AR031658A1 - Procedimiento para la preparacion de 4-haloalquilnicotinonitrilos - Google Patents

Procedimiento para la preparacion de 4-haloalquilnicotinonitrilos

Info

Publication number
AR031658A1
AR031658A1 ARP010105750A ARP010105750A AR031658A1 AR 031658 A1 AR031658 A1 AR 031658A1 AR P010105750 A ARP010105750 A AR P010105750A AR P010105750 A ARP010105750 A AR P010105750A AR 031658 A1 AR031658 A1 AR 031658A1
Authority
AR
Argentina
Prior art keywords
formula
hal
haloalkyl
preparation
reaction
Prior art date
Application number
ARP010105750A
Other languages
English (en)
Original Assignee
Aventis Cropscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2000161967 external-priority patent/DE10061967A1/de
Priority claimed from DE2001120819 external-priority patent/DE10120819A1/de
Priority claimed from DE2001144411 external-priority patent/DE10144411A1/de
Application filed by Aventis Cropscience Gmbh filed Critical Aventis Cropscience Gmbh
Publication of AR031658A1 publication Critical patent/AR031658A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/27—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups, amino groups and doubly-bound oxygen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/30—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same unsaturated acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Abstract

Los haloalquilnicotinitrilos de formula (1) son adecuados como productos intermedios en la preparacion de agentes para combatir organismos perjudiciales y son obtenibles mediante un procedimiento en el cual: a) se hace reaccionar una 3-amino-1-haloalquil-2-propen-1-ona de formula (2):RF-C(O)-CH=CH-NH2 en una reaccion de condensacion con un compuesto de la formula (3) a (7): (R1Z)CH=CH-CN (3); (R1Z)2CH-CH2-CN (4); Hal-CH=CH-CN (5); Hal2CH-CH2-CN (6); HCsC-CN (7) en las cuales RF significa haloalquilo C1-4; R1 es alquilo; Hal es Cl o Br; y Z es O, S, NR1 u OCO, pudiendo en el caso de la formula (4) adoptar ambos radicales Z los significados enunciados anteriormente de forma independiente entre sí, para dar un compuesto de la formula (8), (9) y/o (10): RF-C(O)-CH=CH-NH-CH=CH-CN (8); RF-C(O)-CH=CH-NH-CH(ZR)-CH2-CN (9); RF-C(O)-CH=CH-NH-CH(Hal)-CH2-CN (10) en las cuales R, Z y Hal tienen los significados anteriormente indicados, siendo el producto de la reaccion b) sometido a una reaccion de cierre de anillo. Productos intermediarios.
ARP010105750A 2000-12-13 2001-12-11 Procedimiento para la preparacion de 4-haloalquilnicotinonitrilos AR031658A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2000161967 DE10061967A1 (de) 2000-12-13 2000-12-13 Verfahren zur Herstellung von 4-Trifluormethylnicotinnitril
DE2001120819 DE10120819A1 (de) 2001-04-27 2001-04-27 Verfahren zur Herstellung von 4-Trifluormethylnicotinnitril
DE2001144411 DE10144411A1 (de) 2001-09-11 2001-09-11 Verfahren zur Herstellung von 3-(Haloalkyl-3-oxo-1-butenylamino)acrylnitrilen

Publications (1)

Publication Number Publication Date
AR031658A1 true AR031658A1 (es) 2003-09-24

Family

ID=27214195

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010105750A AR031658A1 (es) 2000-12-13 2001-12-11 Procedimiento para la preparacion de 4-haloalquilnicotinonitrilos

Country Status (14)

