BR0309620A - Métodos e formas de dosagem para liberação controlada de oxicodona - Google Patents
Métodos e formas de dosagem para liberação controlada de oxicodonaInfo
- Publication number
- BR0309620A BR0309620A BR0309620-3A BR0309620A BR0309620A BR 0309620 A BR0309620 A BR 0309620A BR 0309620 A BR0309620 A BR 0309620A BR 0309620 A BR0309620 A BR 0309620A
- Authority
- BR
- Brazil
- Prior art keywords
- oxycodone
- methods
- dosage forms
- release
- controlled release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Abstract
"MéTODOS E FORMAS DE DOSAGEM PARA LIBERAçãO CONTROLADA DE OXICODONA". Formas de dosagem e métodos para a liberação controlada de oxicodona durante um período de tempo prolongado são descritos. As formas de dosagem de liberação prolongada provêem concentrações de oxicodona no plasma de estado estável médio terapeuticamente eficazes quando administradas uma vez por dia. Este regime de dose de uma vez por dia resulta apenas na ocorrência de uma concentração de pico de oxicodona no plasma em cada período de 24 horas que acontece mais tarde após administração e exibe uma magnitude menor do que a concentração de pico de oxicodona no plasma que acontece seguindo administração de oxicodona em uma forma de liberação imediata e outras formas de dosagem de liberação prolongada da técnica anterior.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37647002P | 2002-04-29 | 2002-04-29 | |
PCT/US2003/012781 WO2003092648A1 (en) | 2002-04-29 | 2003-04-25 | Methods and dosage forms for controlled delivery of oxycodone |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0309620A true BR0309620A (pt) | 2005-03-15 |
Family
ID=29401352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0309620-3A BR0309620A (pt) | 2002-04-29 | 2003-04-25 | Métodos e formas de dosagem para liberação controlada de oxicodona |
Country Status (24)
Country | Link |
---|---|
US (1) | US20040010000A1 (pt) |
EP (1) | EP1499291B1 (pt) |
JP (1) | JP2005525405A (pt) |
CN (1) | CN1665482A (pt) |
AR (1) | AR039491A1 (pt) |
AT (1) | ATE419830T1 (pt) |
AU (1) | AU2003234216A1 (pt) |
BR (1) | BR0309620A (pt) |
CA (1) | CA2483655A1 (pt) |
DE (1) | DE60325715D1 (pt) |
EC (1) | ECSP045451A (pt) |
ES (1) | ES2320435T3 (pt) |
HK (1) | HK1072558A1 (pt) |
IL (1) | IL164911A0 (pt) |
MX (1) | MXPA04010769A (pt) |
NO (1) | NO20045117L (pt) |
NZ (1) | NZ536252A (pt) |
PE (1) | PE20031017A1 (pt) |
PL (1) | PL373031A1 (pt) |
RU (1) | RU2004134594A (pt) |
TW (1) | TW200404010A (pt) |
UY (1) | UY27789A1 (pt) |
WO (1) | WO2003092648A1 (pt) |
ZA (1) | ZA200409549B (pt) |
Families Citing this family (67)
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UA81224C2 (uk) * | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
EP2957281A1 (en) | 2001-09-21 | 2015-12-23 | Egalet Ltd. | Polymer release system |
WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
US20050106249A1 (en) * | 2002-04-29 | 2005-05-19 | Stephen Hwang | Once-a-day, oral, controlled-release, oxycodone dosage forms |
IL165361A0 (en) * | 2002-05-31 | 2006-01-15 | Alza Corp | Dosage forms and compositions for osmotic deliveryof variable dosages of oxycodone |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE602004031096D1 (de) | 2003-03-26 | 2011-03-03 | Egalet As | Morphin-system mit kontrollierter freisetzung |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102005005446A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE102004020220A1 (de) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE10336400A1 (de) * | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102004032051A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
CN1933837A (zh) * | 2003-10-29 | 2007-03-21 | 阿尔扎公司 | 一天一次经口受控释放氧可酮剂型 |
TWI483944B (zh) | 2004-03-30 | 2015-05-11 | Euro Celtique Sa | 含有小於25ppm14-羥可待因酮之羥可酮鹽酸鹽組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝 |
WO2005123039A1 (en) | 2004-06-12 | 2005-12-29 | Collegium Pharmaceutical, Inc. | Abuse-deterrent drug formulations |
DE102004032103A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102004032049A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
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DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
PL116330U1 (en) * | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
US7581776B2 (en) * | 2005-11-23 | 2009-09-01 | Wilhelm Karmann Gmbh | Convertible top having over center linkage |
SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
CA2687192C (en) | 2007-06-04 | 2015-11-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
US20090030072A1 (en) * | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
NZ586792A (en) | 2008-01-25 | 2012-09-28 | Gruenenthal Chemie | Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces |
