AR033659A1 - El compuesto 2-(3,5-bis -trifluormetil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida), su uso, un procedimiento para prepararlo y un medicamento que lo contiene - Google Patents

El compuesto 2-(3,5-bis -trifluormetil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida), su uso, un procedimiento para prepararlo y un medicamento que lo contiene

Info

Publication number
AR033659A1
AR033659A1 ARP000106217A ARP000106217A AR033659A1 AR 033659 A1 AR033659 A1 AR 033659A1 AR P000106217 A ARP000106217 A AR P000106217A AR P000106217 A ARP000106217 A AR P000106217A AR 033659 A1 AR033659 A1 AR 033659A1
Authority
AR
Argentina
Prior art keywords
compound
bis
phenyl
prepare
methyl
Prior art date
Application number
ARP000106217A
Other languages
English (en)
Spanish (es)
Inventor
Theresa Maria Ballard
Guy Andrew Higgins
Torsten Hoffmann
Sonia Maria Poli
Andrew Sleight
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR033659A1 publication Critical patent/AR033659A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ARP000106217A 1999-11-29 2000-11-27 El compuesto 2-(3,5-bis -trifluormetil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida), su uso, un procedimiento para prepararlo y un medicamento que lo contiene AR033659A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99123685 1999-11-29

Publications (1)

Publication Number Publication Date
AR033659A1 true AR033659A1 (es) 2004-01-07

Family

ID=8239481

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000106217A AR033659A1 (es) 1999-11-29 2000-11-27 El compuesto 2-(3,5-bis -trifluormetil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida), su uso, un procedimiento para prepararlo y un medicamento que lo contiene

Country Status (49)

