HK1072559A1 - Methods and dosage forms for controled delivery ofpaliperidone - Google Patents
Methods and dosage forms for controled delivery ofpaliperidoneInfo
- Publication number
- HK1072559A1 HK1072559A1 HK05105362A HK05105362A HK1072559A1 HK 1072559 A1 HK1072559 A1 HK 1072559A1 HK 05105362 A HK05105362 A HK 05105362A HK 05105362 A HK05105362 A HK 05105362A HK 1072559 A1 HK1072559 A1 HK 1072559A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- ofpaliperidone
- controled
- delivery
- methods
- dosage forms
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39959002P | 2002-07-29 | 2002-07-29 | |
US40600502P | 2002-08-26 | 2002-08-26 | |
PCT/US2003/023433 WO2004010981A1 (en) | 2002-07-29 | 2003-07-28 | Methods and dosage forms for controlled delivery of paliperidone |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1072559A1 true HK1072559A1 (en) | 2005-09-02 |
Family
ID=31191280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05105362A HK1072559A1 (en) | 2002-07-29 | 2005-06-28 | Methods and dosage forms for controled delivery ofpaliperidone |
Country Status (29)
Country | Link |
---|---|
US (1) | US20040092534A1 (xx) |
EP (1) | EP1539115B1 (xx) |
JP (1) | JP4500679B2 (xx) |
KR (1) | KR100699516B1 (xx) |
CN (1) | CN1684670A (xx) |
AR (1) | AR040721A1 (xx) |
AT (1) | ATE373472T1 (xx) |
AU (1) | AU2003256844A1 (xx) |
BR (1) | BR0313139A (xx) |
CA (1) | CA2494234C (xx) |
CO (1) | CO5580742A2 (xx) |
CY (1) | CY1107096T1 (xx) |
DE (1) | DE60316454T2 (xx) |
DK (1) | DK1539115T3 (xx) |
ES (1) | ES2293039T3 (xx) |
HK (1) | HK1072559A1 (xx) |
HR (1) | HRP20050077B1 (xx) |
IL (1) | IL166489A (xx) |
MX (1) | MXPA05001191A (xx) |
MY (1) | MY137049A (xx) |
NO (1) | NO324821B1 (xx) |
NZ (1) | NZ570198A (xx) |
PE (1) | PE20040132A1 (xx) |
PL (1) | PL210119B1 (xx) |
PT (1) | PT1539115E (xx) |
RU (1) | RU2321391C2 (xx) |
TW (1) | TWI363637B (xx) |
WO (1) | WO2004010981A1 (xx) |
ZA (1) | ZA200501641B (xx) |
Families Citing this family (66)
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US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
DE602005008460D1 (de) * | 2004-08-04 | 2008-09-04 | Alza Corp | Zusammensetzung mit verzögerter arzneimittelfreisetzung mit einem aufsteigenden nullordnung-freigabe-muster; verfahren zur herstellung einer solchen zusammensetzung" |
WO2006085856A1 (en) * | 2005-02-04 | 2006-08-17 | Alza Corporation | Methods and dosage forms for reducing side effects of benzisozazole derivatives |
US20060189635A1 (en) * | 2005-02-04 | 2006-08-24 | Michelle Kramer | Enhanced efficacy benzisoxazole derivative dosage forms and methods |
EP1912622A2 (en) * | 2005-08-04 | 2008-04-23 | Alza Corporation | Osmotic dosage forms comprising semipermeable membranes with polymer blends providing improved properties |
US20070166381A1 (en) * | 2006-01-06 | 2007-07-19 | Iran Reyes | Osmotic dosage form with controlled release and fast release aspects |
SI3095447T1 (sl) | 2006-02-03 | 2022-02-28 | Opko Renal, Llc | Zdravljenje pomanjkanja vitamina D s 25-hidroksivitaminom D2 in 25-hidroksivitaminom D3 |
US20070232624A1 (en) | 2006-04-03 | 2007-10-04 | Palumbo Joseph M | Use of paliperidone for the treatment of sleep disturbances and/or excessive daytime sleepiness in psychiatric patients |
