BRPI0514661B8 - antagonistas de vasopressina v1a, composição farmacêutica e uso dos referidos antagonistas - Google Patents

antagonistas de vasopressina v1a, composição farmacêutica e uso dos referidos antagonistas

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Publication number
BRPI0514661B8
BRPI0514661B8 BRPI0514661A BRPI0514661A BRPI0514661B8 BR PI0514661 B8 BRPI0514661 B8 BR PI0514661B8 BR PI0514661 A BRPI0514661 A BR PI0514661A BR PI0514661 A BRPI0514661 A BR PI0514661A BR PI0514661 B8 BRPI0514661 B8 BR PI0514661B8
Authority
BR
Brazil
Prior art keywords
antagonists
vasopressin
pharmaceutical composition
dysmenorrhoea
compounds
Prior art date
Application number
BRPI0514661A
Other languages
English (en)
Inventor
John Baxter Andrew
Heeney Celine
Lee Stockley Martin
Bryan Roe Michael
Hudson Peter
Handy Rachel
Batt Andrzej Roman
Original Assignee
Ferring Bv
Vantia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv, Vantia Ltd filed Critical Ferring Bv
Publication of BRPI0514661A publication Critical patent/BRPI0514661A/pt
Publication of BRPI0514661B1 publication Critical patent/BRPI0514661B1/pt
Publication of BRPI0514661B8 publication Critical patent/BRPI0514661B8/pt

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    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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Abstract

antagonistas de vasopressina v1a a presente invenção concerne a compostos, entre outras coisas, de acordo com a fórmula geral 1a. os compostos de acordo com a invenção são antagonistas de receptor de vasopressina v~ 1a~. as composições farmacêuticas das compostos são úteis como tratamento de dismenorréia.
BRPI0514661A 2004-08-24 2005-08-24 antagonistas de vasopressina v1a, composição farmacêutica e uso dos referidos antagonistas BRPI0514661B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60355704P 2004-08-24 2004-08-24
EP04104062A EP1632494A1 (en) 2004-08-24 2004-08-24 Vasopressin v1a antagonists
EP04104062.7 2004-08-24
US60/603,557 2004-08-24
PCT/DK2005/000540 WO2006021213A2 (en) 2004-08-24 2005-08-24 Vasopressin v1a antagonists

Publications (3)

Publication Number Publication Date
BRPI0514661A BRPI0514661A (pt) 2008-06-17
BRPI0514661B1 BRPI0514661B1 (pt) 2018-08-07
BRPI0514661B8 true BRPI0514661B8 (pt) 2021-05-25

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ID=34929482

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Application Number Title Priority Date Filing Date
BRPI0514661A BRPI0514661B8 (pt) 2004-08-24 2005-08-24 antagonistas de vasopressina v1a, composição farmacêutica e uso dos referidos antagonistas

Country Status (16)

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US (2) US8202858B2 (pt)
EP (5) EP1632494A1 (pt)
JP (2) JP4926058B2 (pt)
KR (2) KR101155401B1 (pt)
CN (2) CN101563347A (pt)
AT (1) ATE557026T1 (pt)
AU (4) AU2005276790B2 (pt)
BR (1) BRPI0514661B8 (pt)
CA (4) CA2688912A1 (pt)
ES (1) ES2638114T3 (pt)
IL (1) IL178709A (pt)
MX (1) MX2007001392A (pt)
NO (1) NO20071560L (pt)
RU (1) RU2370497C2 (pt)
WO (1) WO2006021213A2 (pt)
ZA (1) ZA200701257B (pt)

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