GT200900089A - Composicion farmaceutica en forma de microesferas recubiertas para la liberacion modificada de un relajante muscular y un aine - Google Patents
Composicion farmaceutica en forma de microesferas recubiertas para la liberacion modificada de un relajante muscular y un aineInfo
- Publication number
- GT200900089A GT200900089A GT200900089A GT200900089A GT200900089A GT 200900089 A GT200900089 A GT 200900089A GT 200900089 A GT200900089 A GT 200900089A GT 200900089 A GT200900089 A GT 200900089A GT 200900089 A GT200900089 A GT 200900089A
- Authority
- GT
- Guatemala
- Prior art keywords
- pharmaceutical composition
- modified release
- nsaid
- muscle relaxant
- coated microspheres
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A UNA COMPOSICIÓN FARMACÉUTICA DE LIBERACIÓN MODIFICADA EN CÁPSULAS CON MICROESFERAS RECUBIERTAS QUE COMPRENDE LA COMBINACIÓN DE DOS PRINCIPIOS ACTIVOS DE TIEMPOS DE CONCENTRACIÓN PLASMÁTICA RADICALMENTE DIFERENTES, ÉSTOS SON UN MÚSCULO RELAJANTE (TIZANIDINA) Y UN ANALGÉSICO ANTIINFLAMATORIO NO ESTEROIDE (MELOXICAM), VEHÍCULOS O EXCIPIENTES FARMACÉUTICAMENTE ACEPTABLES; ASÍ COMO A UN PROCESO PARA LA MANUFACTURA DE LA COMPOSICIÓN Y AL USO DE DICHA COMBINACIÓN PARA LA PREPARACIÓN DE UN MEDICAMENTO CON ACTIVIDAD TERAPÉUTICA SINÉRGICA INDICADA EN EL TRATAMIENTO DE ESPASTICIDAD, DESÓRDENES RELACIONADOS CON PADECIMIENTOS MUSCULARES Y/O MÚSCULO ESQUELÉTICO Y DOLOR EN GENERAL DE MODERADO A SEVERO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXPA06012024 | 2006-10-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200900089A true GT200900089A (es) | 2012-01-13 |
Family
ID=39313650
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200900089A GT200900089A (es) | 2006-10-18 | 2009-04-17 | Composicion farmaceutica en forma de microesferas recubiertas para la liberacion modificada de un relajante muscular y un aine |
Country Status (16)
Country | Link |
---|---|
US (1) | US20100166856A1 (es) |
EP (1) | EP2085076B1 (es) |
AR (1) | AR073435A1 (es) |
AT (1) | ATE499089T1 (es) |
BR (1) | BRPI0718368A2 (es) |
CA (1) | CA2670690C (es) |
CL (1) | CL2007002975A1 (es) |
CO (1) | CO6140021A2 (es) |
CR (1) | CR10801A (es) |
DE (1) | DE602007012751D1 (es) |
EC (1) | ECSP099348A (es) |
ES (1) | ES2361883T3 (es) |
GT (1) | GT200900089A (es) |
PE (1) | PE20081464A1 (es) |
UY (1) | UY30636A1 (es) |
WO (1) | WO2008047208A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010078486A2 (en) | 2008-12-31 | 2010-07-08 | Upsher-Smith Laboratories, Inc. | Opioid-containing oral pharmaceutical compositions and methods |
BR112012008317A2 (pt) * | 2009-09-17 | 2016-03-22 | Upsher Smith Lab Inc | produto de liberação sustentada compreendendo uma combinação de uma amina não-opioide e uma droga anti-inflamatória não-esteroidal |
PL2338473T3 (pl) | 2009-12-18 | 2017-07-31 | Mdm S.P.A. | Postacie farmaceutycznej dawki tizanidyny i drogi jej podawania |
BRPI1103205A2 (pt) * | 2011-06-03 | 2014-02-25 | Eurofarma Lab Ltda | Composição farmacêutica oral e uso da composição farmacêutica oral |
NZ701190A (en) * | 2012-04-27 | 2016-07-29 | Troy Lab Pty Ltd | Combination meloxicam and xylazine therapy in animals |
EP2977045A1 (en) * | 2014-07-21 | 2016-01-27 | Sanovel Ilac Sanayi ve Ticaret A.S. | Zaltoprofen and muscle relaxant combinations |