PT2679228T (pt) | 2006-06-21 | 2018-04-16 | Opko Ireland Global Holdings Ltd | Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d |
US8524749B2 (en) * | 2007-02-09 | 2013-09-03 | Alza Corporation | Controlled release compositions of tizanidine |
PL2148684T3 (pl) | 2007-04-25 | 2013-06-28 | Cytochroma Inc | Sposób leczenia niedoboru i deficytu witaminy D |
PT2148661E (pt) | 2007-04-25 | 2013-03-06 | Proventiv Therapeutics Llc | Composições orais de libertação controlada compreendendo um composto de vitamina d e veículo ceroso |
PT2079446E (pt) * | 2007-08-21 | 2011-12-23 | Teva Pharma | Formulação de libertação sustida de paliperidona |
KR101041203B1 (ko) | 2007-09-25 | 2011-06-13 | 테바 파마슈티컬 인더스트리즈 리미티드 | 안정한 이매티닙 조성물 |
EP2234617B1 (en) | 2007-12-19 | 2021-03-31 | Janssen Pharmaceutica NV | Dosing regimen associated with long acting injectable paliperidone esters |
US20090247553A1 (en) * | 2008-03-27 | 2009-10-01 | Actavis Group Ptc Ehf | Highly Pure Paliperidone or a Pharmaceutically Acceptable Salt Thereof Substantially Free of Keto Impurity |
WO2010009900A1 (en) * | 2008-07-25 | 2010-01-28 | Krka, D.D. Novo Mesto | Paliperidone composition comprising solid matrix particles |
EP2161019A1 (en) | 2008-09-05 | 2010-03-10 | KRKA, D.D., Novo Mesto | Prolonged release multiparticulate pharmaceutical composition comprising paliperidone |
WO2010044097A2 (en) | 2008-09-15 | 2010-04-22 | Intas Pharmaceuticals Limited | Novel dosage form of paliperidone and process for preparing the same |
BRPI0919465A2 (pt) * | 2008-09-30 | 2015-12-01 | Endo Pharmaceuticals Solutions | dispositivo implantável para a liberação de risperidona e métodos de uso do mesmo |
WO2011018246A2 (en) | 2009-08-13 | 2011-02-17 | Synthon B.V. | Controlled release paliperidone composition |
US20110052687A1 (en) * | 2009-08-26 | 2011-03-03 | Glenmark Generics Ltd | Extended release pharmaceutical composition of paliperidone |
EP2488162A2 (en) * | 2009-10-16 | 2012-08-22 | Ranbaxy Laboratories Limited | Extended release pharmaceutical compositions of paliperidone and processes of preparation thereof |
EP2547206B1 (en) * | 2010-03-15 | 2016-05-11 | Inventia Healthcare Private Limited | Stabilized prolonged release pharmaceutical composition comprising atypical antipsychotic |
PT2552484T (pt) | 2010-03-29 | 2020-04-03 | Opko Ireland Global Holdings Ltd | Métodos e composições para redução dos níveis de parafróides |
ES2602503T3 (es) | 2010-04-22 | 2017-02-21 | Intra-Cellular Therapies, Inc. | Compuestos orgánicos |
US20120201886A1 (en) | 2010-07-30 | 2012-08-09 | Micro Labs Limited | Coated Extended Release Pharmaceutical Compositions Containing Paliperidone |
CN102058517A (zh) * | 2010-12-31 | 2011-05-18 | 泰州万全医药科技有限公司 | 一种帕潘立酮缓释剂及其制备方法 |
US20130034605A1 (en) | 2011-08-01 | 2013-02-07 | Micro Labs Limited | Extended release pharmaceutical compositions containing paliperidone |
CN102274164B (zh) * | 2011-08-22 | 2014-07-02 | 长春健欣生物医药科技开发有限公司 | 帕潘立酮及帕潘立酮衍生物的注射用缓释凝胶剂 |
IN2014DN08562A (xx) | 2012-04-14 | 2015-05-22 | Intra Cellular Therapies Inc | |