US9226907B2 (en) | 2008-02-01 | 2016-01-05 | Abbvie Inc. | Extended release hydrocodone acetaminophen and related methods and uses thereof |
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US20110020451A1 (en) | 2009-07-22 | 2011-01-27 | Grunenthal Gmbh | Tamper-resistant dosage form for oxidation-sensitive opioids |
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US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
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BR112012022363A2 (pt) | 2010-03-04 | 2016-07-05 | Wockhardt Ltd | forma de dosagem com liberação modificada |
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SI2838512T1 (sl) | 2012-04-18 | 2018-11-30 | Gruenenthal Gmbh | Pred posegi in prehitrim sproščanjem odporna farmacevtska oblika odmerka |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
BR112015000150A2 (pt) | 2012-07-06 | 2017-06-27 | Egalet Ltd | composições farmacêuticas dissuasoras de abuso de liberação controlada |
US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
WO2014191396A1 (en) | 2013-05-29 | 2014-12-04 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
BR112015026549A2 (pt) | 2013-05-29 | 2017-07-25 | Gruenenthal Gmbh | forma de dosagem à prova de violação contendo uma ou mais partículas |
CN105682643B (zh) | 2013-07-12 | 2019-12-13 | 格吕伦塔尔有限公司 | 含有乙烯-醋酸乙烯酯聚合物的防篡改剂型 |
WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
MX371372B (es) | 2013-11-26 | 2020-01-28 | Gruenenthal Gmbh | Preparacion de una composicion farmaceutica en polvo por medio de criomolienda. |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
AU2015261060A1 (en) | 2014-05-12 | 2016-11-03 | Grunenthal Gmbh | Tamper resistant immediate release capsule formulation comprising Tapentadol |
US9872835B2 (en) | 2014-05-26 | 2018-01-23 | Grünenthal GmbH | Multiparticles safeguarded against ethanolic dose-dumping |
DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
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-
2003
- 2003-04-25 BR BR0309620-3A patent/BR0309620A/pt not_active IP Right Cessation
- 2003-04-25 CA CA002483655A patent/CA2483655A1/en not_active Abandoned
- 2003-04-25 EP EP03728526A patent/EP1499291B1/en not_active Expired - Lifetime
- 2003-04-25 CN CN038154773A patent/CN1665482A/zh active Pending
- 2003-04-25 DE DE60325715T patent/DE60325715D1/de not_active Expired - Lifetime
- 2003-04-25 US US10/423,454 patent/US20040010000A1/en not_active Abandoned
- 2003-04-25 AT AT03728526T patent/ATE419830T1/de not_active IP Right Cessation
- 2003-04-25 AU AU2003234216A patent/AU2003234216A1/en not_active Abandoned
- 2003-04-25 RU RU2004134594/15A patent/RU2004134594A/ru not_active Application Discontinuation
- 2003-04-25 ES ES03728526T patent/ES2320435T3/es not_active Expired - Lifetime
- 2003-04-25 PL PL03373031A patent/PL373031A1/xx not_active Application Discontinuation
- 2003-04-25 MX MXPA04010769A patent/MXPA04010769A/es unknown
- 2003-04-25 JP JP2004500833A patent/JP2005525405A/ja not_active Withdrawn
- 2003-04-25 NZ NZ536252A patent/NZ536252A/en unknown
- 2003-04-25 WO PCT/US2003/012781 patent/WO2003092648A1/en active Application Filing
- 2003-04-28 TW TW092109908A patent/TW200404010A/zh unknown
- 2003-04-29 AR ARP030101492A patent/AR039491A1/es not_active Application Discontinuation
- 2003-04-29 UY UY27789A patent/UY27789A1/es not_active Application Discontinuation
- 2003-04-29 PE PE2003000425A patent/PE20031017A1/es not_active Application Discontinuation
-
2004
- 2004-10-28 IL IL16491104A patent/IL164911A0/xx unknown
- 2004-11-24 NO NO20045117A patent/NO20045117L/no not_active Application Discontinuation
- 2004-11-24 EC EC2004005451A patent/ECSP045451A/es unknown
- 2004-11-25 ZA ZA200409549A patent/ZA200409549B/en unknown
-
2005
- 2005-06-28 HK HK05105361.5A patent/HK1072558A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TW200404010A (en) | 2004-03-16 |
ATE419830T1 (de) | 2009-01-15 |
ECSP045451A (es) | 2005-01-28 |
CA2483655A1 (en) | 2003-11-13 |
ZA200409549B (en) | 2006-07-26 |
HK1072558A1 (en) | 2005-09-02 |
PE20031017A1 (es) | 2003-11-29 |
RU2004134594A (ru) | 2005-06-27 |
EP1499291A1 (en) | 2005-01-26 |
UY27789A1 (es) | 2003-08-29 |
CN1665482A (zh) | 2005-09-07 |
IL164911A0 (en) | 2005-12-18 |
NZ536252A (en) | 2007-06-29 |
NO20045117L (no) | 2005-01-14 |
US20040010000A1 (en) | 2004-01-15 |
AR039491A1 (es) | 2005-02-23 |
PL373031A1 (en) | 2005-08-08 |
WO2003092648A1 (en) | 2003-11-13 |
ES2320435T3 (es) | 2009-05-22 |
JP2005525405A (ja) | 2005-08-25 |
EP1499291B1 (en) | 2009-01-07 |
MXPA04010769A (es) | 2005-07-05 |
AU2003234216A1 (en) | 2003-11-17 |
DE60325715D1 (de) | 2009-02-26 |
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