AR025735A1 - Compuestos terapeuticos - Google Patents
Compuestos terapeuticosInfo
- Publication number
- AR025735A1 AR025735A1 ARP000104956A ARP000104956A AR025735A1 AR 025735 A1 AR025735 A1 AR 025735A1 AR P000104956 A ARP000104956 A AR P000104956A AR P000104956 A ARP000104956 A AR P000104956A AR 025735 A1 AR025735 A1 AR 025735A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydrogen
- alkyl
- optionally substituted
- alkoxy
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto de formula (1) o una sal, éster, amida o prodroga del mismo; donde X es O, o S, S(O), S(O)2 o NR6 donde R6 es hidrogeno o alquilo C1-6; R5 esun anillo aromático de 6 miembros opcionalmente sustituido que contiene al menos un átomo de nitrogeno, y R1, R2, R3, R4 se seleccionan independientementeentre halogeno, ciano, nitro, alquilsulfanilo C1-3, -N(OH)R7- (donde R7 es hidrogeno o alquilo C1-3), o R9X1- (donde X1 representa un enlace directo, -O-,-CH2-, -OC(O)-, -C(O)-, -S-, -SO-, -SO2-, -NR10C(O)-, -C(O)NR11-, -SO2NR12-, -NR13SO2- o -NR14- (donde R10, R11, R12, R13 y R14 representan cada unoindependientemente hidrogeno, alquilo C1-3 o alcoxi C1-3-alquilo C2-3), y R9 es hidrogeno, hidrocarbilo opcionalmente sustituido, heterociclo opcionalmentesustituido o alcoxi opcionalmente sustituido; siempre que al menos uno entre R2 o R3 sea distinto de hidrogeno. Estos compuestos inhiben la aurora 2 quinasa yson utiles en la preparacion de medicamentos para el tratamiento de enfermedades proliferativas tales como el cáncer. También se presenta una composicionfarmacéutica en base al compuesto indicado.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9922171.5A GB9922171D0 (en) | 1999-09-21 | 1999-09-21 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR025735A1 true AR025735A1 (es) | 2002-12-11 |
Family
ID=10861217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000104956A AR025735A1 (es) | 1999-09-21 | 2000-09-21 | Compuestos terapeuticos |
Country Status (24)
Country | Link |
---|---|
US (1) | US7235559B1 (es) |
EP (1) | EP1218355A1 (es) |
JP (1) | JP2003509500A (es) |
KR (1) | KR20020030123A (es) |
CN (1) | CN1391563A (es) |
AR (1) | AR025735A1 (es) |
AU (1) | AU762697B2 (es) |
BG (1) | BG106526A (es) |
BR (1) | BR0014137A (es) |
CA (1) | CA2384296A1 (es) |
CO (1) | CO5200783A1 (es) |
CZ (1) | CZ20021008A3 (es) |
EE (1) | EE200200118A (es) |
GB (1) | GB9922171D0 (es) |
HK (1) | HK1046685A1 (es) |
HU (1) | HUP0300205A3 (es) |
IL (1) | IL148496A0 (es) |
IS (1) | IS6310A (es) |
NO (1) | NO20021400L (es) |
PL (1) | PL354870A1 (es) |
SK (1) | SK3872002A3 (es) |
TR (1) | TR200200717T2 (es) |
WO (1) | WO2001021597A1 (es) |
ZA (1) | ZA200202232B (es) |
Families Citing this family (73)
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NZ522696A (en) | 2000-06-28 | 2004-08-27 | Astrazeneca Ab | Substituted quinazoline derivatives and their use as inhibitors |
ATE502928T1 (de) | 2000-11-01 | 2011-04-15 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
JP2002293773A (ja) * | 2001-03-30 | 2002-10-09 | Sumika Fine Chemicals Co Ltd | キナゾリン誘導体の製造方法 |
AU2002350105A1 (en) | 2001-06-21 | 2003-01-08 | Ariad Pharmaceuticals, Inc. | Novel quinazolines and uses thereof |
WO2003035602A1 (fr) * | 2001-10-25 | 2003-05-01 | Sankyo Company, Limited | Modulateurs lipidiques |
PL211694B1 (pl) * | 2001-12-24 | 2012-06-29 | Astrazeneca Ab | Podstawiona pochodna chinazoliny, jej zastosowania oraz jej kompozycja farmaceutyczna |
