PA8549901A1 - Uso de los antagonistas del receptor nk-1 para el tratamiento de lesiones cerebrales, espinales o neuronales - Google Patents
Uso de los antagonistas del receptor nk-1 para el tratamiento de lesiones cerebrales, espinales o neuronalesInfo
- Publication number
- PA8549901A1 PA8549901A1 PA20028549901A PA8549901A PA8549901A1 PA 8549901 A1 PA8549901 A1 PA 8549901A1 PA 20028549901 A PA20028549901 A PA 20028549901A PA 8549901 A PA8549901 A PA 8549901A PA 8549901 A1 PA8549901 A1 PA 8549901A1
- Authority
- PA
- Panama
- Prior art keywords
- treatment
- spinal
- brain
- receiver
- magnesium salt
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 3
- 230000001537 neural effect Effects 0.000 title abstract 3
- 210000004556 brain Anatomy 0.000 title abstract 2
- 230000006378 damage Effects 0.000 title abstract 2
- 159000000003 magnesium salts Chemical class 0.000 abstract 3
- 239000002131 composite material Substances 0.000 abstract 1
- 229960003966 nicotinamide Drugs 0.000 abstract 1
- 239000011570 nicotinamide Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000003405 preventing effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA INVENCION SE REFIERE AL USO DE UN ANTAGONISTA DEL RECEPTOR NK-1, EN COMBINACION OPCIONALMENTE CON UNA SAL DE MAGNESIO, PARA EL TRATAMIENTO Y/O PREVENCION DE LESIONES CEREBRALES, ESPINALES O NEURONALES, EN DONDE DICHO ANTAGONISTA DEL RECEPTOR NK-1 ES UN COMPUESTO DE FORMULA GENERAL I, EN DONDE LOS SIGNIFICADOS DE R, R1, R2, R2', R3, R4 SE EXPLICAN EN LA ESPECIFICACION Y LAS SALES DE ADICION ACIDA FARMACEUTICAMENTE ACEPTABLES Y LOS PRO-FARMACOS DE LOS MISMOS TANTO SOLOS O EN COMBINACION CON UNA SAL DE MAGNESIO. SE EJEMPLIFICA EL USO DE N-(3,5,-BIS-TRIFLUOROMETIL-BENCIL)-N-METIL-6-(4-METIL-PIPERAZIN-1-IL)-4-O-TOLIL-NICOTINAMIDA. LA INVENCION TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UNO O MAS DE TALES ANTAGONISTAS DEL RECEPTOR NK-1, EN COMBINACION OPCIONALMENTE CON UNA SAL DE MAGNESIO, Y UN EXCIPIENTE FARMACEUTICAMENTE ACEPTABLE PARA EL TRATAMIENTO Y/O PREVENCION DE LESIONES CEREBRALES, ESPINALES O NEURONALES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01116812 | 2001-07-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8549901A1 true PA8549901A1 (es) | 2003-01-24 |
Family
ID=8178001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20028549901A PA8549901A1 (es) | 2001-07-10 | 2002-07-05 | Uso de los antagonistas del receptor nk-1 para el tratamiento de lesiones cerebrales, espinales o neuronales |
Country Status (24)
Country | Link |
---|---|
US (3) | US20030083345A1 (es) |
EP (2) | EP1406618A2 (es) |
JP (1) | JP2004536119A (es) |
KR (1) | KR100589106B1 (es) |
CN (1) | CN100346789C (es) |
AR (1) | AR037008A1 (es) |
AU (1) | AU2002328837B2 (es) |
BR (1) | BR0210893A (es) |
CA (1) | CA2451566C (es) |
GT (1) | GT200200143A (es) |
HK (1) | HK1068266A1 (es) |
HR (1) | HRP20031071A2 (es) |
HU (1) | HUP0401210A3 (es) |
IL (1) | IL159350A0 (es) |
MX (1) | MXPA04000278A (es) |
NO (1) | NO332847B1 (es) |
NZ (1) | NZ530107A (es) |
PA (1) | PA8549901A1 (es) |
PE (1) | PE20030238A1 (es) |
PL (1) | PL211246B1 (es) |
RU (1) | RU2304435C2 (es) |
UY (1) | UY27374A1 (es) |
WO (1) | WO2003006016A2 (es) |
ZA (1) | ZA200400138B (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE400556T1 (de) * | 2000-07-14 | 2008-07-15 | Hoffmann La Roche | N-oxide als nk1-rezeptorantagonistenprodrugs von 4-phenylpyridinderivaten |
NZ544244A (en) * | 2003-07-03 | 2008-10-31 | Hoffmann La Roche | Dual NK1/NK3 antagonists for treating schizophrenia |
GB0410215D0 (en) * | 2004-05-07 | 2004-06-09 | Lescroart Pol | Nerve damage |
