PT902684E - Derivados hexa-hidro-pirido(4,3-b)indolo utilizados como farmacos antipsicoticos - Google Patents

Derivados hexa-hidro-pirido(4,3-b)indolo utilizados como farmacos antipsicoticos

Info

Publication number
PT902684E
PT902684E PT97924014T PT97924014T PT902684E PT 902684 E PT902684 E PT 902684E PT 97924014 T PT97924014 T PT 97924014T PT 97924014 T PT97924014 T PT 97924014T PT 902684 E PT902684 E PT 902684E
Authority
PT
Portugal
Prior art keywords
6alkyl
hydrogen
pct
formula
date nov
Prior art date
Application number
PT97924014T
Other languages
English (en)
Inventor
Ludo Edmond Josephine Kennis
Josephus Carolus Mertens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT902684E publication Critical patent/PT902684E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT97924014T 1996-05-23 1997-05-15 Derivados hexa-hidro-pirido(4,3-b)indolo utilizados como farmacos antipsicoticos PT902684E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201450 1996-05-23

Publications (1)

Publication Number Publication Date
PT902684E true PT902684E (pt) 2003-08-29

Family

ID=8224021

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97924014T PT902684E (pt) 1996-05-23 1997-05-15 Derivados hexa-hidro-pirido(4,3-b)indolo utilizados como farmacos antipsicoticos

Country Status (22)

Country Link
US (1) US6057325A (pt)
EP (1) EP0902684B1 (pt)
JP (1) JP2000510860A (pt)
CN (1) CN1149996C (pt)
AT (1) ATE236636T1 (pt)
AU (1) AU714113B2 (pt)
CA (1) CA2254755C (pt)
CY (1) CY2381B1 (pt)
CZ (1) CZ287961B6 (pt)
DE (1) DE69720715T2 (pt)
DK (1) DK0902684T3 (pt)
ES (1) ES2196332T3 (pt)
IL (1) IL127177A (pt)
MY (1) MY125562A (pt)
NO (1) NO311724B1 (pt)
NZ (1) NZ332310A (pt)
PL (1) PL187345B1 (pt)
PT (1) PT902684E (pt)
SI (1) SI0902684T1 (pt)
TW (1) TW470745B (pt)
WO (1) WO1997044040A1 (pt)
ZA (1) ZA974470B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1136493A1 (en) * 2000-03-23 2001-09-26 Sanofi-Synthelabo 2-(Thienopyridinyl)pyrimidone, 2-(furopyridinyl)pyrimidone 2-(isoquinolinyl)pyrimidone, 2-(pyridoindolyl)pyrimidone and 2-(benzofuropyridinyl)pyrimidone derivatives
MXPA04001203A (es) 2001-08-08 2004-05-20 Pharmacia & Upjhon Company 1-h-pirido[4,3-b] indoles terapeuticos.
JP4486505B2 (ja) * 2002-12-19 2010-06-23 ブリストル−マイヤーズ スクイブ カンパニー セロトニン・レセプタ作用薬および拮抗薬としての置換トリ環式ガンマ−カルボリン化合物
KR101168611B1 (ko) 2003-09-17 2012-08-03 얀센 파마슈티카 엔.브이. 세로토닌 수용체 조절자로서의 융합된 헤테로사이클릭 화합물
CN1882590B (zh) * 2003-09-17 2014-03-05 詹森药业有限公司 作为血清素受体调节剂的稠合杂环化合物
ES2319539T3 (es) * 2003-09-17 2009-05-08 Janssen Pharmaceutica Nv Compuestos heterociclicos condensados como moduladores del receptor de serotonina.
EP1944306A1 (en) * 2003-09-17 2008-07-16 Janssen Pharmaceutica, N.V. Fused heterocyclic compounds as serotonin receptor modulators
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
JP2010535220A (ja) * 2007-08-01 2010-11-18 メディベイション ニューロロジー， インコーポレイテッド 抗精神病用の併用療法剤を使用する統合失調症の治療のための方法および組成物
CN102316732B (zh) 2008-10-31 2015-04-01 梅迪维新技术公司 氮杂*并[4,5-b]吲哚以及使用方法
EP2346332A4 (en) 2008-10-31 2012-08-08 Medivation Technologies Inc PYRIDOÝ4,3-BINDOLES CONTAINING RIGID FRAGMENTS
US8791132B2 (en) 2011-02-18 2014-07-29 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
WO2014031167A1 (en) * 2012-08-22 2014-02-27 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents

Also Published As

Publication number Publication date
TW470745B (en) 2002-01-01
EP0902684B1 (en) 2003-04-09
IL127177A0 (en) 1999-09-22
JP2000510860A (ja) 2000-08-22
AU2961697A (en) 1997-12-09
CY2381B1 (en) 2004-06-04
AU714113B2 (en) 1999-12-16
NO311724B1 (no) 2002-01-14
CN1219875A (zh) 1999-06-16
CZ287961B6 (cs) 2001-03-14
IL127177A (en) 2003-10-31
NZ332310A (en) 1999-08-30
CZ377498A3 (cs) 1999-02-17
ATE236636T1 (de) 2003-04-15
PL187345B1 (pl) 2004-06-30
CA2254755C (en) 2007-01-16
NO985389L (no) 1999-01-20
DK0902684T3 (da) 2004-03-29
DE69720715T2 (de) 2004-03-11
EP0902684A1 (en) 1999-03-24
PL330079A1 (en) 1999-04-26
SI0902684T1 (en) 2003-10-31
CA2254755A1 (en) 1997-11-27
ZA974470B (en) 1998-11-23
MY125562A (en) 2006-08-30
WO1997044040A1 (en) 1997-11-27
ES2196332T3 (es) 2003-12-16
DE69720715D1 (en) 2003-05-15
NO985389D0 (no) 1998-11-19
CN1149996C (zh) 2004-05-19
US6057325A (en) 2000-05-02

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