DE60033447D1 - Optisch reine Camptothecin-Analoge - Google Patents

Optisch reine Camptothecin-Analoge

Info

Publication number
DE60033447D1
DE60033447D1 DE60033447T DE60033447T DE60033447D1 DE 60033447 D1 DE60033447 D1 DE 60033447D1 DE 60033447 T DE60033447 T DE 60033447T DE 60033447 T DE60033447 T DE 60033447T DE 60033447 D1 DE60033447 D1 DE 60033447D1
Authority
DE
Germany
Prior art keywords
optically pure
camptothecin analogues
pure camptothecin
analogues
optically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60033447T
Other languages
English (en)
Other versions
DE60033447T2 (de
Inventor
Olivier Lavergne
Dennis Bigg
Christophe Lanco
Alain Rolland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Application granted granted Critical
Publication of DE60033447D1 publication Critical patent/DE60033447D1/de
Publication of DE60033447T2 publication Critical patent/DE60033447T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60033447T 1999-02-26 2000-02-24 Optisch reine Camptothecin-Analoge Expired - Lifetime DE60033447T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9902398 1999-02-26
FR9902398A FR2790261B1 (fr) 1999-02-26 1999-02-26 Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation

Publications (2)

Publication Number Publication Date
DE60033447D1 true DE60033447D1 (de) 2007-03-29
DE60033447T2 DE60033447T2 (de) 2007-10-31

Family

ID=9542564

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60033447T Expired - Lifetime DE60033447T2 (de) 1999-02-26 2000-02-24 Optisch reine Camptothecin-Analoge
DE60003170T Expired - Lifetime DE60003170T2 (de) 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60003170T Expired - Lifetime DE60003170T2 (de) 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine

Country Status (29)

Country Link
US (1) US7012079B1 (de)
EP (2) EP1338599B1 (de)
JP (1) JP2002537399A (de)
KR (1) KR20010108270A (de)
CN (1) CN1195757C (de)
AR (1) AR022740A1 (de)
AT (2) ATE353902T1 (de)
AU (1) AU772632B2 (de)
BR (1) BR0008526A (de)
CA (1) CA2364705C (de)
CZ (1) CZ20013091A3 (de)
DE (2) DE60033447T2 (de)
DK (1) DK1165565T3 (de)
ES (2) ES2200829T3 (de)
FR (1) FR2790261B1 (de)
HK (1) HK1045514B (de)
HR (1) HRP20010622A2 (de)
HU (1) HUP0200529A3 (de)
IL (2) IL144987A0 (de)
MX (1) MXPA01008658A (de)
MY (1) MY127819A (de)
NO (1) NO327260B1 (de)
NZ (1) NZ514153A (de)
PL (1) PL202393B1 (de)
PT (1) PT1165565E (de)
RU (1) RU2230745C2 (de)
TW (1) TWI268931B (de)
WO (1) WO2000050427A1 (de)
ZA (1) ZA200107738B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
EP1794127A1 (de) * 2004-09-21 2007-06-13 Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) Neue verfahren zur herstellung von nützlichen zwischenprodukten
US8575484B1 (en) 2010-09-14 2013-11-05 Cooper Technologies Company Adjustable-depth ring assembly and method of installation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1114608C (zh) * 1995-06-21 2003-07-16 科学研究与运用咨询公司 喜树碱类似物、其制备方法和药物应用及其药物组合物
FR2757515B1 (fr) * 1996-12-20 2000-05-05 Sod Conseils Rech Applic Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
GB9512670D0 (en) * 1995-06-21 1995-08-23 Sod Conseils Rech Applic Camptothecin analogues
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2768431B1 (fr) 1997-08-29 2000-03-24 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
DK0925301T3 (da) * 1996-08-19 2004-07-12 Bionumerik Pharmaceuticals Inc Höjlipofile camptothecinderivater
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
EP1017675B1 (de) * 1997-02-14 2006-06-14 Bionumerik Pharmaceuticals, Inc. Hochgradig lipophile camptothecin-derivate
US6207673B1 (en) * 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof

Also Published As

Publication number Publication date
KR20010108270A (ko) 2001-12-07
DE60003170D1 (en) 2003-07-10
CN1345321A (zh) 2002-04-17
MXPA01008658A (es) 2002-03-14
FR2790261A1 (fr) 2000-09-01
IL144987A (en) 2006-12-31
DE60003170T2 (de) 2004-04-01
EP1338599A1 (de) 2003-08-27
ATE242248T1 (de) 2003-06-15
HRP20010622A2 (en) 2002-08-31
TWI268931B (en) 2006-12-21
CN1195757C (zh) 2005-04-06
NO327260B1 (no) 2009-05-25
ES2200829T3 (es) 2004-03-16
PL202393B1 (pl) 2009-06-30
ZA200107738B (en) 2003-02-26
HUP0200529A2 (en) 2002-06-29
PT1165565E (pt) 2003-10-31
RU2230745C2 (ru) 2004-06-20
AU772632B2 (en) 2004-05-06
BR0008526A (pt) 2002-01-08
ES2282564T3 (es) 2007-10-16
DE60033447T2 (de) 2007-10-31
NO20014117L (no) 2001-10-11
EP1165565B1 (de) 2003-06-04
MY127819A (en) 2006-12-29
PL361334A1 (en) 2004-10-04
EP1165565A1 (de) 2002-01-02
AU2921000A (en) 2000-09-14
CA2364705A1 (fr) 2000-08-31
NO20014117D0 (no) 2001-08-24
HK1045514A1 (en) 2002-11-29
DK1165565T3 (da) 2003-10-06
CA2364705C (fr) 2010-03-30
HUP0200529A3 (en) 2004-03-29
US7012079B1 (en) 2006-03-14
NZ514153A (en) 2001-09-28
EP1338599B1 (de) 2007-02-14
IL144987A0 (en) 2002-06-30
WO2000050427A1 (fr) 2000-08-31
HK1045514B (zh) 2005-11-18
AR022740A1 (es) 2002-09-04
ATE353902T1 (de) 2007-03-15
CZ20013091A3 (cs) 2002-05-15
FR2790261B1 (fr) 2004-09-10
JP2002537399A (ja) 2002-11-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR