ATE242248T1 - Optisch reine analoge der camptothecine - Google Patents

Optisch reine analoge der camptothecine

Info

Publication number
ATE242248T1
ATE242248T1 AT00907714T AT00907714T ATE242248T1 AT E242248 T1 ATE242248 T1 AT E242248T1 AT 00907714 T AT00907714 T AT 00907714T AT 00907714 T AT00907714 T AT 00907714T AT E242248 T1 ATE242248 T1 AT E242248T1
Authority
AT
Austria
Prior art keywords
camptothecines
optically pure
analogues
pure analogues
optically
Prior art date
Application number
AT00907714T
Other languages
English (en)
Inventor
Olivier Lavergne
Dennis Bigg
Christophe Lanco
Alain Rolland
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of ATE242248T1 publication Critical patent/ATE242248T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT00907714T 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine ATE242248T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9902398A FR2790261B1 (fr) 1999-02-26 1999-02-26 Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
PCT/FR2000/000461 WO2000050427A1 (fr) 1999-02-26 2000-02-24 Analogues optiquement purs de la camptothecine

Publications (1)

Publication Number Publication Date
ATE242248T1 true ATE242248T1 (de) 2003-06-15

Family

ID=9542564

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00907714T ATE242248T1 (de) 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine
AT03075924T ATE353902T1 (de) 1999-02-26 2000-02-24 Optisch reine camptothecin-analoge

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03075924T ATE353902T1 (de) 1999-02-26 2000-02-24 Optisch reine camptothecin-analoge

Country Status (29)

Country Link
US (1) US7012079B1 (de)
EP (2) EP1165565B1 (de)
JP (1) JP2002537399A (de)
KR (1) KR20010108270A (de)
CN (1) CN1195757C (de)
AR (1) AR022740A1 (de)
AT (2) ATE242248T1 (de)
AU (1) AU772632B2 (de)
BR (1) BR0008526A (de)
CA (1) CA2364705C (de)
CZ (1) CZ20013091A3 (de)
DE (2) DE60003170T2 (de)
DK (1) DK1165565T3 (de)
ES (2) ES2200829T3 (de)
FR (1) FR2790261B1 (de)
HK (1) HK1045514B (de)
HR (1) HRP20010622A2 (de)
HU (1) HUP0200529A3 (de)
IL (2) IL144987A0 (de)
MX (1) MXPA01008658A (de)
MY (1) MY127819A (de)
NO (1) NO327260B1 (de)
NZ (1) NZ514153A (de)
PL (1) PL202393B1 (de)
PT (1) PT1165565E (de)
RU (1) RU2230745C2 (de)
TW (1) TWI268931B (de)
WO (1) WO2000050427A1 (de)
ZA (1) ZA200107738B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
CA2580747A1 (en) * 2004-09-21 2006-03-30 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R .A.S.) Novel processes for the production of useful intermediates
US8575484B1 (en) 2010-09-14 2013-11-05 Cooper Technologies Company Adjustable-depth ring assembly and method of installation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2768431B1 (fr) 1997-08-29 2000-03-24 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
FR2757515B1 (fr) * 1996-12-20 2000-05-05 Sod Conseils Rech Applic Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
GB9512670D0 (en) * 1995-06-21 1995-08-23 Sod Conseils Rech Applic Camptothecin analogues
PT835258E (pt) * 1995-06-21 2003-02-28 Sod Conseils Rech Applic Novos analogos de camptotecina, processos para a sua preparacao, sua utilizacao como farmacos e composicoes farmaceuticas que os contem
KR100516593B1 (ko) * 1996-08-19 2005-09-22 바이오누머릭 파마슈티칼스, 인코포레이티드 고 친유성 캠프토테신 유도체
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
WO1998035940A1 (en) 1997-02-14 1998-08-20 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
US6207673B1 (en) * 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof

Also Published As

Publication number Publication date
JP2002537399A (ja) 2002-11-05
HK1045514B (zh) 2005-11-18
ATE353902T1 (de) 2007-03-15
US7012079B1 (en) 2006-03-14
AU2921000A (en) 2000-09-14
PT1165565E (pt) 2003-10-31
CN1195757C (zh) 2005-04-06
FR2790261A1 (fr) 2000-09-01
DE60003170D1 (en) 2003-07-10
HK1045514A1 (en) 2002-11-29
DE60033447D1 (de) 2007-03-29
EP1338599B1 (de) 2007-02-14
NO20014117D0 (no) 2001-08-24
AR022740A1 (es) 2002-09-04
CA2364705A1 (fr) 2000-08-31
HUP0200529A3 (en) 2004-03-29
HUP0200529A2 (en) 2002-06-29
DK1165565T3 (da) 2003-10-06
NZ514153A (en) 2001-09-28
IL144987A (en) 2006-12-31
ES2200829T3 (es) 2004-03-16
DE60033447T2 (de) 2007-10-31
HRP20010622A2 (en) 2002-08-31
RU2230745C2 (ru) 2004-06-20
MY127819A (en) 2006-12-29
NO20014117L (no) 2001-10-11
FR2790261B1 (fr) 2004-09-10
EP1165565A1 (de) 2002-01-02
AU772632B2 (en) 2004-05-06
BR0008526A (pt) 2002-01-08
IL144987A0 (en) 2002-06-30
EP1338599A1 (de) 2003-08-27
CN1345321A (zh) 2002-04-17
TWI268931B (en) 2006-12-21
CA2364705C (fr) 2010-03-30
ZA200107738B (en) 2003-02-26
MXPA01008658A (es) 2002-03-14
PL202393B1 (pl) 2009-06-30
ES2282564T3 (es) 2007-10-16
PL361334A1 (en) 2004-10-04
NO327260B1 (no) 2009-05-25
WO2000050427A1 (fr) 2000-08-31
DE60003170T2 (de) 2004-04-01
CZ20013091A3 (cs) 2002-05-15
KR20010108270A (ko) 2001-12-07
EP1165565B1 (de) 2003-06-04

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