MXPA04006882A (es) | 2002-01-17 | 2004-12-06 | Neurogen Corp | Analogos substituidos de quinazolin-4-ilamina como moduladores de receptores de capsaicina. |
US6924285B2 (en) | 2002-03-30 | 2005-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
WO2004018430A1 (ja) * | 2002-08-23 | 2004-03-04 | Kirin Beer Kabushiki Kaisha | TGFβ阻害活性を有する化合物およびそれを含んでなる医薬組成物 |
SI1562955T1 (sl) | 2002-11-04 | 2008-06-30 | Astrazeneca Ab | Derivati kinazolina kot inhibitorji Src-triozin kinaze |
US7109337B2 (en) | 2002-12-20 | 2006-09-19 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
ES2338545T3 (es) | 2002-12-20 | 2010-05-10 | Pfizer Products Inc. | Derivados de pirimidina para el tratamiento del crecimiento celular anormal. |
AU2003299943A1 (en) * | 2002-12-23 | 2004-07-22 | Ariad Pharmaceuticals, Inc. | Heterocycles and uses thereof |
WO2004056801A1 (en) * | 2002-12-23 | 2004-07-08 | Astrazeneca Ab | Quinazoline derivatives |
WO2004056812A1 (en) * | 2002-12-23 | 2004-07-08 | Astrazeneca Ab | 4- (pyridin-4-ylamino) -quinazoline derivatives as anti-tumor agents |
WO2004058752A1 (en) | 2002-12-24 | 2004-07-15 | Astrazeneca Ab | Quinazoline compounds |
AU2003294142A1 (en) * | 2002-12-24 | 2004-07-22 | Astrazeneca Ab | Therapeutic quinazoline derivatives |
MY136174A (en) | 2002-12-24 | 2008-08-29 | Astrazeneca Ab | Phosphonooxy quinazoline derivatives and their pharmaceutical use |
KR20060003351A (ko) * | 2003-04-16 | 2006-01-10 | 아스트라제네카 아베 | 화합물 |
EP1635837B1 (en) * | 2003-06-02 | 2008-07-16 | AstraZeneca AB | (3-((quinazolin-4-yl)amino)-1h-pyrazol-1-yl)acetamide derivatives and related compounds as aurora kinase inhibitors for the treatment of proliferative diseases such as cancer |
WO2004108711A1 (en) * | 2003-06-05 | 2004-12-16 | Astrazeneca Ab | Pyrazinil quinazoline derivatives for use in the treatment of tumours |
WO2004108707A1 (en) * | 2003-06-05 | 2004-12-16 | Astrazeneca Ab | Pyridazinil quinazoline derivatives for use in the treatment of tumours |
WO2004108710A1 (en) * | 2003-06-05 | 2004-12-16 | Astrazeneca Ab | 4-pyrimidinyl quinazoline derivatives for use in the treatment of tumours |
TW200505452A (en) * | 2003-06-17 | 2005-02-16 | Astrazeneca Ab | Chemical compounds |
US7329664B2 (en) | 2003-07-16 | 2008-02-12 | Neurogen Corporation | Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues |
CN102432552B (zh) * | 2003-08-14 | 2016-01-20 | 阿雷生物药品公司 | 作为受体酪氨酸激酶抑制剂的喹唑啉类似物 |
GB0322409D0 (en) | 2003-09-25 | 2003-10-29 | Astrazeneca Ab | Quinazoline derivatives |
CA2537812C (en) | 2003-09-26 | 2013-01-22 | Exelixis, Inc. | C-met modulators and method of use |
DE602004022318D1 (de) * | 2003-10-14 | 2009-09-10 | Supergen Inc | Proteinkinaseinhibitoren |
US20090099165A1 (en) | 2003-10-14 | 2009-04-16 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Protein Kinase Inhibitors |
CA2540342A1 (en) * | 2003-10-31 | 2005-05-12 | Neurogen Corporation | 4-amino (aza) quinoline derivatives as capsaicin receptor agonists |
WO2005075439A1 (en) | 2004-02-03 | 2005-08-18 | Astrazeneca Ab | Quinazoline derivatives |
WO2005111022A1 (en) | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidines derivatives for the treatment of abnormal cell growth |
EP1756090A1 (en) | 2004-05-14 | 2007-02-28 | Pfizer Products Incorporated | Pyrimidine derivatives for the treatment of abnormal cell growth |
EP1758887A1 (en) | 2004-05-14 | 2007-03-07 | Pfizer Products Incorporated | Pyrimidine derivatives for the treatment of abnormal cell growth |