Country Link
US (2) US6541640B2 (es)
EP (1) EP1345906A2 (es)
JP (1) JP2004525091A (es)
KR (1) KR100845376B1 (es)
CN (1) CN1244560C (es)
AR (1) AR031658A1 (es)
AU (1) AU2002235770A1 (es)
BR (1) BR0116124A (es)
CZ (1) CZ20031662A3 (es)
HU (1) HUP0401099A3 (es)
IL (3) IL156359A0 (es)
MX (1) MXPA03005258A (es)
TW (1) TWI222442B (es)
WO (1) WO2002048111A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7015236B2 (en) 2001-11-21 2006-03-21 Sankyo Agro Company, Limited N-heteroarylnicotinamide derivatives
DE10223274A1 (de) * 2002-05-24 2003-12-04 Bayer Cropscience Gmbh Verfahren zur Herstellung von 4-Haloalkylnicotinsäureamiden
CA2757722C (en) 2009-04-01 2018-05-22 Matrix Laboratories Ltd. Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
FR2985857B1 (fr) 2012-01-17 2014-01-03 Hutchinson Cathode pour cellule de batterie lithium-ion, son procede de fabrication et cette batterie l'incorporant.
CN106413766A (zh) 2014-04-01 2017-02-15 克洛克斯科技公司 组织填料组合物及使用方法
JP2022036351A (ja) * 2018-10-30 2022-03-08 日本曹達株式会社 ３－シアノ－４－トリフルオロメチルピリジン若しくはその塩を含有する、土壌処理剤、水田処理剤又は種子処理剤
CN109851552A (zh) * 2018-12-28 2019-06-07 京博农化科技有限公司 一种n-氰甲基-4-（三氟甲基）烟酰胺的合成方法
CN113816901B (zh) * 2021-08-27 2023-08-15 淮北龙溪生物科技有限公司 一种4－三氟甲基烟酰胺的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2994182B2 (ja) * 1992-07-23 1999-12-27 石原産業株式会社 アミド系化合物又はその塩、それらの製造方法及びそれらを含有する有害動物防除剤
JPH0710841A (ja) * 1993-06-21 1995-01-13 Ishihara Sangyo Kaisha Ltd ４−トリフルオロメチルピリジン−３−カルボキサミド系化合物又はその塩、それらの製造方法及びそれらを含有する有害動物防除剤
EP1254883B1 (en) * 1995-05-26 2009-09-23 Ishihara Sangyo Kaisha, Ltd. Process for producing substituted 1,1,1-trifluoro-3-butene-2-ones
DE19725450A1 (de) 1997-06-16 1998-12-17 Hoechst Schering Agrevo Gmbh 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclylpyrimidine, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel
AU3730699A (en) * 1998-05-18 1999-12-06 Sumitomo Chemical Company, Limited Heterocyclic compound
DE10014006A1 (de) * 2000-03-22 2001-09-27 Aventis Cropscience Gmbh Heterocyclische Acylsulfimine, Verfahren zu ihrer Herstellung , sie enthalten Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel
GB0022697D0 (en) * 2000-09-15 2000-11-01 Basf Ag Azo disperse dye mixtures

Also Published As

Publication number Publication date
BR0116124A (pt) 2003-12-09
WO2002048111A2 (de) 2002-06-20
CZ20031662A3 (cs) 2003-09-17
US20020087004A1 (en) 2002-07-04
HUP0401099A3 (en) 2007-02-28
EP1345906A2 (de) 2003-09-24
JP2004525091A (ja) 2004-08-19
WO2002048111A3 (de) 2003-03-27
CN1244560C (zh) 2006-03-08
IL156359A (en) 2009-05-04
US20030109711A1 (en) 2003-06-12
AU2002235770A1 (en) 2002-06-24
MXPA03005258A (es) 2003-09-25
KR100845376B1 (ko) 2008-07-09
IL187126A0 (en) 2008-02-09
KR20030060116A (ko) 2003-07-12
US6864385B2 (en) 2005-03-08
HUP0401099A2 (hu) 2004-09-28
TWI222442B (en) 2004-10-21
CN1479723A (zh) 2004-03-03
US6541640B2 (en) 2003-04-01
IL156359A0 (en) 2004-01-04
IL187126A (en) 2009-08-03

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