WO2014102741A2 (en) * | 2012-12-28 | 2014-07-03 | University Of The Witwatersrand, Johannesburg | Pharmaceutical dosage form |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
PT2968320T (pt) | 2013-03-15 | 2021-01-28 | Intra Cellular Therapies Inc | Compostos orgânicos |
CN103271889B (zh) * | 2013-05-23 | 2015-10-28 | 沈阳药科大学 | 帕利哌酮新型递增释放渗透泵制剂及其制备方法 |
CN103385857A (zh) * | 2013-06-29 | 2013-11-13 | 北京万全德众医药生物技术有限公司 | 帕利哌酮的药物组合物 |
WO2015001488A1 (en) | 2013-07-01 | 2015-01-08 | Ranbaxy Laboratories Limited | Extended-release tablets of paliperidone and processes of preparation thereof |
PL3076967T3 (pl) | 2013-12-03 | 2021-12-20 | Intra-Cellular Therapies, Inc. | Metody leczenia objawów rezydualnych schizofrenii |
US9745300B2 (en) | 2014-04-04 | 2017-08-29 | Intra-Cellular Therapies, Inc. | Organic compounds |
BR112016023162B1 (pt) | 2014-04-04 | 2022-11-29 | Intra-Cellular Therapies, Inc | Compostos orgânicos gama-carbolinas, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento ou na profilaxia de transtornos de sistema nervoso central |
US10179776B2 (en) | 2014-06-09 | 2019-01-15 | Intra-Cellular Therapies, Inc. | Compounds and methods of use to treat schizophrenia |
US20160000654A1 (en) * | 2014-07-07 | 2016-01-07 | Cadila Healthcare Limited | Method for determining formulation orientation of asymmetric multi-layered osmotic tablets |
EP3193925A2 (en) | 2014-08-07 | 2017-07-26 | OPKO Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin d |
CN104257622B (zh) * | 2014-10-01 | 2020-02-07 | 浙江华海药业股份有限公司 | 一种帕利哌酮控释片及其制备方法 |
US9844551B2 (en) | 2015-01-14 | 2017-12-19 | Children's Hospital Medical Center | Compositions and methods for treatment of fragile X syndrome |
GR1008842B (el) | 2015-08-06 | 2016-09-05 | Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων | Φαρμακευτικο σκευασμα περιεχον εναν ατυπο αντιψυχωσιμο παραγοντα και μεθοδος για την παρασκευη αυτου |
CN105147629B (zh) * | 2015-09-24 | 2017-08-25 | 吉林大学 | 一种异丁利酮片剂及制备方法 |
MX2018009158A (es) | 2016-01-26 | 2018-11-19 | Intra Cellular Therapies Inc | Compuestos organicos. |
PL3407889T3 (pl) | 2016-03-25 | 2021-11-22 | Intra-Cellular Therapies, Inc. | Związki organiczne i ich zastosowanie w leczeniu lub zapobieganiu zaburzeniom ośrodkowego układu nerwowego |
MX2018011820A (es) | 2016-03-28 | 2019-01-24 | Opko Ireland Global Holdings Ltd | Metodos de tratamiento con vitamina d. |
WO2017172795A1 (en) | 2016-03-28 | 2017-10-05 | Intra-Cellular Therapies, Inc. | Novel compositions and methods |
US20190105277A1 (en) | 2016-04-05 | 2019-04-11 | Pharmathen S.A. | Pharmaceutical composition comprising an atypical antipsychotic agent and method for the preparation thereof |
EP3525763A4 (en) | 2016-10-12 | 2020-06-17 | Intra-Cellular Therapies, Inc. | AMORPHE FIXED DISPERSIONS |
US20190321367A1 (en) * | 2016-11-23 | 2019-10-24 | Children's Hospital Medical Center | Paliperidone for treatment of drug refractory irritability and autism spectrum disorder |
CN106727392A (zh) * | 2016-12-15 | 2017-05-31 | 上海奕利制药有限公司 | 一种帕利哌酮缓释片剂及其制备方法 |
JP6987868B2 (ja) | 2016-12-29 | 2022-01-05 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
US10961245B2 (en) | 2016-12-29 | 2021-03-30 | Intra-Cellular Therapies, Inc. | Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders |
