CO6140021A2 - Composicion farmaceutica de liberacion modificada de un musculo relajante y un aine - Google Patents
Composicion farmaceutica de liberacion modificada de un musculo relajante y un aineInfo
- Publication number
- CO6140021A2 CO6140021A2 CO09050487A CO09050487A CO6140021A2 CO 6140021 A2 CO6140021 A2 CO 6140021A2 CO 09050487 A CO09050487 A CO 09050487A CO 09050487 A CO09050487 A CO 09050487A CO 6140021 A2 CO6140021 A2 CO 6140021A2
- Authority
- CO
- Colombia
- Prior art keywords
- pharmaceutical composition
- drug
- nsaid
- muscle relaxant
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
Abstract
1.- Una composición farmacéutica caracterizada porque las microesferas recubiertas comprenden: a) núcleos inertes recubiertos con una primera película formada por un fármaco músculo relajante, al menos un polímero adhesivo y al menos un agente plastificante; b) una segunda película polimérica retardante, al menos un agente plastificante y solución reguladora; y c) una tercera película formada por un fármaco AINE, el fármaco músculo relajante de la primera película, al menos un polímero adhesivo, al menos un agente plastificante y al menos un agente tensoactivo; en donde el fármaco músculo relajante presenta liberación modificada y el fármaco AINE presenta liberación inmediata. 2.- La composición farmacéutica de la reivindicación 1, en donde el fármaco músculo relajante presenta tiempos de concentración plasmática y de vida media diferente al tiempo de concentración plasmática y de vida media del fármaco AINE. 3.- La composición farmacéutica de la reivindicación 1, en donde el fármaco músculo relajante es tizanidina o sus sales farmacéuticamente aceptables. 4.- La composición farmacéutica de la reivindicación 1, en donde el fármaco AINE es meloxicam o sus sales farmacéuticamente aceptables. 5.- La composición farmacéutica de la reivindicación 3, en donde la concentración de tizanidina o sus sales farmacéuticamente aceptables es de 0.5 a 36% por cada unidad de dosis. 6.- La composición farmacéutica de la reivindicación 4, en donde la concentración de meloxicam o sus sales farmacéuticamente aceptables es de 2.0 a 15% por cada unidad de dosis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXPA06012024 | 2006-10-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6140021A2 true CO6140021A2 (es) | 2010-03-19 |
Family
ID=39313650
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO09050487A CO6140021A2 (es) | 2006-10-18 | 2009-05-18 | Composicion farmaceutica de liberacion modificada de un musculo relajante y un aine |
Country Status (16)
Country | Link |
---|---|
US (1) | US20100166856A1 (es) |
EP (1) | EP2085076B1 (es) |
AR (1) | AR073435A1 (es) |
AT (1) | ATE499089T1 (es) |
BR (1) | BRPI0718368A2 (es) |
CA (1) | CA2670690C (es) |
CL (1) | CL2007002975A1 (es) |
CO (1) | CO6140021A2 (es) |
CR (1) | CR10801A (es) |
DE (1) | DE602007012751D1 (es) |
EC (1) | ECSP099348A (es) |
ES (1) | ES2361883T3 (es) |
GT (1) | GT200900089A (es) |
PE (1) | PE20081464A1 (es) |
UY (1) | UY30636A1 (es) |
WO (1) | WO2008047208A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2009332963B2 (en) | 2008-12-31 | 2015-02-05 | Upsher-Smith Laboratories, Llc | Opioid-containing oral pharmaceutical compositions and methods |
WO2011034554A1 (en) * | 2009-09-17 | 2011-03-24 | Upsher-Smith Laboratories, Inc. | A sustained-release product comprising a combination of a non-opioid amine and a non-steroidal anti -inflammatory drug |
PL2338473T3 (pl) | 2009-12-18 | 2017-07-31 | Mdm S.P.A. | Postacie farmaceutycznej dawki tizanidyny i drogi jej podawania |
