberación sostenida proveen concentraciones promedio de paliperidona en plasma en el estado estacionario terapéuticamente efectivas cuando se administran una vez al día. Este régimen de dosificación de una vez al día da como resultado la existencia de sólo una concentración plasmática pico de paliperidona en cada período de 24 horas. Además, la concentración pico de paliperidona en plasma tiene lugar a un tiempo posterior después de la administración de la dosis, y muestra una magnitud inferior a la concnetración pico de paliperidona en plasma que tiene lugar luego de la administración de paliperidona en una forma de dosificación de liberación inmediata.
AR20030102717A 2002-07-29 2003-07-29 Metodos y formas de dosificacion para l aliberacion controlada de paliperidona AR040721A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39959002P 2002-07-29 2002-07-29
US40600502P 2002-08-26 2002-08-26

Publications (1)

Publication Number Publication Date
AR040721A1 true AR040721A1 (es) 2005-04-20

Family

ID=31191280

Family Applications (1)

Application Number Title Priority Date Filing Date
AR20030102717A AR040721A1 (es) 2002-07-29 2003-07-29 Metodos y formas de dosificacion para l aliberacion controlada de paliperidona

Country Status (29)

Country Link
US (1) US20040092534A1 (es)
EP (1) EP1539115B1 (es)
JP (1) JP4500679B2 (es)
KR (1) KR100699516B1 (es)
CN (1) CN1684670A (es)
AR (1) AR040721A1 (es)
AT (1) ATE373472T1 (es)
AU (1) AU2003256844A1 (es)
BR (1) BR0313139A (es)
CA (1) CA2494234C (es)
CO (1) CO5580742A2 (es)
CY (1) CY1107096T1 (es)
DE (1) DE60316454T2 (es)
DK (1) DK1539115T3 (es)
ES (1) ES2293039T3 (es)
HK (1) HK1072559A1 (es)
HR (1) HRP20050077B1 (es)
IL (1) IL166489A (es)
MX (1) MXPA05001191A (es)
MY (1) MY137049A (es)
NO (1) NO324821B1 (es)
NZ (1) NZ570198A (es)
PE (1) PE20040132A1 (es)
PL (1) PL210119B1 (es)
PT (1) PT1539115E (es)
RU (1) RU2321391C2 (es)
TW (1) TWI363637B (es)
WO (1) WO2004010981A1 (es)
ZA (1) ZA200501641B (es)

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Also Published As

Publication number Publication date
NO20050956L (no) 2005-04-27
ZA200501641B (en) 2005-08-31
JP4500679B2 (ja) 2010-07-14
ES2293039T3 (es) 2008-03-16
KR20050044895A (ko) 2005-05-13
DK1539115T3 (da) 2008-01-28
HK1072559A1 (en) 2005-09-02
MXPA05001191A (es) 2005-09-12
DE60316454D1 (de) 2007-10-31
WO2004010981A1 (en) 2004-02-05
US20040092534A1 (en) 2004-05-13
PE20040132A1 (es) 2004-03-06
AU2003256844A1 (en) 2004-02-16
MY137049A (en) 2008-12-31
EP1539115A1 (en) 2005-06-15
RU2005102105A (ru) 2005-08-10
PT1539115E (pt) 2008-01-14
CY1107096T1 (el) 2012-10-24
PL210119B1 (pl) 2011-12-30
CA2494234C (en) 2009-10-27
HRP20050077B1 (hr) 2013-11-22
NZ570198A (en) 2010-01-29
IL166489A0 (en) 2006-01-15
HRP20050077A2 (en) 2005-12-31
BR0313139A (pt) 2005-07-05
CO5580742A2 (es) 2005-11-30
KR100699516B1 (ko) 2007-03-26
DE60316454T2 (de) 2008-06-26
EP1539115B1 (en) 2007-09-19
IL166489A (en) 2014-01-30
CA2494234A1 (en) 2004-02-05
PL376258A1 (en) 2005-12-27
CN1684670A (zh) 2005-10-19
TWI363637B (en) 2012-05-11
JP2005535682A (ja) 2005-11-24
ATE373472T1 (de) 2007-10-15
RU2321391C2 (ru) 2008-04-10
NO324821B1 (no) 2007-12-10
TW200418524A (en) 2004-10-01

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