US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
TW200624431A (en) | 2004-09-24 | 2006-07-16 | Hoffmann La Roche | Phthalazinone derivatives, their manufacture and use as pharmaceutical agents |
MX2007004403A (es) | 2004-10-12 | 2007-04-27 | Astrazeneca Ab | Derivados de quinazolina. |
EP1812439B2 (en) | 2004-10-15 | 2017-12-06 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
WO2006104971A1 (en) * | 2005-03-28 | 2006-10-05 | Bristol-Myers Squibb Company | Atp competitive kinase inhibitors |
KR20070113286A (ko) | 2005-04-14 | 2007-11-28 | 에프. 호프만-라 로슈 아게 | 아미노피라졸 유도체, 이의 제조 및 약학 제제로서의 용도 |
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JP2010505962A (ja) | 2006-10-09 | 2010-02-25 | 武田薬品工業株式会社 | キナーゼ阻害剤 |
EP1921070A1 (de) | 2006-11-10 | 2008-05-14 | Boehringer Ingelheim Pharma GmbH & Co. KG | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung |
JP5377332B2 (ja) | 2007-02-06 | 2013-12-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 二環式へテロ環、それらの化合物を含む薬剤、その使用及びその製法 |
AU2008236670B2 (en) * | 2007-04-05 | 2011-12-01 | Amgen Inc. | Aurora kinase modulators and method of use |
CN101215274B (zh) * | 2007-12-27 | 2011-05-04 | 上海北卡医药技术有限公司 | N取代吗啉类有机化合物的制备工艺 |
PL2245026T3 (pl) | 2008-02-07 | 2013-01-31 | Boehringer Ingelheim Int | Spirocykliczne heterocykle, leki zawierające te związki, ich zastosowanie i sposób ich produkcji |
US8404694B2 (en) | 2008-03-20 | 2013-03-26 | Amgen Inc. | Aurora kinase modulators and method of use |
ES2444128T3 (es) | 2008-05-13 | 2014-02-24 | Astrazeneca Ab | Nueva SAL-554 |
CA2733153C (en) | 2008-08-08 | 2016-11-08 | Boehringer Ingelheim International Gmbh | Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them |
WO2010019473A1 (en) | 2008-08-14 | 2010-02-18 | Amgen Inc. | Aurora kinase modulators and methods of use |
WO2010045095A1 (en) | 2008-10-14 | 2010-04-22 | Ning Xi | Compounds and methods of use |
EP2241565A1 (en) | 2009-01-15 | 2010-10-20 | Universität Leipzig | Aurora kinase inhibitors compounds |
CA2995880C (en) | 2009-01-16 | 2021-01-05 | Exelixis, Inc. | Processes for preparing n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
AU2010229147B2 (en) * | 2009-03-21 | 2012-07-05 | Sunshine Lake Pharma Co., Ltd. | Amino ester derivatives, salts thereof and methods of use |
UA108618C2 (uk) | 2009-08-07 | 2015-05-25 | Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку | |
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GB201021103D0 (en) * | 2010-12-13 | 2011-01-26 | Univ Leuven Kath | New compounds for the treatment of neurodegenerative diseases |
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CA2935392C (en) | 2014-01-01 | 2022-07-26 | Medivation Technologies, Inc. | Amino pyridine derivatives for the treatment of conditions associated with excessive tgf.beta activity |
EP3319959B1 (en) | 2015-07-06 | 2021-09-01 | Alkermes, Inc. | Hetero-halo inhibitors of histone deacetylase |
EP3319968A1 (en) | 2015-07-06 | 2018-05-16 | Rodin Therapeutics, Inc. | Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase |
EP3184507A1 (en) * | 2015-12-22 | 2017-06-28 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Preparation of phenyl compounds |
WO2018132531A1 (en) | 2017-01-11 | 2018-07-19 | Rodin Therapeutics, Inc. | Bicyclic inhibitors of histone deacetylase |
SG11202000970WA (en) | 2017-08-07 | 2020-02-27 | Rodin Therapeutics Inc | Bicyclic inhibitors of histone deacetylase |
