ATE435210T1 - Tetrahydroisochinolylacetamidderivate zur verwendung als orexinrezeptorantagonisten - Google Patents

Tetrahydroisochinolylacetamidderivate zur verwendung als orexinrezeptorantagonisten

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Publication number
ATE435210T1
ATE435210T1 AT04722563T AT04722563T ATE435210T1 AT E435210 T1 ATE435210 T1 AT E435210T1 AT 04722563 T AT04722563 T AT 04722563T AT 04722563 T AT04722563 T AT 04722563T AT E435210 T1 ATE435210 T1 AT E435210T1
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AT
Austria
Prior art keywords
receptor antagonists
derivatives
orexin receptor
tetrahydroisochinolylacetamide
preparation
Prior art date
Application number
AT04722563T
Other languages
English (en)
Inventor
Hamed Aissaoui
Martine Clozel
Thomas Weller
Ralf Koberstein
Thierry Sifferlen
Walter Fischli
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE435210T1 publication Critical patent/ATE435210T1/de

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    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
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    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
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    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
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AT04722563T 2003-03-26 2004-03-23 Tetrahydroisochinolylacetamidderivate zur verwendung als orexinrezeptorantagonisten ATE435210T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP0303143 2003-03-26
PCT/EP2004/003057 WO2004085403A1 (en) 2003-03-26 2004-03-23 Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists

Publications (1)

Publication Number Publication Date
ATE435210T1 true ATE435210T1 (de) 2009-07-15

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AT04722563T ATE435210T1 (de) 2003-03-26 2004-03-23 Tetrahydroisochinolylacetamidderivate zur verwendung als orexinrezeptorantagonisten

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Country Link
US (1) US20060178515A1 (de)
EP (1) EP1611104B1 (de)
JP (1) JP4637089B2 (de)
KR (1) KR20050114242A (de)
CN (1) CN100432056C (de)
AT (1) ATE435210T1 (de)
AU (1) AU2004224156B2 (de)
BR (1) BRPI0408681A (de)
CA (1) CA2518945A1 (de)
DE (1) DE602004021786D1 (de)
ES (1) ES2327737T3 (de)
MX (1) MXPA05010137A (de)
RU (1) RU2345985C2 (de)
WO (1) WO2004085403A1 (de)

Families Citing this family (69)

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Publication number Priority date Publication date Assignee Title
RU2378257C2 (ru) * 2004-03-01 2010-01-10 Актелион Фармасьютиклз Лтд Замещенные производные 1,2,3,4-тетрагидроизохинолина
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