BRPI1103205A2 (pt) * | 2011-06-03 | 2014-02-25 | Eurofarma Lab Ltda | Composição farmacêutica oral e uso da composição farmacêutica oral |
EP2841072A4 (en) * | 2012-04-27 | 2016-01-06 | Troy Lab Pty Ltd | POLYTHERAPY FOR ANIMALS BASED ON MELOXICAM AND XYLAZINE |
US20170189374A1 (en) * | 2014-07-21 | 2017-07-06 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Zaltoprofen and muscle relaxant combinations |
WO2016193880A1 (en) * | 2015-05-29 | 2016-12-08 | Jubilant Generics Limited | Immediate release pharmaceutical composition of tizanidine |
US20190060287A1 (en) * | 2017-08-28 | 2019-02-28 | Adare Pharmaceuticals, Inc. | Tizanidine formulations |
CN113398096A (zh) * | 2021-06-27 | 2021-09-17 | 烟台大学 | 一种含有美洛昔康的长效注射微球及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2735369B1 (fr) * | 1995-06-13 | 1997-07-11 | Synthelabo | Compositions pharmaceutiques a base de sel de sodium du diclofenac et de thiocolchicoside |
KR100210509B1 (ko) * | 1996-01-10 | 1999-07-15 | 성재갑 | 지속성 동물 성장 호르몬 제형 및 이의 제조 방법 |
US5766623A (en) * | 1996-03-25 | 1998-06-16 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University | Compactable self-sealing drug delivery agents |
US20040204413A1 (en) * | 2001-01-26 | 2004-10-14 | Joaquina Faour | Pharmaceutical compositions containing a COX-II inhibitor and a muscle relaxant |
ATE380022T1 (de) * | 2001-01-31 | 2007-12-15 | Evonik Roehm Gmbh | Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen |
US20050100594A1 (en) * | 2003-11-12 | 2005-05-12 | Nilendu Sen | Pharmaceutical formulation containing muscle relaxant and COX-II inhibitor |
US8502335B2 (en) | 2009-07-29 | 2013-08-06 | Taiwan Semiconductor Manufacturing Company, Ltd. | CMOS image sensor big via bonding pad application for AlCu Process |
-
2007
- 2007-10-09 UY UY30636A patent/UY30636A1/es not_active Application Discontinuation
- 2007-10-09 AR ARP070104457A patent/AR073435A1/es not_active Application Discontinuation
- 2007-10-16 WO PCT/IB2007/003083 patent/WO2008047208A1/es active Application Filing
- 2007-10-16 CA CA2670690A patent/CA2670690C/en not_active Expired - Fee Related
- 2007-10-16 BR BRPI0718368-2A patent/BRPI0718368A2/pt active Search and Examination
- 2007-10-16 AT AT07825384T patent/ATE499089T1/de not_active IP Right Cessation
- 2007-10-16 ES ES07825384T patent/ES2361883T3/es active Active
- 2007-10-16 EP EP07825384A patent/EP2085076B1/en not_active Not-in-force
- 2007-10-16 US US12/446,293 patent/US20100166856A1/en not_active Abandoned
- 2007-10-16 DE DE602007012751T patent/DE602007012751D1/de active Active
- 2007-10-17 CL CL2007002975A patent/CL2007002975A1/es unknown
- 2007-10-18 PE PE2007001409A patent/PE20081464A1/es active IP Right Grant
-
2009
- 2009-04-17 GT GT200900089A patent/GT200900089A/es unknown
- 2009-05-18 CR CR10801A patent/CR10801A/es unknown
- 2009-05-18 CO CO09050487A patent/CO6140021A2/es unknown
- 2009-05-19 EC EC2009009348A patent/ECSP099348A/es unknown
Also Published As
Publication number | Publication date |
---|---|
CR10801A (es) | 2009-07-03 |
AR073435A1 (es) | 2010-11-10 |
CL2007002975A1 (es) | 2008-01-04 |
EP2085076A1 (en) | 2009-08-05 |
ATE499089T1 (de) | 2011-03-15 |
EP2085076A4 (en) | 2010-03-17 |
ES2361883T3 (es) | 2011-06-24 |
GT200900089A (es) | 2012-01-13 |
CA2670690C (en) | 2014-12-30 |
US20100166856A1 (en) | 2010-07-01 |
PE20081464A1 (es) | 2008-12-31 |
EP2085076B1 (en) | 2011-02-23 |
UY30636A1 (es) | 2008-05-02 |
WO2008047208A1 (es) | 2008-04-24 |
BRPI0718368A2 (pt) | 2013-11-12 |
CA2670690A1 (en) | 2008-04-24 |
ECSP099348A (es) | 2009-06-30 |
DE602007012751D1 (de) | 2011-04-07 |
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