CN110746398A (zh) * | 2019-10-18 | 2020-02-04 | 刘沛友 | 4-杂环取代喹唑啉类衍生物及其制备方法和用途 |
CN114436975B (zh) * | 2022-01-26 | 2023-10-31 | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2-三氟甲基-4-氨基喹唑啉类化合物及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5710158A (en) | 1991-05-10 | 1998-01-20 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
US5721237A (en) * | 1991-05-10 | 1998-02-24 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties |
GB9800575D0 (en) * | 1998-01-12 | 1998-03-11 | Glaxo Group Ltd | Heterocyclic compounds |
US6258820B1 (en) * | 1999-03-19 | 2001-07-10 | Parker Hughes Institute | Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines |
CA2366998A1 (en) * | 1999-03-19 | 2000-09-28 | Mingshu Li | Quinazoline formulations and therapeutic use thereof |
-
1999
- 1999-09-21 GB GBGB9922171.5A patent/GB9922171D0/en not_active Ceased
-
2000
- 2000-09-19 HU HU0300205A patent/HUP0300205A3/hu unknown
- 2000-09-19 CZ CZ20021008A patent/CZ20021008A3/cs unknown
- 2000-09-19 CN CN00816012A patent/CN1391563A/zh active Pending
- 2000-09-19 KR KR1020027003680A patent/KR20020030123A/ko not_active Application Discontinuation
- 2000-09-19 TR TR2002/00717T patent/TR200200717T2/xx unknown
- 2000-09-19 US US10/088,856 patent/US7235559B1/en not_active Expired - Fee Related
- 2000-09-19 EE EEP200200118A patent/EE200200118A/xx unknown
- 2000-09-19 CA CA002384296A patent/CA2384296A1/en not_active Abandoned
- 2000-09-19 EP EP00960850A patent/EP1218355A1/en not_active Withdrawn
- 2000-09-19 IL IL14849600A patent/IL148496A0/xx unknown
- 2000-09-19 SK SK387-2002A patent/SK3872002A3/sk unknown
- 2000-09-19 PL PL00354870A patent/PL354870A1/xx not_active Application Discontinuation
- 2000-09-19 WO PCT/GB2000/003593 patent/WO2001021597A1/en not_active Application Discontinuation
- 2000-09-19 AU AU73019/00A patent/AU762697B2/en not_active Ceased
- 2000-09-19 JP JP2001524976A patent/JP2003509500A/ja active Pending
- 2000-09-19 BR BR0014137-2A patent/BR0014137A/pt not_active IP Right Cessation
- 2000-09-21 AR ARP000104956A patent/AR025735A1/es unknown
- 2000-09-21 CO CO00071838A patent/CO5200783A1/es not_active Application Discontinuation
-
2002
- 2002-03-18 BG BG106526A patent/BG106526A/xx unknown
- 2002-03-19 IS IS6310A patent/IS6310A/is unknown
- 2002-03-19 ZA ZA200202232A patent/ZA200202232B/en unknown
- 2002-03-20 NO NO20021400A patent/NO20021400L/no unknown
- 2002-11-19 HK HK02108371.0A patent/HK1046685A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CO5200783A1 (es) | 2002-09-27 |
BR0014137A (pt) | 2002-05-21 |
AU762697B2 (en) | 2003-07-03 |
KR20020030123A (ko) | 2002-04-22 |
EP1218355A1 (en) | 2002-07-03 |
EE200200118A (et) | 2003-04-15 |
AU7301900A (en) | 2001-04-24 |
NO20021400D0 (no) | 2002-03-20 |
HUP0300205A3 (en) | 2003-08-28 |
TR200200717T2 (tr) | 2002-06-21 |
ZA200202232B (en) | 2003-08-27 |
CA2384296A1 (en) | 2001-03-29 |
CN1391563A (zh) | 2003-01-15 |
SK3872002A3 (en) | 2002-12-03 |
US7235559B1 (en) | 2007-06-26 |
HK1046685A1 (zh) | 2003-01-24 |
GB9922171D0 (en) | 1999-11-17 |
PL354870A1 (en) | 2004-03-08 |
HUP0300205A2 (en) | 2003-05-28 |
CZ20021008A3 (cs) | 2002-06-12 |
BG106526A (en) | 2002-10-31 |
IS6310A (is) | 2002-03-19 |
WO2001021597A1 (en) | 2001-03-29 |
IL148496A0 (en) | 2002-09-12 |
NO20021400L (no) | 2002-05-06 |
JP2003509500A (ja) | 2003-03-11 |
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