Country Link
EP (1) EP1103545B1 (OSRAM)
JP (1) JP3480835B2 (OSRAM)
KR (1) KR100390117B1 (OSRAM)
CN (1) CN1152016C (OSRAM)
AR (1) AR033659A1 (OSRAM)
AT (1) ATE253561T1 (OSRAM)
AU (1) AU775292B2 (OSRAM)
BG (1) BG64622B1 (OSRAM)
BR (1) BRPI0005616B8 (OSRAM)
CA (1) CA2326529C (OSRAM)
CO (1) CO5251405A1 (OSRAM)
CZ (1) CZ299286B6 (OSRAM)
DE (2) DE60006340T2 (OSRAM)
DK (1) DK1103545T3 (OSRAM)
DO (1) DOP2000000106A (OSRAM)
EA (1) EA004404B1 (OSRAM)
ES (2) ES2208205T3 (OSRAM)
FR (1) FR2801590A1 (OSRAM)
GB (1) GB2356863A (OSRAM)
GC (1) GC0000151A (OSRAM)
GE (1) GEP20022763B (OSRAM)
GT (1) GT200000197A (OSRAM)
HR (1) HRP20000809A2 (OSRAM)
HU (1) HU224703B1 (OSRAM)
ID (1) ID28483A (OSRAM)
IL (1) IL139868A (OSRAM)
IS (1) IS2212B (OSRAM)
IT (1) IT1320120B1 (OSRAM)
JO (1) JO2298B1 (OSRAM)
MA (1) MA26754A1 (OSRAM)
MX (1) MXPA00011672A (OSRAM)
MY (1) MY127426A (OSRAM)
NO (1) NO317264B1 (OSRAM)
NZ (1) NZ508386A (OSRAM)
OA (1) OA11513A (OSRAM)
PA (1) PA8507201A1 (OSRAM)
PE (1) PE20010901A1 (OSRAM)
PL (1) PL195957B1 (OSRAM)
PT (1) PT1103545E (OSRAM)
SG (1) SG97171A1 (OSRAM)
SI (1) SI1103545T1 (OSRAM)
SK (1) SK285373B6 (OSRAM)
SV (1) SV2002000227A (OSRAM)
TN (1) TNSN00226A1 (OSRAM)
TR (1) TR200302077T4 (OSRAM)
UA (1) UA70326C2 (OSRAM)
UY (1) UY26458A1 (OSRAM)
YU (1) YU73400A (OSRAM)
ZA (1) ZA200006964B (OSRAM)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE277905T1 (de) * 1999-02-24 2004-10-15 Hoffmann La Roche 4-phenylpyridinderivate und deren verwendung als nk-1 rezeptorantagonisten
PL350427A1 (en) 1999-02-24 2002-12-16 Hoffmann La Roche Phenyl− and pyridinyl derivatives as neurokinin 1 antagonists
WO2002006236A1 (en) * 2000-07-14 2002-01-24 F. Hoffmann-La Roche Ag N-oxides as nk1 receptor antagonist prodrugs of 4-phenyl-pyridine derivatives
TWI287003B (en) * 2000-07-24 2007-09-21 Hoffmann La Roche 4-phenyl-pyridine derivatives
TWI259180B (en) * 2000-08-08 2006-08-01 Hoffmann La Roche 4-Phenyl-pyridine derivatives
US20030083345A1 (en) * 2001-07-10 2003-05-01 Torsten Hoffmann Method of treatment and/or prevention of brain, spinal or nerve injury
KR20040077910A (ko) * 2002-01-31 2004-09-07 에프. 호프만-라 로슈 아게 프리프로타키키닌 유전자의 유전자 다형성
CA2530886C (en) 2003-07-03 2013-05-28 F. Hoffmann-La Roche Ag Dual nk1/nk3 antagonists for treating schizophrenia
TWI280239B (en) 2003-07-15 2007-05-01 Hoffmann La Roche Process for preparation of pyridine derivatives
ATE500224T1 (de) 2004-07-06 2011-03-15 Hoffmann La Roche Herstellungsverfahren für carboxamid-pyridin- derivate als zwischenprodukte bei der synthese von nk-1-rezeptor-antagonisten
JP2008531509A (ja) 2005-02-25 2008-08-14 エフ．ホフマン−ラ ロシュ アーゲー 医薬品成分の改良された分散性を有する錠剤
AU2006226665B2 (en) 2005-03-23 2011-01-27 Helsinn Healthcare S.A. Metabolites for NK-I antagonists for emesis
AU2006298898B2 (en) * 2005-09-23 2011-06-30 F. Hoffmann-La Roche Ag Novel dosage formulation
KR20090112722A (ko) 2007-01-24 2009-10-28 글락소 그룹 리미티드 3,5-디아미노-6-(2,3-디클로로페닐)-1,2,4-트리아진 또는 ｒ(-)-2,4-디아미노-5-(2,3-디클로로페닐)-6-플루오로메틸 피리미딘 및 ｎｋ1을 포함하는 제약 조성물
US8426450B1 (en) * 2011-11-29 2013-04-23 Helsinn Healthcare Sa Substituted 4-phenyl pyridines having anti-emetic effect
BR112015021982B1 (pt) 2013-03-15 2022-12-13 Global Blood Therapeutics, Inc Compostos e seus usos para a modulação de hemoglobina
CA2930008A1 (en) 2013-11-08 2015-05-14 Kissei Pharmaceutical Co., Ltd. Carboxymethyl piperidine derivative
FI3102208T4 (fi) 2014-02-07 2024-09-23 Global Blood Therapeutics Inc 2-hydroksi-6-((2-(1-isopropyyli-1h-pyratsol-5-yyli)pyridin-3-yyli)metoksi)bentsaldehydin vapaan emäksen kiteinen polymorfi
TWI649307B (zh) 2014-05-07 2019-02-01 日商橘生藥品工業股份有限公司 Cyclohexylpyridine derivative
KR101948238B1 (ko) 2016-08-19 2019-02-14 (주)케어젠 미녹시딜과 펩타이드의 결합체
KR102328682B1 (ko) 2018-08-27 2021-11-18 주식회사 대웅제약 신규한 헤테로사이클릭아민 유도체 및 이를 포함하는 약학 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE195867T1 (de) * 1991-09-20 2000-09-15 Glaxo Group Ltd Neue medizinische indikation für tachykinin- antagonisten
CA2099233A1 (en) * 1992-06-29 1993-12-30 Conrad P. Dorn Morpholine and thiomorpholine tachykinin receptor antagonists
IL111960A (en) * 1993-12-17 1999-12-22 Merck & Co Inc Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
WO1995018124A1 (en) * 1993-12-29 1995-07-06 Merck Sharp & Dohme Limited Substituted morpholine derivatives and their use as therapeutic agents
TW385308B (en) * 1994-03-04 2000-03-21 Merck & Co Inc Prodrugs of morpholine tachykinin receptor antagonists
NO309272B1 (no) * 1995-03-24 2001-01-08 Takeda Chemical Industries Ltd Cykliske forbindelser, preparater inneholdende forbindelsene samt mellomprodukter for fremstilling av forbindelsene
US5972938A (en) * 1997-12-01 1999-10-26 Merck & Co., Inc. Method for treating or preventing psychoimmunological disorders
ATE277905T1 (de) * 1999-02-24 2004-10-15 Hoffmann La Roche 4-phenylpyridinderivate und deren verwendung als nk-1 rezeptorantagonisten
US6303790B1 (en) * 1999-11-29 2001-10-16 Hoffman-La Roche Inc. Process for the preparation of pyridine derivatives
WO2002006236A1 (en) * 2000-07-14 2002-01-24 F. Hoffmann-La Roche Ag N-oxides as nk1 receptor antagonist prodrugs of 4-phenyl-pyridine derivatives
TWI287003B (en) * 2000-07-24 2007-09-21 Hoffmann La Roche 4-phenyl-pyridine derivatives
TWI259180B (en) * 2000-08-08 2006-08-01 Hoffmann La Roche 4-Phenyl-pyridine derivatives