CA2572645C (en) | 2004-07-06 | 2011-01-18 | F. Hoffmann-La Roche Ag | Process for preparing carboxamide derivatives used as intermediates in the synthesis of nk-1 receptor antagonists |
US20060030600A1 (en) * | 2004-08-06 | 2006-02-09 | Patrick Schnider | Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia |
EP1856052B1 (en) * | 2005-02-22 | 2009-09-02 | F.Hoffmann-La Roche Ag | Nk1 antagonists |
EP1855655A2 (en) | 2005-02-25 | 2007-11-21 | F. Hoffmann-Roche AG | Tablets with improved drug substance dispersibility |
PL1863767T3 (pl) * | 2005-03-23 | 2009-08-31 | Helsinn Healthcare Sa | Metabolity antagonistów NK-1 do leczenia wymiotów |
EP3696174A1 (en) | 2005-11-08 | 2020-08-19 | Vertex Pharmaceuticals Incorporated | Heterocyclic modulators of atp-binding cassette transporters |
US7671221B2 (en) | 2005-12-28 | 2010-03-02 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
US7754739B2 (en) | 2007-05-09 | 2010-07-13 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
DE102007018151A1 (de) * | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
CN101687842B (zh) | 2007-05-09 | 2013-03-06 | 沃泰克斯药物股份有限公司 | Cftr调节剂 |
KR20100055430A (ko) * | 2007-07-19 | 2010-05-26 | 애들레이드 리서치 앤드 이노베이션 피티와이 리미티드 | 두개내압 감소 방법 |
CN103626744B (zh) | 2007-12-07 | 2016-05-11 | 沃泰克斯药物股份有限公司 | 3-(6-(1-(2,2-二氟苯并[d][1,3]间二氧杂环戊烯-5-基)环丙烷甲酰氨基)-3-甲基吡啶-2-基)苯甲酸的固体形式 |
LT2639223T (lt) | 2007-12-07 | 2017-06-26 | Vertex Pharmaceuticals Incorporated | Cikloalkilkarboksiamido-piridino benzenkarboksirūgščių gamybos būdas |
ES2647531T3 (es) | 2008-02-28 | 2017-12-22 | Vertex Pharmaceuticals Incorporated | Derivados de heteroarilo como moduladores de CFTR |
GB0808747D0 (en) * | 2008-05-14 | 2008-06-18 | Glaxo Wellcome Mfg Pte Ltd | Novel compounds |
WO2011127241A2 (en) | 2010-04-07 | 2011-10-13 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyriodin-2-yl)benzoic acid and administration thereof |
EP3016657B1 (en) * | 2013-07-02 | 2019-06-26 | Eustralis Pharmaceuticals Limited (Trading as Pressura Neuro) | Method for preventing and/or treating chronic traumatic encephalopathy-ii |
RU2016103099A (ru) * | 2013-07-02 | 2017-08-07 | Юстрэлиз Фармасьютикалз Лимитед (Трейдинг Эз Пресшура Нейро) | Способ предотвращения и/или лечения хронической травматической энцефалопатии - i |
WO2015000035A1 (en) * | 2013-07-02 | 2015-01-08 | Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) | Method for preventing and/or treating chronic traumatic encephalopathy-iv |
KR20160078997A (ko) | 2013-11-08 | 2016-07-05 | 깃세이 야쿠힌 고교 가부시키가이샤 | 카복시메틸피페리딘 유도체 |
KR102280372B1 (ko) | 2013-11-12 | 2021-07-22 | 버텍스 파마슈티칼스 인코포레이티드 | Cftr 매개된 질환 치료용 약제학적 조성물의 제조 방법 |
TWI649307B (zh) | 2014-05-07 | 2019-02-01 | 日商橘生藥品工業股份有限公司 | Cyclohexylpyridine derivative |
CN107110831B (zh) | 2014-11-18 | 2020-02-21 | 弗特克斯药品有限公司 | 进行高通量试验高效液相色谱的方法 |
MX2020008138A (es) | 2018-02-02 | 2020-10-19 | Eustralis Pharmaceuticals Ltd Trading As Pressura Neuro | Formulaciones parentales y usos de estas. |
KR101970099B1 (ko) * | 2018-02-07 | 2019-04-17 | 한국과학기술연구원 | 척수 손상의 예방 및 치료용 조성물 |
KR102005019B1 (ko) * | 2018-04-04 | 2019-07-31 | 한국과학기술연구원 | 뇌졸중의 예방 및 치료용 조성물 |
AU2020337177A1 (en) * | 2019-08-23 | 2022-04-07 | Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) | Therapeutic methods and uses thereof |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4745123A (en) * | 1986-02-18 | 1988-05-17 | Warner-Lambert Company | Substituted tetrahydro-3-pyridine-carboxylic acid, ester, and amide cholinergic agents |
IL111002A (en) * | 1993-09-22 | 1998-09-24 | Glaxo Group Ltd | History of piperidine, their preparation and the pharmaceutical preparations containing them |
