BR0313139A - Métodos e formas de dosagem para fornecimento controlado de paliperidona - Google Patents

Métodos e formas de dosagem para fornecimento controlado de paliperidona

Info

Publication number
BR0313139A
BR0313139A BR0313139-4A BR0313139A BR0313139A BR 0313139 A BR0313139 A BR 0313139A BR 0313139 A BR0313139 A BR 0313139A BR 0313139 A BR0313139 A BR 0313139A
Authority
BR
Brazil
Prior art keywords
paliperidone
methods
dosage forms
peak plasma
release
Prior art date
Application number
BR0313139-4A
Other languages
English (en)
Inventor
Noymi V Yam
Iran Reyes
Nipun Davar
Atul D Ayer
Julie Lee
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31191280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0313139(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of BR0313139A publication Critical patent/BR0313139A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"MéTODOS E FORMAS DE DOSAGEM PARA FORNECIMENTO CONTROLADO DE PALIPERIDONA". A presente invenção refere-se a formas de dosagem e métodos para prover uma taxa substancialmente ascendente de liberação de paliperidona. As formas de dosagem de liberação sustentada provêem concentrações de paliperidona no plasma de estado constante média terapeuticamente eficaz quando administradas uma vez por dia. Este regime de administração dosada uma vez por dia resulta em apenas uma ocorrência de concentração de paliperidona no plasma de pico em cada período de 24 horas. Além disso, a concentração de paliperidona no plasma de pico ocorre em um tempo mais tarde após a administração de dose e exibe uma magnitude mais baixa do que a concentração de paliperidona no plasma de pico que ocorre após a administração de paliperidona em uma forma de dosagem de liberação imediata.
BR0313139-4A 2002-07-29 2003-07-28 Métodos e formas de dosagem para fornecimento controlado de paliperidona BR0313139A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39959002P 2002-07-29 2002-07-29
US40600502P 2002-08-26 2002-08-26
PCT/US2003/023433 WO2004010981A1 (en) 2002-07-29 2003-07-28 Methods and dosage forms for controlled delivery of paliperidone

Publications (1)

Publication Number Publication Date
BR0313139A true BR0313139A (pt) 2005-07-05

Family

ID=31191280

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313139-4A BR0313139A (pt) 2002-07-29 2003-07-28 Métodos e formas de dosagem para fornecimento controlado de paliperidona

Country Status (29)

Country Link
US (1) US20040092534A1 (pt)
EP (1) EP1539115B1 (pt)
JP (1) JP4500679B2 (pt)
KR (1) KR100699516B1 (pt)
CN (1) CN1684670A (pt)
AR (1) AR040721A1 (pt)
AT (1) ATE373472T1 (pt)
AU (1) AU2003256844A1 (pt)
BR (1) BR0313139A (pt)
CA (1) CA2494234C (pt)
CO (1) CO5580742A2 (pt)
CY (1) CY1107096T1 (pt)
DE (1) DE60316454T2 (pt)
DK (1) DK1539115T3 (pt)
ES (1) ES2293039T3 (pt)
HK (1) HK1072559A1 (pt)
HR (1) HRP20050077B1 (pt)
IL (1) IL166489A (pt)
MX (1) MXPA05001191A (pt)
MY (1) MY137049A (pt)
NO (1) NO324821B1 (pt)
NZ (1) NZ570198A (pt)
PE (1) PE20040132A1 (pt)
PL (1) PL210119B1 (pt)
PT (1) PT1539115E (pt)
RU (1) RU2321391C2 (pt)
TW (1) TWI363637B (pt)
WO (1) WO2004010981A1 (pt)
ZA (1) ZA200501641B (pt)

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Also Published As

Publication number Publication date
NO324821B1 (no) 2007-12-10
DK1539115T3 (da) 2008-01-28
US20040092534A1 (en) 2004-05-13
JP4500679B2 (ja) 2010-07-14
MY137049A (en) 2008-12-31
TWI363637B (en) 2012-05-11
IL166489A0 (en) 2006-01-15
IL166489A (en) 2014-01-30
TW200418524A (en) 2004-10-01
EP1539115A1 (en) 2005-06-15
ES2293039T3 (es) 2008-03-16
KR100699516B1 (ko) 2007-03-26
ATE373472T1 (de) 2007-10-15
PL210119B1 (pl) 2011-12-30
AU2003256844A1 (en) 2004-02-16
PL376258A1 (en) 2005-12-27
JP2005535682A (ja) 2005-11-24
ZA200501641B (en) 2005-08-31
DE60316454T2 (de) 2008-06-26
CY1107096T1 (el) 2012-10-24
CO5580742A2 (es) 2005-11-30
RU2321391C2 (ru) 2008-04-10
NZ570198A (en) 2010-01-29
CN1684670A (zh) 2005-10-19
HRP20050077A2 (en) 2005-12-31
HRP20050077B1 (hr) 2013-11-22
AR040721A1 (es) 2005-04-20
WO2004010981A1 (en) 2004-02-05
NO20050956L (no) 2005-04-27
DE60316454D1 (de) 2007-10-31
CA2494234C (en) 2009-10-27
HK1072559A1 (en) 2005-09-02
CA2494234A1 (en) 2004-02-05
PT1539115E (pt) 2008-01-14
KR20050044895A (ko) 2005-05-13
MXPA05001191A (es) 2005-09-12
RU2005102105A (ru) 2005-08-10
EP1539115B1 (en) 2007-09-19
PE20040132A1 (es) 2004-03-06

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