Also Published As

Publication number Publication date
DE10058310A1 (de) 2001-05-31
IS2212B (is) 2007-02-15
IS5725A (is) 2001-05-29
ID28483A (id) 2001-05-31
CN1297888A (zh) 2001-06-06
GB2356863A (en) 2001-06-06
CO5251405A1 (es) 2003-02-28
GEP20022763B (en) 2002-08-26
SK17932000A3 (sk) 2001-11-06
FR2801590A1 (fr) 2001-06-01
EA004404B1 (ru) 2004-04-29
SI1103545T1 (en) 2004-02-29
NZ508386A (en) 2003-02-28
ZA200006964B (en) 2001-06-05
PL195957B1 (pl) 2007-11-30
BR0005616A (pt) 2001-07-17
IL139868A (en) 2009-09-01
BG64622B1 (bg) 2005-09-30
CZ299286B6 (cs) 2008-06-04
BRPI0005616B8 (pt) 2021-07-06
JP3480835B2 (ja) 2003-12-22
HU224703B1 (en) 2006-01-30
NO20006012L (no) 2001-05-30
BRPI0005616B1 (pt) 2017-12-12
SK285373B6 (sk) 2006-12-07
DOP2000000106A (es) 2002-07-30
HUP0004725A2 (hu) 2002-04-29
IT1320120B1 (it) 2003-11-18
AU7178700A (en) 2001-05-31
UY26458A1 (es) 2001-05-31
AU775292B2 (en) 2004-07-29
DE60006340T2 (de) 2004-09-09
GC0000151A (en) 2005-06-29
PE20010901A1 (es) 2001-09-20
CA2326529A1 (en) 2001-05-29
JO2298B1 (en) 2005-09-12
OA11513A (fr) 2004-02-03
KR100390117B1 (ko) 2003-07-04
MA26754A1 (fr) 2004-12-20
TR200302077T4 (tr) 2004-01-21
UA70326C2 (en) 2004-10-15
ES2208205T3 (es) 2004-06-16
GT200000197A (es) 2002-05-22
SV2002000227A (es) 2002-02-05
BG104992A (en) 2001-11-30
CA2326529C (en) 2009-12-22
PL344147A1 (en) 2001-06-04
IL139868A0 (en) 2002-02-10
NO20006012D0 (no) 2000-11-28
SG97171A1 (en) 2003-07-18
TNSN00226A1 (fr) 2002-05-30
DK1103545T3 (da) 2004-03-15
EP1103545A1 (en) 2001-05-30
MXPA00011672A (es) 2002-08-20
MY127426A (en) 2006-11-30
HK1036759A1 (en) 2002-01-18
HRP20000809A2 (en) 2001-12-31
PT1103545E (pt) 2004-03-31
NO317264B1 (no) 2004-09-27
HU0004725D0 (OSRAM) 2001-02-28
EA200001114A3 (ru) 2001-12-24
PA8507201A1 (es) 2002-02-21
EP1103545B1 (en) 2003-11-05
ATE253561T1 (de) 2003-11-15
CN1152016C (zh) 2004-06-02
EA200001114A2 (ru) 2001-08-27
YU73400A (sh) 2003-02-28
DE60006340D1 (de) 2003-12-11
GB0028566D0 (en) 2001-01-10
ES2171134A1 (es) 2002-08-16
ITMI20002575A1 (it) 2002-05-29
KR20010051983A (ko) 2001-06-25
CZ20004399A3 (cs) 2001-07-11
JP2001151754A (ja) 2001-06-05