US6175013B1 (en) * | 1994-06-10 | 2001-01-16 | Eli Lilly And Company | Imidazolinyl tachykinin receptor antagonists |
US5607947A (en) * | 1995-02-21 | 1997-03-04 | Eli Lilly And Company | Pyrrolidinyl tachykinin receptor antagonists |
IL116249A (en) * | 1994-12-12 | 2003-07-06 | Pfizer | Nk-1 receptor antagonists for the treatment of neuronal damage and stroke |
TW382017B (en) * | 1995-12-27 | 2000-02-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
JP2002506459A (ja) * | 1997-06-27 | 2002-02-26 | メルク シヤープ エンド ドーム リミテツド | 置換された3−(ベンジルアミノ)ピペリジン誘導体およびその治療薬としての使用 |
US5972938A (en) * | 1997-12-01 | 1999-10-26 | Merck & Co., Inc. | Method for treating or preventing psychoimmunological disorders |
PT1157005E (pt) * | 1999-02-24 | 2005-02-28 | Hoffmann La Roche | Derivados de 3-fenilpirina e a sua utilizacao como antagonistas do receptor nk-1 |
EP1394150B1 (en) * | 1999-02-24 | 2011-01-19 | F. Hoffmann-La Roche AG | 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists |
GB9923748D0 (en) * | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
US6303790B1 (en) * | 1999-11-29 | 2001-10-16 | Hoffman-La Roche Inc. | Process for the preparation of pyridine derivatives |
TR200302077T4 (tr) * | 1999-11-29 | 2004-01-21 | F. Hoffmann-La Roche Ag | 2-(3,5-Bis-Trifluorometil-fenil)-N-metil-N- (6-morfonil-4-il-4-O-tolil-piridin-3-il)- izobütiramit |
AUPQ514600A0 (en) * | 2000-01-18 | 2000-02-10 | James Cook University | Brain injury treatment |
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2002
- 2002-07-02 US US10/187,587 patent/US20030083345A1/en not_active Abandoned
- 2002-07-03 HU HU0401210A patent/HUP0401210A3/hu unknown
- 2002-07-03 WO PCT/EP2002/007323 patent/WO2003006016A2/en active IP Right Grant
- 2002-07-03 RU RU2004102397/15A patent/RU2304435C2/ru active
- 2002-07-03 MX MXPA04000278A patent/MXPA04000278A/es active IP Right Grant
- 2002-07-03 CA CA2451566A patent/CA2451566C/en not_active Expired - Lifetime
- 2002-07-03 EP EP02764617A patent/EP1406618A2/en not_active Withdrawn
- 2002-07-03 EP EP05017203A patent/EP1621195A3/en not_active Withdrawn
- 2002-07-03 CN CNB028135423A patent/CN100346789C/zh not_active Expired - Lifetime
- 2002-07-03 NZ NZ530107A patent/NZ530107A/en unknown
- 2002-07-03 PL PL369535A patent/PL211246B1/pl unknown
- 2002-07-03 AU AU2002328837A patent/AU2002328837B2/en not_active Expired
- 2002-07-03 IL IL15935002A patent/IL159350A0/xx unknown
- 2002-07-03 JP JP2003511822A patent/JP2004536119A/ja active Pending
- 2002-07-03 KR KR1020047000395A patent/KR100589106B1/ko active IP Right Grant
- 2002-07-03 BR BR0210893-3A patent/BR0210893A/pt not_active IP Right Cessation
- 2002-07-05 PA PA20028549901A patent/PA8549901A1/es unknown
- 2002-07-08 PE PE2002000610A patent/PE20030238A1/es not_active Application Discontinuation
- 2002-07-08 AR ARP020102546A patent/AR037008A1/es unknown
- 2002-07-09 UY UY27374A patent/UY27374A1/es not_active Application Discontinuation
- 2002-07-09 GT GT200200143A patent/GT200200143A/es unknown
-
2003
- 2003-12-22 HR HR20031071A patent/HRP20031071A2/xx not_active Application Discontinuation
-
2004
- 2004-01-07 NO NO20040057A patent/NO332847B1/no not_active IP Right Cessation
- 2004-01-08 ZA ZA2004/00138A patent/ZA200400138B/en unknown
-
2005
- 2005-01-17 HK HK05100430A patent/HK1068266A1/xx not_active IP Right Cessation
-
2006
- 2006-07-05 US US11/481,216 patent/US20060247240A1/en not_active Abandoned
-
2010
- 2010-09-21 US US12/886,691 patent/US20110053954A1/en not_active Abandoned
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