AR022740A1 - Analogos opticamente puros de la camptotecina, composiciones farmaceuticas que los contienen y uso de los mismos como agentes antitumorales - Google Patents

Analogos opticamente puros de la camptotecina, composiciones farmaceuticas que los contienen y uso de los mismos como agentes antitumorales

Info

Publication number
AR022740A1
AR022740A1 ARP000100795A ARP000100795A AR022740A1 AR 022740 A1 AR022740 A1 AR 022740A1 AR P000100795 A ARP000100795 A AR P000100795A AR P000100795 A ARP000100795 A AR P000100795A AR 022740 A1 AR022740 A1 AR 022740A1
Authority
AR
Argentina
Prior art keywords
contain
pharmaceutical compositions
camptotechine
same
optically pure
Prior art date
Application number
ARP000100795A
Other languages
English (en)
Original Assignee
Ipsen Pharma Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma Sas filed Critical Ipsen Pharma Sas
Publication of AR022740A1 publication Critical patent/AR022740A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente se refiere en particular a los componentes de formula general (1) donde R1, R2, R3, R4, R5 y R6 representan varios radicales; su uso comomedicamentos y composiciones farmacéuticas que los contienen. Estos compuestos son particularmente usados para el tratamiento del cancer.
ARP000100795A 1999-02-26 2000-02-24 Analogos opticamente puros de la camptotecina, composiciones farmaceuticas que los contienen y uso de los mismos como agentes antitumorales AR022740A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9902398A FR2790261B1 (fr) 1999-02-26 1999-02-26 Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation

Publications (1)

Publication Number Publication Date
AR022740A1 true AR022740A1 (es) 2002-09-04

Family

ID=9542564

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000100795A AR022740A1 (es) 1999-02-26 2000-02-24 Analogos opticamente puros de la camptotecina, composiciones farmaceuticas que los contienen y uso de los mismos como agentes antitumorales

Country Status (29)

Country Link
US (1) US7012079B1 (es)
EP (2) EP1338599B1 (es)
JP (1) JP2002537399A (es)
KR (1) KR20010108270A (es)
CN (1) CN1195757C (es)
AR (1) AR022740A1 (es)
AT (2) ATE353902T1 (es)
AU (1) AU772632B2 (es)
BR (1) BR0008526A (es)
CA (1) CA2364705C (es)
CZ (1) CZ20013091A3 (es)
DE (2) DE60033447T2 (es)
DK (1) DK1165565T3 (es)
ES (2) ES2200829T3 (es)
FR (1) FR2790261B1 (es)
HK (1) HK1045514B (es)
HR (1) HRP20010622A2 (es)
HU (1) HUP0200529A3 (es)
IL (2) IL144987A0 (es)
MX (1) MXPA01008658A (es)
MY (1) MY127819A (es)
NO (1) NO327260B1 (es)
NZ (1) NZ514153A (es)
PL (1) PL202393B1 (es)
PT (1) PT1165565E (es)
RU (1) RU2230745C2 (es)
TW (1) TWI268931B (es)
WO (1) WO2000050427A1 (es)
ZA (1) ZA200107738B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
EP1794127A1 (en) * 2004-09-21 2007-06-13 Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) Novel processes for the production of useful intermediates
US8575484B1 (en) 2010-09-14 2013-11-05 Cooper Technologies Company Adjustable-depth ring assembly and method of installation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1114608C (zh) * 1995-06-21 2003-07-16 科学研究与运用咨询公司 喜树碱类似物、其制备方法和药物应用及其药物组合物
FR2757515B1 (fr) * 1996-12-20 2000-05-05 Sod Conseils Rech Applic Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
GB9512670D0 (en) * 1995-06-21 1995-08-23 Sod Conseils Rech Applic Camptothecin analogues
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2768431B1 (fr) 1997-08-29 2000-03-24 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
DK0925301T3 (da) * 1996-08-19 2004-07-12 Bionumerik Pharmaceuticals Inc Höjlipofile camptothecinderivater
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
EP1017675B1 (en) * 1997-02-14 2006-06-14 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
US6207673B1 (en) * 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof

Also Published As

Publication number Publication date
KR20010108270A (ko) 2001-12-07
DE60003170D1 (en) 2003-07-10
CN1345321A (zh) 2002-04-17
MXPA01008658A (es) 2002-03-14
FR2790261A1 (fr) 2000-09-01
IL144987A (en) 2006-12-31
DE60003170T2 (de) 2004-04-01
EP1338599A1 (fr) 2003-08-27
ATE242248T1 (de) 2003-06-15
HRP20010622A2 (en) 2002-08-31
TWI268931B (en) 2006-12-21
CN1195757C (zh) 2005-04-06
NO327260B1 (no) 2009-05-25
ES2200829T3 (es) 2004-03-16
PL202393B1 (pl) 2009-06-30
ZA200107738B (en) 2003-02-26
HUP0200529A2 (en) 2002-06-29
PT1165565E (pt) 2003-10-31
RU2230745C2 (ru) 2004-06-20
AU772632B2 (en) 2004-05-06
BR0008526A (pt) 2002-01-08
ES2282564T3 (es) 2007-10-16
DE60033447T2 (de) 2007-10-31
NO20014117L (no) 2001-10-11
EP1165565B1 (fr) 2003-06-04
MY127819A (en) 2006-12-29
PL361334A1 (en) 2004-10-04
EP1165565A1 (fr) 2002-01-02
AU2921000A (en) 2000-09-14
CA2364705A1 (fr) 2000-08-31
NO20014117D0 (no) 2001-08-24
HK1045514A1 (en) 2002-11-29
DK1165565T3 (da) 2003-10-06
CA2364705C (fr) 2010-03-30
HUP0200529A3 (en) 2004-03-29
US7012079B1 (en) 2006-03-14
NZ514153A (en) 2001-09-28
DE60033447D1 (de) 2007-03-29
EP1338599B1 (fr) 2007-02-14
IL144987A0 (en) 2002-06-30
WO2000050427A1 (fr) 2000-08-31
HK1045514B (zh) 2005-11-18
ATE353902T1 (de) 2007-03-15
CZ20013091A3 (cs) 2002-05-15
FR2790261B1 (fr) 2004-09-10
JP2002537399A (ja) 2002-11-05

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