CN116327770A (zh) | 2017-03-24 | 2023-06-27 | 细胞内治疗公司 | 新组合物和方法 |
US11427587B2 (en) | 2017-07-26 | 2022-08-30 | Intra-Cellular Therapies, Inc. | Organic compounds |
CN111093665A (zh) | 2017-07-26 | 2020-05-01 | 细胞内治疗公司 | 有机化合物 |
CA3094949A1 (en) | 2018-03-23 | 2019-09-26 | Intra-Cellular Therapies, Inc. | Deuterated heterocycle fused gamma-carbolines |
BR112021003655A2 (pt) | 2018-08-31 | 2021-05-18 | Intra-Cellular Therapies, Inc. | métodos novos |
EP3843739A4 (en) | 2018-08-31 | 2022-06-01 | Intra-Cellular Therapies, Inc. | NEW METHODS |
KR102285510B1 (ko) | 2019-10-29 | 2021-08-04 | 강동국 | 양액 농도조절용 캡슐 및 그 용도 |
CN113616610B (zh) * | 2021-07-30 | 2023-05-12 | 石药集团欧意药业有限公司 | 一种帕利哌酮缓释片及其制备方法 |
US20230364009A1 (en) * | 2022-05-12 | 2023-11-16 | Celanese Eva Performance Polymers Llc | Implantable Medical Device for the Delivery of an Antipsychotic |
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-
2003
- 2003-07-28 MX MXPA05001191A patent/MXPA05001191A/es active IP Right Grant
- 2003-07-28 US US10/629,211 patent/US20040092534A1/en not_active Abandoned
- 2003-07-28 ES ES03771910T patent/ES2293039T3/es not_active Expired - Lifetime
- 2003-07-28 NZ NZ570198A patent/NZ570198A/en not_active IP Right Cessation
- 2003-07-28 AT AT03771910T patent/ATE373472T1/de active
- 2003-07-28 DE DE60316454T patent/DE60316454T2/de not_active Expired - Lifetime
- 2003-07-28 PL PL376258A patent/PL210119B1/pl unknown
- 2003-07-28 DK DK03771910T patent/DK1539115T3/da active
- 2003-07-28 AU AU2003256844A patent/AU2003256844A1/en not_active Abandoned
- 2003-07-28 KR KR1020057001460A patent/KR100699516B1/ko active IP Right Review Request
- 2003-07-28 PT PT03771910T patent/PT1539115E/pt unknown
- 2003-07-28 CN CNA03822948XA patent/CN1684670A/zh active Pending
- 2003-07-28 CA CA002494234A patent/CA2494234C/en not_active Expired - Lifetime
- 2003-07-28 BR BR0313139-4A patent/BR0313139A/pt not_active Application Discontinuation
- 2003-07-28 WO PCT/US2003/023433 patent/WO2004010981A1/en active IP Right Grant
- 2003-07-28 EP EP03771910A patent/EP1539115B1/en not_active Revoked
- 2003-07-28 RU RU2005102105/15A patent/RU2321391C2/ru not_active Application Discontinuation
- 2003-07-28 JP JP2004524886A patent/JP4500679B2/ja not_active Expired - Lifetime
- 2003-07-29 AR AR20030102717A patent/AR040721A1/es unknown
- 2003-07-29 MY MYPI20032846A patent/MY137049A/en unknown
- 2003-07-29 TW TW092120703A patent/TWI363637B/zh not_active IP Right Cessation
- 2003-07-30 PE PE2003000749A patent/PE20040132A1/es not_active Application Discontinuation
-
2005
- 2005-01-25 IL IL166489A patent/IL166489A/en active IP Right Grant
- 2005-01-25 HR HRP20050077AA patent/HRP20050077B1/hr not_active IP Right Cessation
- 2005-02-22 NO NO20050956A patent/NO324821B1/no not_active IP Right Cessation
- 2005-02-24 ZA ZA2005/01641A patent/ZA200501641B/en unknown
- 2005-02-28 CO CO05018509A patent/CO5580742A2/es not_active Application Discontinuation
- 2005-06-28 HK HK05105362A patent/HK1072559A1/xx not_active IP Right Cessation
-
2007
- 2007-12-18 CY CY20071101601T patent/CY1107096T1/el unknown
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Effective date: 20150728 |