US10813916B2 (en) * | 2015-05-29 | 2020-10-27 | Jubilant Generics Limited | Immediate release pharmaceutical composition of tizanidine |
US20190060287A1 (en) * | 2017-08-28 | 2019-02-28 | Adare Pharmaceuticals, Inc. | Tizanidine formulations |
CN113398096A (zh) * | 2021-06-27 | 2021-09-17 | 烟台大学 | 一种含有美洛昔康的长效注射微球及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2735369B1 (fr) * | 1995-06-13 | 1997-07-11 | Synthelabo | Compositions pharmaceutiques a base de sel de sodium du diclofenac et de thiocolchicoside |
KR100210509B1 (ko) * | 1996-01-10 | 1999-07-15 | 성재갑 | 지속성 동물 성장 호르몬 제형 및 이의 제조 방법 |
US5766623A (en) * | 1996-03-25 | 1998-06-16 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University | Compactable self-sealing drug delivery agents |
US20040204413A1 (en) * | 2001-01-26 | 2004-10-14 | Joaquina Faour | Pharmaceutical compositions containing a COX-II inhibitor and a muscle relaxant |
KR100507946B1 (ko) * | 2001-01-31 | 2005-08-17 | 룀 게엠베하 운트 콤파니 카게 | 상이하게 피복된 펠렛 형태를 두 가지 이상 포함하는 다중 입상형 약제 |
US20050100594A1 (en) * | 2003-11-12 | 2005-05-12 | Nilendu Sen | Pharmaceutical formulation containing muscle relaxant and COX-II inhibitor |
US8502335B2 (en) | 2009-07-29 | 2013-08-06 | Taiwan Semiconductor Manufacturing Company, Ltd. | CMOS image sensor big via bonding pad application for AlCu Process |
-
2007
- 2007-10-09 AR ARP070104457A patent/AR073435A1/es not_active Application Discontinuation
- 2007-10-09 UY UY30636A patent/UY30636A1/es not_active Application Discontinuation
- 2007-10-16 CA CA2670690A patent/CA2670690C/en not_active Expired - Fee Related
- 2007-10-16 ES ES07825384T patent/ES2361883T3/es active Active
- 2007-10-16 DE DE602007012751T patent/DE602007012751D1/de active Active
- 2007-10-16 US US12/446,293 patent/US20100166856A1/en not_active Abandoned
- 2007-10-16 AT AT07825384T patent/ATE499089T1/de not_active IP Right Cessation
- 2007-10-16 BR BRPI0718368-2A patent/BRPI0718368A2/pt active Search and Examination
- 2007-10-16 EP EP07825384A patent/EP2085076B1/en not_active Not-in-force
- 2007-10-16 WO PCT/IB2007/003083 patent/WO2008047208A1/es active Application Filing
- 2007-10-17 CL CL2007002975A patent/CL2007002975A1/es unknown
- 2007-10-18 PE PE2007001409A patent/PE20081464A1/es active IP Right Grant
-
2009
- 2009-04-17 GT GT200900089A patent/GT200900089A/es unknown
- 2009-05-18 CR CR10801A patent/CR10801A/es unknown
- 2009-05-18 CO CO09050487A patent/CO6140021A2/es unknown
- 2009-05-19 EC EC2009009348A patent/ECSP099348A/es unknown
Also Published As
Publication number | Publication date |
---|---|
CL2007002975A1 (es) | 2008-01-04 |
EP2085076A4 (en) | 2010-03-17 |
EP2085076B1 (en) | 2011-02-23 |
CO6140021A2 (es) | 2010-03-19 |
ECSP099348A (es) | 2009-06-30 |
UY30636A1 (es) | 2008-05-02 |
DE602007012751D1 (de) | 2011-04-07 |
ES2361883T3 (es) | 2011-06-24 |
CR10801A (es) | 2009-07-03 |
US20100166856A1 (en) | 2010-07-01 |
PE20081464A1 (es) | 2008-12-31 |
CA2670690C (en) | 2014-12-30 |
ATE499089T1 (de) | 2011-03-15 |
EP2085076A1 (en) | 2009-08-05 |
WO2008047208A1 (es) | 2008-04-24 |
CA2670690A1 (en) | 2008-04-24 |
AR073435A1 (es) | 2010-11-10 |
BRPI0718368A2 (pt) | 2013-11-12 |
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