Similar Documents

Publication Publication Date Title
AR033659A1 (es) El compuesto 2-(3,5-bis -trifluormetil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida), su uso, un procedimiento para prepararlo y un medicamento que lo contiene
AR009052A1 (es) Tienopirimidinas, un procedimiento para su preparacion, empleo de las mismas para preparar un medicamento, preparaciones farmaceuticas que lascontienen y un procedimiento para obtener estas preparaciones farmaceuticas
BR0314393A (pt) Piperazinas heterocìclicas substituìdas para o tratamento de esquizofrenia
UY38880A (es) Degradadores bifuncionales de brd9 y sus métodos de uso
AR020727A1 (es) Uso de compuestos derivados 3-amino-4-aril-maleimidas para la preparacion de medicamentos para condiciones asociadas a una necesidad de inhibicion de lagsk-3, dichos compuestos, procedimiento para su preparacion y composiciones farmaceuticas que los comprenden
UY28059A1 (es) Nuevos derivados de dihidropirimido (4,5-d) pirimidona sustituida por amino. fabricacion y uso de los mismos como agentes farmaceuticos.
ES2134859T3 (es) Derivados de 4-carboxoamido-piperidina, productos intermedios y uso como antagonistas de neurokinina.
AR036208A1 (es) Compuesto polimorfo estable de flibanserina, procedimiento industrial para su preparacion, y uso del mismo para preparar medicamentos
CO5271715A1 (es) 7-aza-indolin-2-onas sustituidas en 4 y su uso como inhibidores de proteiuna quinasa
ECSP055747A (es) Antagonistas de cgrp elegidos, procedimiento para su preparación, así como su empleo como medicamentos
ES2163071T3 (es) Sulfonamidas y su utilizacion.
BR9910583A (pt) Aminotetralinas n-substituìdas como ligantes para o receptor de neuropeptìdeo y y5 úteis no tratamento de obesidade e outros distúrbios
DE69837809D1 (de) Apolipoprotein a-i agonisten sowie deren verwendung zur behandlung dislipidemischer erkrankungen
CO4810373A1 (es) Compuestos azapoliciclicos condensados con arilo
ECSP055746A (es) Antagonistas de cgrp elegidos, procedimiento para su preparación, así como su empleo como medicamentos
CO5180642A1 (es) Compuestos sustituidos de piperidina, procesos para su prepa racion, composiciones farmaceuticas que los contienen y su utilizacion
GT199800046A (es) Compuestos de pirazina.
PT1263730E (pt) Derivados amina para o tratamento de apoptose
PA8549901A1 (es) Uso de los antagonistas del receptor nk-1 para el tratamiento de lesiones cerebrales, espinales o neuronales
AR006360A1 (es) Derivados de 1,2,3,4-tetrahidronaftaleno substituidos, uso de los mismos para la preparacion de medicamentos y procedimiento para su preparacion.
AR028475A1 (es) Derivados de azaindol y uso de los mismos para la manufactura de un medicamento para el tratamiento de la depresion.
AR005102A1 (es) Compuestos derivados de octahidro-pirrolo [1,2-a]-pirazina 2,7-sustituidos, composiciones farmaceuticas y uso de dichos compuestos para la fabricacion deun medicamento.
UY29924A1 (es) Medicamentos en base a 11-(4-(2-(2-hidroxietoxi)etil)-1-piperazinil)dibenzo-(b,f)(1,4)tiazepina y sus sales farmacéuticamente aceptables
CO5590934A2 (es) Procedimiento de preparacion de derivados de equinocandina
AR027578A1 (es) Derivados de indano

Legal Events

Date Code Title Description
FB Suspension of granting procedure